@article{HellerDudaEhrigetal.2005, author = {Heller, Markus O. and Duda, Georg and Ehrig, Rainald and Schell, H. and Seebeck, P. and Taylor, William R.}, title = {Muskuloskeletale Belastungen im Schafshinterlauf}, journal = {Materialwissenschaft und Werkstofftechnik}, number = {36}, pages = {775 -- 780}, year = {2005}, language = {en} } @article{HellerKratzensteinEhrigetal.2011, author = {Heller, Markus O. and Kratzenstein, Stefan and Ehrig, Rainald and Wassilew, Georgi and Duda, Georg and Taylor, William R.}, title = {The weighted optimal common shape technique improves identification of the hip joint centre of rotation in vivo}, volume = {29}, journal = {Journal of Orthopedic Research}, pages = {1470 -- 5}, year = {2011}, language = {en} } @article{EhrigHellerKratzensteinetal.2011, author = {Ehrig, Rainald and Heller, Markus O. and Kratzenstein, Stefan and Duda, Georg and Trepczynski, Adam and Taylor, William R.}, title = {The SCoRE residual: A quality index to assess the accuracy of joint estimations}, volume = {44}, journal = {Journal of Biomechanics}, number = {7}, doi = {10.1016/j.jbiomech.2010.12.009}, pages = {1400 -- 1404}, year = {2011}, language = {en} } @article{EhrigTaylorDudaetal.2007, author = {Ehrig, Rainald and Taylor, William R. and Duda, Georg and Heller, Markus O.}, title = {A Survey for Formal Methods for Determining Functional Joint Axes}, journal = {Journal of Biomechanics}, pages = {2150 -- 2157}, year = {2007}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Matziolis, Georg and M{\"u}ller, Michael and Wassilew, Georgi and Asbach, Patrick and Perka, Carsten and Heller, Markus O.}, title = {An imageless method to quantify the mechanical femoral-tibial angle based on the functional determination of joint centers and axes}, booktitle = {Annual meeting of the ESMAC 2009}, address = {London}, year = {2009}, language = {en} } @article{KornaropoulosTaylorDudaetal.2010, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Matziolis, Georg and M{\"u}ller, Michael and Wassilew, Georgi and Asbach, Patrick and Perka, Carsten and Heller, Markus O.}, title = {Frontal plane alignment: An imageless method to predict the mechanical femoral-tibial angle (mFTA) based on functional determination of joint centres and axes}, volume = {31}, journal = {Gait \& Posture}, number = {2}, doi = {10.1016/j.gaitpost.2009.10.006}, pages = {204 -- 208}, year = {2010}, language = {en} } @inproceedings{KratzensteinEhrigHelleretal.2010, author = {Kratzenstein, Stefan and Ehrig, Rainald and Heller, Markus O. and Duda, Georg and Taylor, William R.}, title = {A Quantification of Accuracy in Estimating Joint Centers}, booktitle = {17th Congress of the European Society of Biomechanics}, address = {Edinburgh}, year = {2010}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2009, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Duda, Georg and Schr{\"o}der, J{\"o}rg H. and Taylor, William R.}, title = {Die Bestimmung der Genauigkeit nicht-invasiver Techniken zur Ermittlung der H{\"u}ftgelenksposition in-vivo}, booktitle = {6th annual meeting of the German Society for Biomechanics (DGfB)}, address = {M{\"u}nster}, year = {2009}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2009, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Duda, Georg and Schr{\"o}der, J{\"o}rg H. and Taylor, William R.}, title = {Der Vergleich von nicht-invasiven Techniken zur Bestimmung der H{\"u}ftgelenksposition}, booktitle = {Annual meeting of the German Society of Orthopaedics and Trauma Surgery}, address = {Berlin}, year = {2009}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2010, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Duda, Georg and Taylor, William R.}, title = {The Residual: A Reliable Measure of Accuracy in the Determination of Joint Centers}, booktitle = {Transactions Vol. 35, 2010 Annual Meeting of the Orthopedic Society}, address = {New Orleans}, year = {2010}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2010, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Duda, Georg and Taylor, William R.}, title = {The Hip Joint Centre can be determined to within 3 mm}, booktitle = {17th Congress of the European Society of Biomechanics}, address = {Edinburgh}, year = {2010}, language = {en} } @inproceedings{KratzensteinHellerEhrigetal.2010, author = {Kratzenstein, Stefan and Heller, Markus O. and Ehrig, Rainald and Wassilew, Georgi and Duda, Georg and Taylor, William R.