Wissenschaftliche Artikel der BAM
Filtern
Dokumenttyp
- Zeitschriftenartikel (347)
- Sonstiges (6)
- Beitrag zu einem Tagungsband (1)
- Corrigendum (1)
Sprache
- Englisch (345)
- Deutsch (9)
- Mehrsprachig (1)
Schlagworte
- Fluorescence (52)
- Quantum yield (35)
- Sensor (24)
- Lifetime (21)
- Quality assurance (20)
- Dye (18)
- Photophysics (18)
- Nano (16)
- Synthesis (13)
- Immunoassay (12)
- Magnetic resonance imaging (12)
- NIR (12)
- Photoluminescence (12)
- Cancer (11)
- Imaging (11)
- Lanthanide (10)
- Nanomaterial (10)
- Nanoparticle (10)
- Method (9)
- Nanoparticles (9)
- Particle (9)
- Quantum dots (9)
- ELISA (8)
- Electrochemistry (8)
- ICP-MS (8)
- Mechanism (8)
- Molecularly imprinted polymers (8)
- Reference material (8)
- Energy transfer (7)
- Mass spectrometry (7)
- Raman spectroscopy (7)
- Soil (7)
- Traceability (7)
- Affinity chromatography (6)
- Contrast agent (6)
- Gadolinium (6)
- Luminescence (6)
- MRI (6)
- Mass Spectrometry (6)
- Multiplexing (6)
- Mycotoxins (6)
- Optical probe (6)
- PH (6)
- Surface chemistry (6)
- Upconversion nanoparticle (6)
- Core-shell particles (5)
- Cr(III) (5)
- Flow cytometry (5)
- IgG (5)
- Laser ablation (5)
- Ligand (5)
- Microscopy (5)
- Raman microspectroscopy (5)
- Reproducibility (5)
- Single particle (5)
- Aggregation (4)
- Analytical Chemistry (4)
- Biosensor (4)
- Brightness (4)
- Cement (4)
- HPLC (4)
- Immunosensor (4)
- Industry 4.0 (4)
- Interlaboratory comparison (4)
- LA-ICP-MS (4)
- LC-MS/MS (4)
- LIBS (4)
- Lab-on-a-chip (4)
- Metabolomics (4)
- Nitrotyrosine (4)
- Polymer (4)
- Protein A (4)
- Quantitative spectroscopy (4)
- SWIR (4)
- Signal enhancement (4)
- XPS (4)
- XRF (4)
- Air pollution (3)
- Allergy (3)
- Antibiotics (3)
- Antibodies (3)
- Antikörper (3)
- BODIPY (3)
- Bead (3)
- Biosensing (3)
- Bisphenol A (3)
- Brain (3)
- Calibration (3)
- Coating (3)
- Complex (3)
- Copper (3)
- Corrosion (3)
- Crystal (3)
- DNA origami (3)
- Diagnostics (3)
- Ergot alkaloids (3)
- Excitation power density (3)
- Extracellular matrix (3)
- FPLC (3)
- Food (3)
- Food analysis (3)
- Gadofosveset (3)
- Gas chromatography (3)
- General Medicine (3)
- HRMS (3)
- High-resolution mass spectrometry (3)
- Human serum (3)
- Hybridoma (3)
- Hydrolysis (3)
- Immunocapture (3)
- Immunoglobulins (3)
- Iron oxide (3)
- Isotope dilution (3)
- Isotope ratio (3)
- MOF (3)
- Mass Spectroscopy (3)
- Mechanochemistry (3)
- Metrology (3)
- Microfluidics (3)
- Molecular imaging (3)
- Molecular imprinting (3)
- Monoclonal antibody (3)
- Mycotoxin (3)
- NMR (3)
- Nitration (3)
- Optical spectroscopy (3)
- Pollution (3)
- Process Industry (3)
- Protein G (3)
- Quality Control (3)
- Quantification (3)
- Raman (3)
- Reference materials (3)
- Screening (3)
- Sensitization (3)
- Spectroscopy (3)
- Switch (3)
- Teststreifen (3)
- Transformation products (3)
- Tyrosine (3)
- Uncertainty (3)
- Upconversion (3)
- AAS (2)
- Absolute isotope ratio (2)
- Affinity Chromatography (2)
- Affinitätschromatographie (2)
- Aggregation induced emission (2)
- Amorphous carbon (2)
- Amoxicillin (2)
- Amperometry (2)
- Antibody (2)
- Antibody coating (2)
- Aromatic amino acid analysis (2)
- Atherosclerosis (2)
- Bacteria (2)
- Barcoding (2)
- Bead-based assay (2)
- Benz[a]anthracene (BaA) (2)
- Benzo[a]pyrene (BaP) (2)
- Biochemistry (2)
- Biochip (2)
- Biocides (2)
- Bioconjugation (2)
- CONSENS (2)
- Cell proliferation (2)
- Certified reference material (2)
- Charge transfer (2)
- Chromatography (2)
- Comparability (2)
- Core−shell particles (2)
- Cuprorivaite (2)
- Cytotoxicity (2)
- Delta scale (2)
- Derivatization (2)
- Diagnosis (2)
- Digitalisation (2)
- Dimerization (2)
- Dityrosine (2)
- Documentation (2)
- Egyptian blue (2)
- Electron microscopy (2)
- Emission spectroscopy (2)
- Endocrine disruptor (2)
- Enhancement (2)
- Environmental Chemistry (2)
- Exocytosis (2)
- Fatty acid metabolism (2)
- Fertilizer (2)
- Ferumoxytol (2)
- Fluoride (2)
- Gas chromatography (GC) (2)
- General Earth and Planetary Sciences (2)
- Glyphosate (2)
- Gold nanoparticles (2)
- HPLC-MS/MS (2)
- HTS (2)
- Health, Toxicology and Mutagenesis (2)
- Heart failure (2)
- Hydrazinolysis (2)
- ICP-OES (2)
- Immunoaffinity extraction (2)
- Immunoprecipitation (2)
- Indium phosphide (2)
- Indoor air (2)
- Inflammation (2)
- Iron (2)
- Isotope (2)
- Isotope dilution (ID) (2)
- Isotope ratios (2)
- LIF (2)
- Label (2)
- Lanthanides (2)
- Lateral flow assay (2)
- Life sciences (2)
- Limit of detection (2)
- Lipidomic profile (2)
- Liquid chromatography (LC) (2)
- Lithium (2)
- MALDI (2)
- MALDI-TOF MS (2)
- MC-ICP-MS (2)
- Magnetic beads (2)
- Mass spectrometry (MS) (2)
- Measurement uncertainty (2)
- Mercury (2)
- Mesoporous materials (2)
- Metabolic stress (2)
- Method development (2)
- Microarray (2)
- Microbeads (2)
- Mikrofluidik (2)
- Mikroplastik (2)
- Modelling (2)
- Modular Production (2)
- Molecularly Imprinted Polymers (2)
- Monoclonal Antibodies (2)
- Monolithic column (2)
- Multiplex (2)
- Nanomaterials (2)
- Nickel (2)
- Nitrogen oxides (2)
- Nontarget analysis (2)
- Open Science (2)
- Optical detection (2)
- Origami (2)
- Oxygen (2)
- Ozone (2)
- PFAS (2)
- Passivation (2)
- Peptide (2)
- Peptide library (2)
- Phenylalanine (2)
- Phosphorylated peptides (2)
- Photodegradation (2)
- Polycyclic aromatic hydrocarbon (PAH) (2)
- Probe (2)
- Process Analytical Technology (2)
- Process analytical technology (2)
- Production (2)
- Prostate cancer (2)
- Protein (2)
- Protein nitration (2)
- Proximity-enhanced reaction (2)
- Purification (2)
- Quantum dot (2)
- Real-time process monitoring (2)
- Regeneration (2)
- Sapphire (2)
- Self-assembly (2)
- Sensorpartikel (2)
