TY - CHAP A1 - Poethke, Jens A1 - Goubergrits, Leonid A1 - Kertzscher, Ulrich A1 - Spuler, Andreas A1 - Petz, Christoph A1 - Hege, Hans-Christian ED - Jos Vander Sloten, Pascal ED - Haueisen, Jens T1 - Impact of imaging modality for analysis of a cerebral aneurysm: Comparison between CT, MRI and 3DRA T2 - Proceedings of the 4th European Conference of the International Federation for Medical and Biological Engineering Y1 - 2008 U6 - https://doi.org/10.1007/978-3-540-89208-3 SP - 1889 EP - 1893 PB - Springer-Verlag CY - Antwerp, Belgium ER - TY - JOUR A1 - Heller, Markus O. A1 - Matziolis, Georg A1 - König, Christian A1 - Taylor, William R. A1 - Hinterwimmer, S. A1 - Graichen, H. A1 - Hege, Hans-Christian A1 - Bergmann, G. A1 - Perka, Carsten A1 - Duda, G. N. T1 - Muskuloskelettale Biomechanik des Kniegelenks - Grundlagen für die präoperative Planung von Umstellung und Gelenkersatz JF - Der Orthopäde Y1 - 2007 U6 - https://doi.org/10.1007/s00132-007-1115-2 VL - 36 IS - 7 SP - 628 EP - 634 ER - TY - CHAP A1 - Kähler, Ralf A1 - Abel, Tom A1 - Hege, Hans-Christian T1 - Simultaneous GPU-Assisted Raycasting of Unstructured Point Sets and Volumetric Grid Data T2 - Proceedings of IEEE/EG International Symposium on Volume Graphics 2007 Y1 - 2007 SP - 49 EP - 56 PB - A K Peters CY - Prague, Czech Republic ER - TY - GEN A1 - Oberlaender, Marcel A1 - Dercksen, Vincent J. A1 - Lang, Stefan A1 - Sakmann, Bert T1 - 3D mapping of synaptic connections within “in silico” microcircuits of full compartmental neurons in extended networks on the example of VPM axons projecting into S1 of rats. T2 - Conference Abstract, Neuroinformatics Y1 - 2009 U6 - https://doi.org/10.3389/conf.neuro.11.2009.08.092 ER - TY - GEN A1 - Oberlaender, Marcel A1 - Bruno, Randy M. A1 - de Kock, Christiaan P. J. A1 - Meyer, Hanno A1 - Dercksen, Vincent J. A1 - Sakmann, Bert T1 - 3D distribution and sub-cellular organization of thalamocortical VPM synapses for individual excitatory neuronal cell types in rat barrel cortex T2 - Conference Abstract No. 173.19/Y35, 39th Annual Meeting of the Society for Neuroscience (SfN) Y1 - 2009 ER - TY - CHAP A1 - Homberg, Ulrike A1 - Binner, Richard A1 - Prohaska, Steffen A1 - Dercksen, Vincent J. A1 - Kuß, Anja A1 - Kalbe, Ute T1 - Determining Geometric Grain Structure from X-Ray Micro-Tomograms of Gradated Soil T2 - Workshop Internal Erosion Y1 - 2009 VL - 21 SP - 37 EP - 52 ER - TY - GEN A1 - Oberlaender, Marcel A1 - Dercksen, Vincent J. A1 - Broser, Philip J. A1 - Bruno, Randy M. A1 - Sakmann, Bert T1 - NeuroMorph and NeuroCount: Automated tools for fast and objective acquisition of neuronal morphology for quantitative structural analysis T2 - Frontiers in Neuroinformatics. Conference Abstract: Neuroinformatics Y1 - 2008 U6 - https://doi.org/10.3389/conf.neuro.11.2008.01.065 ER - TY - JOUR A1 - Laramee, Robert S. A1 - Erlebacher, Gordon A1 - Garth, Christoph A1 - Schafhitzel, Tobias A1 - Theisel, Holger A1 - Tricoche, Xavier A1 - Weinkauf, Tino A1 - Weiskopf, Daniel T1 - Applications of Texture-Based Flow Visualization JF - Engineering Applications of Computational Fluid Mechanics Y1 - 2008 UR - http://www.cs.swan.ac.uk/~csbob/research/application/ VL - 2 IS - 3 SP - 264 EP - 274 ER - TY - JOUR A1 - Petz, Christoph A1 - Kasten, Jens A1 - Prohaska, Steffen A1 - Hege, Hans-Christian T1 - Hierarchical Vortex Regions in Swirling Flow JF - Computer Graphics Forum Y1 - 2009 VL - 28 IS - 3 SP - 863 EP - 870 ER - TY - CHAP A1 - Dercksen, Vincent J. A1 - Weber, Britta A1 - Günther, David A1 - Oberlaender, Marcel A1 - Prohaska, Steffen A1 - Hege, Hans-Christian T1 - Automatic alignment of stacks of filament data T2 - Proc. IEEE International Symposium on Biomedical Imaging Y1 - 2009 SP - 971 EP - 974 PB - IEEE press CY - Boston, USA ER - TY - CHAP A1 - Rosanwo, Olufemi A1 - Petz, Christoph A1 - Prohaska, Steffen A1 - Hotz, Ingrid A1 - Hege, Hans-Christian ED - Eades, Peter ED - Ertl, Thomas ED - Shen, Han-Wei T1 - Dual Streamline Seeding T2 - Proceedings of the IEEE Pacific Visualization Symposium Y1 - 2009 SP - 9 EP - 16 CY - Beijing, China ER - TY - CHAP A1 - Rybak, Jürgen A1 - Kuß, Anja A1 - Holler, Wolfgang A1 - Brandt, Robert A1 - Hege, Hans-Christian A1 - Menzel, Randolf T1 - The HoneyBee Standard Brain (HSB) - a versatile atlas tool for integrating data and data exchange in the neuroscience community T2 - BMC Neuroscience Y1 - 2009 U6 - https://doi.org/10.1186/1471-2202-10-S1-P1 VL - 10 (Suppl 1):P1 ER - TY - JOUR A1 - Oberlaender, Marcel A1 - Dercksen, Vincent J. A1 - Egger, Robert A1 - Gensel, Maria A1 - Sakmann, Bert A1 - Hege, Hans-Christian T1 - Automated three-dimensional detection and counting of neuron somata JF - Journal of Neuroscience Methods Y1 - 2009 U6 - https://doi.org/10.1016/j.jneumeth.2009.03.008 VL - 180 IS - 1 SP - 147 EP - 160 ER - TY - CHAP A1 - Kasten, Jens A1 - Weinkauf, Tino A1 - Petz, Christoph A1 - Hotz, Ingrid A1 - Noack, Bernd R. A1 - Hege, Hans-Christian T1 - Extraction of Coherent Structures from Natural and Actuated Flows T2 - Active Flow Control II Y1 - 2010 SN - 978-3-642-11734-3 U6 - https://doi.org/10.1007/978-3-642-11735-0_24 VL - 108 SP - 373 EP - 387 PB - Springer, Berlin ER - TY - JOUR A1 - Otto, Mathias A1 - Germer, Tobias A1 - Hege, Hans-Christian A1 - Theisel, Holger T1 - Uncertain 2D Vector Field Topology JF - Comput. Graph. Forum Y1 - 2010 U6 - https://doi.org/10.1111/j.1467-8659.2009.01604.x VL - 29 SP - 347 EP - 356 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Thamsen, Bente A1 - Berthe, André A1 - Poethke, Jens A1 - Kertzscher, Ulrich A1 - Affeld, Klaus A1 - Petz, Christoph A1 - Hege, Hans-Christian A1 - Hoch, Heinrich A1 - Spuler, Andreas T1 - In Vitro Study of Near-Wall Flow in a Cerebral Aneurysm Model with and without Coils JF - American Journal of Neuroradiology Y1 - 2010 U6 - https://doi.org/10.3174/ajnr.A2121 VL - 31:8 SP - 1521 EP - 1528 ER - TY - JOUR A1 - Hege, Hans-Christian A1 - Laidlaw, David A1 - Machiraju, Raghu T1 - Guest Editor's Introduction: Special Section on Volume Graphics and Point-Based Graphics JF - IEEE Trans. Vis. Comput. Graph. Y1 - 2010 U6 - https://doi.org/10.1109/TVCG.2010.72 VL - 16 IS - 4 SP - 531 EP - 532 ER - TY - CHAP A1 - Hege, Hans-Christian A1 - Hotz, Ingrid A1 - Munzner, Tamara T1 - Euro Vis 2009 - Eurographics/IEEE-VGTC Symposium on Visualization T2 - Comput. Graphics. Forum Y1 - 2009 N1 - Preface of Proceedings VL - 28 ER - TY - CHAP A1 - Kuß, Anja A1 - Prohaska, Steffen A1 - Meyer, Björn A1 - Rybak, Jürgen A1 - Hege, Hans-Christian T1 - Ontology-Based Visualization of Hierarchical Neuroanatomical Structures T2 - Proceedings of the Eurographics Workshop on Visual Computing for Biomedicine VCBM 2008 Y1 - 2008 SP - 177 EP - 184 ER - TY - JOUR A1 - Shi, Kuangyu A1 - Weinkauf, Tino A1 - Theisel, Holger A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Visualizing Transport Structures of Time-Dependent Flow Fields JF - IEEE Computer Graphics and Applications Y1 - 2008 U6 - https://doi.org/10.1109/MCG.2008.106 SP - 24 EP - 35 ER - TY - CHAP A1 - von Funck, Wolfram A1 - Weinkauf, Tino A1 - Theisel, Holger A1 - Hege, Hans-Christian T1 - Smoke Surfaces: An Interactive Flow Visualization Technique Inspired by Real-World Flow Experiments T2 - IEEE Transactions on Visualization and Computer Graphics (Proceedings Visualization 2008) Y1 - 2008 U6 - https://doi.org/10.1109/TVCG.2008.163 VL - 14 IS - 6 SP - 1396 EP - 1403 ER - TY - CHAP A1 - Papazov, Chavdar A1 - Dercksen, Vincent J. A1 - Lamecker, Hans