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Paper des Monats
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We present the instrumentation of the newly constructed prestressed concrete bridge BW2 along the A117 motorway, located at the southeastern border between Berlin and Brandenburg, using distributed fiber optic sensing. The fiber optic sensors were embedded into all major components of the bridge structure, including the deck slab, abutments, and all precast girders. The fiber optic sensing cables were designed to allow flexible configuration of measurement sections. During the construction phase, verification measurements and a load test were performed to evaluate installation quality, sensor performance, and data reliability. The results demonstrate that distributed fiber optic sensing is an effective and practical technology for structural health monitoring of new bridge constructions and can represent a key enabler for predictive maintenance management.
With growing interest in electrochemical processes in supporting a future low-carbon energy and chemical manufacturing infrastructure, modeling studies have surged. To provide structure to the expanding body of work, we present a review of the major electrolysis technologies and their modeling trends. Modeling efforts across the technologies are largely siloed, with each community employing different approaches and levels of rigor for varying modeling objectives. While the differences stem partly from the distinct phenomena involved, they are also due to limited exchange within a broader community. By comparing modeling practices for specific goals, e.g., models for design, operation, or start-up, we identify research gaps and opportunities for shared learning. Focusing on water electrolysis as well as the chlor-alkali process, we assess which practices should be continued, improved, or adopted to ultimately improve the fidelity and predictive capability of electrolytic process models.
Immuno-detection biosensors represent a well-established and widely recognised class of analytical tools. The popularity of these devices can be attributed to their exceptional selectivity and impressive sensitivity. However, when trace-level detection is required — particularly for small molecules — sensitivity can become a limiting factor. This challenge evident in fields such as forensic analysis, where the in-situ detection of explosives remains difficult due to the scarcity of highly sensitive sensor platforms.
In this work, an optical biosensor designed for the highly specific and sensitive detection of HomeMade Explosives (HME) is introduced. The immunoassay is embedded within a hydrogel matrix that is both permeable to the analyte and optically transparent, thereby enabling interrogation of fluorescently labeled antibodies. The signal readout is achieved using Supercritical Angle Fluorescence (SAF), an advanced microscopy technique that enhances surface-level fluorescence detection while suppressing bulk emission. In order to implement SAF, a parabolic optical geometry is required. The use of a high-resolution SLA printer (with a resolution of less than 22 µm) allowed us to fabricate this tailored optical element. Prior to the fabrication stage, optical simulations were conducted to validate the light path for
optimal SAF collection. Additionally, to study the optical suitability of the material used, a
spectroscopic and physical characterisation was conducted. This cost-effective approach,
characterised by rapid production and minimal design constraints, was specifically engineered to capture emission at the immunoanalytical interface. In order to facilitate antibody-specific recognition, the glass surface was functionalised with a hapten corresponding to the target analyte, thereby enabling non-covalent attachment of labelled antibodies. This configuration permits antibody displacement and, consequently, SAF signal modulation (see Figure 1). The integration of immunoanalytical recognition with SAF detection has resulted in a platform that exhibits modularity and versatility. This development signifies the potential for the advancement of next-generation sensors capable of trace-level detection and substance
identification.
In this paper, we use distributed fiber optic sensing (DFOS) for traffic load monitoring on a newly constructed bridge equipped with a network of embedded optical fibers. Specifically, the optical fibers are embedded longitudinally in all bridge girders at two depths, forming a looped sensing configuration that enables the measurement of different stress states when a vehicle passes. The measurements presented here were conducted before the bridge was opened to traffic, using a mobile crane weighing approximately 36 metric tons, with the load distributed evenly across three axles. We show that our DFOS system can effectively capture the bridge structural response to the moving mobile crane and provide estimates of axle weight distribution and spacing. Finally, the results indicate that, although the fibers located in the girders beneath the loaded lane are strongly affected by the traffic, the fibers beneath the unloaded lane show only a negligible response, highlighting the ability to separate the effects of vehicles traveling in neighboring lanes.
In the SimuCrown project, ageing mechanisms within the crown-cement-tooth complex (CCTC) are investigated, with a focus on high-resolution structural characterisation. Although dental crowns are widely used indirect restorations worldwide, links between clinical complications such as debonding, fractures and time-dependent cement degradation remain insufficiently understood. To address this, we employ high-resolution X-ray µCT and synchrotron X-ray refraction radiography (SXRR) to identify microstructural ageing processes which are inaccessible with conventional imaging.
CCTCs subjected to controlled chewing simulation are examined using SXRR to detect structural alterations, interfacial defects, and the progression of damage within the cement layer and neighbouring materials. Our research explores crack initiation, pore evolution, and interfacial integrity using SXRR, capturing degradation phenomena across multiple time scales. By integrating synchrotron imaging with functional ageing simulation and computational modelling, the SimuCrown project offers a robust framework for evaluating the long-term performance of dental restorations. The outcomes contribute to the optimisation of materials and cementation approaches aimed at improving the clinical durability of dental restorations.
