TY - GEN A1 - Beck, Rudolf A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebass, Martin A1 - Stalling, Detlev T1 - Numerical Algorithms and Visualization in Medical Treament Planning N2 - After a short summary on therapy planning and the underlying technologies we discuss quantitative medicine by giving a short overview on medical image data, summarizing some applications of computer based treatment planning, and outlining requirements on medical planning systems. Then we continue with a description of our medical planning system {\sf HyperPlan}. It supports typical working steps in therapy planning, like data aquisition, segmentation, grid generation, numerical simulation and optimization, accompanying these with powerful visualization and interaction techniques. T3 - ZIB-Report - SC-96-54 Y1 - 1996 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-2643 ER - TY - CHAP A1 - Beck, Rudolf A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebass, Martin A1 - Stalling, Detlev ED - Hege, Hans-Christian ED - Polthier, Konrad T1 - Numerical Algorithms and Visualization in Medical Treament Planning T2 - Visualization and Mathematics Y1 - 1997 SP - 303 EP - 328 PB - Springer-Verlag ER - TY - CHAP A1 - Beck, Rudolf A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebaß, Martin A1 - Stalling, Detlev ED - Hege, Hans-Christian ED - Polthier, Konrad T1 - Numerical Algorithms and Visualization in Medical Treatment Planning T2 - Visualization and Mathematics 1997 Y1 - 1996 SP - 303 EP - 328 PB - Springer, Heidelberg ER - TY - CHAP A1 - Beck, Rudolf A1 - Hege, Hans-Christian A1 - Seebass, Martin A1 - Wust, Peter A1 - Deuflhard, Peter A1 - Felix, Roland ED - Franconi, Cafiero T1 - Adaptive finite element codes for numerical calculations in hyperthermia treatment planning T2 - Proc. of the 7th Int. Congress on Hyperthermic Oncology, Rome, Italy, April 1996 Y1 - 1996 VL - 2 SP - 515 EP - 517 ER - TY - CHAP A1 - Beck, Rudolf A1 - Hege, Hans-Christian A1 - Seebaß, Martin A1 - Wust, Peter A1 - Deuflhard, Peter A1 - Felix, Roland T1 - Adaptive Finite Element Codes for Numerical Calculations in Hyperthermia Treatment Planning T2 - Proceedings of the 17th Congress on Hyperthermic Oncology Y1 - 1996 VL - 2 SP - 515 EP - 517 CY - Rome, Italy ER - TY - GEN A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebass, Martin T1 - Progress Towards a Combined MRI/Hyperthermia System N2 - Regional hyperthermia, a clinical cancer therapy, is the main topic of the Sonderforschungsbereich Hyperthermia: Scientific Methods and Clinical Applications'' at Berlin. In recent years, technological improvements towards a better concentration of heat to the desired target region have been achieved. These include a rather sophisticated integrated software environment for therapy planning and a new hyperthermia applicator. In a next step, a detailed closed loop monitoring of the actual treatment is to be developed. For this purpose the hyperthermia applicator is combined with an MRI system, which will allow to check the positioning of the patients and to measure individual blood perfusion as well as the 3D temperature distribution. The measurements will then be employed for an on-line control of the whole treatment. In this intended setting, new fast feedback control algorithms will come into play. T3 - ZIB-Report - 00-07 KW - hyperthermia KW - medical therapy planning KW - applicator design KW - interventional MRI Y1 - 2000 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-5755 ER - TY - CHAP A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebass, Martin ED - Grönemeyer, W. T1 - Progress Towards a Combined MRI Hyperthermia System T2 - Proc. Second Int. Congress HIGH CARE 2000, Bochum Y1 - 2000 ER - TY - CHAP A1 - Deuflhard, Peter A1 - Hege, Hans-Christian A1 - Seebaß, Martin T1 - Progress Towards a Combined MRI/Hyperthermia System T2 - Proceedings Second International Congress HIGH CARE 2000 Y1 - 2000 CY - Bochum ER - TY - GEN A1 - Deuflhard, Peter A1 - Louis, Alfred A1 - Schlegel, W. A1 - Seebass, Martin T1 - Workshop "Scientific Computing in der Medizin" SCMED '97 N2 - Die Arbeitstagung \glqq Scientific Computing in der Medizin\grqq , kurz SCMED \grq 97, findet vom 22. - 23. September 1997 im neu errichteten Gebäude des Konrad-Zuse-Zentrums auf dem Dahlemer naturwissenschaftlichen Campus der Freien Universtät Berlin statt. T3 - ZIB-Report - TR-97-05 Y1 - 1997 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-5474 ER - TY - GEN A1 - Deuflhard, Peter A1 - Seebass, Martin T1 - Adaptive Multilevel FEM as Decisive Tools in the Clinical Cancer Therapy Hyperthermia N2 - The paper surveys recent progress in a joint mathematical-medical project on cancer therapy planning. Within so-called regional hyperthermia the computational task is to tune a set of coupled radiofrequency antennas such that a carefully measured tumor is locally heated, but any outside hot spots are avoided. A mathematical model of the whole clinical system -- air, applicator with antennas, water bolus, individual patient body -- involves Maxwell's equations in inhomogeneous media and a parabolic bioheat transfer equation, which represents a simplified model of heat transfer in the human body (ignoring strong blood vessel heat transport). Both PDEs need to be computed fast and to medical reliability (!) on a workstation within a clinical environment. This requirement triggered a series of new algorithmic developments to be reported here, among which is an adaptive multilevel FEM for Maxwell's equations, which dominates the numerical simulation time. In total, however, the main bulk of computation time (see Table 3 in Section 4 below) still goes into segmentation -- a necessary preprocessing step in the construction a 3D virtual patient from the input of a stack of 2D computed tomograms (left out here). T3 - ZIB-Report - SC-98-30 KW - hyperthermia KW - Maxwell's equations KW - nonlinear heat transfer KW - finite elements Y1 - 1998 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:0297-zib-3739 ER -