A1 - Hege, Hans-Christian T1 - Visualizing morphogenesis and growth by temporal interpolation of surface-based 3D atlases T2 - Proceedings of the 2008 IEEE International Symposium on Biomedical Imaging Y1 - 2008 U6 - https://doi.org/10.1109/ISBI.2008.4541123 SP - 824 EP - 827 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Kertzscher, Ulrich A1 - Schöneberg, Bastian A1 - Wellnhofer, Ernst A1 - Petz, Christoph T1 - CFD analysis in an anatomically realistic coronary artery model based on non-invasive 3D imaging JF - Int. J. Cardiovasc. Imaging Y1 - 2008 U6 - https://doi.org/10.1007/s10554-007-9275-z VL - 24(4) SP - 411 EP - 421 ER - TY - CHAP A1 - Petz, Christoph A1 - Prohaska, Steffen A1 - Goubergrits, Leonid A1 - Kertzscher, Ulrich A1 - Hege, Hans-Christian T1 - Near-Wall Flow Visualization in Flattened Surface Neighborhoods T2 - Proc. Simulation and Visualization 2008 Y1 - 2008 UR - http://www.simvis.org/Tagung2008/sv-proceedings.html SP - 93 EP - 105 CY - Magdeburg, Germany ER - TY - JOUR A1 - Sahner, Jan A1 - Weber, Britta A1 - Lamecker, Hans A1 - Prohaska, Steffen T1 - Extraction of feature Lines on surface meshes based on discrete Morse theory JF - Computer Graphics Forum Y1 - 2008 U6 - https://doi.org/10.1111/j.1467-8659.2008.01202.x VL - 27 IS - 3 SP - 735 EP - 742 CY - Eindhoven, Netherlands ER - TY - CHAP A1 - Shi, Kuangyu A1 - Theisel, Holger A1 - Weinkauf, Tino A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Finite-Time Transport Structures of Flow Fields T2 - Proc. IEEE Pacific Visualization 2008 Y1 - 2008 U6 - https://doi.org/10.1109/PACIFICVIS.2008.4475460 SP - 63 EP - 70 CY - Kyoto, Japan ER - TY - CHAP A1 - Weinkauf, Tino A1 - Sahner, Jan A1 - Günther, Bert A1 - Theisel, Holger A1 - Hege, Hans-Christian A1 - Thiele, Frank T1 - Feature-based Analysis of a Multi-Parameter Flow Simulation T2 - Proc. of 19th Simulation and Visualization Conference (SimVis 2008) Y1 - 2008 SP - 237 EP - 251 CY - Magdeburg, Germany ER - TY - GEN A1 - Shi, Kuangyu A1 - Theisel, Holger A1 - Weinkauf, Tino A1 - Hauser, Helwig A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Extracting separation surfaces of path line oriented topology in periodic 2D time-dependent vector fields Y1 - 2007 SP - 75 EP - 82 ER - TY - CHAP A1 - Shi, Kuangyu A1 - Theisel, Holger A1 - Hauser, Helwig A1 - Weinkauf, Tino A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Path Line Attributes - an Information Visualization Approach to Analyzing the Dynamic Behavior of 3D Time-Dependent Flow Fields T2 - Topology-Based Methods in Visualization II Y1 - 2009 U6 - https://doi.org/10.1007/978-3-540-88606-8_6 SP - 75 EP - 88 PB - Springer CY - Berlin ER - TY - CHAP A1 - Kuß, Anja A1 - Hege, Hans-Christian A1 - Krofczik, Sabine A1 - Börner, Jana T1 - Pipeline for the creation of surface-based averaged brain atlases T2 - Proceedings of WSCG 2007 - the 15-th International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision Y1 - 2007 VL - 15 SP - 17 EP - 24 CY - Plzen, Czech Republic ER - TY - GEN A1 - Sahner, Jan A1 - Weinkauf, Tino A1 - Teuber, Nathalie A1 - Hege, Hans-Christian T1 - Vortex and strain skeletons in Eulerian and Lagrangian frames Y1 - 2007 U6 - https://doi.org/10.1109/TVCG.2007.1053 SP - 980 EP - 990 ER - TY - CHAP A1 - Weinkauf, Tino A1 - Theisel, Holger A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Feature Flow Fields in Out-of-Core Settings T2 - Topology-based Methods in Visualization Y1 - 2007 SP - 51 EP - 64 PB - Springer ER - TY - JOUR A1 - Weinkauf, Tino A1 - Sahner, Jan A1 - Theisel, Holger A1 - Hege, Hans-Christian T1 - Cores of Swirling Particle Motion in Unsteady Flows JF - IEEE Transactions on Visualization and Computer Graphics (Proceedings Visualization 2007) Y1 - 2007 U6 - https://doi.org/10.1109/TVCG.2007.70545 VL - 13 IS - 6 SP - 1759 EP - 1766 ER - TY - CHAP A1 - Günther, Bert A1 - Thiele, Frank A1 - Petz, Ralf A1 - Nitsche, Wolfgang A1 - Sahner, Jan A1 - Weinkauf, Tino A1 - Hege, Hans-Christian T1 - Control of Separation on the Flap of a Three-Element High-Lift Configuration T2 - 45th AIAA Aerospace Sciences Meeting and Exhibit Y1 - 2007 CY - Reno, NV, U.S.A. ER - TY - CHAP A1 - Kasten, Jens A1 - Petz, Christoph A1 - Hotz, Ingrid A1 - Noack, Bernd R. A1 - Hege, Hans-Christian ED - Magnor, Marcus ED - Rosenhahn, Bodo ED - Theisel, Holger T1 - Localized Finite-time Lyapunov Exponent for Unsteady Flow Analysis T2 - Vision Modeling and Visualization Y1 - 2009 SN - 978-3-9804874-8-1 VL - 1 SP - 265 EP - 274 PB - Universität Magdeburg, Inst. f. Simulation u. Graph. ER - TY - CHAP A1 - Kuß, Anja A1 - Prohaska, Steffen A1 - Rybak, Jürgen T1 - Using Ontologies for the Visualization of Hierarchical Neuroanatomical Structures T2 - Frontiers in Neuroinformatics. Conference Abstract: 2nd INCF Congress of Neuroinformatics Y1 - 2009 U6 - https://doi.org/10.3389/conf.neuro.11.2009.08.017 ER - TY - CHAP A1 - Kuß, Anja A1 - Hege, Hans-Christian T1 - Knowledge Representation for Digital Atlases T2 - Conference Abstracts: Workshop of the Working Group 'Ontologies in Biomedicine and the Life Science' Y1 - 2009 PB - Max-Planck Institute for Evolutionary Anthropology CY - Leipzig ER - TY - GEN A1 - Dercksen, Vincent J. A1 - Gensel, Maria A1 - Kuß, Anja T1 - Visual Accentuation of Spatial Relationships between Filamentous and Voluminous Surface Structures T2 - Conference Abstract, Eurographics / IEEE Symposium on Visualization Y1 - 2009 ER - TY - JOUR A1 - Barth, Ingo A1 - Hege, Hans-Christian A1 - Ikeda, Hiroshi A1 - Kenfack, Anatole A1 - Koppitz, Michael A1 - Manz, Jörn A1 - Marquardt, Falko A1 - K. Paramonov, Guennaddi T1 - Concerted Quantum Effects of Electronic and Nuclear Fluxes in Molecules JF - Chem. Phys. Lett. Y1 - 2009 U6 - https://doi.org/10.1016/j.cplett.2009.09.011 VL - 481 IS - 1-3 SP - 118 EP - 123 PB - Elsevier ER - TY - JOUR A1 - Alonso, Sergio A1 - Kähler, Ralf A1 - S. Mikhailov, Alexander A1 - Sagués, Francisco T1 - Expanding scroll rings and negative tension turbulence in a model of excitable media JF - Phys. Rev. E Y1 - 2004 U6 - https://doi.org/10.1103/PhysRevE.70.056201 VL - 70 IS - 5 SP - 056201 PB - American Physical Society ER - TY - CHAP A1 - Theisel, Holger A1 - Weinkauf, Tino A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Grid-independent detection of closed stream lines in 2D vector fields T2 - Proc. Vision, Modeling and Visualization 2004 Y1 - 2004 SP - 421 EP - 428 CY - Stanford, U.S.A. ER - TY - CHAP A1 - Theisel, Holger A1 - Weinkauf, Tino T1 - On the Applicability of Topological Methods for Complex Flow Data T2 - Topology-based Methods in Visualization Y1 - 2007 U6 - https://doi.org/10.1007/978-3-540-70823-0_8 SP - 105 EP - 120 PB - Springer ER - TY - CHAP A1 - Weinkauf, Tino A1 - Sahner, Jan A1 - Theisel, Holger A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - A unified feature extraction architecture T2 - Active Flow Control Y1 - 2007 U6 - https://doi.org/10.1007/978-3-540-71439-2_8 SP - 119 EP - 133 PB - Springer Berlin/Heidelberg ER - TY - JOUR A1 - Gubatz, Sabine A1 - Dercksen, Vincent J. A1 - Brüß, Cornelia A1 - Weschke, Winfriede A1 - Wobus, Ulrich T1 - Analysis of barley (hordeum vulgare) grain development using three-dimensional digital models JF - The Plant Journal Y1 - 2007 U6 - https://doi.org/10.1111/j.1365-313X.2007.03260.x VL - 52 IS - 4 SP - 779 EP - 790 ER - TY - CHAP A1 - Duffy, Alex A1 - Harris, Stefan A1 - Marzi, Jochen A1 - Petz, Christoph A1 - Wu, Zichao T1 - VIRTUE: Integrating CFD Ship Design T2 - Proc. of 