@inproceedings{HajizadehSchuetzListetal.2015, author = {Hajizadeh, Maryam and Sch{\"u}tz, Pascal and List, Renate and Boeth, Heide and Ehrig, Rainald and Postolka, Barbara and Freeman, Michael A. R. and Taylor, William R.}, title = {Interpretation of tibio-femoral kinematics critically depends upon the kinematic analysis approach}, booktitle = {ISB 2015, 25th congress of the International Society of Biomechanics, Glasgow}, year = {2015}, language = {en} } @article{MoewisBoethHelleretal.2014, author = {Moewis, Philippe and Boeth, Heide and Heller, Markus O. and Yntema, Caroline and Jung, Tobias and Doyscher, Ralf and Ehrig, Rainald and Zhong, Yanlin and Taylor, William R.}, title = {Towards understanding knee joint laxity: Errors in non-invasive assessment of joint rotation can be corrected}, volume = {36}, journal = {Medical Engineering and Physics}, number = {7}, doi = {doi.org/10.1016/j.medengphy.2014.03.017}, pages = {889 -- 895}, year = {2014}, language = {en} } @article{HellerDudaEhrigetal.2005, author = {Heller, Markus O. and Duda, Georg and Ehrig, Rainald and Schell, H. and Seebeck, P. and Taylor, William R.}, title = {Muskuloskeletale Belastungen im Schafshinterlauf}, journal = {Materialwissenschaft und Werkstofftechnik}, number = {36}, pages = {775 -- 780}, year = {2005}, language = {en} } @inproceedings{HellerDudaKoenigetal.2005, author = {Heller, Markus O. and Duda, G. and K{\"o}nig, Christian and Taylor, William R. and Ehrig, Rainald and Hinterwimmer, S. and Graichen, H.}, title = {Validation of a New Model of Human Knee Kinematics against in Vivo Data under Physiologic Neuromuscular Activation Patterns}, booktitle = {Proceedings of the 51th Annual Meeting of the Orthopedic Society}, address = {Washington}, year = {2005}, language = {en} } @article{HellerKratzensteinEhrigetal.2011, author = {Heller, Markus O. and Kratzenstein, Stefan and Ehrig, Rainald and Wassilew, Georgi and Duda, Georg and Taylor, William R.}, title = {The weighted optimal common shape technique improves identification of the hip joint centre of rotation in vivo}, volume = {29}, journal = {Journal of Orthopedic Research}, pages = {1470 -- 5}, year = {2011}, language = {en} } @article{HellerKoenigGraichenetal.2007, author = {Heller, Markus O. and K{\"o}nig, Christian and Graichen, F. and Hinterwimmer, S. and Ehrig, Rainald and Duda, G. and Taylor, William R.}, title = {A new model to predict in vivo human knee kinematics under physiological-like muscle activation}, journal = {Journal of Biomechanics}, pages = {45 -- 53}, year = {2007}, language = {en} } @article{EhrigHellerKratzensteinetal.2011, author = {Ehrig, Rainald and Heller, Markus O. and Kratzenstein, Stefan and Duda, Georg and Trepczynski, Adam and Taylor, William R.}, title = {The SCoRE residual: A quality index to assess the accuracy of joint estimations}, volume = {44}, journal = {Journal of Biomechanics}, number = {7}, doi = {10.1016/j.jbiomech.2010.12.009}, pages = {1400 -- 1404}, year = {2011}, language = {en} } @article{EhrigTaylorDudaetal.2006, author = {Ehrig, Rainald and Taylor, William R. and Duda, G. and Heller, Markus O.}, title = {A Survey for Formal Methods for Determining the Centre of Ball Joints}, journal = {Journal of Biomechanics}, number = {39}, pages = {2798 -- 2809}, year = {2006}, language = {en} } @inproceedings{EhrigTaylorDudaetal.2006, author = {Ehrig, Rainald and Taylor, William R. and Duda, G. and Heller, Markus O.}, title = {A New Approach for the Determination of Joint Axes}, booktitle = {Proceedings of the 52th Annual Meeting of the Orthopedic Society}, address = {Chicago}, year = {2006}, language = {en} } @article{EhrigTaylorDudaetal.2007, author = {Ehrig, Rainald and Taylor, William R. and Duda, Georg and Heller, Markus O.