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  <doc>
    <id>4189</id>
    <completedYear/>
    <publishedYear>2013</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>reportzib</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2013-07-30</completedDate>
    <publishedDate>2013-07-30</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Fast Generation of Virtual X-ray Images from Deformable Tetrahedral Meshes</title>
    <abstract language="eng">We propose a novel GPU-based approach to render virtual X-ray projections of deformable tetrahedral meshes. These meshes represent the shape and the internal density distribution of a particular anatomical structure and are derived from statistical shape and intensity models (SSIMs). We apply our method to improve the geometric reconstruction of 3D anatomy (e.g.\ pelvic bone) from 2D X-ray images. For that purpose, shape and density of a tetrahedral mesh are varied and virtual X-ray projections are generated within an optimization process until the similarity between the computed virtual X-ray and the respective anatomy depicted in a given clinical X-ray is maximized. The OpenGL implementation presented in this work deforms and projects tetrahedral meshes of high resolution (200.000+ tetrahedra) at interactive rates. It generates virtual X-rays that accurately depict the density distribution of an anatomy of interest. Compared to existing methods that accumulate X-ray attenuation in deformable meshes, our novel approach significantly boosts the deformation/projection performance. The proposed projection algorithm scales better with respect to mesh resolution and complexity of the density distribution, and the combined deformation and projection on the GPU scales better with respect to the number of deformation parameters. The gain in performance allows for a larger number of cycles in the optimization process. Consequently, it reduces the risk of being stuck in a local optimum. We believe that our approach contributes in orthopedic surgery, where 3D anatomy information needs to be extracted from 2D X-rays to support surgeons in better planning joint replacements.</abstract>
    <identifier type="issn">1438-0064</identifier>
    <identifier type="urn">urn:nbn:de:0297-zib-41896</identifier>
    <enrichment key="PeerReviewed">no</enrichment>
    <enrichment key="SourceTitle">appeared in IEEE Transactions on Visualization and Computer Graphics</enrichment>
    <submitter>Moritz Ehlke</submitter>
    <author>Moritz Ehlke</author>
    <author>Heiko Ramm</author>
    <author>Hans Lamecker</author>
    <author>Hans-Christian Hege</author>
    <author>Stefan Zachow</author>
    <series>
      <title>ZIB-Report</title>
      <number>13-38</number>
    </series>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>digitally reconstructed radiographs</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>volume rendering</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>mesh deformation</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>statistical shape and intensity models</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>image registration</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>GPU acceleration</value>
    </subject>
    <collection role="ccs" number="I.">Computing Methodologies</collection>
    <collection role="msc" number="68-XX">COMPUTER SCIENCE (For papers involving machine computations and programs in a specific mathematical area, see Section -04 in that area)</collection>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="visalgo">Visual Data Analysis in Science and Engineering</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="ehlke">Ehlke, Moritz</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="lamecker">Lamecker, Hans</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="projects" number="BSRT-3DFromXray">BSRT-3DFromXray</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <file>https://opus4.kobv.de/opus4-zib/files/4189/Report-13-38.pdf</file>
  </doc>
  <doc>
    <id>3984</id>
    <completedYear>2001</completedYear>
    <publishedYear>2001</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>27</pageFirst>
    <pageLast>35</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>4319</volume>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>San Diego, USA</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Validation of a Linear Elastic Model for Soft Tissue Simulation in Craniofacial Surgery</title>
    <parentTitle language="eng">Proc. SPIE Medical Imaging 2001</parentTitle>
    <identifier type="doi">10.1117/12.428061</identifier>
    <author>Evgeny Gladilin</author>
    <editor>Seong Mun</editor>
    <author>Stefan Zachow</author>
    <author>Peter Deuflhard</author>
    <author>Hans-Christian Hege</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3985</id>
    <completedYear>2001</completedYear>
    <publishedYear>2001</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>Rome, Italy</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">FE-based heuristic approach for the estimation of person-specific facial mimics</title>
    <parentTitle language="eng">Proceedings of Euro-Par 2001: 5-th International Symposium on Computer Methods</parentTitle>
    <enrichment key="Series">Biomechanics and Biomedical Engineering</enrichment>
    <author>Evgeny Gladilin</author>
    <author>Stefan Zachow</author>
    <author>Hans-Christian Hege</author>
    <author>Peter Deuflhard</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3978</id>
    <completedYear>2001</completedYear>
    <publishedYear>2001</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>129</pageFirst>
