Fakultät Maschinenbau
Refine
Year of publication
Document Type
- conference proceeding (presentation, abstract) (56) (remove)
Is part of the Bibliography
- no (56)
Keywords
- CFD (2)
- Aerodynamics (1)
- Aerosols (1)
- Bildbasierte Verfahren (1)
- Bildgebendes Verfahren (1)
- Blood Viscosity (1)
- Blutdruck (1)
- Blutgefäß (1)
- Dragonfly (1)
- Ellenbogenstabilität (1)
- Endotracheal Intubation (1)
- Flow visualisation (1)
- Gliding Flight (1)
- Hämodynamik (1)
- Kardiovaskuläres System (1)
- Membrane Oxygenator (1)
- Muskuloskelettale Simulation (1)
- Nasal airflow (1)
- Physiological Breathing (1)
- Shear Raed Induced Coagulation (1)
- Silent Breathing (1)
- Stent (1)
- Tomographic PIV (1)
- additive manufacturing (1)
- biomechanics (1)
- composites (1)
- continuous fiber (1)
- discrete event simulation (1)
- esb (1)
- factory planning (1)
- humeroradial stability (1)
- muscle recruitment (1)
- radial head arthroplasty (1)
- radial head prostheses (1)
- replenishment strategies (1)
- space requirements (1)
- subluxation (1)
- supply chain management (1)
- toolpath (1)
Institute
- Fakultät Maschinenbau (56)
- Regensburg Center of Biomedical Engineering - RCBE (27)
- Labor Biomechanik (LBM) (18)
- Regensburg Center of Health Sciences and Technology - RCHST (10)
- Labor Biofluidmechanik (9)
- Combustion Engines and Emissions Control Laboratory (CEEC) (5)
- Labor CAD/CAE (5)
- Labor Mehrkörpersimulation (MKS) (5)
- Labor Laser-Materialbearbeitung (LMP) (4)
- Labor Finite-Elemente-Methode (FEM) (3)
Begutachtungsstatus
- begutachtet (7)
- peer-reviewed (7)
Developing new deep-drawn sheet metal parts is a challenging task due to conflicting demands for low costs, durability, and crash properties. Ensuring manufacturability throughout geometrical changes adds to the complexity, leading engineers to rely on experience-driven iterative design changes that compromise requirements and lack reproducibility. Finite Element (FE) simulation models are employed to ensure manufacturability, albeit at the expense of high computational costs and delays in part development.
To improve efficiency, a Machine learning (ML)-centered approach was proposed to ensure manufacturability. However, the limited availability of data raises uncertainty about whether a low- or high-dimensional ML approach is most suitable for drawability assessment.
This work compares the accuracy of a low-dimensional, feature-based Linear Support Vector surrogate and an adapted high-dimensional PointNet model under different dataset sizes. The dataset is composed of parametrically generated, U-shaped structural sheet metal parts.
We use a one-step simulation scheme and evaluate results with a Forming Limit Diagram (FLD) to label drawability. Results show the point of transition to be at about 500 training samples, from which onwards Deep learning is advantageous.
Moreover, the generalizability of these models is tested on a second dataset with topologically similar components. This is to assess the potential for a geometrically more comprehensive evaluation. We discuss several influences on model performances and outline future potentials.
Increasing the lifetime of titanium implants through a diffusion-controlled surface treatment
(2023)
Introduction
Shear induced multimerisation of von-Willebrand-factor (vWF) is supposed to play an important role in coagulation inside extracorporeal membrane oxygenators. However, there is no proof that links observed vWF structures to computed or measured flow conditions.
Methods
The structures of multimeric vWF fibers, observed in clinically used membrane oxygenators is examined using immunofluorescence microscopy (IFM) using Carstairs’ staining method (positive ethics committee vote). The flow around the membrane fibres inside the oxygenator is investigated in terms of shear rate, wall shear velocity and streamlines by using CFD (RANS, Carreau-Yasuda viscosity, geometry remodelled after high-resolution µCT-scans). By interpreting the histological and numerical results in this common context, indications for shear induced coagulation mechanisms can be identified.
