<?xml version="1.0" encoding="utf-8"?>
<export-example>
  <doc>
    <id>10167</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue>Part D</issue>
    <volume>299</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2025-10-17</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Beyond Benchmarks: Towards Robust Artificial Intelligence Bone Segmentation in Socio-Technical Systems</title>
    <abstract language="eng">Despite the advances in automated medical image segmentation, AI models still underperform in various clinical settings, challenging real-world integration. In this multicenter evaluation, we analyzed 20 state-of-the-art mandibular segmentation models across 19,218 segmentations of 1,000 clinically resampled CT/CBCT scans. We show that segmentation accuracy varies by up to 25% depending on socio-technical factors such as voxel size, bone orientation, and patient conditions such as osteosynthesis or pathology. Higher sharpness, isotropic smaller voxels, and neutral orientation significantly improved results, while metallic osteosynthesis and anatomical complexity led to significant degradation. Our findings challenge the common view of AI models as “plug-and-play” tools and suggest evidence-based optimization recommendations for both clinicians and developers. This will in turn boost the integration of AI segmentation tools in routine healthcare.</abstract>
    <parentTitle language="eng">Expert Systems With Applications</parentTitle>
    <identifier type="url">https://www.medrxiv.org/content/10.1101/2025.06.11.25329022v1</identifier>
    <identifier type="doi">10.1016/j.eswa.2025.130031</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Kunpeng Xie</author>
    <submitter>Stefan Zachow</submitter>
    <author>Lennart Johannes Gruber</author>
    <author>Martin Crampen</author>
    <author>Yao Li</author>
    <author>André Ferreira</author>
    <author>Elias Tappeiner</author>
    <author>Maxime Gillot</author>
    <author>Jan Schepers</author>
    <author>Jiangchang Xu</author>
    <author>Tobias Pankert</author>
    <author>Michel Beyer</author>
    <author>Negar Shahamiri</author>
    <author>Reinier ten Brink</author>
    <author>Gauthier Dot</author>
    <author>Charlotte Weschke</author>
    <author>Niels van Nistelrooij</author>
    <author>Pieter-Jan Verhelst</author>
    <author>Yan Guo</author>
    <author>Zhibin Xu</author>
    <author>Jonas Bienzeisler</author>
    <author>Ashkan Rashad</author>
    <author>Tabea Flügge</author>
    <author>Ross Cotton</author>
    <author>Shankeeth Vinayahalingam</author>
    <author>Robert Ilesan</author>
    <author>Stefan Raith</author>
    <author>Dennis Madsen</author>
    <author>Constantin Seibold</author>
    <author>Tong Xi</author>
    <author>Stefaan Bergé</author>
    <author>Sven Nebelung</author>
    <author>Oldřich Kodym</author>
    <author>Osku Sundqvist</author>
    <author>Florian Thieringer</author>
    <author>Hans Lamecker</author>
    <author>Antoine Coppens</author>
    <author>Thomas Potrusil</author>
    <author>Joep Kraeima</author>
    <author>Max Witjes</author>
    <author>Guomin Wu</author>
    <author>Xiaojun Chen</author>
    <author>Adriaan Lambrechts</author>
    <author>Lucia H Soares Cevidanes</author>
    <author>Stefan Zachow</author>
    <author>Alexander Hermans</author>
    <author>Daniel Truhn</author>
    <author>Victor Alves</author>
    <author>Jan Egger</author>
    <author>Rainer Röhrig</author>
    <author>Frank Hölzle</author>
    <author>Behrus Puladi</author>
    <collection role="persons" number="lamecker">Lamecker, Hans</collection>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="projects" number="MODAL-MedLab">MODAL-MedLab</collection>
    <collection role="projects" number="Modal-Seg">Modal-Seg</collection>
    <collection role="projects" number="MODAL-Gesamt">MODAL-Gesamt</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
  <doc>
    <id>10127</id>
    <completedYear>2024</completedYear>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>12/2024</volume>
    <type>article</type>
    <publisherName>Frontiers Media SA</publisherName>
    <publisherPlace/>
    <creatingCorporation>Charité - Universitätsmedizin Berlin</creatingCorporation>
    <contributingCorporation>Zuse Institute Berlin (ZIB)</contributingCorporation>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Impact of the external knee flexion moment on patello-femoral loading derived from in vivo loads and kinematics</title>
    <abstract language="eng">Introduction: Anterior knee pain and other patello-femoral (PF) complications frequently limit the success of total knee arthroplasty as the final treatment of end stage osteoarthritis. However, knowledge about the in-vivo loading conditions at the PF joint remains limited, as no direct measurements are available. We hypothesised that the external knee flexion moment (EFM) is highly predictive of the PF contact forces during activities with substantial flexion of the loaded knee.&#13;
Materials and methods: Six patients (65–80 years, 67–101 kg) with total knee arthroplasty (TKA) performed two activities of daily living: sit-stand-sit and squat. Tibio-femoral (TF) contact forces were measured in vivo using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The relationship between the EFM and the PF contact force was quantified using linear regression.&#13;
Results: Mean peak TF contact forces of 1.97–3.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). The peak EFM ranged from 3.2 to 5.9 %BW times body height, and was a good predictor of the PF contact force (R2 = 0.95 and 0.88 for sit-stand-sit and squat, respectively).&#13;
Discussion: The novel combination of in vivo TF contact forces and internal patellar kinematics enabled a reliable assessment of PF contact forces. The results of the regression analysis suggest that PF forces can be estimated based solely on the EFM from quantitative gait analysis. Our study also demonstrates the relevance of PF contact forces, which reach magnitudes similar to TF forces during activities of daily living.</abstract>
