TY - JOUR A1 - Hege, Hans-Christian A1 - Benger, Werner A1 - Merzky, André A1 - Kasper, Friedbert A1 - Radke, Thomas A1 - Seidel, Edward T1 - Schwarze Löcher in Sicht - Immersive Überwachung und Steuerung von Remote-Simulationen JF - DFN-Mitteilungen Y1 - 2000 VL - 52 IS - 2 SP - 4 EP - 6 ER - TY - JOUR A1 - Hege, Hans-Christian T1 - Scaling study of pure SU(3) theory - the QCD-TARO collaboration JF - Nucl. Phys. B Proc. Suppl. Y1 - 1994 U6 - https://doi.org/10.1016/0920-5632(94)90358-1 VL - 34 SP - 246 EP - 252 ER - TY - CHAP A1 - Theisel, Holger A1 - Weinkauf, Tino A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Saddle Connectors - An Approach to Visualizing the Topological Skeleton of Complex 3D Vector Fields T2 - Proc. IEEE Visualization 2003 Y1 - 2003 U6 - https://doi.org/10.1109/VISUAL.2003.1250376 SP - 225 EP - 232 CY - Seattle ER - TY - JOUR A1 - Baum, Daniel A1 - Lindow, Norbert A1 - Hege, Hans-Christian A1 - Lepper, Verena A1 - Siopi, Tzulia A1 - Kutz, Frank A1 - Mahlow, Kristin A1 - Mahnke, Heinz-Eberhard T1 - Revealing hidden text in rolled and folded papyri JF - Applied Physics A N2 - Ancient Egyptian papyri are often folded, rolled up or kept as small packages, sometimes even sealed. Physically unrolling or unfolding these packages might severely damage them. We demonstrate a way to get access to the hidden script without physical unfolding by employing computed tomography and mathematical algorithms for virtual unrolling and unfolding. Our algorithmic approaches are combined with manual interaction. This provides the necessary flexibility to enable the unfolding of even complicated and partly damaged papyrus packages. In addition, it allows us to cope with challenges posed by the structure of ancient papyrus, which is rather irregular, compared to other writing substrates like metallic foils or parchment. Unfolding of packages is done in two stages. In the first stage, we virtually invert the physical folding process step by step until the partially unfolded package is topologically equivalent to a scroll or a papyrus sheet folded only along one fold line. To minimize distortions at this stage, we apply the method of moving least squares. In the second stage, the papyrus is simply flattened, which requires the definition of a medial surface. We have applied our software framework to several papyri. In this work, we present the results of applying our approaches to mockup papyri that were either rolled or folded along perpendicular fold lines. In the case of the folded papyrus, our approach represents the first attempt to address the unfolding of such complicated folds. Y1 - 2017 U6 - https://doi.org/10.1007/s00339-017-0808-6 VL - 123 IS - 3 SP - 171 ER - TY - GEN A1 - Baum, Daniel A1 - Lindow, Norbert A1 - Hege, Hans-Christian A1 - Lepper, Verena A1 - Siopi, Tzulia A1 - Kutz, Frank A1 - Mahlow, Kristin A1 - Mahnke, Heinz-Eberhard T1 - Revealing hidden text in rolled and folded papyri N2 - Ancient Egyptian papyri are often folded, rolled up or kept as small packages, sometimes even sealed. Physically unrolling or unfolding these packages might severely damage them. We demonstrate a way to get access to the hidden script without physical unfolding by employing computed tomography and mathematical algorithms for virtual unrolling and unfolding. Our algorithmic approaches are combined with manual interaction. This provides the necessary flexibility to enable the unfolding of even complicated and partly damaged papyrus packages. In addition, it allows us to cope with challenges posed by the structure of ancient papyrus, which is rather irregular, compared to other writing substrates like metallic foils or parchment. Unfolding of packages is done in two stages. In the first stage, we virtually invert the physical folding process step by step until the partially unfolded package is topologically equivalent to a scroll or a papyrus sheet folded only along one fold line. To minimize distortions at this stage, we apply the method of moving least squares. In the second stage, the papyrus is simply flattened, which requires the definition of a medial surface. We have applied our software framework to several papyri. In this work, we present the results of applying our approaches to mockup papyri that were either rolled or folded along perpendicular fold lines. In the case of the folded papyrus, our approach represents the first attempt to address the unfolding of such complicated folds. T3 - ZIB-Report - 17-02 KW - unfolding, papyri, computed tomography Y1 - 2017 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-61826 SN - 1438-0064 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Schaller, Jens A1 - Kertzscher, Ulrich A1 - Petz, Christoph A1 - Hege, Hans-Christian A1 - Spuler, Andreas T1 - Reproducibility of Image-Based Analysis of Cerebral Aneurysm Geometry and Hemodynamics: An In-Vitro Study of Magnetic Resonance Imaging, Computed Tomography, and Three-Dimensional Rotational Angiography JF - Journal of Neurological Surgery, Part A: Central European Neurosurgery Y1 - 2013 U6 - https://doi.org/10.1055/s-0033-1342937 VL - 74 IS - 5 SP - 294 EP - 302 ER - TY - CHAP A1 - Kähler, Ralf A1 - Cox, Donna A1 - Patterson, Robert A1 - Levy, Stuart A1 - Hege, Hans-Christian A1 - Abel, Tom ED - J. Moorhead, Robert ED - Gross, Markus ED - I. Joy, Kenneth T1 - Rendering The First Star in The Universe - A Case Study T2 - Proceedings of IEEE Visualization 2002 Y1 - 2002 U6 - https://doi.org/10.1109/VISUAL.2002.1183824 SP - 537 EP - 540 PB - IEEE Computer Society Press CY - Boston MA, USA ER - TY - GEN A1 - Hoerth, Rebecca M. A1 - Baum, Daniel A1 - Knötel, David A1 - Prohaska, Steffen A1 - Willie, Bettina M. A1 - Duda, Georg A1 - Hege, Hans-Christian A1 - Fratzl, Peter A1 - Wagermaier, Wolfgang T1 - Registering 2D and 3D Imaging Data of Bone during Healing N2 - Purpose/Aims of the Study: Bone’s hierarchical structure can be visualized using a variety of methods. Many techniques, such as light and electron microscopy generate two-dimensional (2D) images, while micro computed tomography (μCT) allows a direct representation of the three-dimensional (3D) structure. In addition, different methods provide complementary structural information, such as the arrangement of organic or inorganic compounds. The overall aim of the present study is to answer bone research questions by linking information of different 2D and 3D imaging techniques. A great challenge in combining different methods arises from the fact that they usually reflect different characteristics of the real structure. Materials and Methods: We investigated bone during healing by means of μCT and a couple of 2D methods. Backscattered electron images were used to qualitatively evaluate the tissue’s calcium content and served as a position map for other experimental data. Nanoindentation and X-ray scattering experiments were performed to visualize mechanical and structural properties. Results: We present an approach for the registration of 2D data in a 3D μCT reference frame, where scanning electron microscopies serve as a methodic link. Backscattered electron images are perfectly suited for registration into μCT reference frames, since both show structures based on the same physical principles. We introduce specific registration tools that have been developed to perform the registration process in a semi-automatic way. Conclusions: By applying this routine, we were able to exactly locate structural information (e.g. mineral particle properties) in the 3D bone volume. In bone healing studies this will help to better understand basic formation, remodeling and mineralization processes. T3 - ZIB-Report - 15-01 Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-53426 SN - 1438-0064 ER - TY - JOUR A1 - Hoerth, Rebecca M. A1 - Baum, Daniel A1 - Knötel, David A1 - Prohaska, Steffen A1 - Willie, Bettina M. A1 - Duda, Georg A1 - Hege, Hans-Christian A1 - Fratzl, Peter A1 - Wagermaier, Wolfgang T1 - Registering 2D and 3D Imaging Data of Bone during Healing JF - Connective Tissue Research Y1 - 2015 U6 - https://doi.org/10.3109/03008207.2015.1005210 VL - 56 IS - 2 SP - 133 EP - 143 PB - Taylor & Francis ER - TY - GEN A1 - Gowin, Wolfgang A1 - Saparin, Peter A1 - Felsenberg, Dieter A1 - Kurths, Jürgen A1 - Zaikin, Alexei A1 - Prohaska, Steffen A1 - Hege, Hans-Christian T1 - Regional Structural Skeletal Discordance Assessed by Measures of Complexity Y1 - 2002 ER - TY - CHAP A1 - Gladilin, Evgeny A1 - Zachow, Stefan A1 - Deuflhard, Peter A1 - Hege, Hans-Christian ED - Galloway, Robert T1 - Realistic prediction of individual facial emotion expressions for craniofacial surgery