Filtern
Dokumenttyp
Schlagworte
- Bioinformatics (2)
- Virology (2)
- Beton (1)
- Bioinformatics virology viruses software (1)
- NDT-CE (1)
- Qualitätssicherung (1)
- SAFT (1)
- Software (1)
- Ultraschall-Echo (1)
- Ultrasonic echo (1)
Organisationseinheit der BAM
Virologists. You might know a couple of them, but unless you are a virologist yourself, the probability that you have collaborated with one in the past is low. The community is relatively small, but they pack a heavy punch and are expected to play a leading role in the research into pathogens that lies ahead. You may ask why we think virologists are our future. Suffice it to say that it is not just because they have invented technologies that belong to the space age, including use of viruses as vehicles to shuttle genes into cells[1], organic nanoparticles with specific tools attached to their surfaces to get inside target cells[2], and using genetically modified viruses as therapies to fight against cancer[3]. Did you know that virologists currently only know of about 3,200 viral species but that more than 320,000 mammal-associated viruses[4] are thought to await discovery? Just think about the viruses hidden in the Arctic ice[5] or in the insects and other animals from once cut-off regions in the world, which now face ever-increasing human exposure[6]. But a heroic (as well as an apocalyptic) role for virologists may also be on the horizon, as the adoption of phage therapy may, in the future, be used to control harmful bacteria when antibiotics fail
Despite the recognized excellence of virology and bioinformatics, these two communities have interacted surprisingly sporadically, aside from some pioneering work on HIV-1 and influenza. Bringing together the Expertise of bioinformaticians and virologists is crucial, since very specific but fundamental computational approaches are required for virus research, particularly in an era of big data. Collaboration between virologists and bioinformaticians is necessary to improve existing analytical tools, cloud-based systems, computational resources, data sharing approaches, new diagnostic tools, and bioinformatic training. Here, we highlight current progress and discuss potential avenues for future developments in this promising era of virus bioinformatics. We end by presenting an overview of current technologies, and by outlining some of the Major challenges and Advantages that bioinformatics will bring to the field of virology.
Bioinformatics meets virology: The European virus bioinformatics center's second annual meeting
(2018)
The Second Annual Meeting of the European Virus Bioinformatics Center (EVBC), held in Utrecht, Netherlands, focused on computational approaches in virology, with topics including (but not limited to) virus discovery, diagnostics, (meta-)genomics, modeling, epidemiology, molecular structure, evolution, and viral ecology. The goals of the Second Annual Meeting were threefold: (i) to bring together virologists and bioinformaticians from across the academic, industrial, professional, and training sectors to share best practice; (ii) to provide a meaningful and interactive scientific environment to promote discussion and collaboration between students, postdoctoral fellows, and both new and established investigators; (iii) to inspire and suggest new research directions and questions. Approximately 120 researchers from around the world attended the Second Annual Meeting of the EVBC this year, including 15 renowned international speakers. This report presents an overview of new developments and novel research findings that emerged during the meeting.
Ultrasonic imaging systems usually require an array of ultrasonic transducers for data acquisition on a wide area on top of an object under investigation. The goal of an imaging algorithm is the use of reflected ultrasound data to form a recognizable image. Conventional algorithms like SAFT are based on an inverse Huygens' principle and need therefore a dense measurement grid. This requires a big effort in data capturing. For simple and inexpensive measurement different strategies of imaging with reduced amount of data and examples with a manual scanning device on concrete elements are presented.
Der Fachbereich 8.2 der Bundesanstalt für Materialforschung und -prüfung (BAM) hat eine innovative Methode zur zerstörungsfreien Ultraschallprüfung erarbeitet und den technischen Aufbau in Form eines neuen Gerätes entwickelt. Mit Hilfe des Produktdesigns soll die Etablierung auf dem Markt sichergestellt werden.
Die Arbeit erläutert detailliert die Bereiche, die für die Gestaltung des Handscangerätes von Bedeutung sind. Sie befasst sich mit der Installation und Handhabung des Systems am Einsatzort und beleuchtet wichtige technische Details. Der nicht verkleidete technische Aufbau der zwei neu entwickelten Geräte dient als Grundlage für die Erarbeitung eines Gehäusekonzepts. Neben dem Gehäusedesign wird eine Überarbeitung des gesamten Aufbaus durchgeführt, um die Benutzerfreundlichkeit in verschiedenen Punkten zu verbessern. Zukünftige Designentscheidungen werden auf Grundlage von praxisnahen Beobachtungen und der notwendigen Anordnung der technischen Komponenten getroffen. Ziel der Auseinandersetzung ist es, ein funktionelles und ästhetisch ansprechendes Design zu entwickeln. Am Ende sollen unter Beachtung aller Vorgaben die Ergebnisse dieser Arbeit zu einem ergonomischen Gerät führen.
Die Problemstellung besteht daraus, den komplexen technischen Vorgaben und Ansprüchen des Projektpartners und Innovationsgebers gerecht zu werden und gleichzeitig ein gutes Designziel zu erreichen. Das Design soll die Funktionalität und Handhabung des Gerätes verbessern und dient als Hilfsmittel, um den komplexen Aufbau zu vereinfachen. Die Benutzerfreundlichkeit soll an allen nötigen Stellen verbessert werden und ein ästhetisch zusammenstehender Gesamteindruck soll entstehen, ohne die Funktionalität negativ zu beeinflussen.