Results
The fibre structures of multimeric vWF build regular but not exactly symmetric formations around the contact face (CF) between the crosswise stacked oxygenator fibres (OF), see fig.1B, vWF marked red. Annular around the CF arranged, cells are likely to be found, see fig.1B, nuclei marked blue.
The computed streamlines around the OF show attached flow around the circular fibres. However, the irregular arrangement of real OF produce considerable cross flow between the interconnected neighbouring channels, in contrast to previous 2D-simulations. Thus, the CF are washed around closely by blood, also from neighbouring channels. The wall shear velocity streamlines form regular, slightly asymmetric shapes around the contact faces. The occurring maximum shear rates are in the range of 1,000 1/s.
Discussion
The shapes of vWF structures found in clinically used oxygenators match the computational results in terms of wall shear velocity and streamlines well. The accumulation of cells close to the CF can also be explained by fluid mechanics, as there are small shear gradients and slow velocities. However, occurring shear rates between OFs are too low to trigger multimerisation of vWF. That raises the question where in the circuit the actual activation of vWF is started and how, at least partly chained, vWF multimeres are attracted towards the OF surface. A next step will be the investigation of the actual shear rate triggered (or mediated) multimerisation of vWF. Towards this end, microfluidic experiments with shear triggered coagulation will be performed. Also of big interest is the computation of the flow situation in the oxygenator in proximity to chaining threads, which have been ignored in computations so far. However, first a realistic representation of the effective viscosity in computations is needed, which is not available yet.
One major goal of green-field factory planning is to decide on space requirements in the plant. In this phase, detailed information about the supply chain network (e.g. which suppliers deliver which parts) is often unavailable. Nevertheless, typical decisions in supply chain management, like the definition of replenishment processes and quantities or make-or-buy decisions, impact space requirements in the factory and should therefore be considered in the factory planning. This research article proposes a simulation approach for a factory simulation in which raw material replenishment is integrated to evaluate the space requirements for raw materials.
Feasibility of detecting thrombotic deposits in membrane oxygenators using micro computed tomography
(2019)
To detect convective gas flow inside the large airways during high frequency oscillated ventilation (HFOV) the fluorinated contrast gas Heptafluoropropane was used for 19F-MRI. In a first study the comparison between constant flow measurements and Computational Fluid Dynamics (CFD) simulations provided a good agreement. In a following experiment oscillated flow was applied to a lung phantom consisting of ventilation bag and long pipe. The pressure wave inside the pipe was explored point-by-point and corresponding velocities were determined. With these experiments it could be shown for the first time that flow measurement during HFOV using fluorinated contrast gas is feasible.
The special wing geometry of dragonflies consisting of veins and a membrane forming a corrugated profile leads to special aerodynamic characteristics. To capture the governing flow regimes of a dragonfly wing in detail, a realistic wing model has to be investigated. Therefore, this study aimed to analyze the aerodynamic characteristics of a 3D dragonfly wing reconstructed from a high-resolution micro-CT scan. Afterwards, a spatially high discretized mesh was generated using the mesh generator CENTAUR™ 14.5.0.2 (CentaurSoft, Austin, TX, US) to finally conduct Computational Fluid Dynamics (CFD) investigations in Fluent® 2020 R2 (ANSYS, Inc., Canonsburg, PA, US). Due to the small dimensions of the wing membrane, only the vein structure of a Camacinia Gigantea was captured at a micro-CT voxel size of 7 microns. The membrane was adapted and connected to the vein structure using a Boolean union operation. Occurring nconsistencies after combining the veins and the membrane were corrected using an adapted pymesh script [1]. As an initial study, only one quarter of the wing (outer wing section) was investigated to reduce the required computational effort. The resulting hybrid mesh consisting of 10 pseudo-structured prism layers along the wing surface and tetrahedra in the farfield area has 43 mio. nodes. The flow around the wing was considered to be incompressible and laminar using transient calculations. When the flow passes the vein structures, steady vortices occur in the corrugation valleys leading to recirculation zones. Therefore, the dragonfly wing resembles the profile of an airfoil. This leads to comparable lift coefficients of dragonfly wings and airfoil profiles at significantly reduced structural weight. The reconstructed geometry also included naturally occurring triangular prismlike serrated structures at the leading edge of the wing, which have comparable effects to micro vortex generators and might stabilize the recirculation zones. Further work aims to investigate the aerodynamic properties of a complete dragonfly wing during wing flapping.