}, title = {A Survey for Formal Methods for Determining Functional Joint Axes}, journal = {Journal of Biomechanics}, pages = {2150 -- 2157}, year = {2007}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Matziolis, Georg and M{\"u}ller, Michael and Wassilew, Georgi and Asbach, Patrick and Perka, Carsten and Heller, Markus O.}, title = {An imageless method to quantify the mechanical femoral-tibial angle based on the functional determination of joint centers and axes}, booktitle = {Annual meeting of the ESMAC 2009}, address = {London}, year = {2009}, language = {en} } @article{KornaropoulosTaylorDudaetal.2010, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Matziolis, Georg and M{\"u}ller, Michael and Wassilew, Georgi and Asbach, Patrick and Perka, Carsten and Heller, Markus O.}, title = {Frontal plane alignment: An imageless method to predict the mechanical femoral-tibial angle (mFTA) based on functional determination of joint centres and axes}, volume = {31}, journal = {Gait \& Posture}, number = {2}, doi = {10.1016/j.gaitpost.2009.10.006}, pages = {204 -- 208}, year = {2010}, language = {en} } @inproceedings{KratzensteinTaylorEhrigetal.2009, author = {Kratzenstein, Stefan and Taylor, William R. and Ehrig, Rainald and Heller, Markus O.}, title = {Reduction of the influence of skin marker artefacts using the optimal common shape technique}, booktitle = {Annual meeting of the ESMAC 2009}, address = {London}, year = {2009}, language = {en} } @inproceedings{KassiTaylorSchwarzkopfetal.2004, author = {Kassi, J.-P. and Taylor, William R. and Schwarzkopf, J. and Schell, H. and Duda, G. and Ehrig, Rainald}, title = {Wie sind Osteosynthesesysteme und Defektzonen in vivo belastet?}, booktitle = {68. Jahrestagung der Deutschen Gesellschaft f{\"u}r Unfallchirurgie in Verbindung mit dem Deutschen Orthop{\"a}denkongress}, address = {Berlin}, year = {2004}, language = {en} } @inproceedings{KratzensteinEhrigHelleretal.2010, author = {Kratzenstein, Stefan and Ehrig, Rainald and Heller, Markus O. and Duda, Georg and Taylor, William R.}, title = {A Quantification of Accuracy in Estimating Joint Centers}, booktitle = {17th Congress of the European Society of Biomechanics}, address = {Edinburgh}, year = {2010}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2009, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Duda, Georg and Schr{\"o}der, J{\"o}rg H. and Taylor, William R.}, title = {Die Bestimmung der Genauigkeit nicht-invasiver Techniken zur Ermittlung der H{\"u}ftgelenksposition in-vivo}, booktitle = {6th annual meeting of the German Society for Biomechanics (DGfB)}, address = {M{\"u}nster}, year = {2009}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2009, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Duda, Georg and Schr{\"o}der, J{\"o}rg H. and Taylor, William R.}, title = {Der Vergleich von nicht-invasiven Techniken zur Bestimmung der H{\"u}ftgelenksposition}, booktitle = {Annual meeting of the German Society of Orthopaedics and Trauma Surgery}, address = {Berlin}, year = {2009}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2010, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Duda, Georg and Taylor, William R.}, title = {The Residual: A Reliable Measure of Accuracy in the Determination of Joint Centers}, booktitle = {Transactions Vol. 35, 2010 Annual Meeting of the Orthopedic Society}, address = {New Orleans}, year = {2010}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2010, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Duda, Georg and Taylor, William R.