    <parentTitle language="eng">Frontiers in Bioengineering and Biotechnology</parentTitle>
    <identifier type="issn">2296-4185</identifier>
    <identifier type="doi">10.3389/fbioe.2024.1473951</identifier>
    <identifier type="pmid">39881960</identifier>
    <enrichment key="opus_doi_flag">true</enrichment>
    <enrichment key="opus_doi_json">{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T15:51:04Z","timestamp":1753890664327,"version":"3.41.2"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T00:00:00Z","timestamp":1736899200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SFB1444 \/ 427826188 TR 1657\/1-1 DA 1786\/5-1 EH 422-2-1\/MO 3865-1-1"],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Bioeng. Biotechnol."],"abstract":"&lt;jats:sec&gt;&lt;jats:title&gt;Introduction&lt;\/jats:title&gt;&lt;jats:p&gt;Anterior knee pain and other patello-femoral (PF) complications frequently limit the success of total knee arthroplasty as the final treatment of end stage osteoarthritis. However, knowledge about the &lt;jats:italic&gt;in-vivo&lt;\/jats:italic&gt; loading conditions at the PF joint remains limited, as no direct measurements are available. We hypothesised that the external knee flexion moment (EFM) is highly predictive of the PF contact forces during activities with substantial flexion of the loaded knee.&lt;\/jats:p&gt;&lt;\/jats:sec&gt;&lt;jats:sec&gt;&lt;jats:title&gt;Materials and methods&lt;\/jats:title&gt;&lt;jats:p&gt;Six patients (65\u201380\u00a0years, 67\u2013101\u00a0kg) with total knee arthroplasty (TKA) performed two activities of daily living: sit-stand-sit and squat. Tibio-femoral (TF) contact forces were measured &lt;jats:italic&gt;in vivo&lt;\/jats:italic&gt; using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The relationship between the EFM and the PF contact force was quantified using linear regression.&lt;\/jats:p&gt;&lt;\/jats:sec&gt;&lt;jats:sec&gt;&lt;jats:title&gt;Results&lt;\/jats:title&gt;&lt;jats:p&gt;Mean peak TF contact forces of 1.97\u20133.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). The peak EFM ranged from 3.2 to 5.9 %BW times body height, and was a good predictor of the PF contact force (&lt;jats:italic&gt;R&lt;\/jats:italic&gt;&lt;jats:sup&gt;2&lt;\/jats:sup&gt; = 0.95 and 0.88 for sit-stand-sit and squat, respectively).&lt;\/jats:p&gt;&lt;\/jats:sec&gt;&lt;jats:sec&gt;&lt;jats:title&gt;Discussion&lt;\/jats:title&gt;&lt;jats:p&gt;The novel combination of &lt;jats:italic&gt;in vivo&lt;\/jats:italic&gt; TF contact forces and internal patellar kinematics enabled a reliable assessment of PF contact forces. The results of the regression analysis suggest that PF forces can be estimated based solely on the EFM from quantitative gait analysis. Our study also demonstrates the relevance of PF contact forces, which reach magnitudes similar to TF forces during activities of daily living.&lt;\/jats:p&gt;&lt;\/jats:sec&gt;","DOI":"10.3389\/fbioe.2024.1473951","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T06:12:11Z","timestamp":1736921531000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of the external knee flexion moment on patello-femoral loading derived from in vivo loads and kinematics"],"prefix":"10.3389","volume":"12","author":[{"given":"Adam","family":"Trepczynski","sequence":"first","affiliation":[]},{"given":"Paul","family":"Kneifel","sequence":"additional","affiliation":[]},{"given":"Mark","family":"Heyland","sequence":"additional","affiliation":[]},{"given":"Marko","family":"Leskovar","sequence":"additional","affiliation":[]},{"given":"Philippe","family":"Moewis","sequence":"additional","affiliation":[]},{"given":"Philipp","family":"Damm","sequence":"additional","affiliation":[]},{"given":"William R.","family":"Taylor","sequence":"additional","affiliation":[]},{"given":"Stefan","family":"Zachow","sequence":"additional","affiliation":[]},{"given":"Georg N.","family":"Duda","sequence":"additional","affiliation":[]}],"member":"1965","published-online":{"date-parts":[[2025,1,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"104012","DOI":"10.1016\/j.compbiomed.2020.104012","article-title":"Computational frame of ligament in situ strain in a full knee model","volume":"126","author":"Adouni","year":"2020","journal-title":"Comput. Biol. Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1563","DOI":"10.1007\/s10237-019-01159-9","article-title":"A multiscale synthesis: characterizing acute cartilage failure under an aggregate tibiofemoral joint loading","volume":"18","author":"Adouni","year":"2019","journal-title":"Biomech. Model. Mechanobiol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1007\/s00590-019-02499-z","article-title":"Patellar complications following total knee arthroplasty: a review of the current literature","volume":"29","author":"Assiotis","year":"2019","journal-title":"Eur. J. Orthop. Surg. Traumatol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1007\/s11999-009-1046-9","article-title":"Comparing patient outcomes after THA and TKA: is there a difference?","volume":"468","author":"Bourne","year":"2010","journal-title":"Clin. Orthop. Relat. Res."},{"key":"B5","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/j.knee.2004.05.006","article-title":"Patellofemoral forces after total knee arthroplasty: effect of extensor moment arm","volume":"12","author":"Browne","year":"2005","journal-title":"Knee"},{"key":"B6","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1007\/s00167-010-1218-x","article-title":"Three-to six-year follow-up results after high-flexion total knee arthroplasty: can we allow passive deep knee bending?","volume":"19","author":"Cho","year":"2011","journal-title":"Knee Surg. Sports Traumatol. Arthrosc."