Resolving the apparent gap in complexity between simulated and measured kinetics of biomolecules
Please always quote using this URN:urn:nbn:de:0296-matheon-11029
- Molecular simulations of biomolecules often reveal a complex picture of the their kinetics, whereas kinetic experiments typically seem to indicate considerably simpler two- or three-state kinetics. Markov state models (MSM) provide a tool to link between simulation and experi- ment, and to resolve this apparent contradiction.
Author: | Bettina Keller, Jan-Hendrik Prinz, Frank Noe |
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URN: | urn:nbn:de:0296-matheon-11029 |
Referee: | Christof Schütte |
Document Type: | Preprint, Research Center Matheon |
Language: | English |
Date of first Publication: | 2012/05/18 |
Release Date: | 2012/05/18 |
Institute: | Research Center Matheon |
Freie Universität Berlin | |
MSC-Classification: | 62-XX STATISTICS / 62Mxx Inference from stochastic processes / 62M05 Markov processes: estimation |
Preprint Number: | 958 |