simulations T2 - Proc. SPIE medical Imaging 2003 Y1 - 2003 U6 - https://doi.org/10.1117/12.479584 VL - 5029 SP - 520 EP - 527 CY - San Diego, CA, USA ER - TY - CHAP A1 - Clasen, Malte A1 - Hege, Hans-Christian ED - Buhmann, Erich ED - Paar, Philip ED - Bishop, Ian ED - Lange, Eckart T1 - Realistic illumination of vegetation in real-time environments T2 - Trends in Real-Time Landscape Visualization and Participation Y1 - 2005 SP - 107 EP - 114 PB - Wichmann Verlag ER - TY - CHAP A1 - Colditz, Carsten A1 - Coconu, Liviu A1 - Deussen, Oliver A1 - Hege, Hans-Christian ED - Buhmann, Erich ED - Paar, Philip ED - Bishop, Ian ED - Lange, Eckart T1 - Real-time rendering of complex photorealistic landscapes using hybrid level-of-detail approaches T2 - Trends in Real-Time Landscape Visualization and Participation Y1 - 2005 SP - 97 EP - 106 PB - Wichmann Verlag ER - TY - CHAP A1 - Coconu, Liviu A1 - Deussen, Oliver A1 - Hege, Hans-Christian T1 - Real-time pen-and-ink illustration of landscapes T2 - NPAR '06: Proceedings of the 3rd International Symposium on Non-photorealistic Animation and Rendering Y1 - 2006 U6 - https://doi.org/10.1145/1124728.1124734 SP - 27 EP - 35 PB - ACM press CY - New York, NY, USA ER - TY - GEN A1 - Deuflhard, Peter A1 - Hege, Hans-Christian ED - Lepper, Verena ED - Deuflhard, Peter ED - Markschies, Christoph T1 - Raumtiefe in Malerei und Computergrafik T2 - Räume - Bilder - Kulturen N2 - Einführung: Die Tiefenwirkung dreidimensionaler Räume in einem zweidimensionalen Bild einzufangen, ist ein Faszinosum nahezu aller Kulturen der Menschheitsgeschichte. Der vorliegende Aufsatz folgt den Spuren dieses Faszinosums, vergleichend in der Malerei und der mathematisierten Computergrafik. Die Entdeckung der Zentralperspektive in der italienischen Renaissance zeigt bereits den engen Zusammenhang von Malerei und Mathematik. Auf der Suche nach Maltechniken, mit denen Raumtiefe bildnerisch dargestellt werden kann, beginnen wir in Kap. 2 mit einem chronologischen Gang durch verschiedene Epochen der europäischen Malerei. Hieraus abgeleitete Prinzipien, soweit sie im Rechner realisierbar scheinen, stellen wir in Kap. 3 am Beispiel moderner Methoden der mathematischen Visualisierung vor. Y1 - 2015 SN - 978-3-11-035993-0 SP - 33 EP - 46 PB - Walter De Gruyter ER - TY - CHAP A1 - Harth, Philipp A1 - Bast, Arco A1 - Troidl, Jakob A1 - Meulemeester, Bjorge A1 - Pfister, Hanspeter A1 - Beyer, Johanna A1 - Oberlaender, Marcel A1 - Hege, Hans-Christian A1 - Baum, Daniel T1 - Rapid Prototyping for Coordinated Views of Multi-scale Spatial and Abstract Data: A Grammar-based Approach T2 - Eurographics Workshop on Visual Computing for Biology and Medicine (VCBM) N2 - Visualization grammars are gaining popularity as they allow visualization specialists and experienced users to quickly create static and interactive views. Existing grammars, however, mostly focus on abstract views, ignoring three-dimensional (3D) views, which are very important in fields such as natural sciences. We propose a generalized interaction grammar for the problem of coordinating heterogeneous view types, such as standard charts (e.g., based on Vega-Lite) and 3D anatomical views. An important aspect of our web-based framework is that user interactions with data items at various levels of detail can be systematically integrated and used to control the overall layout of the application workspace. With the help of a concise JSON-based specification of the intended workflow, we can handle complex interactive visual analysis scenarios. This enables rapid prototyping and iterative refinement of the visual analysis tool in collaboration with domain experts. We illustrate the usefulness of our framework in two real-world case studies from the field of neuroscience. Since the logic of the presented grammar-based approach for handling interactions between heterogeneous web-based views is free of any application specifics, it can also serve as a template for applications beyond biological research. Y1 - 2023 U6 - https://doi.org/10.2312/vcbm.20231218 ER - TY - JOUR A1 - Akemi, K. A1 - deForcrand, Ph. A1 - Fujisaki, M. A1 - Hashimoto, T. A1 - Hege, Hans-Christian A1 - Hioki, S. A1 - Miyamura, O. A1 - Nakamura, A. A1 - Okuda, M. A1 - Stamatescu, I. O. A1 - Tago, Yoshio A1 - Takaishi, T. T1 - Quantum Chromodynamics Simulations on a Non-Dedicated Highly Parallel Computer JF - Comp. Phys. Comm Y1 - 1995 U6 - https://doi.org/10.1016/0010-4655(95)00082-Q VL - 90 SP - 201 EP - 214 ER - TY - JOUR A1 - Saparin, Peter A1 - Thomsen, Jesper A1 - Prohaska, Steffen A1 - Zaikin, Alexei A1 - Kurths, Jürgen A1 - Hege, Hans-Christian A1 - Gowin, Wolfgang T1 - Quantification of spatial structure of human proximal tibial bone biopsies using 3D measures of complexity JF - Acta Astronautica Y1 - 2005 U6 - https://doi.org/10.1016/j.actaastro.2005.01.007 VL - 56 IS - 9-12 SP - 820 EP - 830 ER - TY - CHAP A1 - Saparin, Peter A1 - Gowin, Wolfgang A1 - Zaikin, Alexei A1 - Thomsen, Jesper A1 - Prohaska, Steffen A1 - Hege, Hans-Christian A1 - Kurths, Jürgen T1 - Quantification of Changes in Spatial Structure of Human Bone Biopsies Using 3D Measures of Complexity T2 - 14th IAA Humans in Space Symposium Y1 - 2003 CY - Banff, Alberta, Canada ER - TY - JOUR A1 - Hashimoto, T. A1 - Hege, Hans-Christian T1 - QCD on the Massively Parallel Computer AP 1000 JF - Int. J. Mod. Phys. Y1 - 1993 U6 - https://doi.org/10.1142/S0129183193000975 VL - 4 IS - 6 SP - 1233 EP - 1253 ER - TY - JOUR A1 - Akemi, K. A1 - Forcrand, Ph. de A1 - Fujisaki, M. A1 - Hashimoto, T. A1 - Hege, Hans-Christian A1 - Hioki, S. A1 - Makino, J. A1 - Miyamura, O. A1 - Nakamura, A. A1 - Okuda, M. A1 - Stamatescu, I. O. A1 - Tago, Yoshio A1 - Takaishi, T. T1 - QCD on the Highly Parallel Computer AP 1000 JF - Nucl. Phys. B Proc. Suppl. 26 Y1 - 1992 U6 - https://doi.org/10.1016/0920-5632(92)90358-Y SP - 644 EP - 646 ER - TY - CHAP A1 - Hege, Hans-Christian A1 - Hutanu, Andrei A1 - Kähler, Ralf A1 - Merzky, André A1 - Radke, Thomas A1 - Seidel, Edward A1 - Ullmer, Brygg T1 - Progressive Retrieval and Hierarchical Visualization of Large Remote Data T2 - Proceedings of the 2003 Workshop on Adaptive Grid Middleware Y1 - 2003 SP - 60 EP - 72 ER - TY - GEN A1 - Günther, Tobias A1 - Kuhn, Alexander A1 - Hege, Hans-Christian A1 - Gross, Markus A1 - Theisel, Holger T1 - Progressive Monte-Carlo Rendering of Atmospheric Flow Features Across Scales T2 - 69th Annual Meeting of the APS Division of Fluid Dynamics, Gallery of Fluid Motion, Nov 20-22, 2016, Portland, OR, USA. N2 - To improve existing weather prediction and reanalysis capabilities, high-resolution and multi-modal climate data becomes an increasingly important topic. The advent of increasingly dense numerical simulation of atmospheric phenomena, provides new means to better understand dynamic processes and to visualize structural flow patterns that remain hidden otherwise. In the presented illustrations we demonstrate an advanced technique to visualize multiple scales of dense flow fields and Lagrangian patterns therein, simulated by state-of-the-art simulation models for each scale. They provide a deeper insight into the structural differences and patterns that occur on each scale and highlight the complexity of flow phenomena in our atmosphere. Y1 - 2016 U6 - https://doi.org/10.1103/APS.DFD.2016.GFM.P0030 ER - TY - JOUR A1 - Günther, Tobias A1 - Kuhn, Alexander A1 - Hege, Hans-Christian A1 - Gross, Markus A1 - Theisel, Holger T1 - Progressive Monte Carlo rendering of atmospheric flow features across scales JF - Physical Review Fluids N2 - To improve existing weather prediction and reanalysis capabilities, high-resolution and multi-modal climate data becomes an increasingly important topic. The advent of increasingly dense numerical simulation of atmospheric phenomena, provides new means to better understand dynamic processes and to visualize structural flow patterns that remain hidden otherwise. In the presented illustrations we demonstrate an advanced technique to visualize multiple scales of dense flow fields and Lagrangian patterns therein, simulated by state-of-the-art simulation models for each scale. They provide a deeper insight into the structural differences and patterns that occur on each scale and highlight the complexity of flow phenomena in our atmosphere. This paper is associated with a poster winner of a 2016 APS/DFD Milton van Dyke Award for work presented at the DFD Gallery of Fluid Motion. The original poster is available from the Gallery of Fluid Motion, https://doi.org/10.1103/APS.DFD.2016.GFM.P0030 Y1 - 2017 U6 - https://doi.org/10.1103/PhysRevFluids.2.090502 VL - 2 SP - 09050-1 EP - 