TY - BOOK A1 - Ternes, Thomas A1 - Bauer, Karl-Heinz A1 - Brauer, Frank A1 - Drewes, Jörg A1 - Joss, Adriano A1 - Hiller, Georg A1 - Jewell, Kevin A1 - Oehlmann, Jörg A1 - Radke, Michael A1 - Schulte-Oehlmann, Ulrike A1 - Schwartz, Thomas A1 - Seel, Peter A1 - Völker, Jeanette A1 - Weber, Lilo A1 - Weber, Marcus ED - Wilhelm, Christian T1 - Handlungsempfehlung zur integrativen Bewertung der weitergehenden Abwasserbehandlung von kommunalen Kläranlagen N2 - Das vorliegende Statuspapier beschreibt ein Konzept zur weitergehenden Abwasserbehandlung für die Bewertung von Aufbereitungsverfahren, sowohl in einer Pilotphase zur Auswahl von Verfah- rensoptionen als auch für die Bewertung großtechnischer Anlagen. Y1 - 2023 SN - 978-3-96862-563-8 VL - T1/2023 PB - DWA / GDCh ER - TY - JOUR A1 - Asadova, Nigar A1 - Achouri, Karim A1 - Arjas, Kristian A1 - Ajuguié, Baptiste A1 - Aydin, Roland A1 - Baron, Alexandre A1 - Beutel, Dominik A1 - Bodermann, Bernd A1 - Boussaoud, Kaoutar A1 - Burger, Sven A1 - Choi, Minseok A1 - Czajkowski, Krzysztof A1 - Evlyukhin, Andrey B. A1 - Fazel-Najafabadi, Atefeh A1 - Fernandez-Corbaton, Ivan A1 - Garg, Puneet A1 - Globosits, David A1 - Hohenester, Ulrich A1 - Kim, Hongyoon A1 - Kim, Seokwoo A1 - Lalanne, Philippe A1 - Le Ru, Eric C. A1 - Meyer, Jörg A1 - Mun, Jungho A1 - Patelli, Lorenzo A1 - Pflug, Lukas A1 - Rockstuhl, Carsten A1 - Rho, Junsuk A1 - Rotter, Stefan A1 - Stout, Brian A1 - Törmä, Päivi A1 - Trigo, Jorge Olmos A1 - Tristram, Frank A1 - Tsitsas, Nikolaos L. A1 - Vallée, Renaud A1 - Vynck, Kevin A1 - Weiss, Thomas A1 - Wiecha, Peter A1 - Wriedt, Thomas A1 - Yannopapas, Vassilios A1 - Yurkin, Maxim A. A1 - Zouros, Grigorios P. T1 - T-matrix representation of optical scattering response: Suggestion for a data format JF - J. Quant. Spectrosc. Radiat. Transf. Y1 - 2025 U6 - https://doi.org/10.1016/j.jqsrt.2024.109310 VL - 333 SP - 109310 ER - TY - GEN A1 - Ternes, Thomas A1 - Bauer, Karl-Heinz A1 - Brauer, Frank A1 - Drewes, Jürgen A1 - Jewell, Kevin A1 - Joss, Adriano A1 - Oehlmann, Jörg A1 - Radtke, Michael A1 - Schulte-Oehlmann, Ulrike A1 - Schwartz, Thomas A1 - Seel, Peter A1 - Völker, Jeanette A1 - Weber, Lilo A1 - Weber, Marcus T1 - Handlungsempfehlung zur integrativen Bewertung der weitergehenden Abwasserbehandlung von kommunalen Kläranlagen T2 - DWA-Themen N2 - Der DWA-Themenband beschreibt ein Konzept zur weitergehenden Abwasserbehandlung für die Bewertung von Aufbereitungsverfahren, sowohl in einer Pilotphase zur Auswahl von Verfahrensoptionen als auch für die Bewertung großtechnischer Anlagen. Emissionsseitig basiert das Konzept auf bereits regulatorisch definierten Parametern wie anorganischen Stickstoff-Verbindungen oder Phosphat sowie auf neuen noch nicht in der Abwasserverordnung regulierten Parametern. Die immissionsseitige Betrachtung erfolgt auf Basis der rechtlich durch die Europäische Wasserrahmenrichtlinie und andere Anforderungen bindenden Instrumente. Hierfür werden spezifische Vorgehensweisen vorgeschlagen. Anhand zweier ausgewählter Praxisbeispiele wird deutlich, dass es zur Bewertung der Verfahrensoptionen an einem Standort dienlich ist, ausgewählte Reduktionen bzw. Entfernungen von Stoffen, Organismen und Effekten zu bestimmen. Y1 - 2023 VL - T1/2023 PB - DWA ER - TY - JOUR A1 - Abbas, Aennes A1 - Schneider, Ilona A1 - Bollmann, Anna A1 - Funke, Jan A1 - Oehlmann, Jörg A1 - Prasse, Carsten A1 - Schulte-Oehlmann, Ulrike A1 - Seitz, Wolfram A1 - Ternes, Thomas A1 - Weber, Marcus A1 - Wesely, Henning A1 - Wagner, Martin T1 - What you extract is what you see: Optimising the preparation of water and wastewater samples for in vitro bioassays JF - Water Research N2 - The assessment of water quality is crucial for safeguarding drinking water resources and ecosystem integrity. To this end, sample preparation