Computing D-optimal experimental designs for estimating treatment contrasts under the presence of a nuisance time trend
- We prove a mathematical programming characterisation of approximate partial D-optimality under general linear constraints. We use this characterisation with a branch-and-bound method to compute a list of all exact D-optimal designs for estimating a pair of treatment contrasts in the presence of a nuisance time trend up to the size of 24 consecutive trials.
Author: | Radoslav Harman, Guillaume Sagnol |
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Editor: | Ansgar Steland, Ewaryst Rafajłowicz, Krzysztof Szajowski |
Document Type: | In Proceedings |
Parent Title (English): | Stochastic Models, Statistics and Their Applications |
Volume: | 122 |
First Page: | 83 |
Last Page: | 91 |
Series: | Springer Proceedings in Mathematics & Statistics |
Publisher: | Springer |
Year of first publication: | 2015 |
Preprint: | urn:nbn:de:0297-zib-53640 |
DOI: | https://doi.org/10.1007/978-3-319-13881-7_10 |