09050-3 ER - TY - CHAP A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebaß, Martin T1 - Progress Towards a Combined MRI/Hyperthermia System T2 - Proceedings Second International Congress HIGH CARE 2000 Y1 - 2000 CY - Bochum ER - TY - JOUR A1 - Hege, Hans-Christian T1 - Problems and Solutions: Product of Chebyshev Polynomials JF - Orthogonal Polynomials and Special Functions Y1 - 1996 VL - 6 (2) SP - 12 ER - TY - JOUR A1 - Pöthkow, Kai A1 - Weber, Britta A1 - Hege, Hans-Christian T1 - Probabilistic Marching Cubes JF - Computer Graphics Forum Y1 - 2011 U6 - https://doi.org/10.1111/j.1467-8659.2011.01942.x VL - 30 IS - 3 SP - 931 EP - 940 ER - TY - JOUR A1 - Petz, Christoph A1 - Pöthkow, Kai A1 - Hege, Hans-Christian T1 - Probabilistic Local Features in Uncertain Vector Fields with Spatial Correlation JF - Computer Graphics Forum Y1 - 2012 VL - 31 IS - 3 SP - 1045 EP - 1054 ER - TY - JOUR A1 - Pöthkow, Kai A1 - Hege, Hans-Christian T1 - Positional Uncertainty of Isocontours: Condition Analysis and Probabilistic Measures JF - IEEE Transactions on Visualization and Computer Graphics Y1 - 2011 U6 - https://doi.org/10.1109/TVCG.2010.247 VL - 17 IS - 10 SP - 1393 EP - 1406 ER - TY - CHAP A1 - Kuß, Anja A1 - Hege, Hans-Christian A1 - Krofczik, Sabine A1 - Börner, Jana T1 - Pipeline for the creation of surface-based averaged brain atlases T2 - Proceedings of WSCG 2007 - the 15-th International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision Y1 - 2007 VL - 15 SP - 17 EP - 24 CY - Plzen, Czech Republic ER - TY - JOUR A1 - Lindow, Norbert A1 - Baum, Daniel A1 - Hege, Hans-Christian T1 - Perceptually Linear Parameter Variations JF - Computer Graphics Forum Y1 - 2012 U6 - https://doi.org/10.1111/j.1467-8659.2012.03054.x target VL - 31 IS - 2 SP - 535 EP - 544 ER - TY - GEN A1 - Wiebel, Alexander A1 - Vos, Frans M. A1 - Hege, Hans-Christian T1 - Perception-Oriented Picking of Structures in Direct Volumetric Renderings N2 - Radiologists from all application areas are trained to read slice-based visualizations of 3D medical image data. Despite the numerous examples of sophisticated three-dimensional renderings, especially all variants of direct volume rendering, such methods are often considered not very useful by radiologists who prefer slice-based visualization. Just recently there have been attempts to bridge this gap between 2D and 3D renderings. These attempts include specialized techniques for volume picking that result in repositioning slices. In this paper, we present a new volume picking technique that, in contrast to previous work, does not require pre-segmented data or metadata. The positions picked by our method are solely based on the data itself, the transfer function and, most importantly, on the way the volumetric rendering is perceived by viewers. To demonstrate the usefulness of the proposed method we apply it for automatically repositioning slices in an abdominal MRI scan, a data set from a flow simulation and a number of other volumetric scalar fields. Furthermore we discuss how the method can be implemented in combination with various different volumetric rendering techniques. T3 - ZIB-Report - 11-45 KW - DVR KW - picking KW - pointing KW - direct volume rendering Y1 - 2011 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-14343 SN - 1438-0064 ER - TY - CHAP A1 - Wust, Peter A1 - Nadobny, Jacek A1 - Gellermann, Johanna A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Felix, Roland T1 - Patient Models and Algorithms for Hyperthermia Planning T2 - Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology ESHO-97 Y1 - 1997 ER - TY - CHAP A1 - Shi, Kuangyu A1 - Theisel, Holger A1 - Weinkauf, Tino A1 - Hauser, Helwig A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Path line oriented topology for periodic 2D time-dependent vector fields T2 - Proc. Eurographics / IEEE VGTC Symposium on Visualization Y1 - 2006 SP - 139 EP - 146 CY - Lisbon, Portugal ER - TY - CHAP A1 - Shi, Kuangyu A1 - Theisel, Holger A1 - Hauser, Helwig A1 - Weinkauf, Tino A1 - Hege, Hans-Christian A1 - Seidel, Hans-Peter T1 - Path Line Attributes - an Information Visualization Approach to Analyzing the Dynamic Behavior of 3D Time-Dependent Flow Fields T2 - Topology-Based Methods in Visualization II Y1 - 2009 U6 - https://doi.org/10.1007/978-3-540-88606-8_6 SP - 75 EP - 88 PB - Springer CY - Berlin ER - TY - CHAP A1 - Wunderling, Roland A1 - Grammel, Martin A1 - Hege, Hans-Christian T1 - Parallele LU-Zerlegung großer, unsymmetrischer, dünn besetzter Matrizen bei hohen Kommunikationslatenzen T2 - GI/ITG-Workshop, Sept.1994, Mitteilungen der Fachgruppe PARS der Gesellschaft für Informatik (GI) Y1 - 1994 VL - 13 SP - 191 EP - 200 CY - Potsdam ER - TY - CHAP A1 - Zöckler, Malte A1 - Stalling, Detlev A1 - Hege, Hans-Christian T1 - Parallel Line Integral Convolution T2 - Proc. First Eurographics Workshop on Parallel Graphics and Visualization Y1 - 1996 U6 - https://doi.org/10.1016/S0167-8191(97)00039-2 SP - 111 EP - 128 CY - Bristol, U.K. ER - TY - CHAP A1 - Bonneau, Georges-Pierre A1 - Hege, Hans-Christian A1 - Johnson, Chris R. A1 - Oliveira, Manuel M. A1 - Potter, Kristin A1 - Rheingans, Penny A1 - Schultz, Thomas T1 - Overview and State-of-the-Art of Uncertainty Visualization T2 - Scientific Visualization - Uncertainty, Multifield, Biomedical, and Scalable Visualization N2 - The goal of visualization is to effectively and accurately communicate data. Visualization research has often overlooked the errors and uncertainty which accompany the scientific process and describe key characteristics used to fully understand the data. The lack of these representations can be attributed, in part, to the inherent difficulty in defining, characterizing, and controlling this uncertainty, and in part, to the difficulty in including additional visual metaphors in a well designed, potent display. However, the exclusion of this information cripples the use of visualization as a decision making tool due to the fact that the display is no longer a true representation of the data. This systematic omission of uncertainty commands fundamental research within the visualization community to address, integrate, and expect uncertainty information. In this chapter, we outline sources and models of uncertainty, give an overview of the state-of-the-art, provide general guidelines, outline small exemplary applications, and finally, discuss open problems in uncertainty visualization. Y1 - 2014 SN - 978-1-4471-6496-8 U6 - https://doi.org/10.1007/978-1-4471-6497-5_1 SP - 3 EP - 27 PB - Springer ER - TY - JOUR A1 - Willie, Bettina M. A1 - Pap, Thomas A1 - Perka, Carsten A1 - Schmidt, Carsten Oliver A1 - Eckstein, Felix A1 - Arampatzis, Adamantios A1 - Hege, Hans-Christian A1 - Madry, Henning A1 - Vortkamp, Andrea A1 - Duda, Georg T1 - OVERLOAD – Rolle der Gelenküberlastung in der primären Arthrose – Die Krankheitsprogression verstehen und vermeiden JF - Zeitschrift für Rheumatologie N2 - Intakte Gelenke sind eine Voraussetzung für das Funktionieren des Skeletts und die Mobilität im Lebensalltag. Ein gesunder Bewegungsapparat ist die Grundlage für die Funktionsfähigkeit des Herz-Kreislauf-Systems wie auch der Immunabwehr. Bewegungs- und Physiotherapie sowie verschiedene Formen der Patientenaktivität stellen essenzielle klinische Ansätze in der Behandlung von neurodegenerativen Erkrankungen, Schlaganfall, Diabetes und Krebs dar. Kommt es zu degenerativen Veränderungen von Gelenken, bedeutet dies eine wesentliche Beeinträchtigung der Mobilität. Nächtliche Schmerzen und Schlafstörungen treten in fortgeschrittenen Stadien auf und sind besonders belastend. Arthrose wird auch als degenerative Gelenkerkrankung bezeichnet. Sie geht mit Veränderungen in der Struktur und Zusammensetzung des Gelenkknorpels wie auch des verkalkten Knorpels, der subchondralen Kortikalis, der subchondralen Spongiosa, des Meniskus, der Gelenkkapsel und der Synovialis einher, was schließlich zur Degeneration dieser Gewebe führt, aus denen sich die Synovialgelenke zusammensetzen. Y1 - 2015 U6 - https://doi.org/10.1007/s00393-014-1561-2 VL - 74 SP - 618 EP - 621 ER - TY - JOUR A1 - Willie, Bettina M. A1 - Pap, Thomas A1 - Perka, Carsten A1 - Schmidt, Carsten Oliver A1 - Eckstein, Felix A1 - Arampatzis, Adamantios A1 - Hege, Hans-Christian A1 - Madry, Henning A1 - Vortkamp, Andrea A1 - Duda, Georg T1 - OVERLOAD of joints and its role in osteoarthritis - Towards understanding and preventing progression of primary osteoarthritis JF - Zeitschrift für Rheumatologie N2 - Intact joints are necessary for skeletal function and mobility in daily life. A healthy musculoskeletal system is the basis for a functional cardiovascular system as well as an intact immune system. Locomotion, physiotherapy, and various forms of patient activity are essential clinical therapies used in the treatment of neurodegeneration, stroke, diabetes, and cancer. Mobility is substantially impaired with degeneration of joints and, in advanced stages, nighttime pain and sleep disturbance are particularly cumbersome. Osteoarthritis (OA) is also known as degenerative joint disease. OA involves structural and compositional changes in the articular cartilage, as well as in the calcified cartilage, subchondral cortical bone, subchondral cancellous bone, meniscus, joint capsular tissue, and synovium; which eventually lead to degeneration of these tissues comprising synovial joints. Y1 - 2015 U6 - https://doi.org/10.1007/s00393-014-1561-2 VL - 76 IS - Suppl. 