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Structural Eurocodes offer the opportunity of harmonized design standards for the European construction markets and the rest of the world. Eurocodes aim at delivering structures with an appropriate degree of reliability and in an economic way. The reliability requirements of the Eurocodes and the associated background philosophy are discussed in this contribution. The definition and the measure of reliability in standards and especially in the Eurocodes are reviewed. The procedures for selecting target and acceptable re-liability levels are summarized and the reliability differentiation in the Eurocodes is highlighted. Global failure aspects including robustness are briefly discussed. Finally examples from case studies are provided demonstrating the applicability and the benefits from the reliability differentiation approach.