}, title = {The Hip Joint Centre can be determined to within 3 mm}, booktitle = {17th Congress of the European Society of Biomechanics}, address = {Edinburgh}, year = {2010}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2010, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Wassilew, Georgi and Duda, Georg and Taylor, William R.}, title = {A new approach for optimally reducing skin marker artifact allows determination of the hip joint center within 3mm}, booktitle = {Transactions Vol. 35, 2010 Annual Meeting of the Orthopedic Society}, address = {New Orleans}, year = {2010}, language = {en} } @inproceedings{TaylorEhrigDudaetal.2006, author = {Taylor, William R. and Ehrig, Rainald and Duda, G. and Heller, Markus O.}, title = {The determination of joint axes}, booktitle = {5. World Congress of Biomechanics, Munich, Journal of Biomechanics}, number = {39, Suppl. 1}, pages = {S571 -- S572}, year = {2006}, language = {en} } @inproceedings{TaylorKassiSchwarzkopfetal.2005, author = {Taylor, William R. and Kassi, J.-P. and Schwarzkopf, J. and Ehrig, Rainald and Schell, H. and Duda, G.}, title = {The Profile of Mechanical Loading is Independent of Fracture Fixation Principle}, booktitle = {Proceedings of the 51th Annual Meeting of the Orthopedic Society}, address = {Washington}, year = {2005}, language = {en} } @article{TaylorPoepplauKoenigetal.2011, author = {Taylor, William R. and P{\"o}pplau, Berry M. and K{\"o}nig, Christian and Ehrig, Rainald and Zachow, Stefan and Duda, Georg and Heller, Markus O.}, title = {The medial-lateral force distribution in the ovine stifle joint during walking}, volume = {29}, journal = {Journal of Orthopaedic Research}, number = {4}, doi = {10.1002/jor.21254}, pages = {567 -- 571}, year = {2011}, language = {en} } @article{BoethDudaHelleretal.2013, author = {Boeth, Heide and Duda, Georg and Heller, Markus O. and Ehrig, Rainald and Doyscher, Ralf and Jung, Tobias and Moewis, Philippe and Scheffler, Sven and Taylor, William R.}, title = {Anterior cruciate ligament-deficient patients with passive knee joint laxity have a decreased range of anterior-posterior motion during active movements}, volume = {41}, journal = {The American Journal of Sports Medicine}, number = {5}, doi = {10.1177/0363546513480465}, pages = {1051 -- 7}, year = {2013}, language = {en} } @inproceedings{TaylorEhrigDudaetal.2006, author = {Taylor, William R. and Ehrig, Rainald and Duda, G. and Heller, Markus O.}, title = {The Symmetrical Axis of Rotation Approach (SARA) for Determination of Joint Axes in Clinical Gait Analysis}, booktitle = {1st Joint ESMAC-GCMAS Meeting, Amsterdam}, year = {2006}, language = {en} } @inproceedings{TaylorEhrigHelleretal.2004, author = {Taylor, William R. and Ehrig, Rainald and Heller, Markus O. and Schell, H. and Duda, G.}, title = {Can Skin Markers Determine the Kinematics of Underlying Bones?}, booktitle = {Proceedings of the 50th Annual Meeting of the Orthopedic Society}, address = {San Francisco}, year = {2004}, language = {en} } @article{TaylorEhrigHelleretal.2005, author = {Taylor, William R. and Ehrig, Rainald and Heller, Markus O. and Schell, H. and Klein, P. and Duda, G.}, title = {On the Influence of Soft Tissue Coverage in the Determination of Bone Kinematics using Bone Markers}, journal = {Journal of Orthopedic Research}, number = {23}, pages = {726 -- 734}, year = {2005}, language = {en} } @inproceedings{TaylorEhrigHelleretal.2005, author = {Taylor, William R. and Ehrig, Rainald and Heller, Markus O. and Schell, H. and Seebeck, P. and Duda, G.