TY - GEN A1 - Hege, Hans-Christian A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Zöckler, Malte T1 - A Generalized Marching Cubes Algorithm Based on Non-Binary Classifications N2 - We present a new technique for generating surface meshes from a uniform set of discrete samples. Our method extends the well-known marching cubes algorithm used for computing polygonal isosurfaces. While in marching cubes each vertex of a cubic grid cell is binary classified as lying above or below an isosurface, in our approach an arbitrary number of vertex classes can be specified. Consequently the resulting surfaces consist of patches separating volumes of two different classes each. Similar to the marching cubes algorithm all grid cells are traversed and classified according to the number of different vertex classes involved and their arrangement. The solution for each configuration is computed based on a model that assigns probabilities to the vertices and interpolates them. We introduce an automatic method to find a triangulation which approximates the boundary surfaces - implicitly given by our model - in a topological correct way. Look-up tables guarantee a high performance of the algorithm. In medical applications our method can be used to extract surfaces from a 3D segmentation of tomographic images into multiple tissue types. The resulting surfaces are well suited for subsequent volumetric mesh generation, which is needed for simulation as well as visualization tasks. The proposed algorithm provides a robust and unique solution, avoiding ambiguities occuring in other methods. The method is of great significance in modeling and animation too, where it can be used for polygonalization of non-manifold implicit surfaces. T3 - ZIB-Report - SC-97-05 Y1 - 1997 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-2741 ER - TY - GEN A1 - Beck, Rudolf A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebass, Martin A1 - Stalling, Detlev T1 - Numerical Algorithms and Visualization in Medical Treament Planning N2 - After a short summary on therapy planning and the underlying technologies we discuss quantitative medicine by giving a short overview on medical image data, summarizing some applications of computer based treatment planning, and outlining requirements on medical planning systems. Then we continue with a description of our medical planning system {\sf HyperPlan}. It supports typical working steps in therapy planning, like data aquisition, segmentation, grid generation, numerical simulation and optimization, accompanying these with powerful visualization and interaction techniques. T3 - ZIB-Report - SC-96-54 Y1 - 1996 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-2643 ER - TY - GEN A1 - Deuflhard, Peter A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Beck, Rudolf A1 - Hege, Hans-Christian T1 - Hyperthermia Treatment Planning in Clinical Cancer Therapy: Modelling, Simulation and Visualization N2 - \noindent The speaker and his co-workers in Scientific Computing and Visualization have established a close cooperation with medical doctors at the Rudolf--Virchow--Klinikum of the Humboldt University in Berlin on the topic of regional hyperthermia. In order to permit a patient--specific treatment planning, a special software system ({\sf\small HyperPlan}) has been developed. \noindent A mathematical model of the clinical system ({\it radio frequency applicator with 8 antennas, water bolus, individual patient body}) involves Maxwell's equations in inhomogeneous media and a so--called bio--heat transfer PDE describing the temperature distribution in the human body. The electromagnetic field and the thermal phenomena need to be computed at a speed suitable for the clinical environment. An individual geometric patient model is generated as a quite complicated tetrahedral ``coarse'' grid (several thousands of nodes). Both Maxwell's equations and the bio--heat transfer equation are solved on that 3D--grid by means of {\em adaptive} multilevel finite element methods, which automatically refine the grid where necessary in view of the required accuracy. Finally optimal antenna parameters for the applicator are determined . \noindent All steps of the planning process are supported by powerful visualization methods. Medical images, contours, grids, simulated electromagnetic fields and temperature distributions can be displayed in combination. A number of new algorithms and techniques had to be developed and implemented. Special emphasis has been put on advanced 3D interaction methods and user interface issues. T3 - ZIB-Report - SC-97-26 Y1 - 1997 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-2958 ER - TY - CHAP A1 - Beck, Rudolf A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebass, Martin A1 - Stalling, Detlev ED - Hege, Hans-Christian ED - Polthier, Konrad T1 - Numerical Algorithms and Visualization in Medical