Air leakage past High-Volume-Low-Pressure (HVLP) endotracheal tube (ETT) cuffs creates a potential infection risk for health care professionals during ventilation of patients suffering from contagious airborne diseases. However, unlike silent aspiration, a phenomenon where fluids enter the airways of intubated patients, the aspect of aerosol emergence through cuff folds -what we called accordingly “silent breathing” (SB)- has not been investigated in detail so far.
This study investigates air leakage past HVLP cuffs with varying cuff pressures under realistic artificial breathing scenarios experimentally and in addition numerically. The focus was laid on the parametric investigation of the occurrence and furthermore on different influencing factors of silent breathing. The morphology of the folds responsible for the leakage was captured using high-resolution 3D microcomputed tomography (μCT). For the numerical investigations (Com-putational Fluid Dynamics - CFD), the commercial CFD Software package FLUENT 2021 R2 (ANSYS, Inc., Canonsburg, PA, US), as well as the DLR in-house research code THETA has been used.
High Spatial Resolution Tomo-PIV of the Nasopharynx Focussing on the Physiological Breathing Cycle
(2022)
Investigations of complex patient-specific flow in the nasopharynx requires high resolution numerical calculations validated by reliable experiments. When building the validation base and the benchmark
of computational fluid dynamics, an experimental setup of the nasal airways was developed. The applied optical measurement technique of tomo-PIV supplies information on the governing flow field in three dimensions. This paper presents tomo-PIV measurements of the highly complex patient-specific geometry of the human trachea. A computertomographic scan of a person’s head builds the basis of the experimental silicone model of the nasal airways. An optimised approach for precise refractive index matching avoids optical distortions even in highly complex non-free-of-sight 3D geometries. A linear-motor-driven pump generates breathing scenarios, based on measured breathing cycles. Adjusting of the CCD cameras‘ double-frame-rate PIV-Δt enables the detailed analysis of flow structures during different cycle phases. Merging regions of interest enables high spatial resolution acquisition of the flow field.
Surgical smoke has been a little discussed topic in the context of the current pandemic. Surgical smoke is generated during the cauterization of tissue with heat-generating devices and consists of 95% water
vapor and 5% cellular debris in the form of particulate matter. In-vivo investigations are performed during tracheotomies where surgical smoke is produced during tissue electrocautery. Furthermore, in-vitro parametric studies to investigate the particle number and size distribution and the spatial distribution of surgical smoke with laser light sheet technique are conducted. The higher the power of the high-frequency-device the larger the particles in size and the higher the resulting particle counts. The images taken show the densest smoke at 40W with artificial saliva. The resulting characteristic size distribution, which may include viruses and bacterial components, confirms that the risk arising from surgical smoke should be considered. Furthermore, the experiments will provide the database for further numerical investigations.
Modelling blood flow an shear induced coagulation in membraene oxygenators (MO) is challenging. The relevant geometry of oxygenator fibers (OF) and chaining threads is complex and spans several length scales. In relevant scales and regimes blood shows several significant non-Newtonian effects. Existing models are only capable of accounting for some, but not all relevant effects. Additionally, coagulation processes are influencing fluid properties and geometry significantly. Due to the enormous size of the discretised geometries highly detailed viscosity and coagulation properties of blodd flow in MOs. First step is to find a gemoetry dependent viscosity representation on basis of parametric micro channel experiments with anti-coagulated blood. Next step is a statistic coagulation model, based on micro channel experiments with human (re-calcified citrated) whole blood an evaluation of clinically used osygenators. Since shear rate dependent (i.e. viscosity dependet) coagulation in return influences the viscosity, a combined model with suitable implementation in a RANS framework is necessary. Towards this end, micro channel experiments with new and used single OFs triggering coagulation are performed. Structures of multimeric von Willebrand fibers (vWF), as indicator for shear induced coagulation, are compared to computed and measured flow conditions, using immunofluorescence microscopy, RANS-computations and µPIV, respectively. Preliminary examinations in clinically used MOs show good agreement between occurring structures of vWF, cell depositions and computed flow patterns (geometry form µCT-Scans). However, computed shear rates might be to low to actually trigger activation of vWF. The complex geometry of MOs results in huge meshes, which makes RANS with statistical modelling of viscosity and coagulation a reasonable approach. Towards this end, experimental data on micro channel level with evaluation on real application level is crucial. Especially regarding clotting processes, micro fluidic experiments are powerful research tool.