1 SP - 1 EP - 4 ER - TY - CHAP A1 - Ritter, Zully A1 - Prohaska, Steffen A1 - Brand, R. A1 - Friedmann, A. A1 - Hege, Hans-Christian A1 - Goebbels, Jürgen A1 - Felsenberg, Dieter T1 - Osteocytes number and volume in osteoporotic and in healthy bone biopsies analysed using Synchrotron CT: a pilot study T2 - Proc. ISB 2011 Y1 - 2011 ER - TY - JOUR A1 - Hermann, Gunter A1 - Pohl, Vincent A1 - Tremblay, Jean Christophe A1 - Paulus, Beate A1 - Hege, Hans-Christian A1 - Schild, Axel T1 - ORBKIT – A modular Python toolbox for cross-platform post-processing of quantum chemical wavefunction data JF - Journal of Computational Chemistry N2 - ORBKIT is a toolbox for postprocessing electronic structure calculations based on a highly modular and portable Python architecture. The program allows computing a multitude of electronic properties of molecular systems on arbitrary spatial grids from the basis set representation of its electronic wave function, as well as several grid-independent properties. The required data can be extracted directly from the standard output of a large number of quantum chemistry programs. ORBKIT can be used as a standalone program to determine standard quantities, for example, the electron density, molecular orbitals, and derivatives thereof. The cornerstone of ORBKIT is its modular structure. The existing basic functions can be arranged in an individual way and can be easily extended by user-written modules to determine any other derived quantity. ORBKIT offers multiple output formats that can be processed by common visualization tools (VMD, Molden, etc.). Additionally, ORBKIT offers routines to order molecular orbitals computed at different nuclear configurations according to their electronic character and to interpolate the wavefunction between these configurations. The program is open-source under GNU-LGPLv3 license and freely available at https://github.com/orbkit/orbkit/. This article provides an overview of ORBKIT with particular focus on its capabilities and applicability, and includes several example calculations. Y1 - 2016 U6 - https://doi.org/10.1002/jcc.24358 VL - 37 IS - 16 SP - 1511 EP - 1520 ER - TY - JOUR A1 - Zeilhofer, Hans-Florian A1 - Hege, Hans-Christian T1 - Operieren im Medizin-Grid JF - DFN-Mitteilungen, Heft 60 Y1 - 2002 SP - 19 EP - 20 ER - TY - CHAP A1 - Kuß, Anja A1 - Prohaska, Steffen A1 - Meyer, Björn A1 - Rybak, Jürgen A1 - Hege, Hans-Christian T1 - Ontology-Based Visualization of Hierarchical Neuroanatomical Structures T2 - Proceedings of the Eurographics Workshop on Visual Computing for Biomedicine VCBM 2008 Y1 - 2008 SP - 177 EP - 184 ER - TY - GEN A1 - Grammel, Martin A1 - Hege, Hans-Christian A1 - Wunderling, Roland T1 - On the Impact of Communication Latencies on Distributed Sparse LU Factorization. N2 - Sparse LU factorization offers some potential for parallelism, but at a level of very fine granularity. However, most current distributed memory MIMD architectures have too high communication latencies for exploiting all parallelism available. To cope with this, latencies must be avoided by coarsening the granularity and by message fusion. However, both techniques limit the concurrency, thereby reducing the scalability. In this paper, an implementation of a parallel LU decomposition algorithm for linear programming bases is presented for distributed memory parallel computers with noticable communication latencies. Several design decisions due to latencies, including data distribution and load balancing techniques, are discussed. An approximate performance model is set up for the algorithm, which allows to quantify the impact of latencies on its performance. Finally, experimental results for an Intel iPSC/860 parallel computer are reported and discussed. T3 - ZIB-Report - SC-93-28 Y1 - 1993 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-1245 ER - TY - GEN A1 - Kasten, Jens A1 - Hotz, Ingrid A1 - Noack, Bernd A1 - Hege, Hans-Christian ED - Pascucci, Valerio ED - Tricoche, Xavier ED - Hagen, Hans ED - Tierny, Julien T1 - On the Extraction of Long-living Features in Unsteady Fluid Flows T2 - Topological Methods in Data Analysis and Visualization Y1 - 2011 SN - 978-3-642-15013-5 U6 - https://doi.org/10.1007/978-3-642-15014-2_10 SP - 115 EP - 126 PB - Springer CY - Berlin ER - TY - GEN A1 - Kasten, Jens A1 - Hotz, Ingrid A1 - Hege, Hans-Christian ED - Peikert, Ronald ED - Hauser, Helwig ED - Carr, Hamish ED - Fuchs, Raphael T1 - On the Elusive Concept of Lagrangian Coherent Structures T2 - Topological Methods in Data Analysis and Visualization II Y1 - 2012 U6 - https://doi.org/10.1007/978-3-642-23175-9_14 SP - 207 EP - 220 PB - Springer ER - TY - CHAP A1 - Gladilin, Evgeny A1 - Zachow, Stefan A1 - Deuflhard, Peter A1 - Hege, Hans-Christian T1 - On constitutive modeling of soft tissue for the long-term prediction of cranio-maxillofacial surgery outcome T2 - International Congress Series, CARS2003, Computer Assisted Radiology and Surgery, Proceedings of the 17th International Congress and Exhibition Y1 - 2003 U6 - https://doi.org/10.1016/S0531-5131(03)00500-4 VL - 1256 SP - 343 EP - 348 ER - TY - JOUR A1 - Kainmüller, Dagmar A1 - Lamecker, Hans A1 - Heller, Markus O. A1 - Weber, Britta A1 - Hege, Hans-Christian A1 - Zachow, Stefan T1 - Omnidirectional Displacements for Deformable Surfaces JF - Medical Image Analysis Y1 - 2013 U6 - https://doi.org/10.1016/j.media.2012.11.006 VL - 17 IS - 4 SP - 429 EP - 441 PB - Elsevier ER - TY - CHAP A1 - Kuhn, Alexander A1 - Hege, Hans-Christian T1 - Object-based visualization and evaluation of cloud-resolving simulations T2 - Book of Abstracts, SCCS 2017 – Scaling Cascades in Complex Systems, Mar 27-29, 2017, Berlin, Germany N2 - Recent advances in high-resolution, cloud resolving simulation models pose several challenges towards respective analysis methodologies. To enable efficient comparison and validation of such models efficient, scalable, and informative diagnostic procedures are mandatory. In this talk, an object-based evaluation scheme based on the notion of scalar field topology will be presented. The presentation will cover the application of topological clustering procedures for object identification, tracking, and the retrieval of object-based statistics. The pro-posed methodology is shown to enable an advanced in-depth evaluation and visualization of high cloud-resolving models. Using a newly developed large-scale high-resolution model (i.e., HD(CP)2 ICON), it will be demonstrated that the presented procedures are applicable to assess the model performance compared to measurements (e.g., radar, satellite) and standard operational models (COSMO) at different domains and spatial scales. Y1 - 2017 ER - TY - CHAP A1 - Beck, Rudolf A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebaß, Martin A1 - Stalling, Detlev ED - Hege, Hans-Christian ED - Polthier, Konrad T1 - Numerical Algorithms and Visualization in Medical Treatment Planning T2 - Visualization and Mathematics 1997 Y1 - 1996 SP - 303 EP - 328 PB - Springer, Heidelberg ER - TY - JOUR A1 - Pöthkow, Kai A1 - Hege, Hans-Christian T1 - Nonparametric Models for Uncertainty Visualization JF - Computer Graphics Forum Y1 - 2013 U6 - https://doi.org/10.1111/cgf.12100 target VL - 32 IS - 3 SP - 131 EP - 140 ER - TY - CHAP A1 - Hanik, Martin A1 - Hege, Hans-Christian A1 - Hennemuth, Anja A1 - von Tycowicz, Christoph T1 - Nonlinear Regression on Manifolds for Shape Analysis using Intrinsic Bézier Splines T2 - Proc. Medical Image Computing and Computer Assisted Intervention (MICCAI) N2 - Intrinsic and parametric regression models are of high interest for the statistical analysis of manifold-valued data such as images and shapes. The standard linear ansatz has been generalized to geodesic regression on manifolds making it possible to analyze dependencies of random