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    <title language="eng">Towards understanding knee joint laxity: Errors in non-invasive assessment of joint rotation can be corrected</title>
    <parentTitle language="eng">Medical Engineering and Physics</parentTitle>
    <identifier type="doi">doi.org/10.1016/j.medengphy.2014.03.017</identifier>
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    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Philippe Moewis</author>
    <submitter> Stoetzel</submitter>
    <author>Heide Boeth</author>
    <author>Markus O. Heller</author>
    <author>Caroline Yntema</author>
    <author>Tobias Jung</author>
    <author>Ralf Doyscher</author>
    <author>Rainald Ehrig</author>
    <author>Yanlin Zhong</author>
    <author>William R. Taylor</author>
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    <collection role="institutes" number="compsys">Computational Systems Biology</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <title language="eng">Muskuloskeletale Belastungen im Schafshinterlauf</title>
    <parentTitle language="eng">Materialwissenschaft und Werkstofftechnik</parentTitle>
    <author>Markus O. Heller</author>
    <author>Georg Duda</author>
    <author>Rainald Ehrig</author>
    <author>H. Schell</author>
    <author>P. Seebeck</author>
    <author>William R. Taylor</author>
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    <title language="eng">Validation of a New Model of Human Knee Kinematics against in Vivo Data under Physiologic Neuromuscular Activation Patterns</title>
    <parentTitle language="eng">Proceedings of the 51th Annual Meeting of the Orthopedic Society</parentTitle>
    <author>Markus O. Heller</author>
    <author>G. Duda</author>
    <author>Christian König</author>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>S. Hinterwimmer</author>
    <author>H. Graichen</author>
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    <pageFirst>1470</pageFirst>
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    <volume>29</volume>
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    <title language="eng">The weighted optimal common shape technique improves identification of the hip joint centre of rotation in vivo</title>
    <parentTitle language="eng">Journal of Orthopedic Research</parentTitle>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Markus O. Heller</author>
    <author>Stefan Kratzenstein</author>
    <author>Rainald Ehrig</author>
    <author>Georgi Wassilew</author>
    <author>Georg Duda</author>
    <author>William R. Taylor</author>
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    <title language="eng">A new model to predict in vivo human knee kinematics under physiological-like muscle activation</title>
    <parentTitle language="eng">Journal of Biomechanics</parentTitle>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Markus O. Heller</author>
    <author>Christian König</author>
    <author>F. Graichen</author>
    <author>S. Hinterwimmer</author>
    <author>Rainald Ehrig</author>
    <author>G. Duda</author>
    <author>William R. Taylor</author>
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    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <publishedYear>2011</publishedYear>
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    <language>eng</language>
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    <issue>7</issue>
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    <title language="eng">The SCoRE residual: A quality index to assess the accuracy of joint estimations</title>
    <parentTitle language="eng">Journal of Biomechanics</parentTitle>
    <identifier type="doi">10.1016/j.jbiomech.2010.12.009</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <author>Stefan Kratzenstein</author>
    <author>Georg Duda</author>
    <author>Adam Trepczynski</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <id>2123</id>
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    <publishedYear>2006</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
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    <pageNumber/>
    <edition/>
    <issue>39</issue>
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    <completedDate>--</completedDate>
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    <title language="eng">A Survey for Formal Methods for Determining the Centre of Ball Joints</title>
    <parentTitle language="eng">Journal of Biomechanics</parentTitle>
    <author>Rainald Ehrig</author>
    <author>William R. Taylor</author>
    <author>G. Duda</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
    <collection role="projects" number="DFG-Knee-Laxity">DFG-Knee-Laxity</collection>
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  <doc>
    <id>2124</id>
    <completedYear>2006</completedYear>
    <publishedYear>2006</publishedYear>
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    <publisherPlace>Chicago</publisherPlace>
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    <completedDate>--</completedDate>
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    <title language="eng">A New Approach for the Determination of Joint Axes</title>
    <parentTitle language="eng">Proceedings of the 52th Annual Meeting of the Orthopedic Society</parentTitle>
    <author>Rainald Ehrig</author>
