3-Bromopyruvic acid (3BP) is a potential anticancer drug, the action of which on cellular metabolism is not yet entirely clear. The presence of a bromine atom suggests that it is also reactive towards low-energy electrons, which are produced in large quantities during tumour Radiation therapy. Detailed knowledge of the interaction of 3BP with secondary electrons is a prerequisite to gain a complete picture of the effects of 3BP in different forms of Cancer therapy. Herein, dissociative electron attachment (DEA) to 3BP in the gas phase has been studied both experimentally by using a crossed-beam setup and theoretically through scattering and quantum chemical calculations. These results are complemented by a vacuum ultraviolet absorption spectrum.
The main fragmentation channel is the formation of Br@ close to 0 eV and within several resonant features at 1.9 and 3–8 eV. At low electron energies, Br@ formation proceeds through s* and p* shape resonances, and at higher energies through core-excited resonances. It is found that the electron-capture cross-section is clearly increased compared with that of non-brominated pyruvic acid, but, at the same time, fragmentation reactions through DEA are significantly altered as well. The 3BP transient negative ion is subject to a lower number of fragmentation reactions than those of pyruvic acid, which indicates that 3BP could indeed act by modifying the electron-transport chains within oxidative phosphorylation. It could also act as a radio-sensitiser.
Microstructural aspects of composites such as reinforcement particle size, shape, and distribution play important roles in deformation behavior. In addition, Fe-rich inclusions and porosity also influence the behavior of these composites, particularly under fatigue loading. Three-dimensional (3-D) visualization of porosity and Fe-rich inclusions in three dimensions is critical to a thorough understanding of fatigue resistance of metal matrix composites (MMCs), because cracks often initiate at these defects. In this article, we have used X-ray synchrotron tomography to visualize and quantify the morphology and size distribution of pores and Fe-rich inclusions in a SiC particle-reinforced 2080 Al alloy composite. The 3-D data sets were also used to predict and understand the influence of defects on the deformation behavior by 3-D finite element modeling.
UHPC-AAC/CLC composite panels with self-cleaning properties. Materials and production technology
(2016)
The aim of this study is to show the development of a façade composite panel combining either an autoclaved aerated concrete or a cellular lightweight concrete insulation layer with a box-type external ultra-high performance concrete (UHPC) supporting layer. The paper presents the materials characteristics of the different components and the production technology of the panel. The efficiency of surface modifications of the materials forming the external shell of the panel is reported. The activation of self-cleaning properties is described. The test results showed that the most efficient way to use the water-repellent agent is its application on the substrate before the concrete cast. Concerning the production technology, the preliminary studies showed more advantages of a twostep manufacturing procedure of the UHPC boxes than a one-step procedure.
The awareness of the environmental impact of the building sector is increasing. Steel reinforced concrete is the most commonly used construction material, though with a high-embodied energy and carbon footprint. Large environmental gains may arise if an alternative to steel reinforced concrete is developed. In this context, ultra-high performance concrete (UHPC) materials are shown to be promising alternatives with advantages such as lower embodied energy and reduced environmental impact. Predictions suggest that UHPC composite elements for building envelopes could have other benefits such as an increased service life, optimised use of building area due to thinner elements and minimised maintenance due to the absence of reinforcement or use of non-corrosive reinforcing materials such as carbon fibres. In the framework of the H-HOUSE project funded by the European Commission, composite elements are developed. The aim is to create facade panels combining an autoclaved aerated concrete or cellular lightweight concrete insulation layer with an external UHPC supporting layer. To enhance occupant comfort and health, hygroscopic materials that are capable to buffer indoor air humidity shall be applied to the inside of such elements. Indoor air humidity levels are expected to be more stable, which shall subsequently improve the indoor climate and minimise potential decay to the construction.
The awareness of the environmental impact of the building sector is increasing. Steel reinforced concrete is the most commonly used construction material, though with a high-embodied energy and carbon footprint. Large environmental gains may arise if an alternative to steel reinforced concrete is developed. In this context, ultra-high performance concrete (UHPC) materials are shown to be promising alternatives with advantages such as lower embodied energy and reduced environmental impact. Predictions suggest that UHPC composite elements for building envelopes could have other benefits such as an increased service life, optimised use of building area due to thinner elements and minimised maintenance due to the absence of reinforcement or use of non-corrosive reinforcing materials such as carbon fibres. In the framework of the H-HOUSE project funded by the European Commission, composite elements are developed. The aim is to create facade panels combining an autoclaved aerated concrete or cellular lightweight concrete insulation layer with an external UHPC supporting layer. To enhance occupant comfort and health, hygroscopic materials that are capable to buffer indoor air humidity shall be applied to the inside of such elements. Indoor air humidity levels are expected to be more stable, which shall subsequently improve the indoor climate and minimise potential decay to the construction.
TrainMiC® is a European programme for lifelong learning on how to interpret the metrological requirements in chemistry. It is operational across many parts of Europe via national teams. These teams use shareware pedagogic tools which have been harmonised at European level through the joint effort of many experts across Europe working as an editorial board. The material has been translated into 14 different languages. This report includes four TrainMiC® presentations: 1. Uncertainty of measurement — Part I Principles; 2. Uncertainty of measurement — Part II Approaches to evaluation; 3. Statistics for analytical chemistry — Part I; and 4. Statistics for analytical chemistry — Part II
This paper presents an innovative way to combine an external ultra-high performance concrete (UHPC) supporting layer with an insulation layer of autoclaved aerated concrete (AAC) or cellular lightweight concrete (CLC) to create light-weight façade elements, which are improved in functionality and in energy efficiency. The durability of the façade elements is improved by developing UHPC with self-cleaning properties. One approach is based on the photocatalytic activation of the external UHPC shell by incorporation of TiO2 particles. The second approach consists of the modification of the UHPC surface by micro structuring in combination with the application of water-repellent agents to create durable super hydrophobicity. The current results obtained from laboratory testing are promising and demonstrate the feasibility of the approaches.