and extraction is critically important, especially when investigating emerging contaminants and the toxicity of water samples. As extraction methods are rarely optimised for bioassays but rather adopted from chemical analysis, this may result in a misrepresentation of the actual toxicity. In this study, surface water, groundwater, hospital and municipal wastewater were used to characterise the impacts of common sample preparation techniques (acidification, filtration and solid phase extraction (SPE)) on the outcomes of eleven in vitro bioassays. The latter covered endocrine activity (reporter gene assays for estrogen, androgen, aryl-hydrocarbon, retinoic acid, retinoid X, vitamin D, thyroid receptor), mutagenicity (Ames fluctuation test), genotoxicity (umu test) and cytotoxicity. Water samples extracted using different SPE sorbents (Oasis HLB, Supelco ENVI-Carb+, Telos C18/ENV) at acidic and neutral pH were compared for their performance in recovering biological effects. Acidification, commonly used for stabilisation, significantly altered the endocrine activity and toxicity of most (waste)water samples. Sample filtration did not affect the majority of endpoints but in certain cases affected the (anti-)estrogenic and dioxin-like activities. SPE extracts (10.4 × final concentration), including WWTP effluents, induced significant endocrine effects that were not detected in aqueous samples (0.63 × final concentration), such as estrogenic, (anti-)androgenic and dioxin-like activities. When ranking the SPE methods using multivariate Pareto optimisation an extraction with Telos C18/ENV at pH 7 was most effective in recovering toxicity. At the same time, these extracts were highly cytotoxic masking the endpoint under investigation. Compared to that, extraction at pH 2.5 enriched less cytotoxicity. In summary, our study demonstrates that sample preparation and extraction critically affect the outcome of bioassays when assessing the toxicity of water samples. Depending on the water matrix and the bioassay, these methods need to be optimised to accurately assess water quality. Y1 - 2019 U6 - https://doi.org/10.1016/j.watres.2018.12.049 VL - 152 SP - 47 EP - 60 ER - TY - CHAP A1 - Werdehausen, Daniel A1 - Staude, Isabelle A1 - Burger, Sven A1 - Petschulat, Jörg A1 - Scharf, Toralf A1 - Pertsch, Thomas A1 - Decker, Manuel T1 - Using effective medium theories to design tailored nanocomposite materials for optical systems T2 - Proc. SPIE Y1 - 2018 U6 - https://doi.org/10.1117/12.2320525 VL - 10745 SP - 107450H ER - TY - JOUR A1 - Dickmann, Frank A1 - Falkner, Jürgen A1 - Gunia, Wilfried A1 - Hampe, Jochen A1 - Hausmann, Michael A1 - Herrmann, Alexander A1 - Kepper, Nick A1 - Knoch, Tobias A1 - Lauterbach, Svenja A1 - Lippert, Jörg A1 - Peter, Kathrin A1 - Schmitt, Eberhard A1 - Schwardmann, Ulrich A1 - Solodenko, Juri A1 - Sommerfeld, Dietmar A1 - Steinke, Thomas A1 - Weisbecker, Anette A1 - Sax, Ulrich T1 - Solutions for biomedical grid computing – Case studies from the D-Grid project Services@MediGRID JF - Journal of Computational Science Y1 - 2011 UR - http://www.sciencedirect.com/science/article/pii/S1877750311000603 U6 - https://doi.org/10.1016/j.jocs.2011.06.006 VL - - IS - 0 ER - TY - JOUR A1 - Werdehausen, Daniel A1 - Staude, Isabelle A1 - Burger, Sven A1 - Petschulat, Jörg A1 - Scharf, Toralf A1 - Pertsch, Thomas A1 - Decker, Manuel T1 - Design rules for customizable optical materials based on nanocomposites JF - Opt. Mater. Express Y1 - 2018 U6 - https://doi.org/10.1364/OME.8.003456 VL - 8 SP - 3456 ER - TY - GEN A1 - Dentcheva, Darinka A1 - Möller, Andris A1 - Reeh, Peter A1 - Römisch, Werner A1 - Schultz, Rüdiger A1 - Schwarzbach, Gert A1 - Thomas, Jörg T1 - Optimale Blockauswahl bei der Kraftwerkseinsatzplanung N2 - The paper addresses the unit commitment