- Sensors (2)
- Sequence coverage (2)
- Serum (2)
- Sewage sludge (2)
- Shell (2)
- Sialic acid (2)
- Single molecule (2)
- Smart sensors (2)
- Software (2)
- Solid state NMR (2)
- Sr isotopes (2)
- Standardization (2)
- Standards (2)
- Surface (2)
- Sythesis (2)
- Test strips (2)
- Theory (2)
- Thermal anhydrite (2)
- Thermal desorption (2)
- Toxicity (2)
- Transformation product (2)
- Triple isotope fractionation (2)
- Triplet-triplet annihilation (2)
- Tumor (2)
- Tumor metabolism (2)
- Ultrafine particles (2)
- Upconversion nanoparticles (2)
- Uptake studies (2)
- Validation (2)
- Water analysis (2)
- Yb(III) complex (2)
- ZIF (2)
- ZIF-8 (2)
- 1-indanol (1)
- 150th anniversary (1)
- 150th anniversary of BAM (1)
- 2,5-dihydroxyacetophenone (1)
- 280 nm (1)
- 2D chromatography (1)
- 3D-Mikrofluidik (1)
- 6xHis (1)
- AAA (1)
- AAAA (1)
- ABC (1)
- ABID (1)
- AF4 (1)
- AIE (1)
- AIS (1)
- ATCUN (1)
- Aautomatisation (1)
- Absorption (1)
- Abwasser (1)
- Acoustic (1)
- Acoustic resonance (1)
- Acrylamide (1)
- Acute myocardial infarction (1)
- Additive Fertigung (1)
- Additive Manufacturing (1)
- Additive manufacturing (1)
- Adsorbable organically bound fluorine (AOF) (1)
- Adsorption (1)
- Adulteration (1)
- Advanced Materials (1)
- Advanced material (1)
- Advanced materials (1)
- Advanced nanomaterials (1)
- Affinity (1)
- Affinity Extraction (1)
- Affinity Separation (1)
- Affinity extraction (1)
- Affinitätsextraktion (1)
- AgInS (1)
- Agarose (1)
- Aggregates (1)
- Aggregation-induced emission (1)
- Aging (1)
- Agriculture (1)
- Air filter samples (1)
- Air particulate matter (1)
- Air sampling (1)
- Airport (1)
- AlCl (1)
- Alanine scan (1)
- Algorithms (1)
- Altenuene (1)
- Alternaria mycotoxins (1)
- Aluminum (1)
- Aluminum oxide (1)
- Alzheimer’s disease (1)
- Amino acid analysis (1)
- Amplification (1)
- Amyloid-beta (1)
- Analysis (1)
- Analytical methods (1)
- Analytical sciences (1)
- Aneurysm (1)
- Angiography (1)
- Angiotensin II (1)
- Anhydrite (1)
- Aniline (1)
- Animal slurry (1)
- Anion recognition (1)
- Antagonists (1)
- Anthropocene (1)
- Antibody Purification (1)
- Antibody identification (1)
- Antibody-gated indicator delivery (1)
- Antifouling surface (1)
- Antigens (1)
- Antimicrobial resistance (1)
- App (1)
- Application (1)
- Aptamere (1)
- Aqueous quantum dot (1)
- Aqueous synthesis (1)
- Arabidopsis (1)
- Argon (1)
- Array (1)
- Arsenite (1)
- Artificial Neural Networks (1)
- Artificial intelligence (1)
- Artificial neural networks (1)
- Artificial weathering (1)
- Ash content (1)
- Aspergillus (1)
- Assay (1)
- Atherosclerotic plaques (1)
- Atmospheric aerosol (1)
- Atomic Absorption Spectrometry (1)
- Atomic absorption spectrometry (1)
- Atomic and molecular physics, and optics (1)
- Atomic force microscopy (1)
- Atomic weight (1)
- Augenbohne (1)
- Autoantibodies (1)
- Automated Purification (1)
- Automated image analysis (1)
- Automation (1)
- Autophagy (1)
- Aviation (1)
- Aza-BODIPY (1)
- BAM (1)
- BCA test (1)
- BODIPY dyes (1)
- BODIPY probe (1)
- BODIPYs (1)
- BPA removal (1)
- Back-side integration (1)
- Bacterial lipopolysaccharides (1)
- Bacterial lysates (1)
- Ball milling (1)
- Bassanite (1)
- Bead injections (1)
- Benchmarking study (1)
- Benchtop NMR (1)
- Benzene-1,3,5-tricarboxylic acid (1)
- Benzin (1)
- Benzothiadiazole (1)
- Benzoxadiazole dyes (1)
- Beschichtung (1)
- Bet v 1 (1)
- Betula pendula (1)
- Binary gas mixture (1)
- Binder (1)
- Binding molecule (1)
- Bioanalysis (1)
- Biodiesel (1)
- Biodiesel fuel (1)
- Biofilm (1)
- Bioinformatics (1)
- Biology (1)
- Biomarker (1)
- Biomarkers (1)
- Biomimicry (1)
- Biosensors (1)
- Bioseparation (1)
- Biosilicification (1)
- Biosynthesis (1)
- Biotechnology (1)
- Biotests (1)
- Birch pollen allergen (1)
- Bismuth (1)
- Boden (1)
- Boltzmann plot (1)
- Bombs (1)
- Border surveillance (1)
- Boron compound (1)
- Borosilicate Glass (1)
- Borosilicatglas (1)
- Borosilikatglas (1)
- Bovine serum albumin (BSA) (1)
- Bradford (1)
- Building material (1)
- Bundesanstalt für Materialforschung und -prüfung (1)
- C-C coupling (1)
- CCQM (1)
- CE/MC-ICP-MS (1)
- CEA (1)
- CO2 + n-alkanes (1)
- COVID-19 (1)
- CRM (1)
- CRP (1)
- CUINS2 nanocrystals (1)
- CaCl emission bands (1)
- Cadmium (1)
- Calcite (1)
- Calcium (1)
- Calcium carbonate (1)
- Calcium carbonates (1)
- Calibrated fluorescence measurements (1)
- Calibration-free analysis (1)
- Cancer awareness measure (1)
- Cancer cells (1)
- Cancer risk (1)
- Canine olfactometry (1)
- Carbamazepine (1)
- Cardiac troponin (1)
- Cardiolipins (1)
- Cardiovascular (1)
- Carrier (1)
- Carrier protein (1)
- Carrier-Material (1)
- Carriers (1)
- Cconventional method (1)
- Cell studies (1)
- Cellular substructure (1)
- Cellulose (1)
- Cement clinker remnants (1)
- Cerium oxide (1)
- Charged dyes (1)
- Chelate (1)
- Chemical Process Control (1)
- Chemical Safety (1)
- Chemical evolution (1)
- Chemical protein modification (1)
- Chemiluminescence (1)
- Chemodosimeter (1)
- Chemometrics (1)
- Chicken antibodies (1)
- Chirality (1)
- Chlorides (1)
- Chlorine (1)
- Chlorine determination (1)
- Chloroanilines (1)
- Ciaaw.org (1)
- Citation (1)
- Citizen Science (1)
- Citrullinated (1)
- Classical primary measurement method (CPM) (1)
- Classification (1)
- Cleaning (1)
- Cleavage (1)
- Click chemistry (1)
- Climate (1)
- Clinical Biochemistry (1)
- Clones (1)
- Cmos (1)
- Cobaloxime complex (1)
- Cocoa (1)
- Collaborative trial (1)
- Collagen (1)
- Collection (1)
- Colloidal semiconductor nanocrystals (1)
- Color (1)
- Column holder (1)
- Combinatorial chemistry (1)
- Combinatorial peptide library (1)
- Combustion (1)