7th International Conference on Hydrodynamics Y1 - 2006 ER - TY - CHAP A1 - Kähler, Ralf A1 - Wise, John A1 - Abel, Tom A1 - Hege, Hans-Christian T1 - A framework for interactive, high-quality volume rendering of cosmological simulations T2 - Proc. Int. Workshop on Volume Graphics (VG06) Y1 - 2006 SP - 103 EP - 110 PB - Eurographics / IEEE VGTC 2006 CY - Boston ER - TY - JOUR A1 - Brandt, Robert A1 - Rohlfing, Torsten A1 - Rybak, Jürgen A1 - Krofczik, Sabine A1 - Maye, Alexander A1 - Westerhoff, Malte A1 - Hege, Hans-Christian A1 - Menzel, Randolf T1 - A three-dimensional average-shape atlas of the honeybee brain and its applications JF - Journal of Comparative Neurology Y1 - 2005 VL - 492(1) SP - 1 EP - 19 ER - TY - GEN A1 - Stalling, Detlev A1 - Westerhoff, Malte A1 - Hege, Hans-Christian ED - Hansen, Charles ED - Johnson, Christopher T1 - Amira: A highly interactive system for visual data analysis T2 - The Visualization Handbook Y1 - 2005 U6 - https://doi.org/10.1016/B978-012387582-2/50040-X SP - 749 EP - 767 PB - Elsevier ER - TY - JOUR A1 - Theisel, Holger A1 - Weinkauf, Tino A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Topological methods for 2D time-dependent vector fields based on stream lines and path lines JF - IEEE Transactions on Visualization and Computer Graphics Y1 - 2005 U6 - https://doi.org/10.1109/TVCG.2005.68 VL - 11 IS - 4 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Timmel, Tobias A1 - Affeld, Klaus A1 - Petz, Christoph A1 - Stalling, Detlev A1 - Hege, Hans-Christian T1 - Characterization of an artificial valve flow using the numerical dye washout visualization technique JF - Artificial Organs Y1 - 2006 VL - 30(8) SP - 642 EP - 650 ER - TY - CHAP A1 - Baum, Daniel A1 - Hege, Hans-Christian T1 - A Point-matching based algorithm for 3D surface alignment of drug-sized molecules T2 - Computational Life Sciences II, Second International Symposium, CompLife 2006, Cambridge (UK), Sept. 2006 Y1 - 2006 U6 - https://doi.org/10.1007/11875741_18 VL - 4216 SP - 183 EP - 193 PB - Springer ER - TY - CHAP A1 - Shi, Kuangyu A1 - Theisel, Holger A1 - Weinkauf, Tino A1 - Hauser, Helwig A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Path line oriented topology for periodic 2D time-dependent vector fields T2 - Proc. Eurographics / IEEE VGTC Symposium on Visualization Y1 - 2006 SP - 139 EP - 146 CY - Lisbon, Portugal ER - TY - JOUR A1 - Weinkauf, Tino A1 - Theisel, Holger A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Topological structures in two-parameter-dependent 2D vector fields JF - Computer Graphics Forum Y1 - 2006 U6 - https://doi.org/10.1111/j.1467-8659.2006.00980.x VL - 25 (3) SP - 607 EP - 616 ER - TY - CHAP A1 - Coconu, Liviu A1 - Deussen, Oliver A1 - Hege, Hans-Christian T1 - Real-time pen-and-ink illustration of landscapes T2 - NPAR '06: Proceedings of the 3rd International Symposium on Non-photorealistic Animation and Rendering Y1 - 2006 U6 - https://doi.org/10.1145/1124728.1124734 SP - 27 EP - 35 PB - ACM press CY - New York, NY, USA ER - TY - CHAP A1 - Kähler, Ralf A1 - Prohaska, Steffen A1 - Hutanu, Andrei A1 - Hege, Hans-Christian T1 - Visualization of time-dependent remote adaptive mesh refinement data T2 - Proc. IEEE Visualization 2005 Y1 - 2005 U6 - https://doi.org/10.1109/VISUAL.2005.1532793 SP - 175 EP - 182 CY - Minneapolis, USA ER - TY - CHAP A1 - Weinkauf, Tino A1 - Theisel, Holger A1 - Shi, Kuangyu A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Topological simplification of 3D vector fields and extracting higher order critical points T2 - Proc. IEEE Visualization 2005 Y1 - 2005 SP - 631 EP - 638 CY - Minneapolis, USA ER - TY - CHAP A1 - Sahner, Jan A1 - Weinkauf, Tino A1 - Hege, Hans-Christian ED - Brodlie, K. ED - Duke, D. ED - Joy, K. T1 - Galilean invariant extraction and iconic representation of vortex core lines T2 - Proc. Eurographics / IEEE VGTC Symposium on Visualization (EuroVis ’05) Y1 - 2005 U6 - https://doi.org/10.2312/VisSym/EuroVis05/151-160 SP - 151 EP - 160 CY - Leeds, UK ER - TY - CHAP A1 - Theisel, Holger A1 - Sahner, Jan A1 - Weinkauf, Tino A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Extraction of parallel vector surfaces in 3D time-dependent fields and application to vortex core line tracking T2 - Proc. IEEE Visualization 2005 Y1 - 2005 SP - 559 EP - 566 CY - Minneapolis, USA ER - TY - GEN A1 - Petz, Christoph A1 - Weinkauf, Tino A1 - Streckwall, Heinrich A1 - Salvatore, Franceso A1 - Noack, Bernd R. A1 - Hege, Hans-Christian T1 - Vortex Structures at a Rotating Ship Propeller Y1 - 2006 PB - Presented at the 24th Annual Gallery of Fluid Motion exhibit, held at the 59th Annual Meeting of the American Physical Society, Division of Fluid Dynamics, Tampa Bay ER - TY - JOUR A1 - Ziegler, Günter M. A1 - Hege, Hans-Christian A1 - Duda, Georg T1 - Neue Bilder für die Medizin? JF - DFN-Mitteilungen Y1 - 2005 VL - 13(3) SP - 163 EP - 167 ER - TY - GEN A1 - Hege, Hans-Christian T1 - Hintergrundinformationen zum Artikel ‘Neue Bilder für die Medizin?’ Y1 - 2005 PB - DFG-Research Center Matheon, Report, 19 pages ER - TY - CHAP A1 - Deussen, Oliver A1 - Colditz, Carsten A1 - Coconu, Liviu A1 - Hege, Hans-Christian ED - Bishop, Ian ED - Lange, Eckart T1 - Efficient modelling and rendering of landscapes T2 - Visualization in Landscape and Environmental Planning Y1 - 2005 SP - 56 EP - 61 PB - Spon Press CY - London ER - TY - CHAP A1 - Baum, Daniel T1 - Multiple semi-flexible 3D superposition of drug-sized molecules T2 - Computational Life Sciences: First International Symposium, CompLife 2005 Y1 - 2005 U6 - https://doi.org/10.1007/11560500_18 VL - 3695 SP - 198 EP - 207 PB - Springer CY - Konstanz, Germany ER - TY - CHAP A1 - Colditz, Carsten A1 - Coconu, Liviu A1 - Deussen, Oliver A1 - Hege, Hans-Christian ED - Buhmann, Erich ED - Paar, Philip ED - Bishop, Ian ED - Lange, Eckart T1 - Real-time rendering of complex photorealistic landscapes using hybrid level-of-detail approaches T2 - Trends in Real-Time Landscape Visualization and Participation Y1 - 2005 SP - 97 EP - 106 PB - Wichmann Verlag ER - TY - CHAP A1 - Coconu, Liviu A1 - Colditz, Carsten A1 - Hege, Hans-Christian A1 - Deussen, Oliver ED - Buhmann, Erich ED - Paar, Philip ED - Bishop, Ian ED - Lange, Eckart T1 - Seamless integration of stylized renditions in computer-generated landscape visualization T2 - Trends in Real-Time Landscape Visualization and Participation Y1 - 2005 SP - 88 EP - 96 PB - Wichmann Verlag CY - Heidelberg ER - TY - CHAP A1 - Clasen, Malte A1 - Hege, Hans-Christian ED - Buhmann, Erich ED - Paar, Philip ED - Bishop, Ian ED - Lange, Eckart T1 - Realistic illumination of vegetation in real-time environments T2 - Trends in Real-Time Landscape Visualization and Participation Y1 - 2005 SP - 107 EP - 114 PB - Wichmann Verlag ER - TY - JOUR A1 - Werner, Armin A1 - Deussen, Oliver A1 - Döllner, Jürgen A1 - Hege, Hans-Christian A1 - Paar, Philip A1 - Rekittke, Jörg ED - Buhmann, Erich ED - Paar, Philip ED - Bishop, Ian ED - Lange, Eckart T1 - Lenné 3D walking through landscape plan JF - Trends in Real-Time Landscape Visualization and Participation Y1 - 2005 SP - 48 EP - 59 PB - Wichmann Verlag ER - TY - JOUR A1 - Hildebrandt, Klaus A1 - Schulz, Christian A1 - Tycowicz, Christoph von A1 - Polthier, Konrad T1 - Interactive spacetime control of deformable objects JF - ACM Transactions on Graphics N2 - Creating motions of objects or characters that are physically plausible and follow an animator’s intent is a key task in computer