    <author>William R. Taylor</author>
    <author>G. Duda</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <publishedYear>2007</publishedYear>
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    <language>eng</language>
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    <completedDate>--</completedDate>
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    <title language="eng">A Survey for Formal Methods for Determining Functional Joint Axes</title>
    <parentTitle language="eng">Journal of Biomechanics</parentTitle>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Rainald Ehrig</author>
    <author>William R. Taylor</author>
    <author>Georg Duda</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
    <collection role="projects" number="DFG-Knee-Laxity">DFG-Knee-Laxity</collection>
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    <publishedYear>2009</publishedYear>
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    <language>eng</language>
    <pageFirst/>
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    <publisherPlace>London</publisherPlace>
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    <completedDate>--</completedDate>
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    <title language="eng">An imageless method to quantify the mechanical femoral-tibial angle based on the functional determination of joint centers and axes</title>
    <parentTitle language="eng">Annual meeting of the ESMAC 2009</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>Evgenios I. Kornaropoulos</author>
    <author>William R. Taylor</author>
    <author>Georg Duda</author>
    <author>Rainald Ehrig</author>
    <author>Georg Matziolis</author>
    <author>Michael Müller</author>
    <author>Georgi Wassilew</author>
    <author>Patrick Asbach</author>
    <author>Carsten Perka</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <id>2243</id>
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    <publishedYear>2010</publishedYear>
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    <language>eng</language>
    <pageFirst>204</pageFirst>
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    <pageNumber/>
    <edition/>
    <issue>2</issue>
    <volume>31</volume>
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    <completedDate>--</completedDate>
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    <title language="eng">Frontal plane alignment: An imageless method to predict the mechanical femoral–tibial angle (mFTA) based on functional determination of joint centres and axes</title>
    <parentTitle language="eng">Gait &amp; Posture</parentTitle>
    <identifier type="doi">10.1016/j.gaitpost.2009.10.006</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Evgenios I. Kornaropoulos</author>
    <author>William R. Taylor</author>
    <author>Georg Duda</author>
    <author>Rainald Ehrig</author>
    <author>Georg Matziolis</author>
    <author>Michael Müller</author>
    <author>Georgi Wassilew</author>
    <author>Patrick Asbach</author>
    <author>Carsten Perka</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
    <collection role="projects" number="DFG-Knee-Laxity">DFG-Knee-Laxity</collection>
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    <publishedYear>2009</publishedYear>
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    <language>eng</language>
    <pageFirst/>
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    <pageNumber/>
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    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>London</publisherPlace>
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    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
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    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Reduction of the influence of skin marker artefacts using the optimal common shape technique</title>
    <parentTitle language="eng">Annual meeting of the ESMAC 2009</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>Stefan Kratzenstein</author>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <completedYear>2004</completedYear>
    <publishedYear>2004</publishedYear>
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    <language>eng</language>
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    <pageNumber/>
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    <publisherName/>
    <publisherPlace>Berlin</publisherPlace>
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    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Wie sind Osteosynthesesysteme und Defektzonen in vivo belastet?</title>
    <parentTitle language="eng">68. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie in Verbindung mit dem Deutschen Orthopädenkongress</parentTitle>
    <author>J.-P. Kassi</author>
    <author>William R. Taylor</author>
    <author>J. Schwarzkopf</author>
    <author>H. Schell</author>
    <author>G. Duda</author>
    <author>Rainald Ehrig</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <completedYear>2010</completedYear>
    <publishedYear>2010</publishedYear>
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    <language>eng</language>
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    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>Edinburgh</publisherPlace>