variables that spread along generalized straight lines. Nevertheless, in some scenarios, the evolution of the data cannot be modeled adequately by a geodesic. We present a framework for nonlinear regression on manifolds by considering Riemannian splines, whose segments are Bézier curves, as trajectories. Unlike variational formulations that require time-discretization, we take a constructive approach that provides efficient and exact evaluation by virtue of the generalized de Casteljau algorithm. We validate our method in experiments on the reconstruction of periodic motion of the mitral valve as well as the analysis of femoral shape changes during the course of osteoarthritis, endorsing Bézier spline regression as an effective and flexible tool for manifold-valued regression. Y1 - 2020 U6 - https://doi.org/10.1007/978-3-030-59719-1_60 SP - 617 EP - 626 PB - Springer International Publishing CY - Cham ER - TY - CHAP A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Hege, Hans-Christian A1 - Wust, Peter A1 - Felix, Roland A1 - Deuflhard, Peter T1 - New Features of HyperPlan, a Hyperthermia Planning System T2 - Proc. Hyperthermia in Clincal Oncology Y1 - 1998 SP - 16 CY - Venice ER - TY - JOUR A1 - Ziegler, Günter M. A1 - Hege, Hans-Christian A1 - Duda, Georg T1 - Neue Bilder für die Medizin? JF - DFN-Mitteilungen Y1 - 2005 VL - 13(3) SP - 163 EP - 167 ER - TY - CHAP A1 - Petz, Christoph A1 - Prohaska, Steffen A1 - Goubergrits, Leonid A1 - Kertzscher, Ulrich A1 - Hege, Hans-Christian T1 - Near-Wall Flow Visualization in Flattened Surface Neighborhoods T2 - Proc. Simulation and Visualization 2008 Y1 - 2008 UR - http://www.simvis.org/Tagung2008/sv-proceedings.html SP - 93 EP - 105 CY - Magdeburg, Germany ER - TY - JOUR A1 - Heller, Markus O. A1 - Matziolis, Georg A1 - König, Christian A1 - Taylor, William R. A1 - Hinterwimmer, S. A1 - Graichen, H. A1 - Hege, Hans-Christian A1 - Bergmann, G. A1 - Perka, Carsten A1 - Duda, G. N. T1 - Muskuloskelettale Biomechanik des Kniegelenks - Grundlagen für die präoperative Planung von Umstellung und Gelenkersatz JF - Der Orthopäde Y1 - 2007 U6 - https://doi.org/10.1007/s00132-007-1115-2 VL - 36 IS - 7 SP - 628 EP - 634 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Hellmeier, Florian A1 - Bruening, Jan Joris A1 - Spuler, Andreas A1 - Hege, Hans-Christian A1 - Voss, Samuel A1 - Janiga, Gábor A1 - Saalfeld, Sylvia A1 - Beuing, Oliver A1 - Berg, Philipp T1 - Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Uncertainty Quantification of Geometric Rupture Risk Parameters JF - BioMedical Engineering OnLine N2 - Background Geometric parameters have been proposed for prediction of cerebral aneurysm rupture risk. Predicting the rupture risk for incidentally detected unruptured aneurysms could help clinicians in their treatment decision. However, assessment of geometric parameters depends on several factors, including the spatial resolution of the imaging modality used and the chosen reconstruction procedure. The aim of this study was to investigate the uncertainty of a variety of previously proposed geometric parameters for rupture risk assessment, caused by variability of reconstruction procedures. Materials 26 research groups provided segmentations and surface reconstructions of five cerebral aneurysms as part of the Multiple Aneurysms AnaTomy CHallenge (MATCH) 2018. 40 dimensional and non-dimensional geometric parameters, describing aneurysm size, neck size, and irregularity of aneurysm shape, were computed. The medians as well as the absolute and relative uncertainties of the parameters were calculated. Additionally, linear regression analysis was performed on the absolute uncertainties and the median parameter values. Results A large variability of relative uncertainties in the range between 3.9 and 179.8% was found. Linear regression analysis indicates that some parameters capture similar geometric aspects. The lowest uncertainties < 6% were found for the non-dimensional parameters isoperimetric ratio, convexity ratio, and ellipticity index. Uncertainty of 2D and 3D size parameters was significantly higher than uncertainty of 1D parameters. The most extreme uncertainties > 80% were found for some curvature parameters. Conclusions Uncertainty analysis is essential on the road to clinical translation and use of rupture risk prediction models. Uncertainty quantification of geometric rupture risk parameters provided by this study may help support development of future rupture risk prediction models. Y1 - 2019 U6 - https://doi.org/10.1186/s12938-019-0657-y VL - 18 IS - 35 ER - TY - JOUR A1 - Vohra, Sumit Kumar A1 - Herrera, Kristian A1 - Tavhelidse-Suck, Tinatini A1 - Knoblich, Simon A1 - Seleit, Ali A1 - Boulanger-Weill, Jonathan A1 - Chambule, Sydney A1 - Aspiras, Ariel A1 - Santoriello, Cristina A1 - Randlett, Owen A1 - Wittbrodt, Joachim A1 - Aulehla, Alexander A1 - Lichtman, Jeff W. A1 - Fishman, Mark A1 - Hege, Hans-Christian A1 - Baum, Daniel A1 - Engert, Florian A1 - Isoe, Yasuko T1 - Multi-species community platform for comparative neuroscience in teleost fish N2 - Studying neural mechanisms in complementary model organisms from different ecological niches in the same animal class can leverage the comparative brain analysis at the cellular level. To advance such a direction, we developed a unified brain atlas platform and specialized tools that allowed us to quantitatively compare neural structures in two teleost larvae, medaka (Oryzias latipes) and zebrafish (Danio rerio). Leveraging this quantitative approach we found that most brain regions are similar but some subpopulations are unique in each species. Specifically, we confirmed the existence of a clear dorsal pallial region in the telencephalon in medaka lacking in zebrafish. Further, our approach allows for extraction of differentially expressed genes in both species, and for quantitative comparison of neural activity at cellular resolution. The web-based and interactive nature of this atlas platform will facilitate the teleost community’s research and its easy extensibility will encourage contributions to its continuous expansion. Y1 - 2024 U6 - https://doi.org/10.1101/2024.02.14.580400 ER - TY - CHAP A1 - Kainmüller, Dagmar A1 - Lamecker, Hans A1 - Zachow, Stefan A1 - Heller, Markus O. A1 - Hege, Hans-Christian T1 - Multi-Object Segmentation with Coupled Deformable Models T2 - Proc. Medical Image Understanding and Analysis Y1 - 2008 SP - 34 EP - 38 ER - TY - JOUR A1 - Hashimoto, T. A1 - Hege, Hans-Christian T1 - Monte Carlo Renormalization Study at Large beta in the Confinement Region JF - Nuclear Phys. B. Proc. Suppl. Y1 - 1993 U6 - https://doi.org/10.1016/0920-5632(93)90263-6 VL - 30 SP - 517 EP - 520 ER - TY - JOUR A1 - Lacarelle, Arnaud A1 - P. Moeck, Jonas A1 - Paschereit, Christian A1 - Gelbert, Gregor A1 - King, Rudibert A1 - M. Luchtenburg, Dirk A1 - Noack, Bernd R. A1 - Kasten, Jens A1 - Hege, Hans-Christian T1 - Modeling a Fuel/Air Mixing to Control the Pressure Pulsations and NOx Emissions in a Lean Premixed Combustor JF - Active Flow Control II Y1 - 2010 U6 - https://doi.org/10.1007/978-3-642-11735-0_20 VL - 108 SP - 307 EP - 321 PB - Springer, Berlin ER - TY - CHAP A1 - Neubert, Kerstin A1 - Lamecker, Hans A1 - Hege, Hans-Christian A1 - Menzel, Randolf A1 - Rybak, Jürgen T1 - Model-based autosegmentation of brain structures in the honeybee using statistical shape models T2 - Proc. 8th Int. Congr. of Neuroethology (ICN) Y1 - 2007 ER - TY - CHAP A1 - Giehl, Michael A1 - Gowin, Wolfgang A1 - Engelke, Klaus A1 - Karolczak, Marek A1 - Hege, Hans-Christian A1 - Schmidt-Ehrenberg, Johannes A1 - Felsenberg, Dieter T1 - Micro-CT zur Darstellung kontrastgebender Strukturen im Weichteilgewebe T2 - 81. Deutscher Röntgenkongress Y1 - 2000 CY - Wiesbaden ER - TY - JOUR A1 - Cournia, Zoe A1 - Allen, Toby W. A1 - Andricioaei, Ioan A1 - Antonny, Bruno A1 - Baum, Daniel A1 - Brannigan, Grace A1 - Buchete, Nicolae-Viorel A1 - Deckman, Jason T. A1 - Delemotte, Lucie A1 - del Val, Coral A1 - Friedman, Ran A1 - Gkeka, Paraskevi A1 - Hege, Hans-Christian A1 - Hénin, Jérôme A1 - Kasimova, Marina A. A1 - Kolocouris, Antonios A1 - Klein, Michael L. A1 - Khalid, Syma A1 - Lemieux, Joanne A1 - Lindow, Norbert A1 - Roy, Mahua A1 - Selent, Jana A1 - Tarek, Mounir A1 - Tofoleanu, Florentina A1 - Vanni, Stefano A1 - Urban, Sinisa A1 - Wales, David J. A1 - Smith, Jeremy C. A1 - Bondar, Ana-Nicoleta T1 - Membrane Protein Structure, Function and Dynamics: A Perspective from Experiments and Theory JF - Journal of Membrane Biology Y1 - 2015 U6 - https://doi.org/10.1007/s00232-015-9802-0 VL - 248 IS - 4 SP - 611 EP - 640 ER - TY - CHAP A1 - Krämer, Martin A1 - Herrmann, Karl-Heinz A1 - Boeth, Heide A1 - Tycowicz, Christoph von A1 - König, Christian A1 - Zachow, Stefan A1 - Ehrig, Rainald A1 - Hege, Hans-Christian A1 - Duda, Georg A1 - Reichenbach, Jürgen T1 - Measuring 3D knee dynamics using center out radial ultra-short echo time trajectories with a low cost experimental setup T2 - ISMRM (International Society for Magnetic Resonance in Medicine), 23rd Annual Meeting 2015, Toronto, Canada Y1 - 2015 ER - TY - JOUR A1 - Günther, Tobias A1 - Kuhn, Alexander A1 - Hege, Hans-Christian A1 - Theisel, Holger T1 - MCFTLE: Monte Carlo Rendering of Finite-Time Lyapunov Exponent Fields JF - Computer Graphics Forum Y1 - 2016 U6 - https://doi.org/10.1111/cgf.12914 N1 - By mistake the fourth author Hans-Christian Hege has been ommitted in the journal publication VL - 35 IS - 3 SP - 381 EP - 390 ER - TY - GEN A1 - Günther, Tobias A1 - Kuhn, Alexander A1 - Hege, Hans-Christian A1 - Theisel, Holger T1 - MCFTLE: Monte Carlo Rendering of Finite-Time Lyapunov Exponent Fields N2 - Traditionally, Lagrangian fields such as finite-time Lyapunov exponents (FTLE) are precomputed on a discrete grid and are ray casted afterwards. This, however, introduces both grid discretization errors and sampling errors during ray marching. In this work, we apply a progressive, view-dependent Monte Carlo-based approach for the visualization of such Lagrangian fields in time-dependent flows. Our ap- proach avoids grid discretization and ray marching errors completely, is consistent, and has a low memory consumption. The system provides noisy previews that con- verge over time to an accurate high-quality visualization. Compared to traditional approaches, the proposed system avoids explicitly predefined fieldline seeding structures, and uses a Monte Carlo sampling strategy named Woodcock tracking to distribute samples along the view ray. An acceleration of this sampling strategy requires local upper bounds for the FTLE values, which we progressively acquire during the rendering. Our approach is tailored for high-quality visualizations of complex FTLE fields and is guaranteed to faithfully represent detailed ridge surface structures as indicators for Lagrangian coherent structures (LCS). We demonstrate the effectiveness of our approach by using a set of analytic test cases and real-world numerical simulations. T3 - ZIB-Report - 16-21 KW - Picture/Image Generation, Display algorithms, Three-Dimensional Graphics and Realism, Raytracing Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-59054 SN - 1438-0064 N1 - By mistake the fourth author Hans-Christian Hege has been ommitted in the journal publication ER - TY - JOUR A1 - Zachow, Stefan A1 - Hege, Hans-Christian A1 - Deuflhard, Peter T1 - Maxillofacial surgery planning with 3D soft tissue prediction - modeling, planning, simulation JF - 2. Int. Conf. on Advanced Digital Technology in Head and Neck Reconstruction, Abstract 33 Y1 - 2005 SP - 64 CY - Banff, Alberta, CA ER - TY - GEN A1 - Hege, Hans-Christian A1 - Polthier, Konrad A1 - Rumpf, Martin T1 - MathInsight 2002 Y1 - 2001 ER - TY - BOOK A1 - Hege, Hans-Christian A1 - (Eds.), Konrad T1 - Mathematical Visualization - Algorithms, Applications, and Numerics Y1 - 1998 SN - ISBN 3-540-63991-8 PB - Springer CY - Heidelberg ER - TY - CHAP A1 - Olbrich, Stephan A1 - Weinkauf, Tino A1 - Merzky, André A1 - Knipp, Harald A1 - Hege, Hans-Christian A1 - Pralle, Helmut ED - Knop, J. von T1 - Lösungsansätze zur Visualisierung im High Performance Computing und Networking Kontext T2 - Zukunft der Netze - Die Verletzbarkeit meistern. Y1 - 2002 SP - 269 EP - 279 CY - Düsseldorf, Germany ER - TY - CHAP A1 - Kasten, Jens A1 - Petz, Christoph A1 - Hotz, Ingrid A1 - Noack, Bernd R. A1 - Hege, Hans-Christian ED - Magnor, Marcus ED - Rosenhahn, Bodo ED - Theisel, Holger T1 - Localized Finite-time Lyapunov Exponent for Unsteady Flow Analysis T2 - Vision Modeling and Visualization Y1 - 2009 SN - 978-3-9804874-8-1 VL - 1 SP - 265 EP - 274 PB - Universität Magdeburg, Inst. f. Simulation u. Graph. ER - TY - GEN A1 - Dercksen, Vincent J. A1 - Oberlaender, Marcel A1 - Sakmann, Bert A1 - Hege, Hans-Christian T1 - Light Microscopy-Based Reconstruction and Interactive Structural Analysis of Cortical Neural Networks T2 - BioVis 2011 Abstracts, 1st IEEE Symposium on Biological Data Visualization Y1 - 2011 ER - TY - JOUR A1 - Lindow, Norbert A1 - Baum, Daniel A1 - Hege, Hans-Christian T1 - Ligand Excluded Surface: A New Type of Molecular Surface JF - IEEE Transactions on Visualization and Computer Graphics N2 - The most popular molecular surface in molecular visualization is the solvent excluded surface (SES). It provides information about the accessibility of a biomolecule for a solvent molecule that is geometrically approximated by a sphere. During a period of almost four decades, the SES has served for many purposes – including visualization, analysis of molecular interactions and the study of cavities in molecular structures. However, if one is interested in the surface that is accessible to a molecule whose shape differs significantly from a sphere, a different concept is necessary. To address this problem, we generalize the definition of the SES by replacing the probe sphere with the full geometry of the ligand defined by the arrangement of its van der Waals spheres. We call the new surface ligand excluded surface (LES) and present an efficient, grid-based algorithm for its computation. Furthermore, we show that this algorithm can also be used to compute molecular cavities that could host the ligand molecule. We provide a detailed description of its implementation on CPU and GPU. Furthermore, we present a performance and convergence analysis and compare the LES for several molecules, using as ligands either water or small organic molecules. Y1 - 2014 U6 - https://doi.org/10.1109/TVCG.2014.2346404 VL - 20 IS - 12 SP - 2486 EP - 2495 ER - TY - GEN A1 - Lindow, Norbert A1 - Baum, Daniel A1 - Hege, Hans-Christian T1 - Ligand Excluded Surface: A New Type of Molecular Surface N2 - The most popular molecular surface in molecular visualization is the solvent excluded surface (SES). It provides information about the accessibility of a biomolecule for a solvent molecule that is geometrically approximated by a sphere. During a period of almost four decades, the SES has served for many purposes – including visualization, analysis of molecular interactions and the study of cavities in molecular structures. However, if one is interested in the surface that is accessible to a molecule whose shape differs significantly from a sphere, a different concept is necessary. To address this problem, we generalize the definition of the SES by replacing the probe sphere with the full geometry of the ligand defined by the arrangement of its van der Waals spheres. We call the new surface ligand excluded surface (LES) and present an efficient, grid-based algorithm for its computation. Furthermore, we show that this algorithm can also be used to compute molecular cavities that could host the ligand molecule. We provide a detailed description of its implementation on CPU and GPU. Furthermore, we present a performance and convergence analysis and compare the LES for several molecules, using as ligands either water or small organic molecules. T3 - ZIB-Report - 14-27 Y1 - 2014 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-51194 SN - 1438-0064 ER - TY - CHAP A1 - Hege, Hans-Christian A1 - Stalling, Detlev T1 - LIC: Acceleration, Animation, Zoom T2 - Texture Synthesis with Line Integral Convolution, Siggraph 97, 24. Int. Conf. Computer Graphics and Interactive Techniques Y1 - 1997 SP - 17 EP - 49 CY - Los Angeles ER - TY - CHAP A1 - Stalling, Detlev A1 - Hege, Hans-Christian T1 - LIC on Surfaces T2 - Texture Synthesis with Line Integral Convolution, Siggraph 97, 24. Int. Conf. Computer Graphics and Interactive Techniques Y1 - 1997 SP - 51 EP - 64 CY - Los Angeles ER - TY - JOUR A1 - Werner, Armin A1 - Deussen, Oliver A1 - Döllner, Jürgen A1 - Hege, Hans-Christian A1 - Paar, Philip A1 - Rekittke, Jörg ED - Buhmann, Erich ED - Paar, Philip ED - Bishop, Ian ED - Lange, Eckart T1 - Lenné 3D walking through landscape plan JF - Trends in Real-Time Landscape Visualization and Participation Y1 - 2005 SP - 48 EP - 59 PB - Wichmann Verlag ER - TY - JOUR A1 - Heinze, Rieke A1 - Dipankar, Anurag A1 - Henken, Cintia Carbajal A1 - Moseley, Christopher A1 - Sourdeval, Odran A1 - Trömel, Silke A1 - Xie, Xinxin A1 - Adamidis, Panos A1 - Ament, Felix A1 - Baars, Holger A1 - Barthlott, Christian A1 - Behrendt, Andreas A1 - Blahak, Ulrich A1 - Bley, Sebastian A1 - Brdar, Slavko A1 - Brueck, Matthias A1 - Crewell, Susanne A1 - Deneke, Hartwig A1 - Di Girolamo, Paolo A1 - Evaristo, Raquel A1 - Fischer, Jürgen A1 - Frank, Christopher A1 - Friederichs, Petra A1 - Göcke, Tobias A1 - Gorges, Ksenia A1 - Hande, Luke A1 - Hanke, Moritz A1 - Hansen, Akio A1 - Hege, Hans-Christian A1 - Hose, Corinna A1 - Jahns, Thomas A1 - Kalthoff, Norbert A1 - Klocke, Daniel A1 - Kneifel, Stefan A1 - Knippertz, Peter A1 - Kuhn, Alexander A1 - van Laar, Thriza A1 - Macke, Andreas A1 - Maurer, Vera A1 - Mayer, Bernhard A1 - Meyer, Catrin I. A1 - Muppa, Shravan K. A1 - Neggers, Roeland A. J. A1 - Orlandi, Emiliano A1 - Pantillon, Florian A1 - Pospichal, Bernhard A1 - Röber, Niklas A1 - Scheck, Leonhard A1 - Seifert, Axel A1 - Seifert, Patric A1 - Senf, Fabian A1 - Siligam, Pavan A1 - Simmer, Clemens A1 - Steinke, Sandra A1 - Stevens, Bjorn A1 - Wapler, Kathrin A1 - Weniger, Michael A1 - Wulfmeyer, Volker A1 - Zängl, Günther A1 - Zhang, Dan A1 - Quaas, Johannes T1 - Large-eddy simulations over Germany using ICON: a comprehensive evaluation JF - Quarterly Journal of the Royal Meteorological Society N2 - Large-eddy simulations (LES) with the new ICOsahedral Non-hydrostatic atmosphere model (ICON) covering Germany are evaluated for four days in spring 2013 using observational data from various sources. Reference simulations with the established Consortium for Small-scale Modelling (COSMO) numerical weather prediction model and further standard LES codes are performed and used as a reference. This comprehensive evaluation approach covers multiple parameters and scales, focusing on boundary-layer variables, clouds and precipitation. The evaluation points to the need to work on parametrizations influencing the surface energy balance, and possibly on ice cloud microphysics. The central purpose for the development and application of ICON in the LES configuration is the use of simulation results to improve the understanding of moist processes, as well as their parametrization in climate models. The evaluation thus aims at building confidence in the model's ability to simulate small- to mesoscale variability in turbulence, clouds and precipitation. The results are encouraging: the high-resolution model matches the observed variability much better at small- to mesoscales than the coarser resolved reference model. In its highest grid resolution, the simulated turbulence profiles are realistic and column water vapour matches the observed temporal variability at short time-scales. Despite being somewhat too large and too frequent, small cumulus clouds are well represented in comparison with satellite data, as is the shape of the cloud size spectrum. Variability of cloud water matches the satellite observations much better in ICON than in the reference model. In this sense, it is concluded that the model is fit for the purpose of using its output for parametrization development, despite the potential to improve further some important aspects of processes that are also parametrized in the high-resolution model. Y1 - 2017 U6 - https://doi.org/10.1002/qj.2947 VL - 143 IS - 702 SP - 69 EP - 100 ER - TY - JOUR A1 - Kasten, Jens A1 - Petz, Christoph A1 - Hotz, Ingrid A1 - Hege, Hans-Christian A1 - Noack, Bernd A1 - Tadmor, Gilead T1 - Lagrangian Feature Extraction of the Cylinder Wake JF - Physics of Fluids Y1 - 2010 U6 - https://doi.org/10.1063/1.3483220 VL - 22 IS - 9 SP - 091108 ER - TY - CHAP A1 - Kuß, Anja A1 - Hege, Hans-Christian T1 - Knowledge Representation for Digital Atlases T2 - Conference Abstracts: Workshop of the Working Group 'Ontologies in Biomedicine and the Life Science' Y1 - 2009 PB - Max-Planck Institute for Evolutionary Anthropology CY - Leipzig ER - TY - JOUR A1 - Hanik, Martin A1 - Ducke, Benjamin A1 - Hege, Hans-Christian A1 - Fless, Friederike A1 - von Tycowicz, Christoph T1 - Intrinsic shape analysis in archaeology: A case study on ancient sundials JF - Journal on Computing and Cultural Heritage N2 - The fact that the physical shapes of man-made objects are subject to overlapping influences—such as technological, economic, geographic, and stylistic progressions—holds great information potential. On the other hand, it is also a major analytical challenge to uncover these overlapping trends and to disentagle them in an unbiased way. This paper explores a novel mathematical approach to extract archaeological insights from ensembles of similar artifact shapes. We show that by considering all shape information in a find collection, it is possible to identify shape patterns that would be difficult to discern by considering the artifacts individually or by classifying shapes into predefined archaeological types and analyzing the associated distinguishing characteristics. Recently, series of high-resolution digital representations of artifacts have become available. Such data sets enable the application of extremely sensitive and flexible methods of shape analysis. We explore this potential on a set of 3D models of ancient Greek and Roman sundials, with the aim of providing alternatives to the traditional archaeological method of “trend extraction by ordination” (typology). In the proposed approach, each 3D shape is represented as a point in a shape space—a high-dimensional, curved, non-Euclidean space. Proper consideration of its mathematical properties reduces bias in data analysis and thus improves analytical power. By performing regression in shape space, we find that for Roman sundials, the bend of the shadow-receiving surface of the sundials changes with the latitude of the location. This suggests that, apart from the inscribed hour lines, also a sundial’s shape was adjusted to the place of installation. As an example of more advanced inference, we use the identified trend to infer the latitude at which a sundial, whose location of installation is unknown, was placed. We also derive a novel method for differentiated morphological trend assertion, building upon and extending the theory of geometric statistics and shape analysis. Specifically, we present a regression-based method for statistical normalization of shapes that serves as a means of disentangling parameter-dependent effects (trends) and unexplained variability. In addition, we show that this approach is robust to noise in the digital reconstructions of the artifact shapes. Y1 - 2023 U6 - https://doi.org/10.1145/3606698 VL - 16 IS - 4 SP - 1 EP - 26 ER - TY - JOUR A1 - Kähler, Ralf A1 - Simon, Mark A1 - Hege, Hans-Christian T1 - Interactive Volume Rendering of Large Data Sets Using Adaptive Mesh Refinement Hierarchies JF - IEEE Transactions on Visualization and Computer Graphics Y1 - 2003 U6 - https://doi.org/10.1109/TVCG.2003.1207442 VL - 9 IS - 3 SP - 341 EP - 351 ER - TY - GEN A1 - Dercksen, Vincent J. A1 - Oberlaender, Marcel A1 - Sakmann, Bert A1 - Hege, Hans-Christian ED - Linsen, Lars ED - Hagen, Hans ED - Hamann, Bernd ED - Hege, Hans-Christian T1 - Interactive Visualization – a Key Prerequisite for Reconstruction of Anatomically Realistic Neural Networks T2 - Visualization in Medicine and Life Sciences II Y1 - 2012 UR - http://www.zib.de/visual/publications/sources/src-2012/DercksenVMLS2012web.pdf SP - 27 EP - 44 PB - Springer, Berlin ER - TY - CHAP A1 - Prohaska, Steffen A1 - Hege, Hans-Christian A1 - Giehl, Michael A1 - Gowin, Wolfgang T1 - Interactive Visualization to Support Quantification of Bone Biopsies T2 - 2nd European Congress ’Achievements in Space Medicine into Health Care Practice and Industry’ Y1 - 2003 CY - Berlin-Adlershof ER - TY - GEN A1 - Lindow, Norbert A1 - Baum, Daniel A1 - Leborgne, Morgan A1 - Hege, Hans-Christian T1 - Interactive Visualization of RNA and DNA Structures N2 - The analysis and visualization of nucleic acids (RNA and DNA) play an increasingly important role due to the growing number of known 3-dimensional structures of such molecules. The great complexity of these structures, in particular, those of RNA, demands interactive visualization to get deeper insights into the relationship between the 2D secondary structure motifs and their 3D tertiary structures. Over the last decades, a lot of research in molecular visualization has focused on the visual exploration of protein structures while nucleic acids have only been marginally addressed. In contrast to proteins, which are composed of amino acids, the ingredients of nucleic acids are nucleotides. They form structuring patterns that differ from those of proteins and, hence, also require different visualization and exploration techniques. In order to support interactive exploration of nucleic acids, the computation of secondary structure motifs as well as their visualization