animation. The spacetime constraints paradigm is a valuable approach to this problem, but it suffers from high computational costs. Based on spacetime constraints, we propose a technique that controls the motion of deformable objects and offers an interactive response. This is achieved by a model reduction of the underlying variational problem, which combines dimension reduction, multipoint linearization, and decoupling of ODEs. After a preprocess, the cost for creating or editing a motion is reduced to solving a number of one-dimensional spacetime problems, whose solutions are the wiggly splines introduced by Kass and Anderson [2008]. We achieve interactive response using a new fast and robust numerical scheme for solving a set of one-dimensional problems based on an explicit representation of the wiggly splines. Y1 - 2012 U6 - https://doi.org/10.1145/2185520.2185567 VL - 31 IS - 4 SP - 71:1 EP - 71:8 PB - ACM ER - TY - CHAP A1 - Greenhalgh, Chris A1 - Benford, Steve A1 - Drozd, Adam A1 - Flintham, Martin A1 - Hampshire, Alastair A1 - Oppermann, Leif A1 - Smith, Keir A1 - Tycowicz, Christoph von T1 - EQUIP2: A Platform for Mobile Phone-based Game Development T2 - Concepts and Technologies for Pervasive Games - A Reader for Pervasive Gaming Research Y1 - 2007 SN - 978-3-8322-6223-5 VL - 1 SP - 153 EP - 178 PB - Shaker Verlag ER - TY - JOUR A1 - Egger, Robert A1 - Dercksen, Vincent J. A1 - Udvary, Daniel A1 - Hege, Hans-Christian A1 - Oberlaender, Marcel T1 - Generation of dense statistical connectomes from sparse morphological data JF - Frontiers in Neuroanatomy Y1 - 2014 U6 - https://doi.org/10.3389/fnana.2014.00129 VL - 8 IS - 129 ER - TY - GEN A1 - Lindow, Norbert A1 - Baum, Daniel A1 - Hege, Hans-Christian T1 - Ligand Excluded Surface: A New Type of Molecular Surface N2 - The most popular molecular surface in molecular visualization is the solvent excluded surface (SES). It provides information about the accessibility of a biomolecule for a solvent molecule that is geometrically approximated by a sphere. During a period of almost four decades, the SES has served for many purposes – including visualization, analysis of molecular interactions and the study of cavities in molecular structures. However, if one is interested in the surface that is accessible to a molecule whose shape differs significantly from a sphere, a different concept is necessary. To address this problem, we generalize the definition of the SES by replacing the probe sphere with the full geometry of the ligand defined by the arrangement of its van der Waals spheres. We call the new surface ligand excluded surface (LES) and present an efficient, grid-based algorithm for its computation. Furthermore, we show that this algorithm can also be used to compute molecular cavities that could host the ligand molecule. We provide a detailed description of its implementation on CPU and GPU. Furthermore, we present a performance and convergence analysis and compare the LES for several molecules, using as ligands either water or small organic molecules. T3 - ZIB-Report - 14-27 Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-51194 SN - 1438-0064 ER - TY - CHAP A1 - Pfister, Hanspeter A1 - Kaynig, Verena A1 - Botha, Charl P. A1 - Bruckner, Stefan A1 - Dercksen, Vincent J. A1 - Hege, Hans-Christian A1 - Roerdink, Jos B.T.M. ED - Hansen, Charles D. ED - Chen, Min ED - Johnson, Christopher R. ED - Kaufman, Arie E. ED - Hagen, Hans T1 - Visualization in Connectomics T2 - Scientific Visualization - Uncertainty, Multifield, Biomedical, and Scalable Visualization N2 - Connectomics is a branch of neuroscience that attempts to create a connectome, i.e., a complete map of the neuronal system and all connections between neuronal structures. This representation can be used to understand how functional brain states emerge from their underlying anatomical structures and how dysfunction and neuronal diseases arise. We review the current state-of-the-art of visualization and image processing techniques in the field of connectomics and describe a number of challenges. After a brief summary of the biological background and an overview of relevant imaging modalities, we review current techniques to extract connectivity information from image data at macro-, meso- and microscales. We also discuss data integration and neural network modeling, as well as the visualization, analysis and comparison of brain networks. Y1 - 2014 SN - 978-1-4471-6496-8 U6 - https://doi.org/10.1007/978-1-4471-6497-5_21 SP - 221 EP - 245 PB - Springer ER - TY - CHAP A1 - Bonneau, Georges-Pierre A1 - Hege, Hans-Christian A1 - Johnson, Chris R. A1 - Oliveira, Manuel M. A1 - Potter, Kristin A1 - Rheingans, Penny A1 - Schultz, Thomas T1 - Overview and State-of-the-Art of Uncertainty Visualization T2 - Scientific Visualization - Uncertainty, Multifield, Biomedical, and Scalable Visualization N2 - The goal of visualization is to effectively and accurately communicate data. Visualization research has often overlooked the errors and uncertainty which accompany the scientific process and describe key characteristics used to fully understand the data. The lack of these representations can be attributed, in part, to the inherent difficulty in defining, characterizing, and controlling this uncertainty, and in part, to the difficulty in including additional visual metaphors in a well designed, potent display. However, the exclusion of this information cripples the use of visualization as a decision making tool due to the fact that the display is no longer a true representation of the data. This systematic omission of uncertainty commands fundamental research within the visualization community to address, integrate, and expect uncertainty information. In this chapter, we outline sources and models of uncertainty, give an overview of the state-of-the-art, provide general guidelines, outline small exemplary applications, and finally, discuss open problems in uncertainty visualization. Y1 - 2014 SN - 978-1-4471-6496-8 U6 - https://doi.org/10.1007/978-1-4471-6497-5_1 SP - 3 EP - 27 PB - Springer ER - TY - GEN ED - Linsen, Lars ED - Hagen, Hans ED - Hamann, Bernd ED - Hege, Hans-Christian T1 - Visualization in Medicine and Life Sciences II Y1 - 2012 SN - 978-3-642-21607-7 U6 - https://doi.org/10.1007/978-3-642-21608-4 PB - Springer CY - Berlin ER - TY - THES A1 - von Hafe Pérez Ferreira da Silva, Maria Isabel T1 - Computational Left-Ventricle Reconstruction from MRI Data for Patient-specific Cardiac Simulations Y1 - 2014 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Spuler, Andreas A1 - Schaller, Jens A1 - Wiegmann, Nils A1 - Berthe, Andre A1 - Hege, Hans-Christian A1 - Affeld, Klaus A1 - Kertzscher, Ulrich T1 - In vitro study of hemodynamic treatment improvement: Hunterian ligation of a fenestrated basilar artery aneurysm after coiling JF - The International Journal of Artificial Organs N2 - Hunterian ligation affecting hemodynamics in vessels was proposed to avoid rebleeding in a case of a fenestrated basilar artery aneurysm after incomplete coil occlusion. We studied the hemodynamics in vitro to predict the hemodynamic changes near the aneurysm remnant caused by Hunterian ligation. A transparent model was fabricated based on three-dimensional rotational angiography imaging. Arteries were segmented and reconstructed. Pulsatile flow in the artery segments near the partially occluded (coiled) aneurysm was investigated by means of particle image velocimetry. The hemodynamic