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How do gravity alterations affect animal and human systems at a cellular/tissue level?

  • The present white paper concerns the indications and recommendations of the SciSpacE Science Community to make progress in filling the gaps of knowledge that prevent us from answering the question: “How Do Gravity Alterations Affect Animal and Human Systems at a Cellular/Tissue Level?” This is one of the five major scientific issues of the ESA roadmap “Biology in Space and Analogue Environments”. Despite the many studies conducted so far on spaceflight adaptation mechanisms and related pathophysiological alterations observed in astronauts, we are not yet able to elaborate a synthetic integrated model of the many changes occurring at different system and functional levels. Consequently, it is difficult to develop credible models for predicting long-term consequences of human adaptation to the space environment, as well as to implement medical support plans for long-term missions and a strategy for preventing the possible health risks due to prolonged exposure to spaceflight beyond the low Earth orbit (LEO). The research activities suggested by the scientific community have the aim to overcome these problems by striving to connect biological and physiological aspects in a more holistic view of space adaptation effects.

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Author:Monica Monici, Christiane Thielemann
DOI:https://doi.org/https://doi.org/10.1038/s41526-023-00330-y
Parent Title (English):nature npj Microgravity
Document Type:Article
Language:English
Year of Completion:2023
Date of first Publication:2023/10/21
Release Date:2023/12/13
GND Keyword:Raumfahrt; Schwere; Raumfahrtbiologie
Volume:2023
Issue:9/84
First Page:1
Last Page:9
Note:
Artikel hat 62 Autoren
Urheberrecht:0
Institutes:Fakultät Ingenieurwissenschaften / Labore / BIOMEMS Lab
research focus :Materials / Material Testing & Sensor Technology
Licence (German):Creative Commons - CC BY-NC - Namensnennung - Nicht kommerziell 4.0 International
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