- Combustion Ion Chromatography (1)
- Combustion ion chromatography (CIC) (1)
- Commercial metal-organic frameworks (1)
- Commercialization (1)
- Compartmentalization (1)
- Competitive Immunoassay (1)
- Complexation (1)
- Compound-independent calibration (1)
- Concentration step (1)
- Concrete (1)
- Confiscation (1)
- Conformation (1)
- Conjugate (1)
- Construction (1)
- Construction products (1)
- Consumer Products (1)
- Continuous Processes (1)
- Continuous Sensor (1)
- Continuous processes (1)
- Conventional isotope ratio (1)
- Converter material (1)
- Coordination polymer (1)
- Core-shell (1)
- Core–shell particles (1)
- Corona virus (1)
- Corophium volutator (1)
- Corundum (1)
- Cr(III) complex (1)
- Cross section (1)
- Cross-sectioning (1)
- Crosslinker (1)
- Cryoadsorption (1)
- Cucurbituril (1)
- Customs (1)
- Cyanide in soil (1)
- Cyber-Physical Systems (1)
- Cyber-physical system (1)
- Cyclic voltammetry (1)
- Cyclometalated iridium (III) complexes (1)
- Cytoplasm (1)
- DFA (1)
- DFT (1)
- DHAP (1)
- DNA (1)
- DNA radiation damage (1)
- DNA strand breaks (1)
- DPA (1)
- Damage-associated molecular patterns (DAMPs) (1)
- Data (1)
- Data Fusion (1)
- Data infrastructures (1)
- Data processing (1)
- De novo peptide sequencing (1)
- Deep learning-based tools (1)
- Degradation (1)
- Degradation of refrigerants (1)
- Delta isotope standard (1)
- Delta value (1)
- Dendrimer (1)
- Density data (1)
- Design of experiment (1)
- Detection (1)
- Deterioration (1)
- Development (1)
- Diagnostic Antibodies (1)
- Diastolic dysfunction (1)
- Diatomic molecule (1)
- Diclofenac (1)
- Diesel exhaust (1)
- Diffusion (1)
- Digestion (1)
- Digital Transformation (1)
- Digital Twins (1)
- Digital holographic cytometry (1)
- Digital immunoassay (1)
- Digital representations (1)
- Digital transformation (1)
- Digital twins (1)
- Digital workflows (1)
- Digitalisierung der Prozessindustrie (1)
- Digitization of process industry (1)
- Dip-stick assay (1)
- Disinfection (1)
- Dissolution (1)
- Dityrosine crosslinking (1)
- Docking (1)
- Down Stream Processing (1)
- Downstream Processing (1)
- Downstream processing (1)
- Druckstabilität (1)
- Drug Discovery (1)
- Drug search (1)
- Drug trafficking (1)
- Dual sensing (1)
- Dual-color labeling glycan (1)
- Duplex stainless steels (1)
- Dyad (1)
- Dye loading optimisation (1)
- Dye monomers (1)
- Dye release (1)
- Dyes (1)
- Dyes/pigments (1)
- Dynamic calibration gas mixtures (1)
- EC/MS (1)
- ECR (1)
- EDTAD (1)
- EP-3533 (1)
- ESMA (1)
- EU-WFD (1)
- EXAFS (1)
- Early Earth (1)
- Ecotoxicity (1)
- Editorial (1)
- Elastin (1)
- Elastin-specific contrast agent ESMA (1)
- Elastin-specific molecular agent (1)
- Electrochemical (1)
- Electrochemical titration (1)
- Electron transfer (1)
- Elektrochemie (1)
- Elektrochemilumineszenz (1)
- Element Specific Bioimaging Using Laser Ablation (1)
- Emergency (1)
- Emission testing (1)
- Enantiomeric excess ee (1)
- Encapsulation (1)
- Encoding (1)
- Endokrine Disruptoren (1)
- Endokriner Disruptor (1)
- Enhancement strategy (1)
- Environment (1)
- Environmental Engineering (1)
- Environmental pollutants (1)
- Environmental simulations (1)
- Environmental speciation (1)
- Enzyme (1)
- Enzyme-Linked Immunosorbent Assay (1)
- Equation of state (1)
- Error correction (1)
- Escherichia coli (1)
- Esterification (1)
- Estrogens (1)
- Ethylenediaminetetraacetic acid (1)
- Etofenprox (1)
- European Reference Material (1)
- Evanescent wave (1)
- Ex vivo (1)
- Excimers (1)
- Excitation (1)
- Exhaust (1)
- Experiment (1)
- Explosiven (1)
- Explosives detection (1)
- Exposure (1)
- Extractable organically bound fluorine (EOF) (1)
- Extraction (1)
- FFF-3D printer (1)
- FFF-3D printing (1)
- FRET (1)
- False Positives (1)
- Feature selection (1)
- Fenton (1)
- Fenton’s reagent (1)
- Finow Canal (1)
- Flexible crystals (1)
- Flourescence (1)
- Flourescin (1)
- Flow injection immunoassay (1)
- Fluorescein (1)
- Fluorescence Polarization (1)
- Fluorescence label (1)
- Fluorescence life time (1)
- Fluorescence spectroscopy (1)
- Fluorescence standard (1)
- Fluorescent dyes (1)
- Fluorescent probes (1)
- Fluorescent sensors (1)
- Fluoreszenz (1)
- Fluorides (1)
- Fluorination (1)
- Fluoroacetic acid (1)
- Folding chirality (1)
- Food fermentation (1)
- Food safety (1)
- Forsterite (1)
- Fourier transform spectroscopy (1)
- Fow injection analysis (1)
- Fragmentation pathway (1)
- Freisetzung (1)
- Fully aromatic frameworks (1)
- Functional group quantification (1)
- Functional monomers (1)
- Fungicide (1)
- Funtional Groups (1)
- Fusarium (1)
- Fusarium mycotoxin (1)
- GC/MS (1)
- GC/MS-MS (1)
- GF-MAS (1)
- GMAW (1)
- Gadolinium-based contrast agent (1)
- Gadovist (1)
- Galvanic anodes (1)
- Gamma-hydroxybutyric acid (1)
- Gas analysis (1)
- Gas sensing (1)
- Gasoline (1)
- Gated materials (1)
- Gd-DOTA (1)
- General Chemistry (1)
- Genotoxicity testing (1)
- Geological material (1)
- Germanium chlorides (1)
- Gesteuerte Freisetzung (1)
- Gesteuerten Nanopartikeln (1)
- Ggadolinium (1)
- Github (1)
- Glasmonolith (1)
- Glass (1)
- Glass Support (1)
- Gold (1)
- Gold nanocluster (1)
- Grafting (1)
- Graphene (1)
- Graphite furnace (1)
- Grass pollen (1)
- Green light excitation (1)
- Grignard reaction (1)
- Grignard-Reaktion (1)
- Ground water (1)
- Groundwater (1)
- Group profile (1)
- Guanidinium receptors (1)
- Gypsum (1)
- Gypsum dehydration (1)
- HAXPES (1)
- HF free Digestion (1)
- HPLC-DAD/FLD (1)
- HPSEC (1)
- HR-CS-MAS (1)
- Hafnium (1)
- Hapten Immunoassay (1)
- Hay fever (1)
- Heart attack (1)
- Heat accumulation (1)
- Heat flow (1)
- Heat-transfer Measurements (1)
- Heavy chains (1)
- Hemihydrate (1)
