1.9 Chemische und optische Sensorik
Filtern
Dokumenttyp
- Zeitschriftenartikel (23)
- Beitrag zu einem Tagungsband (3)
- Vortrag (3)
- Sonstiges (1)
- Forschungsbericht (1)
Schlagworte
- Fluorescence (10)
- Core-shell particles (6)
- Molecularly imprinted polymers (6)
- Molecular imprinting (5)
- Air quality (3)
- Environment (3)
- Glyphosate (3)
- Microfluidics (3)
- Sialic acid (3)
- Spectroscopy (3)
Organisationseinheit der BAM
- 1 Analytische Chemie; Referenzmaterialien (31)
- 1.9 Chemische und optische Sensorik (31)
- 8 Zerstörungsfreie Prüfung (4)
- 8.1 Sensorik, mess- und prüftechnische Verfahren (4)
- 1.5 Proteinanalytik (3)
- 1.1 Anorganische Spurenanalytik (2)
- 4 Material und Umwelt (2)
- 4.2 Material-Mikrobiom Wechselwirkungen (2)
- 6 Materialchemie (2)
- 6.3 Strukturanalytik (2)
Paper des Monats
- ja (1)
Eingeladener Vortrag
- nein (3)
Fluorescent sensory MIP (molecularly imprinted polymer) particles were combined with a droplet-based 3D microfluidic system for the selective determination of a prototype small-molecule analyte of environmental concern, 2,4-dichlorophenoxyacetic acid or 2,4-D, at nanomolar concentration directly in water samples. A tailor-made fluorescent indicator cross-linker was thus designed that translates the binding event directly into an enhanced fluorescence signal. The phenoxazinone-type cross-linker was co-polymerized into a thin MIP layer grafted from the surface of silica microparticles following a RAFT (reversible addition-fragmentation chain transfer) polymerization protocol. While the indicator cross-linker outperformed its corresponding monomer twin, establishment of a phase-transfer protocol was essential to guarantee that the hydrogen bond-mediated signalling mechanism between the urea binding site on the indicator cross-linker and the carboxylate group of the analyte was still operative upon real sample analysis. The latter was achieved by integration of the fluorescent core-shell MIP sensor particles into a modular microfluidic platform that allows for an in-line phasetransfer assay, extracting the analyte from aqueous sample droplets into the organic phase that contains the sensor particles. Real-time fluorescence determination of 2,4-D down to 20 nM was realized with the system and applied for the analysis of various surface water samples collected from different parts of the world.