Magnetic Resonance Imaging and Computational Fluid Dynamics of High Frequency Oscillatory Ventilation (HFOV)
- In order to better understand the mechanisms of gas transport during High Frequency Oscillatory Ventilation (HFOV) Magnetic Resonance Imaging (MRI) with contrast gases and numerical flow simulations based on Computational Fluid Dynamics(CFD) methods are performed. Validation of these new techniques is conducted by comparing the results obtained with simplified models of the trachea and a first lung bifurcation as well as in a cast model of the upper central airways with results achieved from conventional fluid mechanical measurement techniques like e.g. Laser Doppler Anemometry (LDA). Further it is demonstrated that MRI of experimental HFOV is feasible and that Hyperpolarized 3He allows for imaging the gas re-distribution inside the lung. Finally, numerical results of oscillatory flow in a 3rd generation model of the lung as well as the impact of endotracheal tubes on the flow regime development in a trachea model are presented.
Author: | Alexander-Wigbert K. Scholz, Lars KrenkelORCiDGND, Maxim Terekhov, Janet Friedrich, Julien Rivoire, Rainer Köbrich, Ursula Wolf, Daniel Kalthoff, Matthias David, Claus Wagner, Laura Maria Schreiber |
---|---|
DOI: | https://doi.org/10.1007/978-3-642-20326-8_7 |
ISBN: | 978-3-642-20325-1 |
Parent Title (English): | Fundamental Medical and Engineering Investigations on Protective Artificial Respiration |
Publisher: | Springer |
Place of publication: | Berlin, Heidelberg |
Editor: | Ernst Heinrich Hirschel, Wolfgang Schröder, Kozo Fujii, Werner Haase, Bram Leer, Michael A. Leschziner, Maurizio Pandolfi, Jacques Periaux, Arthur Rizzi, Bernard Roux, Yurii I. Shokin, Michael Klaas, Edmund Koch, Wolfgang Schröder |
Document Type: | Part of a Book |
Language: | English |
Year of first Publication: | 2011 |
Release Date: | 2022/12/10 |
Tag: | Central Airway; Computational Fluid Dynamics Simulation; Laser Doppler Anemometry; Magnetic Resonance Imaging Measurement; computational fluid dynamics |
Volume: | 116 |
First Page: | 107 |
Last Page: | 128 |
Andere Schriftenreihe: | Notes on Numerical Fluid Mechanics and Multidisciplinary Design ; 116 |
Institutes: | Fakultät Maschinenbau |
Fakultät Maschinenbau / Labor Biofluidmechanik | |
Publication: | Externe Publikationen |
research focus: | Digitalisierung |
Licence (German): | Keine Lizenz - Es gilt das deutsche Urheberrecht: § 53 UrhG |