Patients with juvenile retinal dystrophy often report that they are unaware of their central scotoma, suggesting the presence of perceptual filling-in. We used functional Magnetic Resonance Imaging (fMRI) to determine possible neural correlates of perceptual filling-in in patients with retinal distrophy and clinically established central scotoma in both eyes. The data of 5 patients (Stargardt disease, cone-rod dystrophy; mean age 45 yrs; scotoma diameter 10-20°) and of 5 normally sighted controls were analyzed. Fixation behaviour and perimetry were measured with a Nidek microperimeter. Magnetic resonance imaging was performed using a Siemens 3T Allegra scanner. We stimulated the central visual field (30 deg) with a vertically oriented, low spatial frequency (1 c/deg) high-contrast sinewave grating that was either a) continuous, or b) was interrupted by a central grey disk. The disk was either slightly larger than the scotoma (detectable on 75% of trials) or slightly smaller (detectable on 25% of trials). To control for attention, an eccentric fixation task was performed during scanning. Data were analyzed using SPM8 (GLM with ROI analysis to obtain percent signal change for foveal projection zone). Results: for all patients, the BOLD signal in the foveal projection area was significantly higher for the small disk (i.e., condition leading to complete filling-in) than for the large disk (i.e., no filling-in). This effect was absent in the control subjects. Our findings support the existence of an active neural process that leads to filling-in in patients with central visual field scotomata.
Additive Fertigung hat sich in zahlreichen industriellen Anwendungen etabliert und bildet eine wichtige Schlüsseltechnologie. Im Gegensatz zu metallischen Werkstoffen, haben additiv gefertigte Bauteile aus Kunststoffen geringere Festigkeit und Steifigkeit, sodass sich ihre Verwendung als lasttragende Strukturen schwierig gestaltet. Insbesondere der Einsatz von endlosen Verstärkungsfasern kann die mechanischen Eigenschaften additiv gefertigter Strukturen signifikant verbessern und die Fertigung hochbelastbarer Faserverbundstrukturen im 3D-Druckverfahren ermöglichen. Daher gilt es aktuell notwendige Anlagen und Prozessketten für den Fertigungsprozess aber auch Vorgehensweisen für die belastungsoptimierte Auslegung der Faserverläufe innerhalb des Bauteils zu entwickeln, um so das Themengebiet „Endlosfaserverstärkter 3D-Druck“ weiter voranzutreiben. Für mehr räumliche Freiheit bei der Positionierung der Druckbahnen können industrieroboterbasierte Systeme eingesetzt werden, um so das Potenzial gerichteter Bauweise von Faserverbundstrukturen auch im additiven Fertigungsprozess vollumfänglich ausschöpfen zu können. Dabei ermöglicht ihr Einsatz auch eine räumliche Ablage der Faserverstärkung, wobei für die Materialablage ein geeigneter 3D-Druckkopf erforderlich ist. Für die Implementierung der Faserverstärkung ist zudem eine dem Lastfall entsprechende Auslegung des Bauteils sowie die Ermittlung einer sinnvollen Faserpositionierung innerhalb des Bauteils erforderlich, wobei unterschiedliche Variablen aus den Bereichen Material, Struktur und Fertigungsprozess berücksichtigt werden müssen. Im Rahmen des Vortrages werden die Herausforderungen der Technologieentwicklung des endlosfaserverstärkten 3D-Drucks aufgegriffen sowie auf eine belastungsorientierte Faserpositionierung näher eingegangen. Aktuelle Erkenntnisse werden diskutiert sowie eine Entwurfsmethodik für die Prozesspfadgenerierung vorgeschlagen.