- Hepatocellular carcinoma (1)
- Herceptin (1)
- HexaHis-Tag (1)
- High entropy alloy (1)
- High pH (1)
- High pressure experiments (1)
- High resolution-continuum source-graphite furnace molecular absorption spectrometry (HR-CS-GFMAS) (1)
- High-Speed (1)
- High-Speed Separations (1)
- High-fired gypsum (1)
- High-fired gypsum mortar (1)
- High-fired medieval gypsum mortars (1)
- High-frequency arc discharge (1)
- High-resolution continuum source graphite furnace atomic absorption spectrometry (1)
- High-resolution continuum source molecular absorption spectrometry (1)
- High-throughput (1)
- Highspeed (1)
- His6 (1)
- His8 (1)
- Histidine (1)
- Hot-electrons (1)
- Human Plasma (1)
- Human leukocyte antigen (HLA) (1)
- Human papillomavirus (1)
- Human serum albumin (1)
- Humic matter (1)
- Hydrated silicate melts (1)
- Hydration (1)
- Hydrochloric acid (1)
- Hydrodynamic chromatography (HDC) (1)
- Hydrodynamic model (1)
- Hydrogen Storage (1)
- Hydrogen adsorption (1)
- Hydrogen adsorption storage (1)
- Hydrogen reduction (1)
- Hydrogen uptake reproducibility (1)
- Hydrogen-containing gas mixture (1)
- Hydrothermal fluid (1)
- Hydroxy warfarin (1)
- ICP-MS/MS (1)
- ICP-TOFMS (1)
- ICP-ToF-MS (1)
- ID-MS (1)
- ILC (1)
- IMAC purification (1)
- IR spectroscopy; conductometry (1)
- ISO REMCO (1)
- Identity (1)
- IgE (1)
- IgG determination (1)
- IgY (1)
- Illicit drug (1)
- Image analysis (1)
- Image segmentation (1)
- Imaging Technique (1)
- Imidazole (1)
- Immobilisierung (1)
- Immunassay (1)
- Immunglobulin (1)
- Immunglobuline (1)
- Immunoassays (1)
- Immunoglobulin E (1)
- Immunohistochemistry (1)
- Immunology (1)
- Immunometric assay (1)
- Immunometric biosensor (1)
- Impact (1)
- Imprinting (1)
- In situ (1)
- In situ EXAFS (1)
- In situ SAXS/WAXS (1)
- In situ measurement (1)
- In vivo (1)
- In-house calibration solution (1)
- In-situ analysis (1)
- In-situ process monitoring (1)
- In-vivo (1)
- Indicator displacement assay (1)
- Indoor air quality (1)
- Inductively Coupled Mass Spectroscopy (1)
- Inductively coupled plasma mass spectroscopy (1)
- Inductively‑coupled mass spectrometry (1)
- Industrial gypsum (1)
- Inert gases (1)
- Infrared thermography (1)
- Infrastruktur (1)
- Inhibition (1)
- Inline Analytics (1)
- Inorganic chemical analysis (1)
- Inorganic impurities (1)
- Instrumental isotope fractionation (1)
- Inter layer time (1)
- Interferometric spectroscopy (1)
- Intermixing (1)
- Internal standard (1)
- International drug trade (1)
- Ion mobility spectrometry (1)
- Ionophore (1)
- Ionophore antibiotics (1)
- Iposomes (1)
- Iridium (1)
- Isotope Dilution (1)
- Isotope Labelling (1)
- Isotope amount ratio (1)
- Isotope delta value (1)
- Isotope dilution mass spectrometry (1)
- Isotope reference material (1)
- Isotope-labeled (1)
- Isotopic analysis (1)
- Isotopic fractionation (1)
- Isotopologue Distribution (1)
- Iterative real-time optimization (1)
- Jahrestag (1)
- Job plot (1)
- Kjeldahl (1)
- Knowledge graphs (1)
- Kompost (1)
- LA/ICP-MS Imaging (1)
- LC-MS (1)
- LC-UV absorbance (1)
- LC/HRMS (1)
- LC/MS-MS (1)
- LFIA (1)
- LSVEC (1)
- Lab on a chip (1)
- Lab-on-a-Chip (1)
- Laboratory 4.0 (1)
- Lacunary Keggin ion (1)
- Ladder sequencing (1)
- Lasalocid (1)
- Laser Ablation (1)
- Laser ablation-inductively coupled plasma-mass spectrometry (1)
- Laser ablation-inductively coupled plasma-mass spectroscopy (1)
- Laser induced breakdown Spectrocopy (LIBS) (1)
- Laser induced breakdown spectroscopy (1)
- Laser induced plasma (1)
- Laser induced plasma deposition (1)
- Laser powder bed fusion (1)
- Laser-induced breakdown spectroscopy (1)
- Laser-induced dielectric breakdown (LIDB) (1)
- Laser-induced fluorescence (1)
- Lastwechsel (1)
- Layer-by-Layer (1)
- Layers (1)
- Leaching (1)
- Lead (1)
- Legacy pollution (1)
- LiYF4 (1)
- Library (1)
- Life science (1)
- Lifetime encoding (1)
- Lifetime-encoded beads (1)
- Light chain (1)
- Light chains (1)
- Light harvesting (1)
- Lipidomics (1)
- Lipids (1)
- Liquid chromatography (1)
- Liver X receptor (1)
- Lluminescence (1)
- Longst luminescence lifetime (1)
- Low-cost (1)
- Low-energy electrons (1)
- Luminescent lifetime (1)
- Luminol (1)
- Lymnaea stagnalis (1)
- Lysergic acid hydrazide (1)
- Lysosome (1)
- MALDI-TOF-MS (1)
- MC-TIMS (1)
- MCR (1)
- MIC (1)
- MICAP-MS (1)
- MIP (1)
- MLCT (1)
- MOF´s (1)
- MOSH/MOAH (1)
- MR Angiography (1)
- MR imaging (1)
- MST (1)
- MW-AES (1)
- MYCN (1)
- Machine learning (1)
- Macrophages (1)
- Magnesium (1)
- Magnesium carbonates (1)
- Magnetic (1)
- Magnetic nanocatalyst (1)
- Magnetpartikel (1)
- Mass-Spectrometry (1)
- Massenspektrometrie (1)
- Material sciences (1)
- Materials informatics (1)
- Mechanical properties (1)
- Medical diagnostics (1)
- Medicinal application (1)
- Medicine (1)
- Medium entropy alloy (1)
- MefHySto (1)
- Mercury speciation (1)
- Meso Portland cement (1)
- Mesofluidics (1)
- Mesoporous particles (1)
- Metabolic Flux (1)
- Metabolization (1)
- Metal cluster (1)
- Metal toxicity (1)
- Metal uptake (1)
- Metalloprotein (1)
- Metals (1)
- Metal−organic frameworks (1)
- Methanol oxidation (1)
- Methylanilines (1)
- Methylmercury (1)
- Metrologie (1)
- Metrology in chemistry (1)
- Microbe interactions (1)
- Microfluidic (1)
- Microfluidic mixing (1)
- Microfluidic system (1)
- Micrometeorites (1)
- Microorganism (1)
- Microplastic-induced effects (1)
- Microplatic (1)
- Microscope slides (1)
- Microwave inductively coupled atmospheric pressure mass spectrometry (MICAP-MS) (1)
- Microwave-assisted synthesis (1)
- Miller and Urey (1)
- Mineral identification (1)
- Mineral oil hydrocarobons (1)
- Mineral paragenesis (1)
- Miniaturization (1)
