TY - CHAP A1 - Petz, Christoph A1 - Stalling, Detlev A1 - Goubergrits, Leonid A1 - Affeld, Klaus A1 - Spuler, Andreas ED - Tolxdorff, Thomas T1 - Validierung von Strömungssimulationen in kardiovaskulären Anwendungen T2 - Bildverabeitung für die Medizin 2004 Y1 - 2004 SP - 356 EP - 360 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Thamsen, Bente A1 - Berthe, André A1 - Poethke, Jens A1 - Kertzscher, Ulrich A1 - Affeld, Klaus A1 - Petz, Christoph A1 - Hege, Hans-Christian A1 - Hoch, Heinrich A1 - Spuler, Andreas T1 - In Vitro Study of Near-Wall Flow in a Cerebral Aneurysm Model with and without Coils JF - American Journal of Neuroradiology Y1 - 2010 U6 - https://doi.org/10.3174/ajnr.A2121 VL - 31:8 SP - 1521 EP - 1528 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Wellnhofer, Ernst A1 - Kertzscher, Ulrich A1 - Affeld, Klaus A1 - Petz, Christoph A1 - Hege, Hans-Christian T1 - Coronary Artery WSS Profiling Using a Geometry Reconstruction Based on Biplane Angiography JF - Annals of Biomedical Engineering Y1 - 2009 U6 - https://doi.org/s10439-009-9656-7 VL - 37 IS - 4 SP - 682 EP - 691 PB - Springer ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Kertzscher, Ulrich A1 - Affeld, Klaus A1 - Petz, Christoph A1 - Stalling, Detlev T1 - Numerical Dye Washout Method as a Tool for Characterizing the Heart Valve Flow JF - ASAIO Journal Y1 - 2008 U6 - https://doi.org/10.1097/MAT.0b013e31815c5e38 VL - 54(1) SP - 50 EP - 57 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Timmel, Tobias A1 - Affeld, Klaus A1 - Petz, Christoph A1 - Stalling, Detlev A1 - Hege, Hans-Christian T1 - Characterization of an artificial valve flow using the numerical dye washout visualization technique JF - Artificial Organs Y1 - 2006 VL - 30(8) SP - 642 EP - 650 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Spuler, Andreas A1 - Schaller, Jens A1 - Wiegmann, Nils A1 - Berthe, Andre A1 - Hege, Hans-Christian A1 - Affeld, Klaus A1 - Kertzscher, Ulrich T1 - In vitro study of hemodynamic treatment improvement: Hunterian ligation of a fenestrated basilar artery aneurysm after coiling JF - The International Journal of Artificial Organs N2 - Hunterian ligation affecting hemodynamics in vessels was proposed to avoid rebleeding in a case of a fenestrated basilar artery aneurysm after incomplete coil occlusion. We studied the hemodynamics in vitro to predict the hemodynamic changes near the aneurysm remnant caused by Hunterian ligation. A transparent model was fabricated based on three-dimensional rotational angiography imaging. Arteries were segmented and reconstructed. Pulsatile flow in the artery segments near the partially occluded (coiled) aneurysm was investigated by means of particle image velocimetry. The hemodynamic situation was investigated before and after Hunterian ligation of either the left or the right vertebral artery (LVA/RVA). Since post-ligation flow rate in the basilar artery was unknown, reduced and retained flow rates were simulated for both ligation options. Flow in the RVA and in the corresponding fenestra vessel is characterized by a vortex at the vertebrobasilar junction, whereas the LVA exhibits undisturbed laminar flow. Both options (RVA or LVA ligation) cause a significant flow reduction near the aneurysm remnant with a retained flow rate. The impact of RVA ligation is, however, significantly higher. This in vitro case study shows that flow reduction near the aneurysm remnant can be achieved by Hunterian ligation and that this effect depends largely on the selection of the ligated vessel. Thus the ability of the proposed in vitro pipe-line to improve hemodynamic impact of the proposed therapy was successfully proved. Y1 - 2014 U6 - https://doi.org/10.5301/ijao.5000314 VL - 37 IS - 4 SP - 325 EP - 335 ER -