},{"key":"B7","doi-asserted-by":"publisher","first-page":"2986","DOI":"10.1016\/j.arth.2021.03.053","article-title":"Patellar fracture after total knee arthroplasty with retention: a retrospective analysis of 2954 consecutive cases","volume":"36","author":"Choe","year":"2021","journal-title":"J. Arthroplasty"},{"key":"B8","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1243\/emed_jour_1982_011_019_02","article-title":"Forces during squatting and rising from a deep squat","volume":"11","author":"Dahlkvist","year":"1982","journal-title":"Eng. Med."},{"key":"B9","doi-asserted-by":"publisher","first-page":"85","DOI":"10.2106\/00004623-200300004-00010","article-title":"Impact of patellofemoral design on patellofemoral forces and polyethylene stresses","volume":"85","author":"D'Lima","year":"2003","journal-title":"J. Bone Jt. Surg. Am."},{"key":"B10","doi-asserted-by":"publisher","first-page":"1400","DOI":"10.1016\/j.jbiomech.2010.12.009","article-title":"The SCoRE residual: a quality index to assess the accuracy of joint estimations","volume":"44","author":"Ehrig","year":"2011","journal-title":"J. Biomech."},{"key":"B11","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1007\/s10237-018-01112-2","article-title":"The effect of fibrillar degradation on the mechanics of articular cartilage: a computational model","volume":"18","author":"Faisal","year":"2019","journal-title":"Biomech. Model. Mechanobiol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1302\/0301-620x.89b11.19840","article-title":"High incidence of loosening of the femoral component in legacy posterior stabilised-flex total knee replacement","volume":"89","author":"Han","year":"2007","journal-title":"J. Bone Jt. Surg. Br."},{"key":"B13","doi-asserted-by":"crossref","DOI":"10.1017\/CBO9780511811685","volume-title":"Multiple view geometry in computer vision","author":"Hartley","year":"2004"},{"key":"B14","doi-asserted-by":"publisher","first-page":"1284091","DOI":"10.3389\/fbioe.2023.1284091","article-title":"Lower-limb internal loading and potential consequences for fracture healing","volume":"11","author":"Heyland","year":"2023","journal-title":"Front. Bioeng. Biotechnol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1148\/101.1.101","article-title":"Patella position in the normal knee joint","volume":"101","author":"Insall","year":"1971","journal-title":"Radiology"},{"volume-title":"14243-5: implants for surgery - wear of total knee prostheses - durability performance of the patellofemoral joint","year":"2019","key":"B16"},{"key":"B17","doi-asserted-by":"publisher","first-page":"111549","DOI":"10.1016\/j.jbiomech.2023.111549","article-title":"Patellar tendon elastic properties derived from in vivo loading and kinematics","volume":"151","author":"Kneifel","year":"2023","journal-title":"J. Biomech."},{"key":"B18","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.jbiomech.2004.02.041","article-title":"Knee mechanics: a review of past and present techniques to determine in vivo loads","volume":"38","author":"Komistek","year":"2005","journal-title":"J. Biomech."},{"key":"B19","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1097\/01.blo.0000238803.97713.7d","article-title":"Patella maltracking in posterior-stabilized total knee arthroplasty","volume":"452","author":"Lachiewicz","year":"2006","journal-title":"Clin. Orthop. Relat. Res."},{"key":"B20","doi-asserted-by":"publisher","first-page":"e0185952","DOI":"10.1371\/journal.pone.0185952","article-title":"A moving fluoroscope to capture tibiofemoral kinematics during complete cycles of free level and downhill walking as well as stair descent","volume":"12","author":"List","year":"2017","journal-title":"PLoS One"},{"key":"B21","doi-asserted-by":"publisher","first-page":"2337","DOI":"10.1016\/j.jbiomech.2008.04.039","article-title":"Patellofemoral joint forces","volume":"41","author":"Mason","year":"2008","journal-title":"J. Biomech."},{"key":"B22","doi-asserted-by":"publisher","first-page":"2765","DOI":"10.1007\/s00590-023-03535-9","article-title":"Periprosthetic patella fractures in total knee replacement and revision surgeries: how to diagnose and treat this rare but potentially devastating complication-a review of the current literature","volume":"33","author":"Masoni","year":"2023","journal-title":"Eur. J. Orthop. Surg. Traumatol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.jmbbm.2018.06.035","article-title":"Loading and kinematic profiles for patellofemoral durability testing","volume":"86","author":"Navacchia","year":"2018","journal-title":"J. Mech. Behav. Biomed. Mater"},{"key":"B24","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1097\/01.blo.0000150130.03519.fb","article-title":"Does total knee replacement restore normal knee function?","volume":"431","author":"Noble","year":"2005","journal-title":"Clin. Orthop. Relat. Res."},{"key":"B25","doi-asserted-by":"publisher","first-page":"532","DOI":"10.2106\/00004623-200204000-00004","article-title":"Patellar fracture after total knee arthroplasty","volume":"84","author":"Ortiguera","year":"2002","journal-title":"J. Bone Jt. Surg. Am."},{"key":"B26","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1007\/s00264-013-2081-4","article-title":"Anterior knee pain after total knee arthroplasty: a narrative review","volume":"38","author":"Petersen","year":"2014","journal-title":"Int. Orthop."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1302\/0301-620x.92b8.23794","article-title":"The measurement of patellar height: a review of the methods of imaging","volume":"92","author":"Phillips","year":"2010","journal-title":"J. Bone Jt. Surg. Br."},{"volume-title":"R: a language and environment for statistical computing","year":"2022","key":"B28"},{"key":"B29","doi-asserted-by":"publisher","first-page":"126","DOI":"10.3109\/17453677208991251","article-title":"Experimental analysis of the quadriceps muscle force and patello-femoral joint reaction force for various activities","volume":"43","author":"Reilly","year":"1972","journal-title":"Acta Orthop. Scand."