problem in power plant operation planning. For a real power system comprising coal and gas fired thermal as well as pumped storage hydro plants a large-scale mixed integer optimization model for unit commitment is developed. Then primal and dual approaches to solving the optimization problem are presented and results of test runs are reported. T3 - ZIB-Report - SC-96-03 Y1 - 1996 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-2144 ER - TY - CHAP A1 - Grötschel, Martin A1 - Krumke, Sven A1 - Rambau, Jörg A1 - Winter, Thomas A1 - Zimmermann, Uwe ED - Grötschel, Martin ED - Krumke, Sven ED - Rambau, Jörg T1 - Combinatorial Online Optimization in Real Time T2 - Online Optimization of Large Scale Systems Y1 - 2001 SP - 679 EP - 704 PB - Springer ER - TY - CHAP A1 - Schneider, Jörg A1 - Gehr, Julius A1 - Linnert, Barry A1 - Röblitz, Thomas T1 - An Efficient Protocol for Reserving Multiple Grid Resources in Advance T2 - Proceedings of the 3$^rd$ CoreGRID Workshop on Grid Middleware Y1 - 2008 CY - Barcelona, Spain ER - TY - JOUR A1 - Heye, Katharina A1 - Becker, Dennis A1 - Lütke-Eversloh, Christian A1 - Durmaz, Vedat A1 - Ternes, Thomas A1 - Oetken, Matthias A1 - Oehlmann, Jörg T1 - Effects of carbamazepine and two of its metabolites on the non-biting midge Chironomus riparius in a sediment full life cycle toxicity test JF - Water Research N2 - The antiepileptic drug carbamazepine (CBZ) and its main metabolites carbamazepine-10,11-epoxide (EP-CBZ) and 10,11-dihydro-10,11-dihydroxy-carbamazepine (DiOH-CBZ) were chosen as test substances to assess chronic toxicity on the non-biting midge Chironomus riparius. All three substances were tested in a 40-day sediment full life cycle test (according to OECD 233) in which mortality, emergence, fertility, and clutch size were evaluated. In addition, these parameters were integrated into the population growth rate to reveal population relevant effects. With an LC50 of 0.203 mg/kg (time-weighted mean), the metabolite EP-CBZ was significantly more toxic than the parent substance CBZ (LC50: 1.11 mg/kg). Especially mortality, emergence, and fertility showed to be sensitive parameters under the exposure to CBZ and EP-CBZ. By using classical molecular dynamics (MD) simulations, the binding of CBZ to the ecdysone receptor was investigated as one possible mode of action but showed to be unlikely. The second metabolite DiOH-CBZ did not show any effects within the tested concentration rage (0.171 – 1.22 mg/kg). Even though CBZ was less toxic compared to EP-CBZ, CBZ is found in the environment at much higher concentrations and causes therefore a higher potential risk for sediment dwelling organisms compared to its metabolites. Nevertheless, the current study illustrates the importance of including commonly found metabolites into the risk assessment of parent substances. Y1 - 2016 VL - 98 SP - 19 EP - 27 ER - TY - GEN A1 - Grötschel, Martin A1 - Krumke, Sven A1 - Rambau, Jörg A1 - Winter, Thomas A1 - Zimmermann, Uwe T1 - Combinatorial Online Optimization in Real Time N2 - Optimization is the task of finding an optimum solution to a given problem. When the decision variables are discrete we speak of a combinatorial optimization problem. Such a problem is online when decisions have to be made before all data of the problem are known. And we speak of a real-time online problem when online decisions have to be computed within very tight time bounds. This paper surveys the are of combinatorial online and real-time optimization, it discusses, in particular, the concepts with which online and real-time algorithms can be analyzed. T3 - ZIB-Report - 01-16 KW - Online Optimization KW - Realtime Optimization KW - Competitive Analysis KW - Heuristics KW - Survey Y1 - 2001 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-6424 ER -