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Geodesic B-Score for Improved Assessment of Knee Osteoarthritis

  • Three-dimensional medical imaging enables detailed understanding of osteoarthritis structural status. However, there remains a vast need for automatic, thus, reader-independent measures that provide reliable assessment of subject-specific clinical outcomes. To this end, we derive a consistent generalization of the recently proposed B-score to Riemannian shape spaces. We further present an algorithmic treatment yielding simple, yet efficient computations allowing for analysis of large shape populations with several thousand samples. Our intrinsic formulation exhibits improved discrimination ability over its Euclidean counterpart, which we demonstrate for predictive validity on assessing risks of total knee replacement. This result highlights the potential of the geodesic B-score to enable improved personalized assessment and stratification for interventions.
Metadaten
Author:Felix AmbellanORCiD, Stefan ZachowORCiD, Christoph von TycowiczORCiD
Document Type:In Proceedings
Parent Title (English):Proc. Information Processing in Medical Imaging (IPMI)
First Page:177
Last Page:188
Series:Lecture Notes in Computer Science
Year of first publication:2021
ArXiv Id:http://arxiv.org/abs/2104.01107
Preprint:urn:nbn:de:0297-zib-81930
DOI:https://doi.org/10.1007/978-3-030-78191-0_14
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