    <pageLast>134</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>Stuttgart, Germany</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Towards a Realistic Simulation of Individual Facial Mimics</title>
    <parentTitle language="eng">Vision Modeling and Visualization 2001 (VMV)</parentTitle>
    <author>Evgeny Gladilin</author>
    <author>Stefan Zachow</author>
    <author>Hans-Christian Hege</author>
    <author>Peter Deuflhard</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3981</id>
    <completedYear>2001</completedYear>
    <publishedYear>2001</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>137</pageFirst>
    <pageLast>141</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>Hong Kong, China</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Biomechanical Model for Soft Tissue Simulation in Craniofacial Surgery</title>
    <parentTitle language="eng">Medical Imaging and Augmented Reality (MIAR)</parentTitle>
    <identifier type="doi">10.1109/MIAR.2001.930276</identifier>
    <author>Evgeny Gladilin</author>
    <author>Stefan Zachow</author>
    <author>Peter Deuflhard</author>
    <author>Hans-Christian Hege</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3982</id>
    <completedYear>2001</completedYear>
    <publishedYear>2001</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>961</pageFirst>
    <pageLast>964</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>Pula, Croatia</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Virtual Fibers: A Robust Approach for Muscle Simulation</title>
    <parentTitle language="eng">IX Mediterranean Conference on Medical and Biological Engineering and Computing (MEDICON)</parentTitle>
    <author>Evgeny Gladilin</author>
    <author>Stefan Zachow</author>
    <author>Peter Deuflhard</author>
    <author>Hans-Christian Hege</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3983</id>
    <completedYear>2001</completedYear>
    <publishedYear>2001</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>57</pageFirst>
    <pageLast>61</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>Lübeck, Germany</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Validierung eines linear elastischen Modells für die Weichgewebesimulation in der Mund-Kiefer-Gesichtschirurgie</title>
    <parentTitle language="eng">Bildverarbeitung für die Medizin (BVM)</parentTitle>
    <author>Evgeny Gladilin</author>
    <author>Stefan Zachow</author>
    <author>Peter Deuflhard</author>
    <author>Hans-Christian Hege</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3921</id>
    <completedYear>2003</completedYear>
    <publishedYear>2003</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>520</pageFirst>
    <pageLast>527</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>5029</volume>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>San Diego, CA, USA</publisherPlace>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Realistic prediction of individual facial emotion expressions for craniofacial surgery simulations</title>
    <parentTitle language="eng">Proc. SPIE medical Imaging 2003</parentTitle>
    <identifier type="doi">10.1117/12.479584</identifier>
    <author>Evgeny Gladilin</author>
    <editor>Robert Galloway</editor>
    <author>Stefan Zachow</author>
    <author>Peter Deuflhard</author>
    <author>Hans-Christian Hege</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3922</id>
    <completedYear>2003</completedYear>
    <publishedYear>2003</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>343</pageFirst>
    <pageLast>348</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>1256</volume>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">On constitutive modeling of soft tissue for the long-term prediction of cranio-maxillofacial surgery outcome</title>
    <parentTitle language="eng">International Congress Series, CARS2003, Computer Assisted Radiology and Surgery, Proceedings of the 17th International Congress and Exhibition</parentTitle>
    <identifier type="doi">10.1016/S0531-5131(03)00500-4</identifier>
    <author>Evgeny Gladilin</author>
    <author>Stefan Zachow</author>
    <author>Peter Deuflhard</author>
    <author>Hans-Christian Hege</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3904</id>
    <completedYear>2004</completedYear>
    <publishedYear>2004</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>167</pageFirst>
    <pageLast>170</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>42(2)</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Anatomy- and physics-based facial animation for craniofacial surgery simulations</title>
    <parentTitle language="eng">Med Biol Eng Comput.</parentTitle>
    <identifier type="doi">10.1007/BF02344627</identifier>
    <author>Evgeny Gladilin</author>
    <author>Stefan Zachow</author>
    <author>Peter Deuflhard</author>
    <author>Hans-Christian Hege</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>3967</id>
    <completedYear>2002</completedYear>
    <publishedYear>2002</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>3</pageFirst>
    <pageLast>6</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>Springer Verlag</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Towards Patient Specific, Anatomy Based Simulation of Facial Mimics for Surgical Nerve Rehabilitation</title>
    <parentTitle language="eng">Computer Assisted Radiology and Surgery (CARS)</parentTitle>
    <author>Stefan Zachow</author>
    <author>Evgeny Gladilin</author>
    <author>Hans-Christian Hege</author>
    <author>Peter Deuflhard</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="institutes" number="medplan">Therapy Planning</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
</export-example>