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    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Quantification of Accuracy in Estimating Joint Centers</title>
    <parentTitle language="eng">17th Congress of the European Society of Biomechanics</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>Stefan Kratzenstein</author>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <author>Georg Duda</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <completedYear>2009</completedYear>
    <publishedYear>2009</publishedYear>
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    <language>eng</language>
    <pageFirst/>
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    <pageNumber/>
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    <publisherName/>
    <publisherPlace>Münster</publisherPlace>
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    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
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    <title language="eng">Die Bestimmung der Genauigkeit nicht-invasiver Techniken zur Ermittlung der Hüftgelenksposition in-vivo</title>
    <parentTitle language="eng">6th annual meeting of the German Society for Biomechanics (DGfB)</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>Stefan Kratzenstein</author>
    <author>Markus O. Heller</author>
    <author>Rainald Ehrig</author>
    <author>Georg Duda</author>
    <author>Jörg H. Schröder</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <completedDate>--</completedDate>
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    <title language="eng">Der Vergleich von nicht-invasiven Techniken zur Bestimmung der Hüftgelenksposition</title>
    <parentTitle language="eng">Annual meeting of the German Society of Orthopaedics and Trauma Surgery</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>Stefan Kratzenstein</author>
    <author>Markus O. Heller</author>
    <author>Rainald Ehrig</author>
    <author>Georg Duda</author>
    <author>Jörg H. Schröder</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>New Orleans</publisherPlace>
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    <completedDate>--</completedDate>
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    <title language="eng">The Residual: A Reliable Measure of Accuracy in the Determination of Joint Centers</title>
    <parentTitle language="eng">Transactions Vol. 35, 2010 Annual Meeting of the Orthopedic Society</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>Stefan Kratzenstein</author>
    <author>Markus O. Heller</author>
    <author>Rainald Ehrig</author>
    <author>Georg Duda</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <publisherName/>
    <publisherPlace>Edinburgh</publisherPlace>
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    <completedDate>--</completedDate>
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    <title language="eng">The Hip Joint Centre can be determined to within 3 mm</title>
    <parentTitle language="eng">17th Congress of the European Society of Biomechanics</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>Stefan Kratzenstein</author>
    <author>Markus O. Heller</author>
    <author>Rainald Ehrig</author>
    <author>Georg Duda</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <title language="eng">A new approach for optimally reducing skin marker artifact allows determination of the hip joint center within 3mm</title>
    <parentTitle language="eng">Transactions Vol. 35, 2010 Annual Meeting of the Orthopedic Society</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>Stefan Kratzenstein</author>
    <author>Markus O. Heller</author>
    <author>Rainald Ehrig</author>
    <author>Georgi Wassilew</author>
    <author>Georg Duda</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <language>eng</language>
    <pageFirst>S571</pageFirst>
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    <edition/>
    <issue>39, Suppl. 1</issue>
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    <title language="eng">The determination of joint axes</title>
    <parentTitle language="eng">5. World Congress of Biomechanics, Munich, Journal of Biomechanics</parentTitle>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>G. Duda</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <title language="eng">The Profile of Mechanical Loading is Independent of Fracture Fixation Principle</title>
    <parentTitle language="eng">Proceedings of the 51th Annual Meeting of the Orthopedic Society</parentTitle>
    <author>William R. Taylor</author>
    <author>J.-P. Kassi</author>
    <author>J. Schwarzkopf</author>
    <author>Rainald Ehrig</author>
    <author>H. Schell</author>
    <author>G. Duda</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <language>eng</language>
    <pageFirst>567</pageFirst>
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    <edition/>
    <issue>4</issue>
    <volume>29</volume>
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    <completedDate>--</completedDate>
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    <title language="eng">The medial-lateral force distribution in the ovine stifle joint during walking</title>
    <parentTitle language="eng">Journal of Orthopaedic Research</parentTitle>
    <identifier type="doi">10.1002/jor.21254</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>William R. Taylor</author>
