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We study an extension of the shortest path network interdiction problem and present a novel real-world application in this area. We consider the problem of determining optimal locations for toll control stations on the arcs of a transportation network. We handle the fact that drivers can avoid control stations on parallel secondary roads. The problem is formulated as a mixed integer program and solved using Benders decomposition. We present experimental results for the application of our models to German motorways.
Model-based optimal design of experiments (M-bODE) is a crucial step in model parametrization since it encloses a framework
that maximizes the amount of information extracted from a battery of lab experiments.
We address the design of M-bODE for dynamic models considering a continuous representation of the design.
We use Semidefinite Programming (SDP) to derive robust minmax formulations for nonlinear models,
and extend the formulations to other criteria. The approaches are demonstrated for a CSTR where a two-step reaction occurs.
We prove a mathematical programming characterisation of approximate partial D-optimality under general linear constraints. We use this characterisation with a branch-and-bound method to compute a list of all exact D-optimal designs for estimating a pair of treatment contrasts in the presence of a nuisance time trend up to the size of 24 consecutive trials.