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  <doc>
    <id>1274</id>
    <completedYear/>
    <publishedYear/>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>reportzib</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>2011-06-14</completedDate>
    <publishedDate>2011-06-14</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Advances in modelling of the bovine estrous cycle: Administration of PGF2alpha</title>
    <abstract language="eng">Our model of the bovine estrous cycle is a set of ordinary differential equations which generates hormone profiles of successive estrous cycles with several follicular waves per cycle. It describes the growth and decay of the follicles and the corpus luteum, as well as the change of the key substances over time. In this work we describe recent improvements of this model, including the introduction of new components, and elimination of time delays. We validate our model by showing that the simulations agree with observations from synchronization studies and with measured progesterone data after a single dose administration of synthetic prostaglandin F2alpha.</abstract>
    <identifier type="serial">11-17</identifier>
    <identifier type="urn">urn:nbn:de:0297-zib-12740</identifier>
    <enrichment key="SourceTitle">Appeared in: Theriogenology 78 (2012), pp. 1415-1428</enrichment>
    <author>Claudia Stötzel</author>
    <submitter>Claudia Stötzel</submitter>
    <author>Julia Plöntzke</author>
    <author>Susanna Röblitz</author>
    <series>
      <title>ZIB-Report</title>
      <number>11-17</number>
    </series>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>cow</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>reproduction</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>hormone patterns</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>differential equations</value>
    </subject>
    <subject>
      <language>eng</language>
      <type>uncontrolled</type>
      <value>systems biology</value>
    </subject>
    <collection role="msc" number="92C30">Physiology (general)</collection>
    <collection role="msc" number="92C42">Systems biology, networks</collection>
    <collection role="msc" number="92C50">Medical applications (general)</collection>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compsys">Computational Systems Biology</collection>
    <collection role="persons" number="susanna.roeblitz">Röblitz, Susanna</collection>
    <collection role="projects" number="MATHEON-A18">MATHEON-A18</collection>
    <file>https://opus4.kobv.de/opus4-zib/files/1274/ZR_11_17_Bovine_PGF.pdf</file>
  </doc>
</export-example>