in 2D and 3D must be fast. Therefore, in this paper, we focus on the performance of both the computation and visualization of nucleic acid structure. For the first time, we present a ray casting-based visualization of RNA and DNA secondary and tertiary structures, which enables real-time visualization of even large molecular dynamics trajectories. Furthermore, we provide a detailed description of all important aspects to visualize nucleic acid secondary and tertiary structures. With this, we close an important gap in molecular visualization. T3 - ZIB-Report - 18-33 KW - ribonucleic acids KW - DNA KW - RNA KW - secondary & tertiary structures KW - interactive rendering KW - ray casting KW - brushing & linking Y1 - 2018 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-69704 SN - 1438-0064 ER - TY - JOUR A1 - Lindow, Norbert A1 - Baum, Daniel A1 - Leborgne, Morgan A1 - Hege, Hans-Christian T1 - Interactive Visualization of RNA and DNA Structures JF - IEEE Transactions on Visualization and Computer Graphics N2 - The analysis and visualization of nucleic acids (RNA and DNA) is playing an increasingly important role due to their fundamental importance for all forms of life and the growing number of known 3D structures of such molecules. The great complexity of these structures, in particular, those of RNA, demands interactive visualization to get deeper insights into the relationship between the 2D secondary structure motifs and their 3D tertiary structures. Over the last decades, a lot of research in molecular visualization has focused on the visual exploration of protein structures while nucleic acids have only been marginally addressed. In contrast to proteins, which are composed of amino acids, the ingredients of nucleic acids are nucleotides. They form structuring patterns that differ from those of proteins and, hence, also require different visualization and exploration techniques. In order to support interactive exploration of nucleic acids, the computation of secondary structure motifs as well as their visualization in 2D and 3D must be fast. Therefore, in this paper, we focus on the performance of both the computation and visualization of nucleic acid structure. We present a ray casting-based visualization of RNA and DNA secondary and tertiary structures, which enables for the first time real-time visualization of even large molecular dynamics trajectories. Furthermore, we provide a detailed description of all important aspects to visualize nucleic acid secondary and tertiary structures. With this, we close an important gap in molecular visualization. Y1 - 2019 U6 - https://doi.org/10.1109/TVCG.2018.2864507 VL - 25 IS - 1 SP - 967 EP - 976 ER - TY - CHAP A1 - Zöckler, Malte A1 - Stalling, Detlev A1 - Hege, Hans-Christian T1 - Interactive Visualization of 3D-Vector Fields Using Illuminated Streamlines T2 - Proc. IEEE Visualization 1996 Y1 - 1996 U6 - https://doi.org/10.1109/VISUAL.1996.567777 SP - 107 EP - 113 CY - San Fransisco ER - TY - JOUR A1 - Lindow, Norbert A1 - Baum, Daniel A1 - Hege, Hans-Christian T1 - Interactive Rendering of Materials and Biological Structures on Atomic and Nanoscopic Scale JF - Computer Graphics Forum Y1 - 2012 U6 - https://doi.org/10.1111/j.1467-8659.2012.03128.x target VL - 31 IS - 3 SP - 1325 EP - 1334 ER - TY - CHAP A1 - Prohaska, Steffen A1 - Hutanu, Andrei A1 - Kähler, Ralf A1 - Hege, Hans-Christian T1 - Interactive exploration of large remote micro-CT scans T2 - Proc. IEEE Visualization 2004 Y1 - 2004 U6 - https://doi.org/10.1109/VIS.2004.51 SP - 345 EP - 352 CY - Austin, Texas ER - TY - CHAP A1 - Stalling, Detlev A1 - Hege, Hans-Christian T1 - Intelligent Scissors for Medical Image Segmentation T2 - Tagungsband zum 4. Freiburger Workshop Digitale Bildverarbeitung in der Medizin Y1 - 1996 SP - 32 EP - 36 CY - Freiburg ER - TY - JOUR A1 - Wust, Peter A1 - Nadobny, Jacek A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Gellermann, Johanna A1 - Hege, Hans-Christian A1 - Deuflhard, Peter T1 - Influence of Patient Models and Numerical Methods on Predicted Power Deposition Patterns JF - Int. Journal Hyperthermia Y1 - 1999 VL - 15 IS - 6 SP - 519 EP - 540 ER - TY - CHAP A1 - Heller, Markus O. A1 - Wurl, Alexander A1 - Perka, Carsten A1 - Hege, Hans-Christian T1 - In vivo gluteus medius volume and shape variations across gender and disease status BT - Proceedings of ESB2012 - 18th Congress of the European Society of Biomechanics, Lisbon, Portugal, 1–4 July 2012 T2 - Journal of Biomechanics Y1 - 2012 U6 - https://doi.org/10.1016/S0021-9290(12)70359-7 VL - 45, Suppl. 1 SP - S358 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Thamsen, Bente A1 - Berthe, André A1 - Poethke, Jens A1 - Kertzscher, Ulrich A1 - Affeld, Klaus A1 - Petz, Christoph A1 - Hege, Hans-Christian A1 - Hoch, Heinrich A1 - Spuler, Andreas T1 - In Vitro Study of Near-Wall Flow in a Cerebral Aneurysm Model with and without Coils JF - American Journal of Neuroradiology Y1 - 2010 U6 - https://doi.org/10.3174/ajnr.A2121 VL - 31:8 SP - 1521 EP - 1528 ER - TY - JOUR A1 - Goubergrits, Leonid A1 - Spuler, Andreas A1 - Schaller, Jens A1 - Wiegmann, Nils A1 - Berthe, Andre A1 - Hege, Hans-Christian A1 - Affeld, Klaus A1 - Kertzscher, Ulrich T1 - In vitro study of hemodynamic treatment improvement: Hunterian ligation of a fenestrated basilar artery aneurysm after coiling JF - The International Journal of Artificial Organs N2 - Hunterian ligation affecting hemodynamics in vessels was proposed to avoid rebleeding in a case of a fenestrated basilar artery aneurysm after incomplete coil occlusion. We studied the hemodynamics in vitro to predict the hemodynamic changes near the aneurysm remnant caused by Hunterian ligation. A transparent model was fabricated based on three-dimensional rotational angiography imaging. Arteries were segmented and reconstructed. Pulsatile flow in the artery segments near the partially occluded (coiled) aneurysm was investigated by means of particle image velocimetry. The hemodynamic situation was investigated before and after Hunterian ligation of either the left or the right vertebral artery (LVA/RVA). Since post-ligation flow rate in the basilar artery was unknown, reduced and retained flow rates were simulated for both ligation options. Flow in the RVA and in the corresponding fenestra vessel is characterized by a vortex at the vertebrobasilar junction, whereas the LVA exhibits undisturbed laminar flow. Both options (RVA or LVA ligation) cause a significant flow reduction near the aneurysm remnant with a retained flow rate. The impact of RVA ligation is, however, significantly higher. This in vitro case study shows that flow reduction near the aneurysm remnant can be achieved by Hunterian ligation and that this effect depends largely on the selection of the ligated vessel. Thus the ability of the proposed in vitro pipe-line to improve hemodynamic impact of the proposed therapy was successfully proved. Y1 - 2014 U6 - https://doi.org/10.5301/ijao.5000314 VL - 37 IS - 4 SP - 325 EP - 335 ER - TY - CHAP A1 - Kainmüller, Dagmar A1 - Lamecker, Hans A1 - Seim, Heiko A1 - Zachow, Stefan A1 - Hege, Hans-Christian ED - Navab, Tianzi ED - P. W. Pluim, Josien ED - Viergever, Max T1 - Improving Deformable Surface Meshes through Omni-directional Displacements and MRFs T2 - Proc. Medical Image Computing and Computer Assisted Intervention (MICCAI) Y1 - 2010 U6 - https://doi.org/10.1007/978-3-642-15705-9_28 VL - 6361 SP - 227 EP - 234 PB - Springer ER - TY - CHAP A1 - Poethke, Jens A1 - Goubergrits, Leonid A1 - Kertzscher, Ulrich A1 - Spuler, Andreas A1 - Petz, Christoph A1 - Hege, Hans-Christian ED - Jos Vander Sloten, Pascal ED - Haueisen, Jens T1 - Impact of imaging modality for analysis of a cerebral aneurysm: Comparison between CT, MRI and 3DRA T2 - Proceedings of the 4th European Conference of the International Federation for Medical and Biological Engineering Y1 - 2008 U6 - https://doi.org/10.1007/978-3-540-89208-3 SP - 1889 EP - 1893 PB - Springer-Verlag CY - Antwerp, Belgium ER - TY - GEN A1 - Lamecker, Hans A1 - Hege, Hans-Christian A1 - Tabelow, Karsten A1 - Polzehl, Jörg ED - Deuflhard, Peter ED - et al., T1 - Image Processing T2 - MATHEON - Mathematics for Key Technologies Y1 - 2014 U6 - https://doi.org/10.4171/137 SP - 359 EP - 376 PB - European Mathematical Society ER - TY - CHAP A1 - Klindt, Marco A1 - Baum, Daniel A1 - Prohaska, Steffen A1 - Hege, Hans-Christian T1 - iCon.text – a customizable iPad app for kiosk applications in museum exhibitions T2 - EVA 2012 Berlin Y1 - 2012 SP - 150 EP - 155 PB - Gesellschaft zur Förderung angewandter Informatik e.V. CY - Volmerstraße 3, 12489 Berlin ER -