- Missing fragmentation sites (1)
- Mixed surface (1)
- Mixture toxicity (1)
- Mobile analytics (1)
- Mobile phase (1)
- Model Predictive Control (1)
- Modeling (1)
- Modified mycotoxins (1)
- Modifier adaptation (1)
- Molecular Biology (1)
- Molecular MRI (1)
- Molecular Organic Frameworks (1)
- Molecular imprinted polymers (1)
- Molecular marker (1)
- Molecular spectra (1)
- Molecular-MRI (1)
- Molecule (1)
- Monensin (1)
- Monoclonal Antibody (1)
- Monoclonal antibodies (1)
- Monolith (1)
- Monomer (1)
- Monte Carlo algorithm (1)
- Mounting media (1)
- Multi-collector inductively coupled plasma-mass spectrometry (ICP-MS) (1)
- Multi-element analysis (1)
- Multi-prinicpal element alloys (MPEAs) (1)
- Multiple sclerosis (1)
- Multiple-injection sample-standard bracketing (1)
- Multiplexed assay (1)
- Multivariat (1)
- Multivariate (1)
- Multivariate data analysis (1)
- Multivariate methods (1)
- Murchison meteorite (1)
- NIR Spectroscopy (1)
- NIR dyes (1)
- NIR-I (1)
- NIR-II fluorescence (1)
- NIST (1)
- NIST-mAb 8671 (1)
- NMR Spectroscopy (1)
- NMR spectroscopy (1)
- NMR-Spektroskopie (1)
- NSE (1)
- Nanaoparticle (1)
- Nanaoparticles (1)
- Nano-carrier (1)
- Nanocarrier (1)
- Nanolenses (1)
- Nanomaterial design (1)
- Nanoparticle characterization (1)
- Nanoparticle dimers (1)
- Nanopartikel (1)
- Nanopowder (1)
- Nanosafety (Safe-by-design) (1)
- Nanoscience (1)
- Nanosciences (1)
- Nanostructures (1)
- Naphthalene (Nap) (1)
- Narcotics (1)
- Neoallergen (1)
- Neoepitopes (1)
- Neural networks (1)
- Neutral dyes (1)
- Nickel chelate (1)
- Nile Red (1)
- Nitrogen dioxide (1)
- Nitrogen microwave inductively coupled atmospheric pressure mass spectrometry (1)
- Nitrogen monoxide (1)
- Nitrogen plasma (1)
- Non-targeted analysis (1)
- Nonspecific binding (NSB) (1)
- Nuclear Magnetic Resonance Spectroscopy (1)
- Nuclear receptor (1)
- Nucleocapsid (1)
- OBOC library (1)
- Ochratoxin A (1)
- Oil spills (1)
- Oligomerization (1)
- Oligonucleotides (1)
- On-chip screening (1)
- On-line CE/MC-ICP-MS (1)
- On-site detection (1)
- One-bead-one-compound library (1)
- Online NMR Spectroscopy (1)
- Online NMR spectroscopy (1)
- Online biosensor (1)
- Online detection (1)
- Ontologies (1)
- Open science (1)
- Optical assay (1)
- Optical imaging (1)
- Optically active surfaces (1)
- Organic Synthesis (1)
- Organic calibration solution (1)
- Organic contaminants (1)
- Organic-inorganic hybrid composites (1)
- Organic–inorganic nanostructures (1)
- Oriented immobilization (1)
- Osmotic minipumps (1)
- Oxidative metabolism (1)
- Oxygen evolution reaction (1)
- Oxygen isotope ratios (1)
- Oxygen sensitive (1)
- PAHs (1)
- PCA (1)
- PDT (1)
- PEM-Wasserelektrolyse (1)
- PIC technology (1)
- PLSR (1)
- PSA (1)
- Packing density (1)
- Pants (1)
- Partial least square discriminant analysis (PLS-DA) (1)
- Particle architecture (1)
- Particle synthesis (1)
- Pattern recognition receptor (1)
- Pd(II) (1)
- Peer review (1)
- Peptide aptamers (1)
- Peptide binder (1)
- Peptide folding (1)
- Peptide mass fingerprinting (1)
- Peptide probe (1)
- Peptides (1)
- Peptides and Proteins (1)
- Per- and Polyfluoroalkyl substances (PFAS) (1)
- Per- and polyfluorinated alkyl substances (PFASs) (1)
- Perfluorooctanoic Acid (PFOA) (1)
- Permethrin (1)
- Peroxidase (1)
- Perturbed-Chain Statistical Association Fluid Theory (1)
- Pesticide (1)
- Pestizid (1)
- Petroleum (1)
- Pflanzenvirus (1)
- Pflanzenwachstum (1)
- Ph (1)
- Pharmaceutical (1)
- Pharmaceutical Science (1)
- Phase Imaging (1)
- Phenanthrene (1)
- Phenothrin (1)
- Phenylketonuria (1)
- Phl p 5 (1)
- Phleum pratense (1)
- Phosphinine (1)
- Phospholipids (1)
- Phosphor (1)
- Phosphorescence (1)
- Phosphorus elimination (1)
- Phosphorus recovery (1)
- Photocatalysis (1)
- Photocatalytic reduction (1)
- Photochemistry (1)
- Photoinduced Electron Transfer (1)
- Photoinduced electron transfer (1)
- Photonic biosensor (1)
- Photosensitization (1)
- Photostability (1)
- Physical and theoretical chemistry (1)
- Physical twin (1)
- Physico-chemical characterisation of minerals (1)
- Phytoliths (1)
- Planck function (1)
- Plant virus (1)
- Plant-model mismatch (1)
- Plasma (1)
- Plasma chemistry (1)
- Plasmonic heating (1)
- Plastic deformation (1)
- Polarised light microscopy (1)
- Polarity (1)
- Polishing (1)
- Pollen (1)
- Pollen extract (1)
- Pollutant (1)
- Polyclonal Antibodies (1)
- Polycyclic aromatic hydrocarbons (1)
- Polyelektrolyt (1)
- Polyglycerol (1)
- Polymer particles (1)
- Polymer-based products (1)
- Polymere (1)
- Polymerization (1)
- Polymers (1)
- Polyoxometalates (1)
- Polystyrene microparticles (1)
- Pore fluids (1)
- Porous rock (1)
- Porphyrin (1)
- Portable (1)
- Portland clinker (1)
- Potash (1)
- Powder X-ray diffraction (1)
- Power density (1)
- Pphotophysics (1)
- Prebiotic chemistry (1)
- Precision agriculture (1)
- Precision farming (1)
- Preprocessing (1)
- Primary difference measurement method (PDM) (1)
- Primary transfer standards (PTSs) (1)
- Primordial soup (1)
- Principal component analysis (PCA) (1)
- Priority effect (1)
- Process Analytical Tecnology (1)
- Process Control (1)
- Process control (1)
- Process industry (1)
- Process intelligence (1)
- Process monitoring (1)
- Process sensors 4.0 (1)
- Programmed cell death (1)
- Proinflammatory cytokines (1)
- Protein Purification (1)
- Protein content (1)
- Protein degradation (1)
- Protein folding (1)
- Protein hydrolysis (1)
- Protein oligomerization (1)
- Protein oligomers (1)
- Protein quantification (1)
- Protein test (1)
- Protein-modification (1)
- Proteinoid (1)
- Prouess-Sensoren 4.0 (1)
- Provenance (1)
- Provenancing (1)
- Proximal soil sensing (1)
