TY - GEN A1 - Deuflhard, Peter A1 - Louis, Alfred A1 - Schlegel, W. A1 - Seebass, Martin T1 - Workshop "Scientific Computing in der Medizin" SCMED '97 N2 - Die Arbeitstagung \glqq Scientific Computing in der Medizin\grqq , kurz SCMED \grq 97, findet vom 22. - 23. September 1997 im neu errichteten Gebäude des Konrad-Zuse-Zentrums auf dem Dahlemer naturwissenschaftlichen Campus der Freien Universtät Berlin statt. T3 - ZIB-Report - TR-97-05 Y1 - 1997 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-5474 ER - TY - CHAP A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Zöckler, Malte A1 - Hege, Hans-Christian A1 - Wust, Peter A1 - Felix, Roland A1 - Deuflhard, Peter T1 - Surface Mesh Generation for Numerical Simulations of Hyperthermia Treatments T2 - Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology (ESHO-97) Y1 - 1997 SP - 146 ER - TY - CHAP A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Zöckler, M. A1 - Hege, Hans-Christian A1 - Wust, Peter A1 - Felix, Roland A1 - Deuflhard, Peter T1 - Surface Mesh Generation for Numerical Simulations of Hyperthermia Treatments T2 - Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997 Y1 - 1997 SP - 146 ER - TY - CHAP A1 - Wust, Peter A1 - Nadobny, Jacek A1 - Gellermann, Johanna A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Felix, Roland T1 - Patient Models and Algorithms for Hyperthermia Planning T2 - Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology ESHO-97 Y1 - 1997 ER - TY - CHAP A1 - Wust, Peter A1 - Nadobny, Johanna A1 - Gellermann, Johanna A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Hege, Hans-Christian A1 - Deuflhard, Peter A1 - Budach, Volker A1 - Felix, Roland T1 - Patient Models and Algorithms for Hyperthermia Planning T2 - Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997 Y1 - 1997 SP - 75 ER - TY - GEN A1 - Erdmann, Bodo A1 - Lang, Jens A1 - Seebass, Martin T1 - Optimization of Temperature Distributions for Regional Hyperthermia Based on a Nonlinear Heat Transfer Model N2 - We describe an optimization process specially designed for regional hyperthermia of deap seated tumors in order to achieve desired steady--state temperature distributions. A nonlinear three--dimensional heat--transfer model based on temperature--dependent blood perfusion is applied to predict the temperature. Optimal heating is obtained by minimizing an integral object function which measures the distance between desired and model predicted temperatures. Sequential minima are calculated from successively improved constant--rate perfusion models employing a damped Newton method in an inner iteration. Numerical results for a Sigma 60 applicator are presented. This work has been supported by Deutsche Forschungsgemeinschaft (DFG) within the Sonderforschungsbereich 273 \glqq Hyperthermie: Methodik und Klinik \grqq . T3 - ZIB-Report - SC-97-59 Y1 - 1997 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-3283 ER - TY - CHAP A1 - Beck, Rudolf A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebass, Martin A1 - Stalling, Detlev ED - Hege, Hans-Christian ED - Polthier, Konrad T1 - Numerical Algorithms and Visualization in Medical Treament Planning T2 - Visualization and Mathematics Y1 - 1997 SP - 303 EP - 328 PB - Springer-Verlag ER - TY - CHAP A1 - Deuflhard, Peter A1 - Seebaß, Martin A1 - Stalling, Detlev A1 - Beck, Rudolf A1 - Hege, Hans-Christian ED - Sydow, Achim T1 - Hyperthermia Treatment Planning in Clinical Therapy T2 - Computational Physics, Chemistry and Biology (Proceedings of the 15th IMACS World Congress 1997 on Scientific Computation 3, Modelling and Applied Mathematics) Y1 - 1997 SP - 9 EP - 17 PB - Wissenschaft und Technik Verlag ER - TY - CHAP A1 - Deuflhard, Peter A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Beck, Rudolf A1 - Hege, Hans-Christian ED - Sydow, Achim T1 - Hyperthermia Treatment Planning in Clinical Cancer Therapy:Modelling, Simulation, and Visualization T2 - Computational Physics, Chemistry and Biology Y1 - 1997 VL - 3 PB - Wissenschaft und Technik Verlag CY - Plenary keynote talk, 15th IMACS World Congress 1997 on Scientific Computation, Modelling and Applied Mathematics ER - TY - GEN A1 - Deuflhard, Peter A1 - Seebass, Martin A1 - Stalling, Detlev A1 - Beck, Rudolf A1 - Hege, Hans-Christian T1 - Hyperthermia Treatment Planning in Clinical Cancer Therapy: Modelling, Simulation and Visualization N2 - \noindent The speaker and his co-workers in Scientific Computing and Visualization have established a close cooperation with medical doctors at the Rudolf--Virchow--Klinikum of the Humboldt University in Berlin on the topic of regional hyperthermia. In order to permit a patient--specific treatment planning, a special software system ({\sf\small HyperPlan}) has been developed. \noindent A mathematical model of the clinical system ({\it radio frequency applicator with 8 antennas, water bolus, individual patient body}) involves Maxwell's equations in inhomogeneous media and a so--called bio--heat transfer PDE describing the temperature distribution in the human body. The electromagnetic field and the thermal phenomena need to be computed at a speed suitable for the clinical environment. An individual geometric patient model is generated as a quite complicated tetrahedral ``coarse'' grid (several thousands of nodes). Both Maxwell's equations and the bio--heat transfer equation are solved on that 3D--grid by means of {\em adaptive} multilevel finite element methods, which automatically refine the grid where necessary in view of the required accuracy. Finally optimal antenna parameters for the applicator are determined . \noindent All steps of the planning process are supported by powerful visualization methods. Medical images, contours, grids, simulated electromagnetic fields and temperature distributions can be displayed in combination. A number of new algorithms and techniques had to be developed and implemented. Special emphasis has been put on advanced 3D interaction methods and user interface issues. T3 - ZIB-Report - SC-97-26 Y1 - 1997 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-2958 ER -