},{"key":"B30","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1016\/s0883-5403(96)80024-6","article-title":"Patellofemoral complications following total knee arthroplasty","volume":"11","author":"Ritter","year":"1996","journal-title":"J. Arthroplasty"},{"key":"B31","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1615\/jlongtermeffmedimplants.2013010099","article-title":"Patellar fractures following total knee arthroplasty: a review","volume":"23","author":"Sayeed","year":"2013","journal-title":"J. Long. Term. Eff. Med. Implants"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1016\/j.arth.2011.01.016","article-title":"Patellofemoral function after total knee arthroplasty: gender-related differences","volume":"26","author":"Sensi","year":"2011","journal-title":"J. Arthroplasty"},{"key":"B33","doi-asserted-by":"publisher","first-page":"642","DOI":"10.1016\/j.jbiomech.2007.09.027","article-title":"In vivo patellofemoral forces in high flexion total knee arthroplasty","volume":"41","author":"Sharma","year":"2008","journal-title":"J. Biomech."},{"key":"B34","doi-asserted-by":"publisher","first-page":"2110","DOI":"10.1177\/03635465231175160","article-title":"Patellofemoral joint loading progression across 35 weightbearing rehabilitation exercises and activities of daily living","volume":"51","author":"Song","year":"2023","journal-title":"Am. J. Sports Med."},{"key":"B35","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/j.gaitpost.2010.05.005","article-title":"Repeatability and reproducibility of OSSCA, a functional approach for assessing the kinematics of the lower limb","volume":"32","author":"Taylor","year":"2010","journal-title":"Gait Posture"},{"key":"B36","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.jbiomech.2017.09.022","article-title":"A comprehensive assessment of the musculoskeletal system: the CAMS-Knee data set","volume":"65","author":"Taylor","year":"2017","journal-title":"J. Biomech."},{"key":"B37","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1002\/jor.21540","article-title":"Patellofemoral joint contact forces during activities with high knee flexion","volume":"30","author":"Trepczynski","year":"2012","journal-title":"J. Orthop. Res."},{"key":"B38","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1038\/s41598-018-37189-z","article-title":"Tibio-femoral contact force distribution is not the only factor governing pivot location after total knee arthroplasty","volume":"9","author":"Trepczynski","year":"2019","journal-title":"Sci. Rep."},{"key":"B39","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1186\/s12984-018-0434-3","article-title":"Impact of antagonistic muscle co-contraction on in vivo knee contact forces","volume":"15","author":"Trepczynski","year":"2018","journal-title":"J. Neuroeng Rehabil."},{"key":"B40","doi-asserted-by":"publisher","first-page":"754715","DOI":"10.3389\/fbioe.2021.754715","article-title":"Dynamic knee joint line orientation is not predictive of tibio-femoral load distribution during walking","volume":"9","author":"Trepczynski","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"B41","doi-asserted-by":"publisher","first-page":"e53281","DOI":"10.7759\/cureus.53281","article-title":"Patella fracture after total knee arthroplasty: a review","volume":"16","author":"Tsivelekas","year":"2024","journal-title":"Cureus"}],"container-title":["Frontiers in Bioengineering and Biotechnology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fbioe.2024.1473951\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T06:12:17Z","timestamp":1736921537000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fbioe.2024.1473951\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,15]]},"references-count":41,"alternative-id":["10.3389\/fbioe.2024.1473951"],"URL":"https:\/\/doi.org\/10.3389\/fbioe.2024.1473951","relation":{},"ISSN":["2296-4185"],"issn-type":[{"type":"electronic","value":"2296-4185"}],"subject":[],"published":{"date-parts":[[2025,1,15]]},"article-number":"1473951"}}</enrichment>
    <enrichment key="opus_crossrefLicence">https://creativecommons.org/licenses/by/4.0/</enrichment>
    <enrichment key="opus_import_origin">crossref</enrichment>
    <enrichment key="opus_doiImportPopulated">PersonAuthorFirstName_1,PersonAuthorLastName_1,PersonAuthorFirstName_2,PersonAuthorLastName_2,PersonAuthorFirstName_3,PersonAuthorLastName_3,PersonAuthorFirstName_4,PersonAuthorLastName_4,PersonAuthorFirstName_5,PersonAuthorLastName_5,PersonAuthorFirstName_6,PersonAuthorLastName_6,PersonAuthorFirstName_7,PersonAuthorLastName_7,PersonAuthorFirstName_8,PersonAuthorLastName_8,PersonAuthorFirstName_9,PersonAuthorLastName_9,PublisherName,TitleMain_1,TitleAbstract_1,TitleParent_1,ArticleNumber,Volume,PublishedYear,IdentifierIssn,Enrichmentopus_crossrefLicence</enrichment>
    <enrichment key="PeerReviewed">yes</enrichment>
    <enrichment key="opus.source">doi-import</enrichment>
    <author>Adam Trepczynski</author>
    <submitter>Stefan Zachow</submitter>
    <author>Paul Kneifel</author>
    <author>Mark Heyland</author>
    <author>Marko Leskovar</author>
    <author>Philippe Moewis</author>
    <author>Philipp Damm</author>
    <author>William R. Taylor</author>
    <author>Stefan Zachow</author>
    <author>Georg N. Duda</author>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="projects" number="DFG_KneeKinematics">DFG_KneeKinematics</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <collection role="projects" number="SFB_1444">SFB_1444</collection>
    <collection role="projects" number="SFB1444">SFB1444</collection>
  </doc>
  <doc>
    <id>10196</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName>The Eurographics Association</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Generalizing Shape-from-Template to Topological Changes</title>
    <abstract language="eng">Reconstructing the surfaces of deformable objects from correspondences between a 3D template and a 2D image is well studied under Shape-from-Template (SfT) methods; however, existing approaches break down when topological changes accompany the deformation. We propose a principled extension of SfT that enables reconstruction in the presence of such changes. Our approach is initialized with a classical SfT solution and iteratively adapts the template by partitioning its spatial domain so as to minimize an energy functional that jointly encodes physical plausibility and reprojection consistency. We demonstrate that the method robustly captures a wide range of practically relevant topological events including tears and cuts on bounded 2D surfaces, thereby establishing the first general framework for topological-change-aware SfT. Experiments on both synthetic and real data confirm that our approach consistently outperforms baseline methods.</abstract>