- Prozessanalytik (1)
- Prozesskontrolle (1)
- Pseudomonas aeruginosa (1)
- Pt(111) (1)
- Pt(II) (1)
- PtNP (1)
- Public Health, Environmental and Occupational Health (1)
- Purity (1)
- Quality assurancemechanism (1)
- Quality control (1)
- Quantitative Analysis (1)
- Quantitative determination (1)
- Quantitative protein analysis (1)
- Quantum chemistry (1)
- Quartz (1)
- R package (1)
- RBD (1)
- REMPI (1)
- Racemate (1)
- Rainwater (1)
- Raman band width (1)
- Raman microscopy (1)
- Raman-spectroscopy (1)
- Rapid test (1)
- Rapid tests (1)
- Rat/human liver microsomes (1)
- Ratiometric (1)
- Reactor control (1)
- Real-time imaging (1)
- Real-time quality control (1)
- Recombinant Antibody (1)
- Recombinant antibody (1)
- Recombinant protein (1)
- Redox (1)
- Redox switch (1)
- Reference (1)
- Reference Material (1)
- Reference Materials (1)
- Reference data (1)
- References (1)
- Reinigung (1)
- Reliability (1)
- Renal disease (1)
- Renewable copolymers (1)
- Replication (1)
- Replication crisis (1)
- Reporter (1)
- Reproducibility crisis (1)
- Resistance (1)
- Resonance wavelength shift (1)
- Reverse microemulsion (1)
- Reversible covalent hydrazine chemistry (RCHC) (1)
- Rheumatoid arthritis (1)
- Rhizopus (1)
- Rhizopus and Aspergillus oryzae (1)
- Rhodamine (1)
- Ring resonator (1)
- River water sulfate (1)
- Robustness (1)
- Rosamine (1)
- Roughness (1)
- Ruthenium(II) complexes (1)
- Rückverstromung (1)
- SA conjugates (1)
- SAXS (1)
- SBA-15 (1)
- SBA-16 (1)
- SEC (1)
- SEM (1)
- SERDS (1)
- SERS (1)
- SI Traceability (1)
- SIDA-LC-MS/MS (1)
- SKPFM (1)
- SOM-SM (1)
- SPR (1)
- SVOC (1)
- Safe by design (1)
- Salicylic acid (1)
- Salinomycin (1)
- Salts (1)
- Sample preparation (1)
- Scale anchor (1)
- Scale conversion (1)
- Scattering (1)
- Schlangenbohne (1)
- Schlieren Imaging (1)
- Schnelltest (1)
- Schnelltests (1)
- Scientific publication (1)
- Seawater (1)
- Security (1)
- Sediment (1)
- Segregation (1)
- Selenium (1)
- Self-absorption (1)
- Self-assembled monolayers (SAM) (1)
- Semiconductor (1)
- Semiconductor nanocrystals (1)
- Semiconductor quantum dot (1)
- Sensor Materials (1)
- Sensory particles (1)
- Separation (1)
- Sequence dependence (1)
- Sequencing (1)
- Sequencing algorithm (1)
- Shadowgraphy (1)
- Silanization (1)
- Silica and polystyrene nanoparticles (1)
- Silica coating (1)
- Silica diagenesis (1)
- Silicon (1)
- Silicon chlorides (1)
- Simulation (1)
- Single Cell (1)
- Single enhancement (1)
- Single particle ICP-MS (1)
- Single-cell analysis (1)
- Singlet oxygen (1)
- Sintered Material (1)
- Small-angle scattering (1)
- Smart actuators (1)
- Smart test laboratories (1)
- Smarte Aktoren (1)
- Smarte Sensoren (1)
- Smarter Sensor (1)
- Smartphone readout (1)
- Soil contact (1)
- Soil heterogeneity (1)
- Sol-gel process (1)
- Solar cells (1)
- Solar concentrator (1)
- Solar energy (1)
- Solid (1)
- Solid state (1)
- Solid state emission (1)
- Solid support (1)
- Solid-phase extraction (SPE) (1)
- Sorghum (1)
- Spark plasma sintering (1)
- Spatial heterodyne spectrometer (1)
- Special issue (1)
- Specific probe (1)
- Spectoscopic imaging (1)
- Spectrometer (1)
- Spectrometry (1)
- Spectroscopic imaging (1)
- Spectroscopy / Instrumentation (1)
- Spectroscopy / Theory (1)
- Speed of sound (1)
- Spike protein (1)
- Sr isotope analysis (1)
- SsNMR (1)
- Stability (1)
- Stabilization (1)
- Stable isotopes (1)
- Standard atomic weight (1)
- Stationäre Phase (1)
- Statistics (1)
- Steel (1)
- Stepwise growth (1)
- Stranski–Krastanow growth (1)
- Strontium isotope (1)
- Structural Biology (1)
- Structure-property relationship (1)
- Sub-4nm particles (1)
- Substance release (1)
- Sulfide sensing (1)
- Sulfur (1)
- Sulfur isotopes (1)
- Sulphur isotope (1)
- Sum Parameter (1)
- Sum Parameter Method (1)
- Sum parameter method (1)
- Supported catalyst (1)
- Supramolecular Chemistry (1)
- Surface Chemistry (1)
- Surface coating (1)
- Surface derivatization (1)
- Surface ligand (1)
- Surface plasmon resonance (1)
- Surface waters (1)
- Surface-enhanced Raman scattering (1)
- Surrogate citations (1)
- Sustainable Production (1)
- Suzuki coupling (1)
- Suzuki-Miyaura coupling (1)
- Swell-capture (1)
- Synchrotron FTIR (1)
- Synthetic peptides (1)
- TEM (1)
- TFA (1)
- TLR4 activation (1)
- Tantalum oxyfluorides (1)
- Target (1)
- Tau (1)
- Temperature (1)
- Temperature Control (1)
- Terephthalic acid (1)
- Terrorism (1)
- Test strip (1)
- Tetracyclin (1)
- Tetramethylammonium hydroxide (1)
- Theranostic (1)
- Therapeutic Antibodies (1)
- Thermal Process Engineering (1)
- Thermocouple (1)
- Thermodynamic analysis (1)
- Thermography (1)
- Thick shells (1)
- Thickness (1)
- Thin films (1)
- Tholins (1)
- Tissue (1)
- Titan-Halterung (1)
- Titanium dioxide (1)
- ToF-SIMS (1)
- Toll-like receptor 4 (1)
- Tomography (1)
- Topical collection: Analytical Methods and Applications in the Materials and Life Sciences (1)
- Total cyanide (1)
- Total element determination (1)
- Toxicity testing (1)
- Toys (1)
- Trace Analysis (1)
- Transferrin (1)
- Transformation (1)
- Transient signal (1)
- Transpassive dissolution (1)
- Trastuzumab (1)
- Trennung (1)
- Truffle (1)
- Truffle Aroma (1)
- Trust (1)
- Tryptic digest (1)
- Tryptophan (1)
- Tuber melanosporum (1)
- Tutzing Symposion (1)
- Type-I pyrethroids (1)
- UV Vis (1)
- UV radiation (1)
- UV–Vis spectroscopy (1)
- Ultrasensitive (1)
- Umweltschadstoffe (1)
- Upconverion (1)
- Upconverstion (1)
- Upscaling (1)
- VO (1)
- VVOC (1)
- Validate method (1)
- Validation trial (1)
- Vanadium (1)
- Vanadium oxide catalysts (1)
- Vegetable edible oil (1)
- Veterinary drugs (1)
- Vigna unguiculata (1)
- Virial coefficients (1)
