Allergen-specific immunotherapy is an important treatment procedure in IgE-mediated allergic diseases such as allergic rhinitis or insect toxin allergies. A reduction in the clinical reaction to the allergens to which the patient is known to be sensitized is intended by means of antigen-specific influence on the immune system. The allergenspecific immunotherapy can be applied by subcutaneous injections, and for selected allergens by means of sublingual application of the appropriate allergen. Occasionally, the injection of aluminium hydroxide-adsorbed sera induces a usually transient formation of granulomas. We are reporting on a rare case of cutaneous-subcutaneous pseudolymphoma in the injection area of both upper arms, probably induced by subcutaneous allergen-specific immunotherapy.
The aim of this study was to develop a lightweight composite façade element for refurbishment of existing façades. It was crucial to minimize the thermal bridges and to undercut the thermal requirement of the system existing façade new element. The awareness of the environmental impact of the building sector is increasing. In this context, ultra-high performance concrete (UHPC) materials are shown to be promising alternatives with advantages such as lower embodied energy and reduced environmental impact. Predictions suggest that UHPC composite elements for building envelopes could have other benefits such as an increased service life, optimized use of building area due to thinner elements and minimized maintenance due to the absence of reinforcement or use of non-corrosive reinforcing materials such as carbon fibers. In this framework, composite elements have been developed combining an autoclaved aerated concrete insulation layer with an external UHPC supporting layer. The results show that the lightweight composite element has a good performance in term of thermal transmittance and minimization of thermal bridges.