    <parentTitle language="eng">Smart Tools and Applications in Graphics - Eurographics Italian Chapter Conference</parentTitle>
    <identifier type="arxiv">2511.03459</identifier>
    <identifier type="doi">10.2312/stag.20251322</identifier>
    <identifier type="isbn">978-3-03868-296-7</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="AcceptedDate">28.10.2025</enrichment>
    <author>Kevin Manogue</author>
    <submitter>Agniva Sengupta</submitter>
    <author>Tomasz Schang</author>
    <author>Dilara Kuş</author>
    <author>Jonas Müller</author>
    <author>Stefan Zachow</author>
    <author>Agniva Sengupta</author>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="projects" number="MODAL-MedLab">MODAL-MedLab</collection>
    <collection role="projects" number="MODAL-Gesamt">MODAL-Gesamt</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <collection role="persons" number="sengupta">Sengupta, Agniva</collection>
  </doc>
  <doc>
    <id>10250</id>
    <completedYear>2025</completedYear>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber>27</pageNumber>
    <edition/>
    <issue>12</issue>
    <volume>13</volume>
    <type>article</type>
    <publisherName>MDPI</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2025-12-03</completedDate>
    <publishedDate>2025-12-03</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Computational Insights into Root Canal Treatment: A Survey of Selected Methods in Imaging, Segmentation, Morphological Analysis, and Clinical Management</title>
    <abstract language="eng">Background/Objectives: Root canal treatment (RCT) is a common dental procedure performed to preserve teeth by removing infected or at-risk pulp tissue caused by caries, trauma, or other pulpal conditions. A successful outcome, among others, depends on accurate identification of the root canal anatomy, planning a suitable therapeutic strategy, and ensuring a bacteria-tight root canal filling. Despite advances in dental techniques, there remains limited integration of computational methods to support key stages of treatment. This review aims to provide a comprehensive overview of computational methods applied throughout the full workflow of RCT, examining their potential to support clinical decision-making, improve treatment planning and outcome assessment, and help bridge the interdisciplinary gap between dentistry and computational research. Methods: A comprehensive literature review was conducted to identify and analyze computational methods applied to different stages of RCT, including root canal segmentation, morphological analysis, treatment planning, quality evaluation, follow-up, and prognosis prediction. In addition, a taxonomy based on application was developed to categorize these methods based on their function within the treatment process. Insights from the authors’ own research experience were also incorporated to highlight implementation challenges and practical considerations. Results: The review identified a wide range of computational methods aimed at enhancing the consistency and efficiency of RCT. Key findings include the use of advanced image processing for segmentation, image analysis for diagnosis and treatment planning, machine learning for morphological classification, and predictive modeling for outcome estimation. While some methods demonstrate high sensitivity and specificity in diagnostic and planning tasks, many remain in experimental stages and lack clinical integration. There is also a noticeable absence of advanced computational techniques for micro-computed tomography and morphological analysis. Conclusions: Computational methods offer significant potential to improve decision-making and outcomes in RCT. However, greater focus on clinical translation and development of cross-modality methodology is needed. The proposed taxonomy provides a structured framework for organizing existing methods and identifying future research directions tailored to specific phases of treatment. This review serves as a resource for both dental professionals, computer scientists and researchers seeking to bridge the gap between clinical practice and computational innovation.</abstract>
    <parentTitle language="eng">dentistry journal</parentTitle>
    <identifier type="doi">https://doi.org/10.3390/dj13120579</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <enrichment key="SubmissionStatus">in press</enrichment>
    <enrichment key="AcceptedDate">2025-11-26</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="opus.doi.autoCreate">false</enrichment>
    <enrichment key="opus.urn.autoCreate">true</enrichment>
    <licence>Creative Commons - CC BY - Namensnennung 4.0 International</licence>
    <author>Jianning Li</author>
    <submitter>Jianning Li</submitter>
    <author>Kerstin Bitter</author>
    <author>Anh Duc Nguyen</author>
    <author>Hagay Shemesh</author>
    <author>Paul Zaslansky</author>
    <author>Stefan Zachow</author>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <collection role="persons" number="li">Li, Jianning</collection>
    <collection role="projects" number="InterDent">InterDent</collection>
  </doc>
  <doc>
    <id>9883</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>109574</pageFirst>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>186</volume>
    <type>article</type>
    <publisherName>Elsevier</publisherName>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2024-12-31</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Comparison of Global and Local Optimization Methods for Intensity-based 2D-3D Registration</title>
