• search hit 5 of 6
Back to Result List

Accurate localization of brain activity in presurgical fMRI by structure adaptive smoothing

Please always quote using this URN:urn:nbn:de:0296-matheon-3420
  • An important problem of the analysis of fMRI experiments is to achieve some noise reduction of the data without blurring the shape of the activation areas. As a novel solution to this problem, the Propagation-Separation approach (PS), a structure adaptive smoothing method, has been proposed recently. PS adapts to different shapes of activation areas by generating a spatial structure corresponding to similarities and differences between time series in adjacent locations. In this paper we demonstrate how this method results in more accurate localization of brain activity. First, it is shown in numerical simulations that PS is superior over Gaussian smoothing with respect to the accurate description of the shape of activation clusters and and results in less false detections. Second, in a study of 37 presurgical planning cases we found that PS and Gaussian smoothing often yield different results, and we present examples showing aspects of the superiority of PS as applied to presurgical planning.

Download full text files

Export metadata

Additional Services

Share in Twitter Search Google Scholar
Metadaten
Author:Karsten Tabelow, Jörg Polzehl, Aziz M. Uluğ, Jonathan P. Dyke, Richard Watts, Linda A. Heier, Henning U. Voss
URN:urn:nbn:de:0296-matheon-3420
Referee:Christof Schütte
Document Type:Preprint, Research Center Matheon
Language:English
Date of first Publication:2006/09/11
Release Date:2006/06/06
Tag:
Institute:Weierstraß-Institut für Angewandte Analysis und Stochastik (WIAS)
MSC-Classification:62-XX STATISTICS / 62Gxx Nonparametric inference / 62G05 Estimation
62-XX STATISTICS / 62Gxx Nonparametric inference / 62G10 Hypothesis testing
62-XX STATISTICS / 62Pxx Applications [See also 90-XX, 91-XX, 92-XX] / 62P10 Applications to biology and medical sciences
92-XX BIOLOGY AND OTHER NATURAL SCIENCES / 92Cxx Physiological, cellular and medical topics / 92C55 Biomedical imaging and signal processing [See also 44A12, 65R10]
Preprint Number:357
Verstanden ✔
Diese Webseite verwendet technisch erforderliche Session-Cookies. Durch die weitere Nutzung der Webseite stimmen Sie diesem zu. Unsere Datenschutzerklärung finden Sie hier.