    <author>Berry M. Pöpplau</author>
    <author>Christian König</author>
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    <author>Stefan Zachow</author>
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    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="projects" number="OSSCA">OSSCA</collection>
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    <language>eng</language>
    <pageFirst>1051</pageFirst>
    <pageLast>7</pageLast>
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    <edition/>
    <issue>5</issue>
    <volume>41</volume>
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    <title language="eng">Anterior cruciate ligament-deficient patients with passive knee joint laxity have a decreased range of anterior-posterior motion during active movements</title>
    <parentTitle language="eng">The American Journal of Sports Medicine</parentTitle>
    <identifier type="doi">10.1177/0363546513480465</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Heide Boeth</author>
    <author>Georg Duda</author>
    <author>Markus O. Heller</author>
    <author>Rainald Ehrig</author>
    <author>Ralf Doyscher</author>
    <author>Tobias Jung</author>
    <author>Philippe Moewis</author>
    <author>Sven Scheffler</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="projects" number="DFG-Knee-Laxity">DFG-Knee-Laxity</collection>
    <collection role="projects" number="OSSCA">OSSCA</collection>
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    <title language="eng">The Symmetrical Axis of Rotation Approach (SARA) for Determination of Joint Axes in Clinical Gait Analysis</title>
    <parentTitle language="eng">1st Joint ESMAC-GCMAS Meeting, Amsterdam</parentTitle>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>G. Duda</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <publisherName/>
    <publisherPlace>San Francisco</publisherPlace>
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    <completedDate>--</completedDate>
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    <title language="eng">Can Skin Markers Determine the Kinematics of Underlying Bones?</title>
    <parentTitle language="eng">Proceedings of the 50th Annual Meeting of the Orthopedic Society</parentTitle>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <author>H. Schell</author>
    <author>G. Duda</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <id>2415</id>
    <completedYear>2005</completedYear>
    <publishedYear>2005</publishedYear>
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    <language>eng</language>
    <pageFirst>726</pageFirst>
    <pageLast>734</pageLast>
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    <edition/>
    <issue>23</issue>
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    <completedDate>--</completedDate>
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    <title language="eng">On the Influence of Soft Tissue Coverage in the Determination of Bone Kinematics using Bone Markers</title>
    <parentTitle language="eng">Journal of Orthopedic Research</parentTitle>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <author>H. Schell</author>
    <author>P. Klein</author>
    <author>G. Duda</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
  </doc>
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    <id>2416</id>
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    <publisherName/>
    <publisherPlace>Washington</publisherPlace>
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    <completedDate>--</completedDate>
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    <title language="eng">Animal Models for Knee Injury Frequently Underestimate the Mechanical Conditions of the Clinical Situation</title>
    <parentTitle language="eng">Proceedings of the 51th Annual Meeting of the Orthopedic Society</parentTitle>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <author>H. Schell</author>
    <author>P. Seebeck</author>
    <author>G. Duda</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <id>2417</id>
    <completedYear>2006</completedYear>
    <publishedYear>2006</publishedYear>
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    <language>eng</language>
    <pageFirst>791</pageFirst>
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    <edition/>
    <issue>39</issue>
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    <completedDate>--</completedDate>
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    <title language="eng">Tibio-femoral Joint Contact Forces in Sheep</title>
    <parentTitle language="eng">Journal of Biomechanics</parentTitle>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <author>H. Schell</author>
    <author>P. Seebeck</author>
    <author>G. Duda</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <completedDate>--</completedDate>
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    <title language="eng">Reproducibility of a functional approach to gait analysis</title>
    <parentTitle language="eng">Annual meeting of the ESMAC 2009</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>William R. Taylor</author>
    <author>Evgenios I. Kornaropoulos</author>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <author>Georg Duda</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compmed">Computational Medicine</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <id>2419</id>