    <parentTitle language="eng">Computers in Biology and Medicine</parentTitle>
    <identifier type="doi">10.1016/j.compbiomed.2024.109574</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="AcceptedDate">2024-12-11</enrichment>
    <author>Marko Leskovar</author>
    <submitter>Marko Leskovar</submitter>
    <author>Mark Heyland</author>
    <author>Adam Trepczynski</author>
    <author>Stefan Zachow</author>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <collection role="projects" number="SFB_1444">SFB_1444</collection>
    <collection role="projects" number="SFB1444">SFB1444</collection>
  </doc>
  <doc>
    <id>9755</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>1</pageFirst>
    <pageLast>10</pageLast>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2025-09-18</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">MorphoHaptics: An Open-Source Tool for Visuohaptic Exploration of Morphological Image Datasets</title>
    <abstract language="eng">Although digital methods have significantly advanced morphology, practitioners are still challenged to understand and process tomographic data of specimens. As automated processing of fossil data is still insufficient, morphologists still engage in intensive manual work to digitally prepare fossils for research objectives. We present an open-source tool that enables morphologists to explore tomographic data similarly to the physical workflows that traditional fossil preparators experience in the field. Using questionnaires, we assessed the usability of our prototype for virtual fossil preparation and related common tasks in the digital preparation workflow. Our findings indicate that integrating haptics into the virtual preparation workflow enhances the understanding of the morphology and material properties of working specimens and that the visuohaptic sculpting of fossil volumes is straightforward and is an improvement over current digital specimen processing methods.</abstract>
    <parentTitle language="eng">KUI '24: Proceedings of the 21th International Conference on Culture and Computer Science: from Humanism to Digital Humanities</parentTitle>
    <identifier type="arxiv">2409.17766</identifier>
    <identifier type="doi">10.1145/3719236.3719271</identifier>
    <enrichment key="AcceptedDate">2024-09-04</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Lucas Siqueira Rodrigues</author>
    <submitter>Lucas Siqueira Rodrigues</submitter>
    <author>Thomas Kosch</author>
    <author>John Nyakatura</author>
    <author>Stefan Zachow</author>
    <author>Johann Habakuk Israel</author>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <collection role="projects" number="MoA_Cutting">MoA_Cutting</collection>
  </doc>
  <doc>
    <id>10017</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>162</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Shape-from-Template with Generalised Camera</title>
    <abstract language="eng">This article presents a new method for non-rigidly registering a 3D shape to 2D keypoints observed by a constellation of multiple cameras. Non-rigid registration of a 3D shape to observed 2D keypoints, i.e., Shape-from-Template (SfT), has been widely studied using single images, but SfT with information from multiple-cameras jointly opens new directions for extending the scope of known use-cases such as 3D shape registration in medical imaging and registration from hand-held cameras, to name a few. We represent such multi-camera setup with the generalised camera model; therefore any collection of perspective or orthographic cameras observing any deforming object can be registered. We propose multiple approaches for such SfT: the first approach where the corresponded keypoints lie on a direction vector from a known 3D point in space, the second approach where the corresponded keypoints lie on a direction vector from an unknown 3D point in space but with known orientation w.r.t some local reference frame, and a third approach where, apart from correspondences, the silhouette of the imaged object is also known. Together, these form the first set of solutions to the SfT problem with generalised cameras. The key idea behind SfT with generalised camera is the improved reconstruction accuracy from estimating deformed shape while utilising the additional information from the mutual constraints between multiple views of a deformed object. The correspondence-based approaches are solved with convex programming while the silhouette-based approach is an iterative refinement of the results from the convex solutions. We demonstrate the accuracy of our proposed methods on many synthetic and real data.</abstract>
    <parentTitle language="eng">Image and Vision Computing</parentTitle>
    <identifier type="doi">10.1016/j.imavis.2025.105579</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <enrichment key="AcceptedDate">2025-05-06</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <author>Agniva Sengupta</author>
    <submitter>Agniva Sengupta</submitter>
    <author>Stefan Zachow</author>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="projects" number="MODAL-MedLab">MODAL-MedLab</collection>
    <collection role="projects" number="MODAL-Gesamt">MODAL-Gesamt</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <collection role="persons" number="sengupta">Sengupta, Agniva</collection>
  </doc>
  <doc>
    <id>10053</id>
    <completedYear/>
    <publishedYear>2025</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>557</pageFirst>
    <pageLast>563</pageLast>
    <pageNumber/>
    <edition/>
    <issue>10</issue>
    <volume>39</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Interobserver Reliability of the Modified Radiographic Union Score (mRUST) for Tibial and Femoral Fractures</title>
    <abstract language="eng">OBJECTIVES: &#13;
&#13;
To evaluate the reliability of the modified Radiographic Union Score for Tibial fractures (mRUST) as a reliable tool for monitoring lower limb fractures (femur, tibia) treated with various modalities (nail, plate).&#13;
