92C50 Medical applications (general)
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- Laser treatment (1)
- bio-heat equation (1)
- cancer therapy (1)
- coagulation (1)
- cow (1)
- differential equations (1)
- hormone patterns (1)
- reproduction (1)
- systems biology (1)
Our model of the bovine estrous cycle is a set of ordinary differential equations which generates hormone profiles of successive estrous cycles with several follicular waves per cycle. It describes the growth and decay of the follicles and the corpus luteum, as well as the change of the key substances over time. In this work we describe recent improvements of this model, including the introduction of new components, and elimination of time delays. We validate our model by showing that the simulations agree with observations from synchronization studies and with measured progesterone data after a single dose administration of synthetic prostaglandin F2alpha.
We study a mathematical model for laser-induced thermotherapy,
a minimally invasive cancer treatment. The model consists of a
diffusion approximation of the radiation transport equation
coupled to a bio-heat equation and a model to describe the
evolution of the coagulated zone. Special emphasis is laid on
a refined model of the applicator device, accounting for the
effect of coolant flow inside. Comparisons between experiment
and simulations show that the model is able to predict the
experimentally achieved temperatures reasonably well.