situation was investigated before and after Hunterian ligation of either the left or the right vertebral artery (LVA/RVA). Since post-ligation flow rate in the basilar artery was unknown, reduced and retained flow rates were simulated for both ligation options. Flow in the RVA and in the corresponding fenestra vessel is characterized by a vortex at the vertebrobasilar junction, whereas the LVA exhibits undisturbed laminar flow. Both options (RVA or LVA ligation) cause a significant flow reduction near the aneurysm remnant with a retained flow rate. The impact of RVA ligation is, however, significantly higher. This in vitro case study shows that flow reduction near the aneurysm remnant can be achieved by Hunterian ligation and that this effect depends largely on the selection of the ligated vessel. Thus the ability of the proposed in vitro pipe-line to improve hemodynamic impact of the proposed therapy was successfully proved. Y1 - 2014 U6 - https://doi.org/10.5301/ijao.5000314 VL - 37 IS - 4 SP - 325 EP - 335 ER - TY - CHAP A1 - Stoppel, Sergej A1 - Hege, Hans-Christian A1 - Wiebel, Alexander T1 - Visibility-driven depth determination of surface patches in direct volume rendering T2 - EuroVis - Short Papers 2014 N2 - This paper presents an algorithm called surfseek for selecting surfaces on the most visible features in direct volume rendering (DVR). The algorithm is based on a previously published technique (WYSIWYP) for picking 3D locations in DVR. The new algorithm projects a surface patch on the DVR image, consisting of multiple rays. For each ray the algorithm uses WYSIWYP or a variant of it to find the candidates for the most visible locations along the ray. Using these candidates the algorithm constructs a graph and computes a minimum cut on this graph. The minimum cut represents a visible and typically rather smooth surface. In the last step the selected surface is displayed. We provide examples for results using artificially generated and real-world data sets. Y1 - 2014 U6 - https://doi.org/10.2312/eurovisshort.20141164 SP - 97 EP - 101 ER - TY - JOUR A1 - Lindow, Norbert A1 - Baum, Daniel A1 - Hege, Hans-Christian T1 - Ligand Excluded Surface: A New Type of Molecular Surface JF - IEEE Transactions on Visualization and Computer Graphics N2 - The most popular molecular surface in molecular visualization is the solvent excluded surface (SES). It provides information about the accessibility of a biomolecule for a solvent molecule that is geometrically approximated by a sphere. During a period of almost four decades, the SES has served for many purposes – including visualization, analysis of molecular interactions and the study of cavities in molecular structures. However, if one is interested in the surface that is accessible to a molecule whose shape differs significantly from a sphere, a different concept is necessary. To address this problem, we generalize the definition of the SES by replacing the probe sphere with the full geometry of the ligand defined by the arrangement of its van der Waals spheres. We call the new surface ligand excluded surface (LES) and present an efficient, grid-based algorithm for its computation. Furthermore, we show that this algorithm can also be used to compute molecular cavities that could host the ligand molecule. We provide a detailed description of its implementation on CPU and GPU. Furthermore, we present a performance and convergence analysis and compare the LES for several molecules, using as ligands either water or small organic molecules. Y1 - 2014 U6 - https://doi.org/10.1109/TVCG.2014.2346404 VL - 20 IS - 12 SP - 2486 EP - 2495 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Schaller, Jens A1 - Kertzscher, Ulrich A1 - Petz, Christoph A1 - Hege, Hans-Christian A1 - Spuler, Andreas T1 - Reproducibility of Image-Based Analysis of Cerebral Aneurysm Geometry and Hemodynamics: An In-Vitro Study of Magnetic Resonance Imaging, Computed Tomography, and Three-Dimensional Rotational Angiography JF - Journal of Neurological Surgery, Part A: Central European Neurosurgery Y1 - 2013 U6 - https://doi.org/10.1055/s-0033-1342937 VL - 74 IS - 5 SP - 294 EP - 302 ER - TY - JOUR A1 - Sips, Mike A1 - Kothur, Patrick A1 - Unger, Andrea A1 - Hege, Hans-Christian A1 - Dransch, Doris T1 - A Visual Analytics Approach to Multiscale Exploration of Environmental Time Series JF - IEEE Transactions on Visualization and Computer Graphics N2 - We present a Visual Analytics approach that addresses the detection of interesting patterns in numerical time series, specifically from environmental sciences. Crucial for the detection of interesting temporal patterns are the time scale and the starting points one is looking at. Our approach makes no assumption about time scale and starting position of temporal patterns and consists of three main steps: an algorithm to compute statistical values for all possible time scales and starting positions of intervals, visual identification of potentially interesting patterns in a matrix visualization, and interactive exploration of detected patterns. We demonstrate the utility of this approach in two scientific scenarios and explain how it allowed scientists to gain new insight into the dynamics of environmental systems. Y1 - 2012 U6 - https://doi.org/10.1109/TVCG.2012.191 VL - 18 IS - 12 SP - 2899 EP - 2907 ER - TY - JOUR A1 - Weinkauf, Tino A1 - Hege, Hans-Christian A1 - Theisel, Holger T1 - Advected Tangent Curves: A General Scheme for Characteristic Curves of Flow Fields JF - Computer Graphics Forum N2 - We present the first general scheme to describe all four types of characteristic curves of flow fields – stream, path, streak, and time lines – as tangent curves of a derived vector field. Thus, all these lines can be obtained by a simple integration of an autonomous ODE system. Our approach draws on the principal ideas of the recently introduced tangent curve description of streak lines. We provide the first description of time lines as tangent curves of a derived vector field, which could previously only be constructed in a geometric manner. Furthermore, our scheme gives rise to new types of curves. In particular, we introduce advected stream lines as a parameter-free variant of the time line metaphor. With our novel mathematical description of characteristic curves, a large number of feature extraction and analysis tools becomes available for all types of characteristic curves, which were previously only available for stream and path lines. We will highlight some of these possible applications including the computation of time line curvature fields and the extraction of cores of swirling advected stream lines. Y1 - 2012 U6 - https://doi.org/10.1111/j.1467-8659.2012.03063.x VL - 31 IS - 2pt4 SP - 825 EP - 834 ER - TY - CHAP A1 - Heller, Markus O. A1 - Wurl, Alexander A1 - Perka, Carsten A1 - Hege, Hans-Christian T1 - In vivo gluteus medius volume and shape variations across gender and disease status BT - Proceedings of ESB2012 - 18th Congress of the European Society of Biomechanics, Lisbon, Portugal, 1–4 July 2012 T2 - Journal of Biomechanics Y1 - 2012 U6 - https://doi.org/10.1016/S0021-9290(12)70359-7 VL - 45, Suppl. 