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    <completedDate>--</completedDate>
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    <title language="eng">Non-invasive Assessment of Skeletal Kinematics</title>
    <parentTitle language="eng">Measurement and Sensing in Medicine and Health</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>William R. Taylor</author>
    <author>Stefan Kratzenstein</author>
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    <author>Philippe Moewis</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace>Long Beach</publisherPlace>
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    <completedDate>--</completedDate>
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    <title language="eng">Targeted Marker Placement for the Functional Identification of the Hip Joint Centre</title>
    <parentTitle language="eng">Transactions Vol. 36, 2011 Annual Meeting of the Orthopedic Society</parentTitle>
    <enrichment key="PeerReviewed">no</enrichment>
    <author>William R. Taylor</author>
    <author>Evgenios I. Kornaropoulos</author>
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    <author>F. Plank</author>
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    <collection role="projects" number="OSSCA">OSSCA</collection>
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    <id>2421</id>
    <completedYear>2006</completedYear>
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    <language>eng</language>
    <pageFirst>S491</pageFirst>
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    <edition/>
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    <title language="eng">The medio-lateral force distribution in the sheep knee during walking</title>
    <parentTitle language="eng">5. World Congress of Biomechanics, Munich, Journal of Biomechanics</parentTitle>
    <author>William R. Taylor</author>
    <author>Christian König</author>
    <author>A. Speirs</author>
    <author>Rainald Ehrig</author>
    <author>G. Duda</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <completedDate>--</completedDate>
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    <title language="eng">Die medio-laterale Kraftverteilung im Schafsknie</title>
    <parentTitle language="eng">Deutscher Kongress für Orthpädie und Unfallchirurgie, Berlin</parentTitle>
    <author>William R. Taylor</author>
    <author>Christian König</author>
    <author>A. Speirs</author>
    <author>Rainald Ehrig</author>
    <author>G. Duda</author>
    <author>Markus O. Heller</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
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    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
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    <language>eng</language>
    <pageFirst>482</pageFirst>
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    <edition/>
    <issue>3</issue>
    <volume>36</volume>
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    <completedDate>--</completedDate>
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    <title language="eng">Effective marker placement for functional identification of the centre of rotation at the hip</title>
    <parentTitle language="eng">Gait &amp; Posture</parentTitle>
    <identifier type="doi">http://dx.doi.org/10.1016/j.gaitpost.2012.04.011</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Stefan Kratzenstein</author>
    <author>Evgenios I. Kornaropoulos</author>
    <author>Rainald Ehrig</author>
    <author>Markus O. Heller</author>
    <author>Berry M. Pöpplau</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compsys">Computational Systems Biology</collection>
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    <collection role="projects" number="OSSCA">OSSCA</collection>
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    <id>2651</id>
    <completedYear>2012</completedYear>
    <publishedYear>2012</publishedYear>
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    <language>eng</language>
    <pageFirst>39</pageFirst>
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    <publisherName>Department of Health Science and Technology, Aalborg University</publisherName>
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    <title language="eng">Metacarpophalangeal joint stiffness is reduced in patients affected by rheumatoid arthritis after glucocorticoid medication</title>
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    <author>William R. Taylor</author>
    <editor>Uwe Kersting</editor>
    <author>Annika Fröhlich</author>
    <editor>Michael Morlock</editor>
    <author>Frank Buttgereit</author>
    <editor>Daniela Jirova-Enzmann</editor>
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    <editor>Kim Dremstrup</editor>
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    <collection role="projects" number="MorningStiffness">MorningStiffness</collection>
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    <title language="eng">Frontal plane lower limb alignment using functionally determined joint centers and axes</title>
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    <title language="eng">Impact of the external knee flexion moment on patello-femoral loading derived from in vivo loads and kinematics</title>