- Visualization (1)
- Vocabulary providers (1)
- Volatile organic compounds (1)
- Volatile organic compounds; (1)
- Volumetric uptake (1)
- Vor-Ort-Analytik (1)
- WD-XRF (1)
- WWTP (1)
- Warfarin (1)
- Wasser (1)
- Wasserstoff (1)
- Wasserstoff-Qualität (1)
- Wasserstoffspeicher (1)
- Wastewater (1)
- Water (1)
- Water contact (1)
- Whole water samples (1)
- Wipe test (1)
- Wood chips (1)
- Work function (1)
- X-Ray analysis (1)
- X-Ray fluorescence (1)
- X-ray (1)
- X-ray diffraction (1)
- X-ray spectroscopy (1)
- XANES (1)
- Yerba mate tea (1)
- Ytterbium (1)
- Zearalenone (1)
- Zearalenone sulfate (1)
- Zellulose (1)
- Zenodo (1)
- Zeolithe (1)
- Zinc (1)
- Zinc oxide (1)
- a-zearalenol (1)
- biokompatibel (1)
- calibration (1)
- compost (1)
- dye (1)
- gesintert (1)
- lank characterization (1)
- magnetic nanocatalysts (1)
- pH probe (1)
- photoluminescence (1)
- research landscape (1)
- self-replication (1)
- spICP-MS (1)
- species-specific isotope information (1)
- tandard addition (1)
- temperature (1)
- thermophysical properties (1)
- transmission mode (1)
- β-Lactam (1)
- γ-H2AX assay (1)
Organisationseinheit der BAM
- 1 Analytische Chemie; Referenzmaterialien (355) (entfernen)
Paper des Monats
- ja (11)
Changes in the global bulk and local structures, of three different barium compounds (BaZrO3, BaF2, and BaFCl),were induced by mechanical milling and followed using X-ray powder diffraction (PXRD), subsequent microstructure analysis, and 137Ba solid state NMR spectroscopy. Harder materials like BaZrO3 experience significantly higher structural changes upon milling than softer materials like BaF2. Moreover, soft materials with layered structures, like BaFCl, show a pronounced structural change during the milling process. By combining PXRD and solid state NMR, detailed information on the changes to the global and local structures were obtained, which are of interest for mechanochemical synthesis, mechanically treated catalysts or ionic conductors.
Determination of elemental mass fractions in sediments plays a major role in evaluating the environmental status of aquatic ecosystems. Herewith, the optimization of a new total digestion protocol and the subsequent analysis of 48 elements in different sediment reference materials (NIST SRM 2702, GBW 07313, GBW 07311 and JMC-2) based on ICP-MS/MS detection is presented. The developed method applies microwave acid digestion and utilizes HBF4 as fluoride source for silicate decomposition. Similar to established protocols based on HF, HBF4 ensures the dissolution of the silicate matrix, as well as other refractory oxides. As HBF4 is not acutely toxic; no special precautions have to be made and digests can be directly measured via ICP-MS without specific sample inlet systems, evaporation steps or the addition of e.g. H3BO3, in order to mask excess HF. Different acid mixtures with and without HBF4 were evaluated in terms of digestion efficiency based on the trace metal recovery. The optimized protocol (5 mL HNO3, 2 mL HCL, 1 mL HBF4) allows a complete dissolution of the analyzed reference materials, as well as quantitative recoveries for a wide variety of certified analytes. Low recoveries for e.g. Sr, Ba and rare earth elements due to fluoride precipitation of HF-based digestions protocols, can be avoided by the usage of HBF4 instead. Based on the usage of high purity HBF4 all relevant trace, as well as matrix elements can be analyzed with sufficiently low LOQs (0.002 μg L−1 for U up to 6.7 μg L−1 for Al). In total, 34 elements were within a recovery range of 80%–120% for all three analyzed reference materials GBW 07313, GBW 07311 and JMC-2. 14 elements were outside a recovery range of 80%–120% for at least one of the analyzed reference materials.
Environmental pollutants like fine particulate matter can cause adverse health effects through oxidative stress and inflammation. Reactive oxygen and nitrogen species (ROS/RNS) such as peroxynitrite can chemically modify proteins, but the effects of such modifications on the immune system and human health are not well understood. In the course of inflammatory processes, the Toll-like receptor 4 (TLR4) can sense damage-associated molecular patterns (DAMPs). Here, we investigate how the TLR4 response and pro-inflammatory potential of the proteinous DAMPs α-Synuclein (α-Syn), heat shock protein 60 (HSP60), and high-mobility-group box 1 protein (HMGB1), which are relevant in neurodegenerative and cardiovascular diseases, changes upon chemical modification with peroxynitrite.
For the peroxynitrite-modified proteins, we found a strongly enhanced activation of TLR4 and the pro-inflammatory transcription factor NF-κB in stable reporter cell lines as well as increased mRNA expression and secretion of the pro-inflammatory cytokines TNF-α, IL-1β, and IL-8 in human monocytes (THP-1). This enhanced activation of innate immunity via TLR4 is mediated by covalent chemical modifications of the studied DAMPs.
Our results show that proteinous DAMPs modified by peroxynitrite more potently amplify inflammation via TLR4 activation than the native DAMPs, and provide first evidence that such modifications can directly enhance innate immune responses via a defined receptor. These findings suggest that environmental pollutants and related ROS/RNS may play a role in promoting acute and chronic inflammatory disorders by structurally modifying the body's own DAMPs. This may have important consequences for chronic neurodegenerative, cardiovascular or gastrointestinal diseases that are prevalent in modern societies, and calls for action, to improve air quality and climate in the Anthropocene.