}, title = {Animal Models for Knee Injury Frequently Underestimate the Mechanical Conditions of the Clinical Situation}, booktitle = {Proceedings of the 51th Annual Meeting of the Orthopedic Society}, address = {Washington}, year = {2005}, language = {en} } @article{TaylorEhrigHelleretal.2006, author = {Taylor, William R. and Ehrig, Rainald and Heller, Markus O. and Schell, H. and Seebeck, P. and Duda, G.}, title = {Tibio-femoral Joint Contact Forces in Sheep}, journal = {Journal of Biomechanics}, number = {39}, pages = {791 -- 798}, year = {2006}, language = {en} } @inproceedings{TaylorKornaropoulosEhrigetal.2009, author = {Taylor, William R. and Kornaropoulos, Evgenios I. and Ehrig, Rainald and Heller, Markus O. and Duda, Georg}, title = {Reproducibility of a functional approach to gait analysis}, booktitle = {Annual meeting of the ESMAC 2009}, address = {London}, year = {2009}, language = {en} } @inproceedings{TaylorKratzensteinKornaropoulosetal.2009, author = {Taylor, William R. and Kratzenstein, Stefan and Kornaropoulos, Evgenios I. and Ehrig, Rainald and Moewis, Philippe and Heller, Markus O.}, title = {Non-invasive Assessment of Skeletal Kinematics}, booktitle = {Measurement and Sensing in Medicine and Health}, address = {London}, year = {2009}, language = {en} } @inproceedings{TaylorKornaropoulosKratzensteinetal.2011, author = {Taylor, William R. and Kornaropoulos, Evgenios I. and Kratzenstein, Stefan and Ehrig, Rainald and Plank, F. and Heller, Markus O.}, title = {Targeted Marker Placement for the Functional Identification of the Hip Joint Centre}, booktitle = {Transactions Vol. 36, 2011 Annual Meeting of the Orthopedic Society}, address = {Long Beach}, year = {2011}, language = {en} } @inproceedings{TaylorKoenigSpeirsetal.2006, author = {Taylor, William R. and K{\"o}nig, Christian and Speirs, A. and Ehrig, Rainald and Duda, G. and Heller, Markus O.}, title = {The medio-lateral force distribution in the sheep knee during walking}, booktitle = {5. World Congress of Biomechanics, Munich, Journal of Biomechanics}, number = {39, Suppl. 1}, pages = {S491}, year = {2006}, language = {en} } @inproceedings{TaylorKoenigSpeirsetal.2006, author = {Taylor, William R. and K{\"o}nig, Christian and Speirs, A. and Ehrig, Rainald and Duda, G. and Heller, Markus O.}, title = {Die medio-laterale Kraftverteilung im Schafsknie}, booktitle = {Deutscher Kongress f{\"u}r Orthp{\"a}die und Unfallchirurgie, Berlin}, year = {2006}, language = {en} } @article{KratzensteinKornaropoulosEhrigetal.2012, author = {Kratzenstein, Stefan and Kornaropoulos, Evgenios I. and Ehrig, Rainald and Heller, Markus O. and P{\"o}pplau, Berry M. and Taylor, William R.}, title = {Effective marker placement for functional identification of the centre of rotation at the hip}, volume = {36}, journal = {Gait \& Posture}, number = {3}, doi = {http://dx.doi.org/10.1016/j.gaitpost.2012.04.011}, pages = {482 -- 486}, year = {2012}, language = {en} } @inproceedings{TaylorFroehlichButtgereitetal.2012, author = {Taylor, William R. and Fr{\"o}hlich, Annika and Buttgereit, Frank and Ehrig, Rainald and Witaschek, Tom and Duda, Georg}, title = {Metacarpophalangeal joint stiffness is reduced in patients affected by rheumatoid arthritis after glucocorticoid medication}, booktitle = {Proceedings of the ESM-2012, Aalborg}, editor = {Kersting, Uwe and Morlock, Michael and Jirova-Enzmann, Daniela and Dremstrup, Kim}, publisher = {Department of Health Science and Technology, Aalborg University}, pages = {39}, year = {2012}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Heller, Markus O.