In practical use cases, simulation engineers are confronted with uncertainties in the simulation parameters. Normally, trust in a model is built from experience, practical assumptions, and parameter studies. This approach, though, is based on the assumption that few parameter combinations are sufficient to represent the whole design space. This lacks an appraisable mathematical basis.
To get insights into which parameters most strongly affect the results, a global sensitivity analysis can be conducted [2, 3]. The results are utilized to rank the most influential parameters and to filter less relevant ones. This gives feedback which improved set of input data will lead to more certainty in the simulation results. To enable this in the framework of multi-fidelity analysis and optimization, we compare here global sensitivities and uncertainties of the implicit One-Step approach (low-fidelity) with those of the explicit multi-step deep drawing approach (high-fidelity).
The primary consumers of plant exudates – in exact fungi and bacteria, are representative for the soil succession level from bare soil, which is bacterial dominant to old growth forest constitute by fungal dominance. In a specified level of soil succession, a special kind of plant family benefits on the Fungal to Bacteria Ratio. The ability to determine this ratio in situ without complex chemical applications is part of the project Electronical Laboratory for Intelligent Soil Examination (ELISE). Several mechanical and optical tests on soil samples are covered within this Project. To analyze the fungal to bacteria ratio, samples are prepared automatically – in a defined and reproductive procedure – to generate slides for shadowing microscopy. The samples are observed by a camera, which is attached to a transmitted light microscope. The automatic analysis, done with computer vision algorithms, aims to quantify bacterial and fungal biomass in the actual sample view. Moreover, the algorithm can classify organisms according to their color and shape.
To get a processable picture, several images from different focal levels must be taken through the sample thickness. Parts of each image, are in focus at the actual layer, are merged to a whole depth of field picture, by focus stacking.
This produced picture is used to classify, locate and quantify – in first step filamentous organisms e.g. fungal by image sematic segmentation. The result represents an image sized mask, which indicates the class of fungi with class equivalate values at the pixel positions – covered by the organism. This information is used to calculate the fungal mass per gram soil.
To quantify the bacterial biomass two approaches are implemented. For low density of bacterial existence, the individual bacteria is counted for a part of the field of view by an image detection algorithm to be extrapolate afterwards to the mass per gram soil. For high density of bacterial occurrence, specified regions of interest with only bacteria present are chosen. An image classification which has been pretrained by pictures of bacterial density patterns – previously determent by making the sample countable due to preforming sample dilutions, is done. The second option for high density bacterial count is, to automatically preform dilutions until the image detection is confidently countable.
To ensure a usable confidence score a statistical approach of many fields of view is taken.
The sample preparation for shadowing microscopy, to examinate biological soil properties, is time consuming, manual work. The outcome depends on subjective skills of the operator, furthermore the results are mostly not quantitative. The database on biological soil properties is mostly not sufficient for an integrated modelling on an multidisciplinary scale. This project combines three progressive approaches to develop a tool that is easy to use and gives in situ results that can be used for many purposes.
Background:
Brain lesions in language-related cortical areas remain a challenge in the clinical routine. In recent years the resting-state fMRI (rs-fMRI) was shown to be a feasible method for preoperative language assessment. The aim of this study was to examine whether language-related resting-state components, which have been obtained using a data-driven independent-component-based identification algorithm, can be supportive in determining language dominance in the left or right hemisphere.
Methods:
Twenty patients suffering from brain lesions close to supposed language relevant cortical areas were included. Rs-fMRI and task-based (tb-fMRI) were performed for the purpose of preoperative language assessment. Tb-fMRI included a verb generation task with an appropriate control condition (a syllable switching task) to decompose language critical and language supportive processes. Subsequently, the best fitting ICA component for the resting-state language network (RSLN) referential to general linear models (GLMs) of the tb-fMRI (including models with and without linguistic control conditions) was identified using an algorithm based on the Dice-index.
Results:
The RSLNs associated with GLMs using a linguistic control condition led to significantly higher laterality indices than GLM baseline contrasts. LIs derived from GLM contrasts with and without control conditions alone did not differ significantly.