1 SP - S358 ER - TY - GEN A1 - Hoerth, Rebecca M. A1 - Baum, Daniel A1 - Knötel, David A1 - Prohaska, Steffen A1 - Willie, Bettina M. A1 - Duda, Georg A1 - Hege, Hans-Christian A1 - Fratzl, Peter A1 - Wagermaier, Wolfgang T1 - Registering 2D and 3D Imaging Data of Bone during Healing N2 - Purpose/Aims of the Study: Bone’s hierarchical structure can be visualized using a variety of methods. Many techniques, such as light and electron microscopy generate two-dimensional (2D) images, while micro computed tomography (μCT) allows a direct representation of the three-dimensional (3D) structure. In addition, different methods provide complementary structural information, such as the arrangement of organic or inorganic compounds. The overall aim of the present study is to answer bone research questions by linking information of different 2D and 3D imaging techniques. A great challenge in combining different methods arises from the fact that they usually reflect different characteristics of the real structure. Materials and Methods: We investigated bone during healing by means of μCT and a couple of 2D methods. Backscattered electron images were used to qualitatively evaluate the tissue’s calcium content and served as a position map for other experimental data. Nanoindentation and X-ray scattering experiments were performed to visualize mechanical and structural properties. Results: We present an approach for the registration of 2D data in a 3D μCT reference frame, where scanning electron microscopies serve as a methodic link. Backscattered electron images are perfectly suited for registration into μCT reference frames, since both show structures based on the same physical principles. We introduce specific registration tools that have been developed to perform the registration process in a semi-automatic way. Conclusions: By applying this routine, we were able to exactly locate structural information (e.g. mineral particle properties) in the 3D bone volume. In bone healing studies this will help to better understand basic formation, remodeling and mineralization processes. T3 - ZIB-Report - 15-01 Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-53426 SN - 1438-0064 ER - TY - CHAP A1 - Hege, Hans-Christian T1 - Visual analysis of molecular dynamics data using geometric and topological methods T2 - Forum "Math for Industry" 2014 Y1 - 2014 VL - 57 SP - 45 EP - 46 PB - Institute of Mathematics for Industry, Kyushu University CY - Fukuoka, Japan ER - TY - JOUR A1 - Heinze, Rieke A1 - Dipankar, Anurag A1 - Henken, Cintia Carbajal A1 - Moseley, Christopher A1 - Sourdeval, Odran A1 - Trömel, Silke A1 - Xie, Xinxin A1 - Adamidis, Panos A1 - Ament, Felix A1 - Baars, Holger A1 - Barthlott, Christian A1 - Behrendt, Andreas A1 - Blahak, Ulrich A1 - Bley, Sebastian A1 - Brdar, Slavko A1 - Brueck, Matthias A1 - Crewell, Susanne A1 - Deneke, Hartwig A1 - Di Girolamo, Paolo A1 - Evaristo, Raquel A1 - Fischer, Jürgen A1 - Frank, Christopher A1 - Friederichs, Petra A1 - Göcke, Tobias A1 - Gorges, Ksenia A1 - Hande, Luke A1 - Hanke, Moritz A1 - Hansen, Akio A1 - Hege, Hans-Christian A1 - Hose, Corinna A1 - Jahns, Thomas A1 - Kalthoff, Norbert A1 - Klocke, Daniel A1 - Kneifel, Stefan A1 - Knippertz, Peter A1 - Kuhn, Alexander A1 - van Laar, Thriza A1 - Macke, Andreas A1 - Maurer, Vera A1 - Mayer, Bernhard A1 - Meyer, Catrin I. A1 - Muppa, Shravan K. A1 - Neggers, Roeland A. J. A1 - Orlandi, Emiliano A1 - Pantillon, Florian A1 - Pospichal, Bernhard A1 - Röber, Niklas A1 - Scheck, Leonhard A1 - Seifert, Axel A1 - Seifert, Patric A1 - Senf, Fabian A1 - Siligam, Pavan A1 - Simmer, Clemens A1 - Steinke, Sandra A1 - Stevens, Bjorn A1 - Wapler, Kathrin A1 - Weniger, Michael A1 - Wulfmeyer, Volker A1 - Zängl, Günther A1 - Zhang, Dan A1 - Quaas, Johannes T1 - Large-eddy simulations over Germany using ICON: a comprehensive evaluation JF - Quarterly Journal of the Royal Meteorological Society N2 - Large-eddy simulations (LES) with the new ICOsahedral Non-hydrostatic atmosphere model (ICON) covering Germany are evaluated for four days in spring 2013 using observational data from various sources. Reference simulations with the established Consortium for Small-scale Modelling (COSMO) numerical weather prediction model and further standard LES codes are performed and used as a reference. This comprehensive evaluation approach covers multiple parameters and scales, focusing on boundary-layer variables, clouds and precipitation. The evaluation points to the need to work on parametrizations influencing the surface energy balance, and possibly on ice cloud microphysics. The central purpose for the development and application of ICON in the LES configuration is the use of simulation results to improve the understanding of moist processes, as well as their parametrization in climate models. The evaluation thus aims at building confidence in the model's ability to simulate small- to mesoscale variability in turbulence, clouds and precipitation. The results are encouraging: the high-resolution model matches the observed variability much better at small- to mesoscales than the coarser resolved reference model. In its highest grid resolution, the simulated turbulence profiles are realistic and column water vapour matches the observed temporal variability at short time-scales. Despite being somewhat too large and too frequent, small cumulus clouds are well represented in comparison with satellite data, as is the shape of the cloud size spectrum. Variability of cloud water matches the satellite observations much better in ICON than in the reference model. In this sense, it is concluded that the model is fit for the purpose of using its output for parametrization development, despite the potential to improve further some important aspects of processes that are also parametrized in the high-resolution model. Y1 - 2017 U6 - https://doi.org/10.1002/qj.2947 VL - 143 IS - 702 SP - 69 EP - 100 ER - TY - JOUR A1 - Conrad, Tim A1 - Karsch, K. A1 - Obermeier, Patrick A1 - Seeber, L. A1 - Chen, X. A1 - Tief, Franziska A1 - Muehlhans, S. A1 - Hoppe, Christian A1 - Boettcher, Sindy A1 - Diedrich, S. A1 - Rath, Barbara T1 - Human Parechovirus Infections Associated with Seizures and Rash: A Syndromic Surveillance Study in Children JF - The Pediatric Infectious Disease Journal Y1 - 2015 VL - 34 IS - 10 ER - TY - JOUR A1 - Conrad, Tim A1 - Rath, Barbara A1 - Tief, Franziska A1 - Karsch, K. A1 - Muehlhans, S. A1 - Obermeier, Patrick A1 - Adamou, E. A1 - Chen, X. A1 - Seeber, L. A1 - Peiser, Ch. A1 - Hoppe, Christian A1 - von Kleist, Max A1 - Schweiger, Brunhilde T1 - Towards a personalized approach to managing of influenza infections in infants and children - food for thought and a note on oseltamivir JF - Infectious Disorders - Drug Targets Y1 - 2013 VL - 13 IS - 1 SP - 25 EP - 33 ER - TY - JOUR A1 - Kozlíková, Barbora A1 - Krone, Michael A1 - Falk, Martin A1 - Lindow, Norbert A1 - Baaden, Marc A1 - Baum, Daniel A1 - Viola, Ivan A1 - Parulek, Julius A1 - Hege, Hans-Christian T1 - Visualization of Biomolecular Structures: State of the Art Revisited JF - Computer Graphics Forum N2 - Structural properties of molecules are of primary concern in many fields. This report provides a comprehensive overview on techniques that have been developed in the fields of molecular graphics and visualization with a focus on applications in structural biology. The field heavily relies on computerized geometric and visual representations of three-dimensional, complex, large and time-varying molecular structures. The report presents a taxonomy that demonstrates which areas of molecular visualization have already been extensively investigated and where the field is currently heading. It discusses visualizations for molecular structures, strategies for efficient