Online NMR spectroscopy paves the way for short development times in industrial reaction and process monitoring
- Modular chemical production is a tangible implementation of the digital transformation of the specialty chemicals process industry. In particular, it enables acceleration of process development and thus faster time to market by flexibly interconnecting and orchestrating standardized physical modules and bringing them to life. For this purpose, specific (chemical) sensors of process analytics are needed, preferably without lengthy calibration or spectroscopic model development.
An excellent example of a "direct" analytical method is online nuclear magnetic resonance (NMR) spectroscopy. NMR spectroscopy meets the requirements of a direct analytical method because of the direct correlation between the signal area in the spectrum ("counting" the nuclear spins) and the analyte amount of substance concentrations. It is also extremely linear over the concentration range.
With the availability of compact benchtop NMR instruments, it is now possible to bring NMR spectroscopy directly into theModular chemical production is a tangible implementation of the digital transformation of the specialty chemicals process industry. In particular, it enables acceleration of process development and thus faster time to market by flexibly interconnecting and orchestrating standardized physical modules and bringing them to life. For this purpose, specific (chemical) sensors of process analytics are needed, preferably without lengthy calibration or spectroscopic model development.
An excellent example of a "direct" analytical method is online nuclear magnetic resonance (NMR) spectroscopy. NMR spectroscopy meets the requirements of a direct analytical method because of the direct correlation between the signal area in the spectrum ("counting" the nuclear spins) and the analyte amount of substance concentrations. It is also extremely linear over the concentration range.
With the availability of compact benchtop NMR instruments, it is now possible to bring NMR spectroscopy directly into the field, in close proximity to specialized laboratory facilities, pilot plants, and even industrial-scale production facilities. The first systems are in TRL 8 (Qualified System with Proof of Functionality in the Field).
The presentation will discuss the many building blocks of online nuclear magnetic resonance spectroscopy, from flow cells to automated data analysis.…
Autor*innen: | Michael MaiwaldORCiD |
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Dokumenttyp: | Vortrag |
Veröffentlichungsform: | Präsentation |
Sprache: | Englisch |
Jahr der Erstveröffentlichung: | 2023 |
Organisationseinheit der BAM: | 1 Analytische Chemie; Referenzmaterialien |
1 Analytische Chemie; Referenzmaterialien / 1.4 Prozessanalytik | |
DDC-Klassifikation: | Naturwissenschaften und Mathematik / Chemie / Analytische Chemie |
Freie Schlagwörter: | Automation; Industry 4.0; Modular Production; Online NMR Spectroscopy; Process Monitoring; Reaction Monitoring |
Themenfelder/Aktivitätsfelder der BAM: | Chemie und Prozesstechnik |
Chemie und Prozesstechnik / Chemische Charakterisierung und Spurenanalytik | |
Umwelt | |
Umwelt / Sensorik | |
Veranstaltung: | SFB 1527 HyPERiON “High Performance Compact Magnetic Resonance“ Online Seminar |
Veranstaltungsort: | Karlsruhe, Germany |
Beginndatum der Veranstaltung: | 06.07.2023 |
Enddatum der Veranstaltung: | 06.07.2023 |
Verfügbarkeit des Dokuments: | Datei im Netzwerk der BAM verfügbar ("Closed Access") |
Datum der Freischaltung: | 06.07.2023 |
Referierte Publikation: | Nein |
Eingeladener Vortrag: | Nein |