TY - CONF A1 - Harman, Radoslav A1 - Sagnol, Guillaume A2 - Steland, Ansgar A2 - Rafajłowicz, Ewaryst A2 - Szajowski, Krzysztof T1 - Computing D-optimal experimental designs for estimating treatment contrasts under the presence of a nuisance time trend T2 - Stochastic Models, Statistics and Their Applications N2 - We prove a mathematical programming characterisation of approximate partial D-optimality under general linear constraints. We use this characterisation with a branch-and-bound method to compute a list of all exact D-optimal designs for estimating a pair of treatment contrasts in the presence of a nuisance time trend up to the size of 24 consecutive trials. Y1 - 2015 UR - https://opus4.kobv.de/opus4-zib/frontdoor/index/index/docId/5365 VL - 122 SP - 83 EP - 91 PB - Springer ER -