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    <id>295</id>
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    <completedDate>1997-06-19</completedDate>
    <publishedDate>1997-06-19</publishedDate>
    <thesisDateAccepted>--</thesisDateAccepted>
    <title language="eng">Hyperthermia Treatment Planning in Clinical Cancer Therapy: Modelling, Simulation and Visualization</title>
    <abstract language="eng">\noindent The speaker and his co-workers in Scientific Computing and Visualization have established a close cooperation with medical doctors at the Rudolf--Virchow--Klinikum of the Humboldt University in Berlin on the topic of regional hyperthermia. In order to permit a patient--specific treatment planning, a special software system ({\sf\small HyperPlan}) has been developed. \noindent A mathematical model of the clinical system ({\it radio frequency applicator with 8 antennas, water bolus, individual patient body}) involves Maxwell's equations in inhomogeneous media and a so--called bio--heat transfer PDE describing the temperature distribution in the human body. The electromagnetic field and the thermal phenomena need to be computed at a speed suitable for the clinical environment. An individual geometric patient model is generated as a quite complicated tetrahedral ``coarse'' grid (several thousands of nodes). Both Maxwell's equations and the bio--heat transfer equation are solved on that 3D--grid by means of {\em adaptive} multilevel finite element methods, which automatically refine the grid where necessary in view of the required accuracy. Finally optimal antenna parameters for the applicator are determined . \noindent All steps of the planning process are supported by powerful visualization methods. Medical images, contours, grids, simulated electromagnetic fields and temperature distributions can be displayed in combination. A number of new algorithms and techniques had to be developed and implemented. Special emphasis has been put on advanced 3D interaction methods and user interface issues.</abstract>
    <identifier type="serial">SC-97-26</identifier>
    <identifier type="opus3-id">296</identifier>
    <identifier type="urn">urn:nbn:de:0297-zib-2958</identifier>
    <enrichment key="SourceTitle">Appeared in: Proc. of the 15th IMACS World Congress 1997 on Scientific Compuation: Modelling and Applied Mathematics. A. Sydow (ed.) Wissenschaft und Technik Verlag, 1997, Vol. 3, pp. 9-17</enrichment>
    <author>Peter Deuflhard</author>
    <author>Martin Seebass</author>
    <author>Detlev Stalling</author>
    <author>Rudolf Beck</author>
    <author>Hans-Christian Hege</author>
    <series>
      <title>ZIB-Report</title>
      <number>SC-97-26</number>
    </series>
    <collection role="ddc" number="000">Informatik, Informationswissenschaft, allgemeine Werke</collection>
    <collection role="institutes" number="">ZIB Allgemein</collection>
    <collection role="persons" number="deuflhard">Deuflhard, Peter</collection>
    <collection role="persons" number="hege">Hege, Hans-Christian</collection>
    <file>https://opus4.kobv.de/opus4-zib/files/295/SC-97-26.ps</file>
    <file>https://opus4.kobv.de/opus4-zib/files/295/SC-97-26.pdf</file>
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