Treament Planning T2 - Visualization and Mathematics Y1 - 1997 SP - 303 EP - 328 PB - Springer-Verlag ER - TY - CHAP A1 - Nadobny, Johanna A1 - Wust, Peter A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Felix, Roland T1 - A Quantitative Comparison between the VSIE and the FDTD method using Electrically Equivalent Patient and Antenna Models T2 - Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997 Y1 - 1997 SP - 145 ER - TY - JOUR A1 - Gellermann, Johanna A1 - Wust, Peter A1 - Stalling, Detlev A1 - Seebass, Martin A1 - Nadobny, Johanna A1 - Beck, Rudolf A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Felix, Roland T1 - Clinical evaluation and verification of the hyperthermia treatment planning system hyperplan JF - Int J Radiat Oncol Biol Phys Y1 - 2000 VL - 47 IS - 4 SP - 1145 EP - 1156 ER - TY - CHAP A1 - Deuflhard, Peter A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Beck, Rudolf A1 - Hege, Hans-Christian ED - Sydow, Achim T1 - Hyperthermia Treatment Planning in Clinical Cancer Therapy:Modelling, Simulation, and Visualization T2 - Computational Physics, Chemistry and Biology Y1 - 1997 VL - 3 PB - Wissenschaft und Technik Verlag CY - Plenary keynote talk, 15th IMACS World Congress 1997 on Scientific Computation, Modelling and Applied Mathematics ER - TY - CHAP A1 - Gellermann, Johanna A1 - Wust, Peter A1 - Stalling, Detlev A1 - Tilly, Wolfgang A1 - Nadobny, Johanna A1 - Seebass, Martin A1 - Deuflhard, Peter A1 - Felix, Roland A1 - Budach, Volker T1 - First Clinical Experiences with the Hyperthermia Planning System HyperPlan T2 - Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997 Y1 - 1997 SP - 79 ER - TY - JOUR A1 - Gellermann, Johanna A1 - Wust, Peter A1 - Stalling, Detlev A1 - Seebaß, Martin A1 - Nadobny, Jacek A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Felix, Roland T1 - Clinical evaluation and verification of the hyperthermia treatment planning system HyperPlan JF - Int. J. Radiat. Oncol. Biol. Phys. Y1 - 2000 U6 - https://doi.org/10.1016/S0360-3016(00)00425-9 VL - 47(4) SP - 1145 EP - 1156 ER - TY - CHAP A1 - Beck, Rudolf A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebaß, Martin A1 - Stalling, Detlev ED - Hege, Hans-Christian ED - Polthier, Konrad T1 - Numerical Algorithms and Visualization in Medical Treatment Planning T2 - Visualization and Mathematics 1997 Y1 - 1996 SP - 303 EP - 328 PB - Springer, Heidelberg ER - TY - JOUR A1 - Wust, Peter A1 - Nadobny, Jacek A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Gellermann, Johanna A1 - Hege, Hans-Christian A1 - Deuflhard, Peter T1 - Influence of Patient Models and Numerical Methods on Predicted Power Deposition Patterns JF - Int. Journal Hyperthermia Y1 - 1999 VL - 15 IS - 6 SP - 519 EP - 540 ER - TY - CHAP A1 - Stalling, Detlev A1 - Seebaß, Martin A1 - Zachow, Stefan T1 - Mehrschichtige Oberflächenmodelle zur computergestützten Planung in der Chirurgie T2 - Bildverarbeitung für die Medizin 1999 - Algorithmen, Anwendungen Y1 - 1999 SP - 203 EP - 207 PB - Springer-Verlag, Berlin ER - TY - CHAP A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Hege, Hans-Christian A1 - Wust, Peter A1 - Felix, Roland A1 - Deuflhard, Peter T1 - New Features of HyperPlan, a Hyperthermia Planning System T2 - Proc. Hyperthermia in Clincal Oncology Y1 - 1998 SP - 16 CY - Venice ER - TY - CHAP A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Zöckler, Malte A1 - Hege, Hans-Christian A1 - Wust, Peter A1 - Felix, Roland A1 - Deuflhard, Peter T1 - Surface Mesh Generation for Numerical Simulations of Hyperthermia Treatments T2 - Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology (ESHO-97) Y1 - 1997 SP - 146 ER - TY - CHAP A1 - Deuflhard, Peter A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Beck, Rudolf A1 - Hege, Hans-Christian ED - Sydow, Achim T1 - Hyperthermia Treatment Planning in Clinical Therapy T2 - Computational Physics, Chemistry and Biology (Proceedings of the 15th IMACS World Congress 1997 on Scientific Computation 3, Modelling and Applied Mathematics) Y1 - 1997 SP - 9 EP - 17 PB - Wissenschaft und Technik Verlag ER - TY - CHAP A1 - Wust, Peter A1 - Nadobny, Jacek A1 - Gellermann, Johanna A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Felix, Roland T1 - Patient Models and Algorithms for Hyperthermia Planning T2 - Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology ESHO-97 Y1 - 1997 ER - TY - CHAP A1 - Nadobny, Jacek A1 - Wust, Peter A1 - Fähling, Horst A1 - Stalling, Detlev A1 - Seebaß, Martin A1 - Deuflhard, Peter A1 - Felix, Roland T1 - Numerical and Experimental Evaluation of E-Field and Absorbed Power in the Pelvic Region Using a Bone-Equivalent Phantom T2 - Proc. PIERS Progress in Electromagnetic Research Symposium Y1 - 1998 SP - 264 CY - Nantes ER - TY - JOUR A1 - Seebaß, Martin A1 - Wust, Peter A1 - Gellermann, Johanna A1 - Stalling, Detlev A1 - Nadobny, Jacek A1 - Felix, Roland T1 - Dreidimensionale