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Various fields of science face a reproducibility crisis. For quantum software engineering as an emerging field, it is therefore imminent to focus on proper reproducibility engineering from the start. Yet the provision of reproduction packages is almost universally lacking. Actionable advice on how to build such packages is rare, particularly unfortunate in a field with many contributions from researchers with backgrounds outside computer science. In this article, we argue how to rectify this deficiency by proposing a 1-2-3~approach to reproducibility engineering for quantum software experiments: Using a meta-generation mechanism, we generate DOI-safe, long-term functioning and dependency-free reproduction packages. They are designed to satisfy the requirements of professional and learned societies solely on the basis of project-specific research artefacts (source code, measurement and configuration data), and require little temporal investment by researchers. Our scheme ascertains long-term traceability even when the quantum processor itself is no longer accessible. By drastically lowering the technical bar, we foster the proliferation of reproduction packages in quantum software experiments and ease the inclusion of non-CS researchers entering the field.
Backround
Scaphoidectomy and midcarpal fusion can be performed using traditional fixation methods like K-wires, staples, screws or different dorsal (non)locking arthrodesis systems. The aim of this study is to test the Aptus four corner locking plate and to compare the clinical findings to the data revealed by CT scans and semi-automated segmentation.
Methods:
This is a retrospective review of eleven patients suffering from scapholunate advanced collapse (SLAC) or scaphoid non-union advanced collapse (SNAC) wrist, who received a four corner fusion between August 2011 and July 2014. The clinical evaluation consisted of measuring the range of motion (ROM), strength and pain on a visual analogue scale (VAS). Additionally, the Disabilities of the Arm, Shoulder and Hand (QuickDASH) and the Mayo Wrist Score were assessed. A computerized tomography (CT) of the wrist was obtained six weeks postoperatively. After semi-automated segmentation of the CT scans, the models were post processed and surveyed.
Results
During the six-month follow-up mean range of motion (ROM) of the operated wrist was 60°, consisting of 30° extension and 30° flexion. While pain levels decreased significantly, 54% of grip strength and 89% of pinch strength were preserved compared to the contralateral healthy wrist. Union could be detected in all CT scans of the wrist. While X-ray pictures obtained postoperatively revealed no pathology, two user related technical complications were found through the 3D analysis, which correlated to the clinical outcome.
Conclusion
Due to semi-automated segmentation and 3D analysis it has been proved that the plate design can keep up to the manufacturers’ promises. Over all, this case series confirmed that the plate can compete with the coexisting techniques concerning clinical outcome, union and complication rate.
In this paper we show how a feature-oriented development methodology can be exploited to investigate a large set of possible implementations for a real-time rendering algorithm. We rely on previously published work to explore potential dimensions of the implementation space of an algorithm to be run on a graphics processing unit (GPU) using CUDA. The main contribution of our paper is to provide a clear example of the benefit to be gained from existing methods in a domain that only slowly moves toward higher level abstractions. Our method employs a generative approach and makes heavy use of Common Lisp-macros before the code is ultimately transformed to CUDA.
Parametric surfaces are an essential modeling tool in computer aided design and movie production. Even though their use is well established in industry, generating ray-traced images adds significant cost in time and memory consumption. Ray tracing such surfaces is usually accomplished by subdividing the surfaces on-the-fly, or by conversion to a polygonal representation. However, on-the-fly subdivision is computationally very expensive, whereas polygonal meshes require large amounts of memory. This is a particular problem for parametric surfaces with displacement, where very fine tessellation is required to faithfully represent the shape. Hence, memory restrictions are the major challenge in production rendering. In this paper, we present a novel solution to this problem. We propose a compression scheme for a-priori Bounding Volume Hierarchies (BVHs) on parametric patches, that reduces the data required for the hierarchy by a factor of up to 48. We further propose an approximate evaluation method that does not require leaf geometry, yielding an overall reduction of memory consumption by a factor of 60 over regular BVHs on indexed face sets and by a factor of 16 over established state-of-the-art compression schemes. Alternatively, our compression can simply be applied to a standard BVH while keeping the leaf geometry, resulting in a compression rate of up to 2:1 over current methods. Although decompression generates additional costs during traversal, we can manage very complex scenes even on the memory restrictive GPU at competitive render times.
We present a novel derivative-based parameter identification method to improve the precision at the tool center point of an industrial manipulator. The tool center point is directly considered in the optimization as part of the problem formulation as a key performance indicator. Additionally, our proposed method takes collision avoidance as special nonlinear constraints into account and is therefore suitable for industrial use. The performed numerical experiments show that the optimum experimental designs considering key performance indicators during optimization achieve a significant improvement in comparison to other methods. An improvement in terms of precision at the tool center point of 40% to 44% was achieved in experiments with three KUKA robots and 90 notional manipulator models compared to the heuristic experimental designs chosen by an experimenter as well as 10% to 19% compared to an existing state-of-the-art method.