Multiple sclerosis is an autoimmune-mediated neurodegenerative disease of the central nervous system and is characterized by physical disability, cognitive impairment, and other symptoms. Gadolinium-enhanced magnetic resonance imaging is the most common tool for diagnosing multiple sclerosis and monitoring treatment. Numerous studies in recent years suggest that linear gadolinium-based contrast agents (GBCAs) in particular accumulate in various body tissues, including the brain. In our study, we investigated whether neuroinflammation promotes Gd deposition in the brain after repeated administration of linear and macrocyclic GBCAs. For this purpose, the experimental autoimmune encephalomyelitis (EAE) mouse model frequently used for studies on multiple sclerosis was employed. Healthy control mice (HC) and EAE mice were injected with GBCAs at different time points. On day 1, 10 or 40 after the last GBCA administration, the mice were sacrificed and cryosections were prepared from different brain regions. A laser ablation system coupled to an inductively coupled plasma time-of-flight mass spectrometer (LA-ICP-ToF-MS) was used for elemental mapping. Gd was detected in both HC and EAE mice, however EAE brains showed significantly higher Gd levels compared to HC. Inflammation thus promotes long-term retention after GBCA administration.
Emulsion explosives based on ammonium nitrate are an easy-to-use explosive mainly used for mining. In principle, the ammonium nitrate emulsion can be sensitized by various methods like gassing or the addition of microballoons. The introduction of these hot-spots is important for an adiabatic compression and subsequent detonative propagation. This technique is reliable even at colder temperatures. Now, experiments in a rectangular test setup have shown that the size and composition of the sensitizing material indeed have an impact on the detonation ability of the emulsion explosive. This happens to an extent of a full detonation at 20°C and a failure at 0°C. Whereas, usually the ambient temperature does not have an influence on an effective detonation. Different calorimetric methods like DSC and MMC, as well as practical detonation tests and the UN-Test F.3 (BAM Trauzl Test) have been used to examine the behavior of emulsion explosives.
The recent coupling of electrospray ionization (ESI) with acoustic ion manipulation (AIM) has expanded the range of ionic species that can be successfully controlled with an acoustic field. The use of a drying tube was critical to this process to ensure sufficient desolvation and enable the strongest AIM interaction. Here, we explore how desolvation of small-molecule and protein ions impacts the AIM process in more detail. Specifically, acoustic gating of ions from ubiquitin, cytochrome c, and a standard mass calibration mixture was studied for drying tube temperatures from 30 to 210 °C. Transmission of an ion beam trajectory through an acoustic antinode has been previously established as a reliable and simple measure for the acoustic-ion interaction cross section. The transmission of different charge states of protein ions was found to be heavily temperature dependent. This unique observation enabled exploration of the potential impact of different ESI mechanisms on the availability of ions for AIM interactions. The behaviors of singly charged and multiply charged ions traversing a standing acoustic wave were compared and suggest that the electrostatic properties, as well as the resulting higher-order structure, of ions at least partially explain AIM behaviors. Additionally, the increased desolvation temperature led to ion transmission values consistent with dry, plasma-produced ions (i.e., less than 5%) across all species tested. The use of a higher drying temperature ultimately further optimized ESI-AIM, as well as highlighted the role of ion properties during the AIM phenomenon.
Manipulation of Electrospray-Produced Biomolecular Ions with Acoustic Fields at Atmospheric Pressure
(2026)
The coupling of electrospray ionization (ESI) with the newly discovered acoustic ion manipulation (AIM) phenomenon is demonstrated for biopolymeric ions, including peptides, proteins, and oligonucleotides. It is shown that large(i.e.,up to ca.29 kDa) and multiply charged Ions are influenced by the presence of acoustic fields. Specifically, we demonstrate the ability to gate, modulate, redirect, and focus These biomolecular Ions with an acoustic field. To ensure effective acoustic control of ESI-generated ions, it was necessary to desolvate the electrospray droplets and ions prior to the AIM field through optimization of drying tube temperature and spray gas pressure. In general, small and highly charged Ions were more readily deflected from the unstable antinode Region toward the acoustic nodes.This trend Extended to acharge-state-dependent behavior for proteinions, where higher-charge Ions of the same molecule werere directed more easily than their lower-charge counterparts. This work laysa foundation for the implementation of AIMin the study of biomolecules aswell as other analytes introducedbyESI to ion-based spectroscopic techniques, such as massspectrometry and ion mobility spectrometry.
Hyper- and Multispectral Thermography for Quantitative in-process Temperature Mapping in Metal AM
(2026)
Accurate temperature mapping in and around the melt pool is key for material and process qualification in metal AM. It enables optimization of advanced strategies like beam shaping and may serve as a high-level in-situ standard for sensor calibration and process control. Rather than defining machine-dependent process windows, material-dependent (or even independent) thermal metrics for stable processes may become feasible once they are reproducibly measurable.We present a process-integrated approach using hyperspectral high-speed thermography in the short-wave infrared (SWIR) range for PBF-LB/M and multispectral thermography in the mid-wave infrared (MWIR) range for DED-LB/M. Temperature and spectral emissivity maps are reconstructed simultaneously via temperature–emissivity separation, while uncertainty is quantified through reconstruction residuals. Among others, the method is experimentally validated under real process conditions by correct reconstruction of solidification temperatures.
By providing reliable in-process thermal data, this approach supports advanced control strategies and accelerates qualification in industrial metal AM.