    <abstract language="eng">Introduction: Anterior knee pain and other patello-femoral (PF) complications frequently limit the success of total knee arthroplasty as the final treatment of end stage osteoarthritis. However, knowledge about the in-vivo loading conditions at the PF joint remains limited, as no direct measurements are available. We hypothesised that the external knee flexion moment (EFM) is highly predictive of the PF contact forces during activities with substantial flexion of the loaded knee.&#13;
Materials and methods: Six patients (65–80 years, 67–101 kg) with total knee arthroplasty (TKA) performed two activities of daily living: sit-stand-sit and squat. Tibio-femoral (TF) contact forces were measured in vivo using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The relationship between the EFM and the PF contact force was quantified using linear regression.&#13;
Results: Mean peak TF contact forces of 1.97–3.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). The peak EFM ranged from 3.2 to 5.9 %BW times body height, and was a good predictor of the PF contact force (R2 = 0.95 and 0.88 for sit-stand-sit and squat, respectively).&#13;
Discussion: The novel combination of in vivo TF contact forces and internal patellar kinematics enabled a reliable assessment of PF contact forces. The results of the regression analysis suggest that PF forces can be estimated based solely on the EFM from quantitative gait analysis. Our study also demonstrates the relevance of PF contact forces, which reach magnitudes similar to TF forces during activities of daily living.</abstract>
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Tibio-femoral (TF) contact forces were measured &lt;jats:italic&gt;in vivo&lt;\/jats:italic&gt; using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The relationship between the EFM and the PF contact force was quantified using linear regression.&lt;\/jats:p&gt;&lt;\/jats:sec&gt;&lt;jats:sec&gt;&lt;jats:title&gt;Results&lt;\/jats:title&gt;&lt;jats:p&gt;Mean peak TF contact forces of 1.97\u20133.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). 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    <author>Barbara Postolka</author>
    <author>Michael A. R. Freeman</author>
    <author>William R. Taylor</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compsys">Computational Systems Biology</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
    <collection role="projects" number="OSSCA">OSSCA</collection>
  </doc>
  <doc>
    <id>5194</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">A Novel Approach to Quantify Morning Stiffness in Patients with Rheumatoid Arthritis</title>
    <parentTitle language="eng">Annual European Congress of Rheumatology, EULAR 2015, Rome</parentTitle>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Heide Boeth</author>
    <submitter> Stötzel</submitter>
    <author>Georg Duda</author>
    <author>Daniel Hinzmann</author>
    <author>Sandra Hermann</author>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>Tom Witaschek</author>
    <author>Frank Buttgereit</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compsys">Computational Systems Biology</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
    <collection role="projects" number="MorningStiffness">MorningStiffness</collection>
  </doc>
  <doc>
    <id>5632</id>
    <completedYear/>
    <publishedYear>2015</publishedYear>
    <thesisYearAccepted/>
    <language>deu</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume/>
    <type>conferenceobject</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="deu">Objektive Quantifizierung der Morgensteifigkeit als Parameter für rheumatoide Arthritis im Metacarpophalangealgelenk</title>
    <parentTitle language="deu">9. Jahrestagung der Deutschen Gesellschaft für Biomechanik (DGfB), Bonn</parentTitle>
    <enrichment key="PeerReviewed">yes</enrichment>
    <author>Heide Boeth</author>
    <submitter>Mascha Berg</submitter>
    <author>Georg Duda</author>
    <author>Daniel Hinzmann</author>
    <author>William R. Taylor</author>
    <author>Rainald Ehrig</author>
    <author>Tom Witaschek</author>
    <author>Frank Buttgereit</author>
    <collection role="institutes" number="num">Numerical Mathematics</collection>
    <collection role="institutes" number="compsys">Computational Systems Biology</collection>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
    <collection role="projects" number="MorningStiffness">MorningStiffness</collection>
  </doc>
  <doc>
    <id>8221</id>
    <completedYear>2021</completedYear>
    <publishedYear>2021</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst>5282</pageFirst>
    <pageLast>5291</pageLast>
    <pageNumber/>
    <edition/>
    <issue>11</issue>
    <volume>60</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>2021-04-05</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Quantification of morning stiffness to assess disease activity and treatment effects in rheumatoid arthritis</title>
    <abstract language="eng">Objectives&#13;
&#13;
The clinical parameter “morning stiffness” is widely used to assess the status of rheumatoid arthritis (RA), but its accurate quantitative assessment in a clinical setting has not yet been successful. This lack of individual quantification limits both personalized medication and efficacy evaluation in the treatment of RA.&#13;
Methods&#13;
&#13;