&#13;
METHODS: &#13;
Design: &#13;
Retrospective analysis.&#13;
&#13;
Setting: &#13;
Single center academic hospital in Germany.&#13;
&#13;
Patient Selection Criteria: &#13;
Adult patients (≥18 years) with extra-articular long bone fractures of the lower extremities treated surgically between January 2005 and April 2022, requiring radiographs in two perpendicular planes and at least one follow-up visit, were included. Exclusion criteria were critical clinical conditions, inability to consent, joint articulation fractures, inadequate documentation, or insufficient imaging quality.&#13;
Outcome Measures and Comparisons: &#13;
&#13;
Six international investigators (five orthopedic surgeons, one radiologist) independently assessed fracture line and callus growth per cortex (mRUST) at individualized follow-up time points based on clinical practice. To evaluate interrater reliability, intraclass correlation coefficients were calculated for the overall dataset, and for subsets of rated images, that were defined based on anatomical location (femur/tibia), treatment type (plate/nail fixation), and treatment combinations across locations.&#13;
&#13;
RESULTS: &#13;
A total of 166 patients (63 femur fractures, 103 tibia fractures; 32.5% female, mean age 43.4 (18–84)) with 1136 follow-up time points were analyzed. Overall interrater reliability for mRUST was good (intraclass correlation coefficient 0.77), consistent across fixation methods (nail/plate fixation, 0.79) and anatomical locations (tibia, 0.78; femur, 0.81). Cortex-specific reliability varied, with highest agreement for the medial cortex (0.70–0.74) and lowest for the posterior cortex (0.65–0.74).&#13;
&#13;
CONCLUSIONS: &#13;
The mRUST (radiographic score) demonstrated reliability for monitoring fracture healing in the femur and tibia, irrespective of fixation method, supporting its use as a generalizable tool across lower limb fractures.&#13;
&#13;
LEVEL OF EVIDENCE: &#13;
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.</abstract>
    <parentTitle language="eng">Journal of Orthopaedic Trauma</parentTitle>
    <identifier type="doi">10.1097/BOT.0000000000003032</identifier>
    <identifier type="issn">0890-5339</identifier>
    <enrichment key="opus_doi_flag">true</enrichment>
    <enrichment key="opus_doi_json">{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T22:40:02Z","timestamp":1750891202761,"version":"3.41.0"},"reference-count":0,"publisher":"Ovid Technologies (Wolters Kluwer Health)","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6,24]]},"abstract":"&lt;jats:sec&gt;\n            &lt;jats:title&gt;OBJECTIVES:&lt;\/jats:title&gt;\n            &lt;jats:p&gt;To evaluate the reliability of the modified Radiographic Union Score for Tibial fractures (mRUST) as a reliable tool for monitoring lower limb fractures (Femur, Tibia) treated with various modalities (Nail, Plate).&lt;\/jats:p&gt;\n          &lt;\/jats:sec&gt;\n          &lt;jats:sec&gt;\n            &lt;jats:title&gt;METHODS:&lt;\/jats:title&gt;\n            &lt;jats:p&gt;\n                                 &lt;jats:italic toggle=\"yes\"&gt;Design&lt;\/jats:italic&gt;: Retrospective analysis.&lt;\/jats:p&gt;\n          &lt;\/jats:sec&gt;\n          &lt;jats:sec&gt;\n            &lt;jats:title&gt;Setting:&lt;\/jats:title&gt;\n            &lt;jats:p&gt;Single center academic hospital in Germany.&lt;\/jats:p&gt;\n          &lt;\/jats:sec&gt;\n          &lt;jats:sec&gt;\n            &lt;jats:title&gt;Patient Selection Criteria:&lt;\/jats:title&gt;\n            &lt;jats:p&gt;Adult patients (\u226518 years) with extra-articular long bone fractures of the lower extremities treated surgically between January 2005 and April 2022, requiring radiographs in two perpendicular planes and at least one follow-up visit, were included. Exclusion criteria were critical clinical conditions, inability to consent, joint articulation fractures, inadequate documentation, or insufficient imaging quality.&lt;\/jats:p&gt;\n          &lt;\/jats:sec&gt;\n          &lt;jats:sec&gt;\n            &lt;jats:title&gt;Outcome Measures and Comparisons:&lt;\/jats:title&gt;\n            &lt;jats:p&gt;Six international investigators (five orthopedic surgeons, one radiologist) independently assessed fracture line and callus growth per cortex (mRUST) at individualized follow-up timepoints based on clinical practice. To evaluate inter-rater reliability, intraclass correlation coefficients (ICC) were calculated for the overall dataset, and for subsets of rated images, that were defined based on anatomical location (femur\/tibia), treatment type (plate\/nail fixation), and treatment combinations across locations.&lt;\/jats:p&gt;\n          &lt;\/jats:sec&gt;\n          &lt;jats:sec&gt;\n            &lt;jats:title&gt;RESULTS:&lt;\/jats:title&gt;\n            &lt;jats:p&gt;A total of 166 patients (63 femur fractures, 103 tibia fractures; 32.5% female, mean age 43.4 (18-84)) with 1,136 follow-up timepoints were analyzed. Overall inter-rater reliability for mRUST was good (ICC 0.77), consistent across fixation methods (nail\/plate fixation, 0.79) and anatomical locations (tibia, 0.78; femur, 0.81). Cortex-specific reliability varied, with highest agreement for the medial cortex (0.70\u20130.74) and lowest for the posterior cortex (0.65\u20130.74).&lt;\/jats:p&gt;\n          &lt;\/jats:sec&gt;\n          &lt;jats:sec&gt;\n            &lt;jats:title&gt;CONCLUSIONS:&lt;\/jats:title&gt;\n            &lt;jats:p&gt;The mRUST (radiographic score) demonstrated reliability for monitoring fracture healing in the femur and tibia, irrespective of fixation method, supporting its use as a generalizable tool across lower limb fractures.&lt;\/jats:p&gt;\n          &lt;\/jats:sec&gt;\n          &lt;jats:sec&gt;\n            &lt;jats:title&gt;LEVEL OF EVIDENCE:&lt;\/jats:title&gt;\n            &lt;jats:p&gt;I.