Simulation der nicht-invasiven Radiowellen-Hyperthermie JF - Minimal Invasive Medizin Y1 - 1995 VL - 6 IS - 1 SP - 29 EP - 35 ER - TY - CHAP A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Nadobny, Jacek A1 - Wust, Peter A1 - Felix, Roland A1 - Deuflhard, Peter T1 - Three-Dimensional Finite Elements Mesh Generation for Numerical Simulations of Hyperthermia Treatments T2 - Proceedings of the 17th Congress on Hyperthermic Oncology Y1 - 1996 VL - 2 SP - 547 EP - 548 CY - Rome, Italy ER - TY - CHAP A1 - Stalling, Detlev A1 - Seebaß, Martin A1 - Hege, Hans-Christian A1 - Wust, Peter A1 - Deuflhard, Peter A1 - Felix, Roland T1 - HyperPlan - an Integrated System for Treatment Planning in Regional Hyperthermia T2 - Proceedings of the 17th Congress on Hyperthermic Oncology Y1 - 1996 VL - 2 SP - 552 EP - 554 CY - Rome, Italy ER - TY - JOUR A1 - Wust, Peter A1 - Nadobny, Johanna A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Gellermann, Johanna A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Felix, Roland T1 - Influence of patient models and numerical methods on predicted power deposition patterns JF - Int. J. Hyperthermia Y1 - 1999 VL - 15 IS - 6 SP - 519 EP - 540 ER - TY - CHAP A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Nadobny, Johanna A1 - Wust, Peter A1 - Felix, Roland A1 - Deuflhard, Peter ED - Franconi, Cafiero T1 - Three-Dimensional Finite Element Mesh Generation for Numerical Simulations of Hyperthermia Treatments T2 - Proc. of the 7th Int. Congress on Hyperthermic Oncology, Rome, Italy, April 1996 Y1 - 1996 VL - 2 SP - 547 EP - 548 ER - TY - CHAP A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Zöckler, M. A1 - Hege, Hans-Christian A1 - Wust, Peter A1 - Felix, Roland A1 - Deuflhard, Peter T1 - Surface Mesh Generation for Numerical Simulations of Hyperthermia Treatments T2 - Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997 Y1 - 1997 SP - 146 ER - TY - CHAP A1 - Wust, Peter A1 - Nadobny, Johanna A1 - Gellermann, Johanna A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Budach, Volker A1 - Felix, Roland T1 - Patient Models and Algorithms for Hyperthermia Planning T2 - Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997 Y1 - 1997 SP - 75 ER - TY - CHAP A1 - Stalling, Detlev A1 - Seebass, Martin A1 - Hege, Hans-Christian A1 - Wust, Peter A1 - Deuflhard, Peter A1 - Felix, Roland ED - Franconi, Cafiero T1 - HyperPlan - an integrated system for treatment planning in regional hyperthermia T2 - Proc. of the 7th Int. Congress on Hyperthermic Oncology, Rome, Italy, April 1996 Y1 - 1996 VL - 2 SP - 552 EP - 554 ER - TY - GEN A1 - Stalling, Detlev A1 - Seebass, Martin A1 - Zachow, Stefan T1 - Mehrschichtige Oberflächenmodelle zur computergestützten Planung in der Chirurgie N2 - Polygonale Schädelmodelle bilden ein wichtiges Hilfsmittel für computergestützte Planungen im Bereich der plastischen Chirurgie. Wir beschreiben, wie derartige Modelle automatisch aus hochaufgelösten CT-Datensätzen erzeugt werden können. Durch einen lokal steuerbaren Simplifizierungsalgorithmus werden die Modelle so weit vereinfacht, daß auch auf kleineren Graphikcomputern interaktives Arbeiten möglich wird. Die Verwendung eines speziellen Transparenzmodells ermöglicht den ungehinderten Blick auf die bei der Planung relevanten Knochenstrukturen und läßt den Benutzer zugleich die Kopfumrisse des Patienten erkennen. T3 - ZIB-Report - TR-98-05 KW - Isoflächen KW - Simplifizierung KW - Transparenzen Y1 - 1998 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-5661 ER - TY - GEN A1 - Stalling, Detlev A1 - Seebass, Martin A1 - Zöckler, Malte A1 - Hege, Hans-Christian T1 - Hyperthermia Treatment Planning with HyperPlan - User's Manual N2 - HyperPlan is a software system for performing 3D-simulations and treatment planning in regional hyperthermia. It allows the user to understand the complex effects of electromagnetic wave propagation and heat transport inside a patient's body. Optimized power amplitudes and phase settings can be calculated for the BSD radiowave applicators Sigma 60 and Sigma 2000 (eye-applicator). HyperPlan is built on top of the modular, object-oriented visualization system Amira. This system already contains powerful algorithms for image processing, geometric modelling and 3D graphics display. HyperPlan provides a number of hyperthermia-specific modules, allowing the user to create 3D tetrahedral patient models suitable for treatment planning. In addition, all numerical simulation modules required for hyperthermia simulation are part of HyperPlan. This guide provides a step-by-step introduction to hyperthermia planning using HyperPlan. It also describes the usage of the underlying visualization system Amira. T3 - ZIB-Report - 00-27 KW - image segmentation KW - grid generation KW - visualization KW - therapy planning Y1 - 2000 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-5957 ER -