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  <doc>
    <id>8035</id>
    <completedYear/>
    <publishedYear>2020</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>10624</pageFirst>
    <pageLast>10628</pageLast>
    <pageNumber/>
    <edition/>
    <issue>24</issue>
    <volume>142</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Combining Phage Display and Next-generation Sequencing for Materials Sciences: A Case Study on Probing Polypropylene Surfaces</title>
    <abstract language="eng">Phage display biopanning with Illumina next-generation sequencing (NGS) is applied to reveal insights into peptide-based adhesion domains for polypropylene (PP). One biopanning round followed by NGS selects robust PP-binding peptides that are not evident by Sanger sequencing. NGS provides a significant statistical base that enables motif analysis, statistics on positional residue depletion/enrichment, and data analysis to suppress false-positive sequences from amplification bias. The selected sequences are employed as water-based primers for PP?metal adhesion to condition PP surfaces and increase adhesive strength by 100\% relative to nonprimed PP.</abstract>
    <parentTitle language="eng">Journal of the American Chemical Society</parentTitle>
    <identifier type="doi">10.1021/jacs.0c03482</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Carmen Juds</author>
    <submitter>Kalina Tsankova</submitter>
    <author>Johannes Schmidt</author>
    <author>Michael Weller</author>
    <author>Thorid Lange</author>
    <author>Tim Conrad</author>
    <author>Hans Boerner</author>
    <collection role="institutes" number="vis">Visual Data Analysis</collection>
    <collection role="persons" number="conrad">Conrad, Tim</collection>
    <collection role="projects" number="MODAL-MedLab">MODAL-MedLab</collection>
    <collection role="projects" number="MODAL-Gesamt">MODAL-Gesamt</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
  </doc>
</export-example>