Jeśli koncepcja sprawiedliwości i równości z uwzględnieniem płci ma zostać włączona do etyki mediów, należy wyjaśnić, jaka koncepcja sprawiedliwości i/lub równości ma zostać zaadaptowana z szerokiego spektrum filozofii politycznej i społecznej. W niektórych teoriach sprawiedliwości pojęcie równości odgrywa ważną rolę, podczas gdy inne zaprzeczają, że sprawiedliwość idzie w parze z równością. W artykule zarysowano tę złożoność i niejednoznaczność, aby pokazać, jak koncepcje sprawiedliwości i równości wpływają na istotne dla płci debaty w mediach i etykę mediów. W tym celu należy jednak ustalić, jakimi dobrami społecznymi należałoby się zająć, jeśli sprawiedliwość i równość miałyby zostać włączone do etyki mediów. W ramach podsumowania należy zauważyć, że włączenie do etyki mediów koncepcji sprawiedliwości i równości z uwzględnieniem płci jako etyki zawodowej dziennikarstwa może prowadzić do zakwestionowania norm i wartości właściwych dla tego zawodu, a tym samym do zakwestionowania samego zawodu.
Moving Object Databases are designed to store and process database objects with attributes that can change over time. Simple examples are moving points, that change position over time, a bit more complex are moving regions, that can also change shape. The spatial and spatiotemporal object types in current moving objects databases are limited to two dimensions. This work strives to extend the set of spatial moving object types into the third and even higher dimensions while preserving a consistent family of operations for it. A robust algorithm for the interpolation of two regions to a moving region of any dimensionality is developed, as well as the fundamental ideas for several other operations.
We address a practical challenge in agile web development against NoSQL data stores: Upon a new release of the web application, entities already persisted in production no longer match the application code. Rather than migrating all legacy entities eagerly (prior to the release) and at the cost of application downtime, lazy data migration is a popular alternative: When a legacy entity is loaded by the application, all pending structural changes are applied. Yet correctly migrating legacy data from several releases back, involving more than one entity at-a-time, is not trivial. In this paper, we propose a holistic Datalog ¬non-rec model model for reading, writing, and migrating data. In implementing our model, we may blend established Datalog evaluation algorithms, such as an incremental evaluation with certain rules evaluated bottom-up, and certain rules evaluated top-down with sideways information passing. Our systematic approach guarantees that from the viewpoint of the application, it remains transparent whether data is migrated eagerly or lazily.
We present a comprehensive analysis of the neural audio-visual synchrony evaluation tool SyncNet. We assess the agreement of SyncNet scores vis-a-vis human perception and whether we can use these as a reliable metric for evaluating audio-visual lip-synchrony in generation tasks with no ground truth reference audio-video pair. We further look into the underlying elements in audio and video which vitally affect synchrony using interpretable explanations from SyncNet predictions and analyse its susceptibility by introducing adversarial noise. SyncNet has been used in numerous papers on visually-grounded text-to-speech for scenarios such as dubbing. We focus on this scenario which features many local asynchronies (something that SyncNet isn’t made for).
Purpose
Age-related macular degeneration (AMD) is a common threat to vision. While classification of disease stages is critical to understanding disease risk and progression, several systems based on color fundus photographs are known. Most of these require in-depth and time-consuming analysis of fundus images. Herein, we present an automated computer-based classification algorithm.
Design Algorithm development for AMD classification based on a large collection of color fundus images. Validation is performed on a cross-sectional, population-based study.
Participants.
We included 120 656 manually graded color fundus images from 3654 Age-Related Eye Disease Study (AREDS) participants. AREDS participants were >55 years of age, and non-AMD sight-threatening diseases were excluded at recruitment. In addition, performance of our algorithm was evaluated in 5555 fundus images from the population-based Kooperative Gesundheitsforschung in der Region Augsburg (KORA; Cooperative Health Research in the Region of Augsburg) study.
Methods.
We defined 13 classes (9 AREDS steps, 3 late AMD stages, and 1 for ungradable images) and trained several convolution deep learning architectures. An ensemble of network architectures improved prediction accuracy. An independent dataset was used to evaluate the performance of our algorithm in a population-based study.
Main Outcome Measures.
κ Statistics and accuracy to evaluate the concordance between predicted and expert human grader classification.
Results.
A network ensemble of 6 different neural net architectures predicted the 13 classes in the AREDS test set with a quadratic weighted κ of 92% (95% confidence interval, 89%–92%) and an overall accuracy of 63.3%. In the independent KORA dataset, images wrongly classified as AMD were mainly the result of a macular reflex observed in young individuals. By restricting the KORA analysis to individuals >55 years of age and prior exclusion of other retinopathies, the weighted and unweighted κ increased to 50% and 63%, respectively. Importantly, the algorithm detected 84.2% of all fundus images with definite signs of early or late AMD. Overall, 94.3% of healthy fundus images were classified correctly.
Conclusions
Our deep learning algoritm revealed a weighted κ outperforming human graders in the AREDS study and is suitable to classify AMD fundus images in other datasets using individuals >55 years of age.