Conclusion:
In general, the results suggest that determining language dominance in the human brain is feasible both with tb-fMRI and rs-fMRI, and in particular, the combination of both approaches yields a higher specificity in preoperative language assessment. Moreover, we can conclude that the choice of the language mapping paradigm is crucial for the mentioned benefits.
Field induced plasticity of magneto-sensitive elastomers for gripping technology applications
(2018)
Bei Zugschwellversuchen kann sowohl die Amplituden- als auch die Mittelspannung frei eingestellt werden. Für eine zusammenfassende Auswertung müssen Amplituden- und Mittelspannungen durch eine einzige sogenannte äquivalente Spannung ersetzt werden. Die Bestimmung dieser äquivalenten Spannung setzt die Kenntnis des sogenannten Mittelspannungseinflusses voraus, der sich von Material zu Material unterscheidet. Aus der Literatur werden die gängigen Modelle zur Beschreibung des Mittelspannungseinflusses bei metallischen Werkstoffen vorgestellt. Daraus werden erstmals geeignete Modelle für Seildrähte abgeleitet. Dadurch lassen sich für Seildrähte die ertragbaren Lastwechselzahlen bei Zugschwellversuchen zuverlässig abschätzen und damit eine allgemeine Beschreibung ihres Materialermüdungsverhaltens angeben.
Einleitung:
Blutdruck gilt als sogenannter Vitalparameter als einer der grundlegenden Indikatoren für den Gesundheitszustand einer Person. Sowohl zu niedriger als auch zu hoher Blutdruck kann lebensbedrohend sein, letzerer ist darüber hinaus ein Risikofaktor insbesondere für Herz-Kreislauferkrankungen, die trotz wichtiger Fortschritte in der Behandlung immer noch die häufigste Todesursache in Deutschland darstellen. Die Hämodynamik, also die raumzeitliche Dynamik des Blutflusses, und der Gefäßzustand sind eng verbunden mit dem Blutdruck und ebenfalls von hoher klinischer Relevanz, u.a. zur Identifikation von Durchblutungsstörungen und ungünstigen Druckverteilungen der Gefäßwand. Innovationen in der Messtechnik als auch in der Datenanalyse bieten heute neue Möglichkeiten der Erfassung und Bewertung von Blutdruck, Hämodynamik und Gefäßzustand [1], [2], [3], [4].
Methodik:
In einer gemeinsamen Workshopserie der AG Medizinische Bild- und Signalverarbeitung der GMDS und des Fachausschusses Biosignale der DGBMT werden wir neue Ansätze und Lösungen für Mess- und Analyseverfahren zu Blutdruck und -fluss sowie zum Gefäßzustand vorstellen und diskutieren. Dabei stehen im ersten Workshop auf der GMDS Jahrestagung Bildbasierte Verfahren im Zentrum, während der zweite Workshop auf der DGBMT Jahrestagung den Fokus auf Biosignalbasierten Verfahren legt. Es werden aktuelle Forschungsergebnisse vorgestellt und diskutiert. Es sind jeweils mehrere Vorträge geplant mit ausreichend Zeit zur Diskussion. Folgende Vorträge sind geplant (Arbeitstitel):
Sebastian Zaunseder: Videobasierte Erfassung des Blutdrucks
Anja Hennemuth: A Visualization Toolkit for the Analysis of Aortic Anatomy and Pressure Distribution
Lars Krenkel: Numerische Analyse der Rupturwahrscheinlichkeit zerebraler Aneurysmata
Susanne Schnell: Messung des Blutflusses und hämodynamischer Parameter mit 4D flow MRI: Möglichkeiten und Herausforderungen
Ergebnisse:
Ziel des Workshops ist die Identifikation von innovativen Ansätzen und neuen Methoden zur qualitativen und quantitativen Bestimmung von hämodynamischen Parametern sowie deren kritische Bewertung durch die Community für die Eignung in der klinischen Entscheidungsunterstützung.
Diskussion:
Der Workshop leistet inhaltlich einen Beitrag zu zentralen Aspekten für die Herz-Kreislauf-Medizin. Er bringt dabei Expertise aus verschiedenen Bereichen zusammen und schlägt die Brücke zwischen Kardiologie, Medizininformatik und Medizintechnik.