We have developed a novel technology to assess passive resistance of the metacarpophalangeal (MCP) III joint (stiffness) and its Passive Range of Motion (PRoM). Within this pilot study, nineteen female postmenopausal RA patients and nine healthy controls were examined in the evening as well as in the morning of the following day. To verify the specificity of the biomechanical quantification, eleven patients with RA were assessed both prior to and ∼3 h after glucocorticoid therapy.&#13;
Results&#13;
&#13;
While the healthy controls showed only minor changes between afternoon and morning, in RA patients mean±SD PRoM decreased significantly by 18 ± 22% and stiffness increased significantly by 20 ± 18% in the morning compared with the previous afternoon. We found a significant positive correlation between RA activity and biomechanical measures. Glucocorticoids significantly increased mean PRoM by 16 ± 11% and reduced mean stiffness by 23 ± 22%.&#13;
Conclusion&#13;
&#13;
This technology allowed mechanical stiffness to be quantified in MCP joints, and has demonstrated high sensitivity in respect to disease status as well as medication effect in RA patients. Such non-invasive, low risk, and rapid assessment of biomechanical joint stiffness opens a novel avenue for judging therapy efficacy in patients with RA, and potentially also in other non-RA inflammatory joint diseases.</abstract>
    <parentTitle language="eng">Rheumatology</parentTitle>
    <identifier type="doi">10.1093/rheumatology/keab323</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <enrichment key="AcceptedDate">05.04.2021</enrichment>
    <author>Heide Boeth</author>
    <submitter>Rainald Ehrig</submitter>
    <author>Robert Biesen</author>
    <author>Jeremias Hollnagel</author>
    <author>Sandra Herrmann</author>
    <author>Rainald Ehrig</author>
    <author>Lorenzo Pelli</author>
    <author>William R. Taylor</author>
    <author>Georg Duda</author>
    <author>Frank Buttgereit</author>
    <collection role="persons" number="ehrig">Ehrig, Rainald</collection>
    <collection role="projects" number="MorningStiffness">MorningStiffness</collection>
    <collection role="institutes" number="MSoCP">Modeling and Simulation of Complex Processes</collection>
  </doc>
  <doc>
    <id>9908</id>
    <completedYear/>
    <publishedYear>2024</publishedYear>
    <thesisYearAccepted/>
    <language>eng</language>
    <pageFirst/>
    <pageLast/>
    <pageNumber/>
    <edition/>
    <issue/>
    <volume>12</volume>
    <type>article</type>
    <publisherName/>
    <publisherPlace/>
    <creatingCorporation/>
    <contributingCorporation/>
    <belongsToBibliography>0</belongsToBibliography>
    <completedDate>--</completedDate>
    <publishedDate>--</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Impact of the External Knee Flexion Moment on Patello-Femoral Loading Derived from in vivo Loads and Kinematics</title>
    <abstract language="eng">Anterior knee pain and other patello-femoral (PF) complications frequently limit the success of total knee arthroplasty as the final treatment of end stage osteoarthritis. However, knowledge about the invivo loading conditions at the PF joint remains limited, as no direct measurements are available. We hypothesised that the external knee flexion moment (EFM) is highly predictive of the PF contact forces during activities with substantial flexion of the loaded knee.Six patients (65-80 years, 67-101 kg) with total knee arthroplasty (TKA) performed two activities of daily living: sit-stand-sit and squat. Tibio-femoral (TF) contact forces were measured in vivo using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The&#13;
relationship between the EFM and the PF contact force was quantified using linear regression.Mean peak TF contact forces of 1.97 to 3.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). The peak EFM ranged from 3.2 to 5.9 %BW times body height, and was a good predictor of the PF contact force (R^2 = 0.95 and 0.88 for sit-standsit and squat, respectively).The novel combination of in vivo TF contact forces and internal patellar kinematics enabled a reliable assessment of PF contact forces. The results of the regression analysis suggest that PF forces can be estimated based solely on the EFM from quantitative gait analysis. Our study also demonstrates the relevance of PF contact forces, which reach magnitudes similar to TF forces during activities of daily living.</abstract>
    <parentTitle language="eng">Frontiers in Bioengineering and Biotechnology</parentTitle>
    <identifier type="doi">10.3389/fbioe.2024.1473951</identifier>
    <enrichment key="PeerReviewed">yes</enrichment>
    <enrichment key="AcceptedDate">20.12.2024</enrichment>
    <enrichment key="opus.source">publish</enrichment>
    <author>Adam Trepczynski</author>
    <submitter>Stefan Zachow</submitter>
    <author>Paul Kneifel</author>
    <author>Mark Heyland</author>
    <author>Marko Leskovar</author>
    <author>Philippe Moewis</author>
    <author>Philipp Damm</author>
    <author>William R. Taylor</author>
    <author>Stefan Zachow</author>
    <author>Georg Duda</author>
    <collection role="persons" number="zachow">Zachow, Stefan</collection>
    <collection role="institutes" number="VDcC">Visual and Data-centric Computing</collection>
    <collection role="projects" number="SFB1444">SFB1444</collection>
  </doc>
</export-example>