&lt;\/jats:p&gt;\n          &lt;\/jats:sec&gt;","DOI":"10.1097\/bot.0000000000003032","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T22:00:09Z","timestamp":1750888809000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Interobserver Reliability of the Modified Radiographic Union Score (mRUST) for Tibial and Femoral Fractures"],"prefix":"10.1097","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4534-0466","authenticated-orcid":false,"given":"Dominik","family":"Deppe","sequence":"first","affiliation":[{"name":"Julius Wolff Institute, Berlin Institute of Health at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"},{"name":"Department of Radiology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin, Berlin, Germany"}]},{"given":"Matteo","family":"Gabriele","sequence":"additional","affiliation":[{"name":"Julius Wolff Institute, Berlin Institute of Health at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"},{"name":"Department of Electrical, Electronic, and Information Engineering - \u201cGuglielmo Marconi\u201d - \u201cDEI\u201d, Alma Mater Studiorum - Universit\u00e0 di Bologna, Cesena, Italy"}]},{"given":"Manuel Giovanni","family":"Mazzoleni","sequence":"additional","affiliation":[{"name":"Hip Department (CAD) Gaetano Pini - CTO Orthopedic Institute University of Milan, Italy"}]},{"given":"Alejandro","family":"Ordas-Bayon","sequence":"additional","affiliation":[{"name":"Servicio de Cirug\u00eda Ortop\u00e9dica y Traumatolog\u00eda, Hospital Universitario Ram\u00f3n y Cajal, Madrid, Spain"}]},{"given":"Andrea","family":"Fidanza","sequence":"additional","affiliation":[{"name":"Orthopaedic and Trauma Unit, Dep. Department of Life, Health and Environmental Sciences - University of L'Aquila, L'Aquila, Italy"}]},{"given":"Yuriy","family":"Rozhko","sequence":"additional","affiliation":[{"name":"Julius Wolff Institute, Berlin Institute of Health at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}]},{"given":"Ekin Kaya","family":"\u015eim\u015fek","sequence":"additional","affiliation":[{"name":"Orthopaedics and Traumatology Specialists, Baskent University Hospital, Ankara, T\u00fcrkiye"}]},{"given":"Eran","family":"Keltz","sequence":"additional","affiliation":[{"name":"Division of Orthopedic Surgery, Rambam Health Care Campus, Haifa, Israel"}]},{"given":"Georg","family":"Osterhoff","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Trauma and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany"}]},{"given":"Philipp","family":"Damm","sequence":"additional","affiliation":[{"name":"Julius Wolff Institute, Berlin Institute of Health at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}]},{"given":"Georg N.","family":"Duda","sequence":"additional","affiliation":[{"name":"Julius Wolff Institute, Berlin Institute of Health at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}]},{"given":"Marko","family":"Leskovar","sequence":"additional","affiliation":[{"name":"Zuse Institute Berlin (ZIB), Berlin, Germany"}]},{"given":"Stefan","family":"Zachow","sequence":"additional","affiliation":[{"name":"Zuse Institute Berlin (ZIB), Berlin, Germany"},{"name":"Department of Oral and Maxillofacial Surgery, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}]},{"given":"Adam","family":"Trepczynski","sequence":"additional","affiliation":[{"name":"Julius Wolff Institute, Berlin Institute of Health at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}]},{"given":"Mark","family":"Heyland","sequence":"additional","affiliation":[{"name":"Julius Wolff Institute, Berlin Institute of Health at Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Germany"}]}],"member":"276","container-title":["Journal of Orthopaedic Trauma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/BOT.0000000000003032","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T22:00:09Z","timestamp":1750888809000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/BOT.0000000000003032"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,24]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1097\/bot.0000000000003032","relation":{},"ISSN":["0890-5339","1531-2291"],"issn-type":[{"value":"0890-5339","type":"print"},{"value":"1531-2291","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,24]]}}}</enrichment>
    <enrichment key="opus_import_origin">crossref</enrichment>
    <enrichment key="opus_doiImportPopulated">PersonAuthorFirstName_1,PersonAuthorLastName_1,PersonAuthorIdentifierOrcid_1,PersonAuthorFirstName_2,PersonAuthorLastName_2,PersonAuthorFirstName_3,PersonAuthorLastName_3,PersonAuthorFirstName_4,PersonAuthorLastName_4,PersonAuthorFirstName_5,PersonAuthorLastName_5,PersonAuthorFirstName_6,PersonAuthorLastName_6,PersonAuthorFirstName_7,PersonAuthorLastName_7,PersonAuthorFirstName_8,PersonAuthorLastName_8,PersonAuthorFirstName_9,PersonAuthorLastName_9,PersonAuthorFirstName_10,PersonAuthorLastName_10,PersonAuthorFirstName_11,PersonAuthorLastName_11,PersonAuthorFirstName_12,PersonAuthorLastName_12,PersonAuthorFirstName_13,PersonAuthorLastName_13,PersonAuthorFirstName_14,PersonAuthorLastName_14,PersonAuthorFirstName_15,PersonAuthorLastName_15,PublisherName,TitleMain_1,Language,TitleAbstract_1,TitleParent_1,PublishedYear,IdentifierIssn</enrichment>
    <enrichment key="PeerReviewed">yes</enrichment>
    <enrichment key="AcceptedDate">2025-06-19</enrichment>
    <enrichment key="opus.source">doi-import</enrichment>
    <author>Dominik Deppe</author>
    <submitter>Stefan Zachow</submitter>
    <author>Matteo Gabriele</author>
    <author>Manuel Giovanni Mazzoleni</author>
    <author>Alejandro Ordas-Bayon</author>
    <author>Andrea Fidanza</author>
    <author>Yuriy Rozhko</author>
    <author>Ekin Kaya Şimşek</author>
    <author>Eran Keltz</author>
    <author>Georg Osterhoff</author>
    <author>Philipp Damm</author>
    <author>Georg N. Duda</author>
    <author>Marko Leskovar</author>
    <author>Stefan Zachow</author>
    <author>Adam Trepczynski</author>
    <author>Mark Heyland</author>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <collection role="projects" number="SFB_1444">SFB_1444</collection>
    <collection role="projects" number="SFB1444">SFB1444</collection>
  </doc>
</export-example>