display regarding image quality and frame rate, covers different aspects of level of detail and reviews visualizations illustrating the dynamic aspects of molecular simulation data. The survey concludes with an outlook on promising and important research topics to foster further success in the development of tools that help to reveal molecular secrets. Y1 - 2016 U6 - https://doi.org/10.1111/cgf.13072 VL - 36 IS - 8 SP - 178 EP - 204 ER - TY - GEN A1 - Günther, Tobias A1 - Kuhn, Alexander A1 - Hege, Hans-Christian A1 - Gross, Markus A1 - Theisel, Holger T1 - Progressive Monte-Carlo Rendering of Atmospheric Flow Features Across Scales T2 - 69th Annual Meeting of the APS Division of Fluid Dynamics, Gallery of Fluid Motion, Nov 20-22, 2016, Portland, OR, USA. N2 - To improve existing weather prediction and reanalysis capabilities, high-resolution and multi-modal climate data becomes an increasingly important topic. The advent of increasingly dense numerical simulation of atmospheric phenomena, provides new means to better understand dynamic processes and to visualize structural flow patterns that remain hidden otherwise. In the presented illustrations we demonstrate an advanced technique to visualize multiple scales of dense flow fields and Lagrangian patterns therein, simulated by state-of-the-art simulation models for each scale. They provide a deeper insight into the structural differences and patterns that occur on each scale and highlight the complexity of flow phenomena in our atmosphere. Y1 - 2016 U6 - https://doi.org/10.1103/APS.DFD.2016.GFM.P0030 ER - TY - CHAP A1 - Kuhn, Alexander A1 - Engelke, Wito A1 - Flatken, Markus A1 - Hege, Hans-Christian A1 - Hotz, Ingrid T1 - Topology-based Analysis for Multimodal Atmospheric Data of Volcano Eruptions T2 - Topological Methods in Data Analysis and Visualization IV Y1 - 2017 U6 - https://doi.org/10.1007/978-3-319-44684-4_2 SP - 35 EP - 50 PB - Springer CY - Cham, Schweiz ER - TY - GEN A1 - Stoppel, Sergej A1 - Hege, Hans-Christian A1 - Wiebel, Alexander T1 - Visibility-Driven Depth Determination of Surface Patches in Direct Volume Rendering N2 - This paper presents an algorithm called surfseek for selecting surfaces on the most visible features in direct volume rendering (DVR). The algorithm is based on a previously published technique (WYSIWYP) for picking 3D locations in DVR. The new algorithm projects a surface patch on the DVR image, consisting of multiple rays. For each ray the algorithm uses WYSIWYP or a variant of it to find the candidates for the most visible locations along the ray. Using these candidates the algorithm constructs a graph and computes a minimum cut on this graph. The minimum cut represents a very visible but relatively smooth surface. In the last step the selected surface is displayed. We provide examples for the results in real-world dataset as well as in artificially generated datasets. T3 - ZIB-Report - 14-11 KW - Interaction Techniques KW - Volume Rendering KW - Picking KW - Surfaces Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-50266 SN - 1438-0064 ER - TY - GEN A1 - Polthier, Konrad A1 - Sullivan, John A1 - Ziegler, Günter M. A1 - Hege, Hans-Christian ED - Deuflhard, Peter ED - et al., T1 - Visualization T2 - MATHEON - Mathematics for Key Technologies Y1 - 2014 SN - 978-3-03719-137-8 U6 - https://doi.org/10.4171/137 SP - 335 EP - 339 PB - European Mathematical Society ER - TY - GEN A1 - Titschack, Jürgen A1 - Baum, Daniel T1 - Advanced computed tomography analyses of cold-water coral mound cores: new insights into mound formation processes T2 - Poster, 19th International Sedimentological Congress, Geneva, Switzerland, 2014, August 18 - 22 Y1 - 2014 ER - TY - GEN A1 - Titschack, Jürgen A1 - Baum, Daniel T1 - Ambient occlusion - a powerful algorithm to segment skeletal intrapores and gastral cavities in dendrophyllid cold-water corals T2 - Poster, 31st IAS Meeting of Sedimentology, 2015, June 22-25, Kraków, Poland Y1 - 2015 ER - TY - JOUR A1 - Kasten, Jens A1 - Reininghaus, Jan A1 - Hotz, Ingrid A1 - Hege, Hans-Christian A1 - Noack, Bernd A1 - Daviller, Guillaume A1 - Morzyński, Marek T1 - Acceleration feature points of unsteady shear flows JF - Archives of Mechanics N2 - A framework is proposed for extracting features in 2D transient flows, based on the acceleration field to ensure Galilean invariance. The minima of the acceleration magnitude, i.e. a superset of the acceleration zeros, are extracted and discriminated into vortices and saddle points --- based on the spectral properties of the velocity Jacobian. The extraction of topological features is performed with purely combinatorial algorithms from discrete computational topology. The feature points are prioritized with persistence, as a physically meaningful importance measure. These features are tracked in time with a robust algorithm for tracking features. Thus a space-time hierarchy of the minima is built and vortex merging events are detected. The acceleration feature extraction strategy is applied to three two-dimensional shear flows: (1) an incompressible periodic cylinder wake, (2) an incompressible planar mixing layer and (3) a weakly compressible planar jet. The vortex-like acceleration feature points are shown to be well aligned with acceleration zeros, maxima of the vorticity magnitude, minima of pressure field and minima of λ2. Y1 - 2016 VL - 68 IS - 1 SP - 55 EP - 80 ER - TY - GEN A1 - Kasten, Jens A1 - Reininghaus, Jan A1 - Hotz, Ingrid A1 - Hege, Hans-Christian A1 - Noack, Bernd A1 - Daviller, Guillaume A1 - Morzyński, Marek T1 - Acceleration feature points of unsteady shear flows N2 - A framework is proposed for extracting features in 2D transient flows, based on the acceleration field to ensure Galilean invariance. The minima of the acceleration magnitude, i.e. a superset of the acceleration zeros, are extracted and discriminated into vortices and saddle points --- based on the spectral properties of the velocity Jacobian. The extraction of topological features is performed with purely combinatorial algorithms from discrete computational topology. The feature points are prioritized with persistence, as a physically meaningful importance measure. These features are tracked in time with a robust algorithm for tracking features. Thus a space-time hierarchy of the minima is built and vortex merging events are detected. The acceleration feature extraction strategy is applied to three two-dimensional shear flows: (1) an incompressible periodic cylinder wake, (2) an incompressible planar mixing layer and (3) a weakly compressible planar jet. The vortex-like acceleration feature points are shown to be well aligned with acceleration zeros, maxima of the vorticity magnitude, minima of pressure field and minima of λ2. T3 - ZIB-Report - 15-65 Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-58397 SN - 1438-0064 ER - TY - THES A1 - Schotte, Merlind T1 - Automatische Dickenbestimmung der mineralisierten Schicht in Skelettelementen von Knorpelfischen anhand von CT- Bilddaten N2 - Diese Bachelorarbeit beschäftigt sich mit der Entwicklung eines allgemeinen Verfahrens, welches die Dicke der mineralisierten Schicht von Haikieferelementen automatisch bestimmt. Dabei soll das Verfahren die Dicke näherungsweise im zweidimensionalen (2D) Raum sowie im dreidimensionalen (3D) Raum anhand von Computertomografie-Scans berechnen (im Folgenden als zweidimensionaler bzw. dreidimensionaler Fall bezeichnet). Es werden drei mögliche Verfahren