Mathematical modeling of follicular development in bovine estrous cycles
Please always quote using this URN: urn:nbn:de:0297-zib-15585
- Normal follicular growth is a prerequisite for successful fertilization of dairy cows. However, submission rates have been decreasing during the last decades because animals are not ovulating at the planned time of mating or insemination. In this study we use a mathematical model to investigate mechanisms that lead to anestrus. This model is derived by coupling two previously published models: a small model for the development of multiple follicles (Smith et al., 2004), and a large estrous cycle model (St\"otzel et al., 2012). We first investigate the influence of synchronization protocols on the time-shift of ovulation. In a second scenario we simulate an extended period of anestrus as it typically occurs after calving.
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| Author: | Manon Bondouy, Susanna RöblitzORCiD |
|---|---|
| Document Type: | ZIB-Report |
| Tag: | dairy cows; ordinary differential equations; reproduction; systems biology |
| MSC-Classification: | 90-XX OPERATIONS RESEARCH, MATHEMATICAL PROGRAMMING / 90Cxx Mathematical programming [See also 49Mxx, 65Kxx] / 90C31 Sensitivity, stability, parametric optimization |
| 92-XX BIOLOGY AND OTHER NATURAL SCIENCES / 92Cxx Physiological, cellular and medical topics / 92C30 Physiology (general) | |
| 92-XX BIOLOGY AND OTHER NATURAL SCIENCES / 92Cxx Physiological, cellular and medical topics / 92C42 Systems biology, networks | |
| 93-XX SYSTEMS THEORY; CONTROL (For optimal control, see 49-XX) / 93Axx General / 93A30 Mathematical modeling (models of systems, model-matching, etc.) | |
| Date of first Publication: | 2012/07/27 |
| Series (Serial Number): | ZIB-Report (12-26) |
| ISSN: | 1438-0064 |