Luminescence lifetimes are an attractive analytical method for detection due to its high sensitivity and stability. Iridium probes exhibit luminescence with long excited-state lifetimes, which are sensitive to the local environment. Perfluorooctanoic acid (PFOA) is listed as a chemical of high concern regarding its toxicity and is classified as a “forever chemical”. In addition to strict limits on the presence of PFOA in drinking water, environmental contamination from industrial effluent or chemical spills requires rapid, simple, accurate, and cost-effective analysis in order to aid containment. Herein, we report the fabrication and function of a novel and facile luminescence sensor for PFOA based on iridium modified on gold surfaces. These surfaces were modified with lipophilic iridium complexes bearing alkyl chains, namely, IrC6 and IrC12, and Zonyl-FSA surfactant. Upon addition of PFOA, the modified surfaces IrC6-FSA@Au and IrC12-FSA @Au show the largest change in the red luminescence signal with changes in the luminescence lifetime that allow monitoring of PFOA concentrations in aqueous solutions. The platform was tested for the measurement of PFOA in aqueous samples spiked with known concentrations of PFOA and demonstrated the capacity to determine PFOA at concentrations >100 μg/L (240 nM).
Spatial heterodyne spectroscopy (SHS) is a novel spectral analysis technique that is being applied for Raman spectroscopy of minerals. This paper presents the theoretical basis of SHS and its application for Raman measurements of calcite, quartz and forsterite in marble, copper ore and nickel ore, respectively. The SHS measurements are done using a broadband (518–686 nm) and resolving power R ≈ 3000 instrument. The spectra obtained using SHS are compared to those obtained by benchtop and modular dispersive spectrometers. It is found that SHRS performance in terms of resolution is comparable to that of the benchtop spectrometer and better than the modular dispersive spectrometer, while the sensitivity of SHRS is worse than that of a benchtop spectrometer, but better than that of a modular dispersive spectrometer. When considered that SHS components are small and can be packaged into a handheld device, there is interest in developing an SHS-based Instrument for mobile Raman spectroscopy. This paper evaluates the possibility of such an application.
Raman microspectra combine information on chemical composition of plant tissues with spatial information. The contributions from the building blocks of the cell walls in the Raman spectra of plant tissues can vary in the microscopic sub-structures of the tissue. Here, we discuss the analysis of 55 Raman maps of root, stem, and leaf tissues of Cucumis sativus, using different spectral contributions from cellulose and lignin in both univariate and multivariate imaging methods. Imaging based on hierarchical cluster analysis (HCA) and principal component analysis (PCA) indicates different substructures in the xylem cell walls of the different tissues. Using specific signals from the cell wall spectra, analysis of the whole set of different tissue sections based on the Raman images reveals differences in xylem tissue morphology. Due to the specifics of excitation of the Raman spectra in the visible wavelength range (532 nm), which is, e.g., in resonance with carotenoid species, effects of photobleaching and the possibility of exploiting depletion difference spectra for molecular characterization in Raman imaging of plants are discussed. The reported results provide both, specific information on the molecular composition of cucumber tissue Raman spectra, and general directions for future imaging studies in plant tissues.
In this study, we demonstrate the applicability of nitrogen microwave inductively coupled atmospheric pressure mass spectrometry (MICAP-MS) for Ca, Fe, and Se quantification in human serum using isotope dilution (ID) analysis. The matrix tolerance of MICAP-MS in Na matrix was investigated, uncovering that high Na levels can suppress the signal intensity. This suppression is likely due to the plasma loading and the space charge effect. Moreover, 40Ca and 44Ca isotopic fractionation was noted at elevated Na concentration. Nine certified serum samples were analyzed using both external calibration and ID analysis. Overestimation of Cr, Zn, As, and Se was found in the results of external calibration, which might be resulted from C-induced polyatomic interference and signal enhancement, respectively. Further investigations performed with methanol showed a similar enhancement effect for Zn, As, and Se, potentially supporting this assumption. The mass concentrations determined with ID analysis show metrological compatibility with the reference values, indicating that MICAP-MS combined with ID analysis can be a promising method for precise Ca, Fe, and Se determination. Moreover, this combination reduces the influences of matrix effects, broadening the applicability of MICAP-MS for samples with complex matrix.
In this study, we employed nitrogen microwave inductively coupled atmospheric-pressure plasma (MICAP) combined with quadrupole mass spectrometry (MS) and a liquid sample introduction system to analyze heavy metals in soils. The vanadium, cobalt, nickel, zinc, copper, chromium, arsenic, lead, and cadmium contents in seven reference and three environmental soil samples determined using MICAP-MS were within the uncertainty of the reference values, indicating that MICAP-MS is promising for soil analysis similar to the conventional inductively coupled plasma mass spectrometry (ICP-MS) technique. In addition, the limits of detection (LODs) and sensitivity of both techniques using N2 and Ar plasma were of the same order of magnitude. Furthermore, the performance of MICAP-MS under different N2 purity was investigated, and we found that the plasma formation and ionization efficiency were not influenced by the impurities in the gas. A prominent advantage of MICAP-MS is the low operating cost associated with gas consumption. In this work, MICAP-MS used nitrogen, which is cheaper than argon, and consumed 25% less gas than ICP-MS. Using low-purity N2 can further reduce the gas cost, making MICAP-MS more cost effective than ICP-MS. These results suggest that MICAP-MS is a promising alternative to ICP-MS for the analysis of heavy metals in the soil.
The visualization of index-of-refraction (IoR) distribution is one of the common methods to investigate fluid flow or pressure fields. While schlieren and shadowgraphy imaging techniques are widely accepted, their inherent limitations often lead to difficulties in elucidating the IoR distribution and extracting the true IoR information from the resulting images. While sophisticated solutions exist, the IoR-gradient-to-image was achieved by purposely introducing a commonly avoided “defect” into the optical path of a conventional coincident schlieren/shadowgraphy setup; the defect is a combination of slight defocusing and the use of non-conjugate optical components. As such, the method presented in this work is referred to as defocusing shadowgraphy, or DF-shadowgraphy. While retaining the ease of a conventional schlieren/shadowgraphy geometry, this DF approach allows direct visualization of complicated resonant acoustic fields even without any data processing. For instance, the transient acoustic fields of a common linear acoustic resonator and a two-dimensional one were directly visualized without inversion. Moreover, the optical process involved in DF-shadowgraphy was investigated from a theoretical perspective. A numerical solution of the sophisticated impulse response function was obtained, which converts the phase distortion into intensity distributions. Based on this solution, the IoRs of various gas streams (e.g., CO2 and isopropanol vapor) were determined from single images.
The ability to controllably move gaseous ions is an essential aspect of ion-based spectrometry (e.g., mass spectrometry and ion mobility spectrometry) as well as materials processing. At higher pressures, ion motion is largely governed by diffusion and multiple collisions with neutral gas molecules. Thus, high-pressure ion optics based on electrostatics require large fields, radio frequency drives, complicated geometries, and/or partially transmissive grids that become contaminated. Here, we demonstrate that low-power standing acoustic waves can be used to guide, block, focus, and separate beams of ions akin to electrostatic ion optics. Ions preferentially travel through the static-pressure regions (“nodes”) while neutral gas does not appear to be impacted by the acoustic field structure and continues along a straight trajectory. This acoustic ion manipulation (AIM) approach has broad implications for ion manipulation techniques at high pressure, while expanding our fundamental understanding of the behavior of ions in gases.