Schlussfolgerung:
Innovative Technologien aus Medizintechnik und Informatik ermöglichen zunehmend einfache und raumzeitlich aufgelöste Erfassung und Bewertung wichtiger Informationen zur Unterstützung von Diagnose und Therapieverfolgung.
[1] Zaunseder S, Trumpp A, Wedekind D, Malberg H. Cardiovascular assessment by imaging photoplethysmography - a review. Biomed Tech (Berl). 2018 Oct 25;63(5):617–34.
[2] Huellebrand M, Messroghli D, Tautz L, Kuehne T, Hennemuth A. An extensible software platform for interdisciplinary cardiovascular imaging research. Comput Methods Programs Biomed. 2020 Feb;184:105277.
[3] Schmitter S, Adriany G, Waks M, Moeller S, Aristova M, Vali A, et al. Bilateral Multiband 4D Flow MRI of the Carotid Arteries at 7T. Magn Reson Med. 2020 Oct;84(4):1947–60.
[4] Birkenmaier C, and Krenkel, L. Flow in Artificial Lungs. In: New Results in Numerical and Experimental Fluid Mechanics XIII. Contributions to the 22nd STAB/DGLR Symposium. Springer; 2021.
Tonal components can be regarded as one of the most relevant components for interior sound quality of electric vehicles, especially at low speeds. Sources for these tones are for example the vehicles' drivetrains but also other technical components. Depending on the driving conditions, due to the interaction of various dominant sources, audible tone complexes can occur. Similar to musical intervals, the different frequency ratios within these complexes can result in consonant or dissonant sensations. The strength of this sensation does not only depend on the frequency relation of the tones but also on their relative levels. In this study, different musical intervals were subjectively rated in terms of their specific consonant or dissonant character. Using an adaptive procedure, sound pairs, each consisting of a two-tone signal, where adjusted to equal dissonance by varying the level of the second tone of one of the two-tone signals. Using the same paradigm, also pairs of equal vehicle sound quality were obtained. With these results, it is possible to quantify dissonance, and theinfluence of dissonance on sound quality expressed in terms of level differences of two-tone signals. These results can help to make the concept of dissonance more useful for sound-engineering applications.
With the progress in modern medicine, it was possible to significantly reduce the risks of birth for mother and child. One aspect that has received less attention so far is the risk of injury to the accoucheurs (obstetricians and midwives) during the birth process. Indeed, studies indicate that 92% of midwives suffer from musculoskeletal disorders, with the lower back being the main cause of complaints (72%). The aim of this study was to investigate two commonly used postural techniques used by accoucheurs during childbirth and to analyze the resulting load on the lower back using the AnyBodyTM musculoskeletal simulation software.
Evaluation of muscle recruitment and muscle models in musculoskeletal simulation of dynamic motion
(2021)
Musculoskeletal simulation plays an increasingly important role in sports biomechanics. In the last years, the field of application widened from orthopaedics and ergonomics to sports [1]. A muscle recruitment algorithm with a quadratic objective function is usually used to calculate muscle activity in dynamic movements. The agreement of calculated and measured thigh muscle activity has already been investigated [2]. They found a strong agreement for sprinting and running, while the correlation decreased for side-cutting manoeuvres. Nevertheless, the influence of different muscle recruitment criteria on muscle activity in dynamic musculoskeletal simulations is currently unknown. Hence, this study aimed to analyse the effect of different muscle recruitment criteria and muscle models on the correlation of numerical and measured muscle activity in highly dynamic movements.
FE-Modellbildung der Strahl-Stoff-Wechselwirkung beim Laser-Durchstrahlschweißen in ANSYS 14.0
(2014)
Musculoskeletal modelling of the shoulder – effects on muscle recruitment and joint reaction force
(2019)
The AnyBody™ Modeling System (AMS) [1], is an universally used musculoskeletal simulation software using inverse dynamics. Until now, no complete human hand model is known in the AMS. Also considering other musculoskeletal software platforms, just one detailed entire hand model is recently published [2] but is only based on one subject. The aim of this work is to implement a full detailed hand model for the AMS including all extrinsic and intrinsic muscles using data by the UWB gained through an anatomical study of ten cadaver hands.