eingeführt und im Anschluss auf ihre Verwendbarkeit analysiert. Für die Implementierung zur Dickenbestimmung wird der Kern der Rayburst Sampling Methode verwendet und im Weiteren für den 2D-Raum durch kleinere Optimierungen verbessert. Die Überprüfung der Genauigkeit des für den zweidimensionalen Fall entwickelten Programms erfolgt manuell. Für einen Vergleich im 3D-Raum wird ein zweites Verfahren programmiert, das auf der Berechnung der Isoflächen basiert. Diese Arbeit ist in den Bereich der angewandten Mathematik mit dem Schwerpunkt Informatik einzuordnen. Das entwickelte Programm wird im Anschluss Anwendung im Bereich der Biologie am Max-Planck-Institut für Grenzflächen- und Kolloidforschung Potsdam-Golm finden. Y1 - 2015 ER - TY - CHAP A1 - Jácome, Leonardo Agudo A1 - Eggeler, Gunter A1 - Pöthkow, Kai A1 - Paetsch, Olaf A1 - Hege, Hans-Christian T1 - Three-Dimensional Characterization of Superdislocation Interactions in the High Temperature and Low Stress Creep Regime of Ni-Base Superalloy Single Crystals T2 - Proceedings of CREEP 2015 – 13th International Conference on Creep and Fracture of Engineering Materials and Structures, May 31 – June 4, 2015, Toulouse, France N2 - Monocrystaline Ni-base superalloys are the material of choice for first row blades in jet engine gas turbines. Using a novel visualization tool for 3D reconstruction and visualization of dislocation line segments from stereo-pairs of scanning transmission electron microscopies, the superdislocation substructures in Ni-base superalloy LEK 94 (crept to ε = 26%) are characterized. Probable scenarios are discussed, how these dislocation substructures form. Y1 - 2015 SP - 16 EP - 17 ER - TY - GEN A1 - Bojarovski, Stefan A1 - Hege, Hans-Christian A1 - Lie, Han Cheng A1 - Weber, Marcus T1 - Topological analysis and visualization of scalar functions characterizing conformational transitions of molecules on multiple time-scales T2 - Shape Up 2015 - Exercises in Materials Geometry and Topology, 14-18 Sept. 2015, Berlin, Germany N2 - Molecular processes such as protein folding or ligand-receptor-binding can be understood by analyzing the free energy landscape. Those processes are often metastable, i.e. the molecular systems remain in basins around local minima of the free energy landscape, and in rare cases undergo gauche transitions between metastable states by passing saddle-points of this landscape. By discretizing the configuration space, this can be modeled as a discrete Markov process. One way to compute the transition rates between conformations of a molecular system is by utilizing Transition Path Theory and the concept of committor functions. A fundamental problem from the computational point of view is that many time-scales are involved, ranging from 10^(-14) sec for the fastest motion to 10^(-6) sec or more for conformation changes that cause biological effects. The goal of our work is to provide a better understanding of such transitions in configuration space on various time-scales by analyzing characteristic scalar functions topologically and geometrically. We are developing suitable visualization and interaction techniques to support our analysis. For example, we are analyzing a transition rate indicator function by computing and visualizing its Reeb graph together with the sets of molecular states corresponding to maxima of the transition rate indicator function. A particular challenge is the high dimensionality of the domain which does not allow for a straightforward visualization of the function. The computational topology approach to the analysis of the transition rate indicator functions for a molecular system allows to explore different time scales of the system by utilizing coarser or finer topological partitioning of the function. A specific goal is the development of tools for analyzing the hierarchy of these partitionings. This approach tackles the analysis of a complex and sparse dataset from a different angle than the well-known spectral analysis of Markov State Models. Y1 - 2015 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Osman, Jan A1 - Mevert, Ricardo A1 - Kertzscher, Ulrich A1 - Pöthkow, Kai A1 - Hege, Hans-Christian T1 - Turbulence in blood damage modeling JF - The International Journal of Artificial Organs N2 - Purpose: To account for the impact of turbulence in blood damage modeling, a novel approach based on the generation of instantaneous flow fields from RANS simulations is proposed. Methods: Turbulent flow in a bileaflet mechanical heart valve was simulated using RANS-based (SST k-ω) flow solver using FLUENT 14.5. The calculated Reynolds shear stress (RSS) field is transformed into a set of divergence-free random vector fields representing turbulent velocity fluctuations using procedural noise functions. To consider the random path of the blood cells, instantaneous flow fields were computed for each time step by summation of RSS-based divergence-free random and mean velocity fields. Using those instantaneous flow fields, instantaneous pathlines and corresponding point-wise instantaneous shear stresses were calculated. For a comparison, averaged pathlines based on mean velocity field and respective viscous shear stresses together with RSS values were calculated. Finally, the blood damage index (hemolysis) was integrated along the averaged and instantaneous pathlines using a power law approach and then compared. Results: Using RSS in blood damage modeling without a correction factor overestimates damaging stress and thus the blood damage (hemolysis). Blood damage histograms based on both presented approaches differ. Conclusions: A novel approach to calculate blood damage without using RSS as a damaging parameter is established. The results of our numerical experiment support the hypothesis that the use of RSS as a damaging parameter should be avoided. Y1 - 2016 U6 - https://doi.org/10.5301/ijao.5000476 VL - 39 IS - 4 SP - 147 EP - 210 ER - TY - JOUR A1 - Willie, Bettina M. A1 - Pap, Thomas A1 - Perka, Carsten A1 - Schmidt, Carsten Oliver A1 - Eckstein, Felix A1 - Arampatzis, Adamantios A1 - Hege, Hans-Christian A1 - Madry, Henning A1 - Vortkamp, Andrea A1 - Duda, Georg T1 - OVERLOAD – Rolle der Gelenküberlastung in der primären Arthrose – Die Krankheitsprogression verstehen und vermeiden JF - Zeitschrift für Rheumatologie N2 - Intakte Gelenke sind eine Voraussetzung für das Funktionieren des Skeletts und die Mobilität im Lebensalltag. Ein gesunder Bewegungsapparat ist die Grundlage für die Funktionsfähigkeit des Herz-Kreislauf-Systems wie auch der Immunabwehr. Bewegungs- und Physiotherapie sowie verschiedene Formen der Patientenaktivität stellen essenzielle klinische Ansätze in der Behandlung von neurodegenerativen Erkrankungen, Schlaganfall, Diabetes und Krebs dar. Kommt es zu degenerativen Veränderungen von Gelenken, bedeutet dies eine wesentliche Beeinträchtigung der Mobilität. Nächtliche Schmerzen und Schlafstörungen treten in fortgeschrittenen Stadien auf und sind besonders belastend. Arthrose wird auch als degenerative Gelenkerkrankung bezeichnet. Sie geht mit Veränderungen in der Struktur und Zusammensetzung des Gelenkknorpels wie auch des verkalkten Knorpels, der subchondralen Kortikalis, der subchondralen Spongiosa, des Meniskus, der Gelenkkapsel und der Synovialis einher, was schließlich zur Degeneration dieser Gewebe führt, aus denen sich die Synovialgelenke zusammensetzen. Y1 - 2015 U6 - https://doi.org/10.1007/s00393-014-1561-2 VL - 74 SP - 618 EP - 621 ER -