Refine
Year of publication
Document Type
- In Proceedings (40)
- Article (17)
- ZIB-Report (15)
- Book chapter (1)
Is part of the Bibliography
- no (73)
Keywords
- hyperthermia (3)
- 3D Correspondence Problem (1)
- Diffusion Filtering (1)
- Geometric Distortion (1)
- Isoflächen (1)
- Maxwell's equations (1)
- Model-Based Segmentation (1)
- Pelvic heating (1)
- Simplifizierung (1)
- Statistical Shape Model (1)
Institute
Simulation Studies Promote Technological Development of Radiofrequency Phased Array Hyperthermia
(1996)
Simulation studies promote technological development of radiofrequency phased array hyperthermia
(1996)
This paper presents an automatic approach for segmentation of the liver from computer tomography (CT) images based on a 3D statistical shape model. Segmentation of the liver is an important prerequisite in liver surgery planning. One of the major challenges in building a 3D shape model from a training set of segmented instances of an object is the determination of the correspondence between different surfaces. We propose to use a geometric approach that is based on minimizing the distortion of the correspondence mapping between two different surfaces. For the adaption of the shape model to the image data a profile model based on the grey value appearance of the liver and its surrounding tissues in contrast enhanced CT data was developed. The robustness of this method results from a previous nonlinear diffusion filtering of the image data. Special focus is turned to the quantitative evaluation of the segmentation process. Several different error measures are discussed and implemented in a study involving more than 30 livers.
Regional hyperthermia, a clinical cancer therapy, is the main topic of the Sonderforschungsbereich Hyperthermia: Scientific Methods and Clinical Applications'' at Berlin. In recent years, technological improvements towards a better concentration of heat to the desired target region have been achieved. These include a rather sophisticated integrated software environment for therapy planning and a new hyperthermia applicator. In a next step, a detailed closed loop monitoring of the actual treatment is to be developed. For this purpose the hyperthermia applicator is combined with an MRI system, which will allow to check the positioning of the patients and to measure individual blood perfusion as well as the 3D temperature distribution. The measurements will then be employed for an on-line control of the whole treatment. In this intended setting, new fast feedback control algorithms will come into play.