}, title = {Frontal plane lower limb alignment using functionally determined joint centers and axes}, booktitle = {International Conference on Computational Bioengineering}, year = {2009}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Heller, Markus O.}, title = {An imageless method to quantify the Mechanical Femoral-Tibial Angle (MFTA) using functionally defined joint centers and axes.}, booktitle = {6th Annual meeting of the German Society for Biomechanics (DGfB)}, year = {2009}, language = {en} } @article{BoethDudaHinzmannetal.2015, author = {Boeth, Heide and Duda, Georg and Hinzmann, Daniel and Hermann, Sandra and Taylor, William R. and Ehrig, Rainald and Witaschek, Tom and Buttgereit, Frank}, title = {A Novel Approach to Quantify Morning Stiffness in Patients with Rheumatoid Arthritis}, journal = {Annual European Congress of Rheumatology, EULAR 2015, Rome}, year = {2015}, language = {en} } @inproceedings{BoethDudaHinzmannetal.2015, author = {Boeth, Heide and Duda, Georg and Hinzmann, Daniel and Taylor, William R. and Ehrig, Rainald and Witaschek, Tom and Buttgereit, Frank}, title = {Objektive Quantifizierung der Morgensteifigkeit als Parameter f{\"u}r rheumatoide Arthritis im Metacarpophalangealgelenk}, booktitle = {9. Jahrestagung der Deutschen Gesellschaft f{\"u}r Biomechanik (DGfB), Bonn}, year = {2015}, language = {de} } @article{BoethBiesenHollnageletal.2021, author = {Boeth, Heide and Biesen, Robert and Hollnagel, Jeremias and Herrmann, Sandra and Ehrig, Rainald and Pelli, Lorenzo and Taylor, William R. and Duda, Georg and Buttgereit, Frank}, title = {Quantification of morning stiffness to assess disease activity and treatment effects in rheumatoid arthritis}, volume = {60}, journal = {Rheumatology}, number = {11}, doi = {10.1093/rheumatology/keab323}, pages = {5282 -- 5291}, year = {2021}, abstract = {Objectives The clinical parameter "morning stiffness" is widely used to assess the status of rheumatoid arthritis (RA), but its accurate quantitative assessment in a clinical setting has not yet been successful. This lack of individual quantification limits both personalized medication and efficacy evaluation in the treatment of RA. Methods We have developed a novel technology to assess passive resistance of the metacarpophalangeal (MCP) III joint (stiffness) and its Passive Range of Motion (PRoM). Within this pilot study, nineteen female postmenopausal RA patients and nine healthy controls were examined in the evening as well as in the morning of the following day. To verify the specificity of the biomechanical quantification, eleven patients with RA were assessed both prior to and ∼3 h after glucocorticoid therapy. Results While the healthy controls showed only minor changes between afternoon and morning, in RA patients mean±SD PRoM decreased significantly by 18 ± 22\% and stiffness increased significantly by 20 ± 18\% in the morning compared with the previous afternoon. We found a significant positive correlation between RA activity and biomechanical measures. Glucocorticoids significantly increased mean PRoM by 16 ± 11\% and reduced mean stiffness by 23 ± 22\%. Conclusion This technology allowed mechanical stiffness to be quantified in MCP joints, and has demonstrated high sensitivity in respect to disease status as well as medication effect in RA patients. Such non-invasive, low risk, and rapid assessment of biomechanical joint stiffness opens a novel avenue for judging therapy efficacy in patients with RA, and potentially also in other non-RA inflammatory joint diseases.}, language = {en} }