}, title = {A new approach for optimally reducing skin marker artifact allows determination of the hip joint center within 3mm}, booktitle = {Transactions Vol. 35, 2010 Annual Meeting of the Orthopedic Society}, address = {New Orleans}, year = {2010}, language = {en} } @article{TaylorPoepplauKoenigetal.2011, author = {Taylor, William R. and P{\"o}pplau, Berry M. and K{\"o}nig, Christian and Ehrig, Rainald and Zachow, Stefan and Duda, Georg and Heller, Markus O.}, title = {The medial-lateral force distribution in the ovine stifle joint during walking}, volume = {29}, journal = {Journal of Orthopaedic Research}, number = {4}, doi = {10.1002/jor.21254}, pages = {567 -- 571}, year = {2011}, language = {en} } @article{BoethDudaHelleretal.2013, author = {Boeth, Heide and Duda, Georg and Heller, Markus O. and Ehrig, Rainald and Doyscher, Ralf and Jung, Tobias and Moewis, Philippe and Scheffler, Sven and Taylor, William R.}, title = {Anterior cruciate ligament-deficient patients with passive knee joint laxity have a decreased range of anterior-posterior motion during active movements}, volume = {41}, journal = {The American Journal of Sports Medicine}, number = {5}, doi = {10.1177/0363546513480465}, pages = {1051 -- 7}, year = {2013}, language = {en} } @inproceedings{TaylorKornaropoulosEhrigetal.2009, author = {Taylor, William R. and Kornaropoulos, Evgenios I. and Ehrig, Rainald and Heller, Markus O. and Duda, Georg}, title = {Reproducibility of a functional approach to gait analysis}, booktitle = {Annual meeting of the ESMAC 2009}, address = {London}, year = {2009}, language = {en} } @inproceedings{TaylorFroehlichButtgereitetal.2012, author = {Taylor, William R. and Fr{\"o}hlich, Annika and Buttgereit, Frank and Ehrig, Rainald and Witaschek, Tom and Duda, Georg}, title = {Metacarpophalangeal joint stiffness is reduced in patients affected by rheumatoid arthritis after glucocorticoid medication}, booktitle = {Proceedings of the ESM-2012, Aalborg}, editor = {Kersting, Uwe and Morlock, Michael and Jirova-Enzmann, Daniela and Dremstrup, Kim}, publisher = {Department of Health Science and Technology, Aalborg University}, pages = {39}, year = {2012}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Heller, Markus O.}, title = {Frontal plane lower limb alignment using functionally determined joint centers and axes}, booktitle = {International Conference on Computational Bioengineering}, year = {2009}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Heller, Markus O.}, title = {An imageless method to quantify the Mechanical Femoral-Tibial Angle (MFTA) using functionally defined joint centers and axes.}, booktitle = {6th Annual meeting of the German Society for Biomechanics (DGfB)}, year = {2009}, language = {en} } @article{BoethDudaHinzmannetal.2015, author = {Boeth, Heide and Duda, Georg and Hinzmann, Daniel and Hermann, Sandra and Taylor, William R. and Ehrig, Rainald and Witaschek, Tom and Buttgereit, Frank}, title = {A Novel Approach to Quantify Morning Stiffness in Patients with Rheumatoid Arthritis}, journal = {Annual European Congress of Rheumatology, EULAR 2015, Rome}, year = {2015}, language = {en} } @inproceedings{BoethDudaHinzmannetal.2015, author = {Boeth, Heide and Duda, Georg and Hinzmann, Daniel and Taylor, William R. and Ehrig, Rainald and Witaschek, Tom and Buttgereit, Frank}, title = {Objektive Quantifizierung der Morgensteifigkeit als Parameter f{\"u}r rheumatoide Arthritis im Metacarpophalangealgelenk}, booktitle = {9. Jahrestagung der Deutschen Gesellschaft f{\"u}r Biomechanik (DGfB), Bonn}, year = {2015}, language = {de} } @article{BoethBiesenHollnageletal.2021, author = {Boeth, Heide and Biesen, Robert and Hollnagel, Jeremias and Herrmann, Sandra and Ehrig, Rainald and Pelli, Lorenzo and Taylor, William R. and Duda, Georg and Buttgereit, Frank}, title = {Quantification of morning stiffness to assess disease activity and treatment effects in rheumatoid arthritis}, volume = {60}, journal = {Rheumatology}, number = {11}, doi = {10.1093/rheumatology/keab323}, pages = {5282 -- 5291}, year = {2021}, abstract = {Objectives The clinical parameter "morning stiffness" is widely used to assess the status of rheumatoid arthritis (RA), but its accurate quantitative assessment in a clinical setting has not yet been successful. This lack of individual quantification limits both personalized medication and efficacy evaluation in the treatment of RA. Methods We have developed a novel technology to assess passive resistance of the metacarpophalangeal (MCP) III joint (stiffness) and its Passive Range of Motion (PRoM). Within this pilot study, nineteen female postmenopausal RA patients and nine healthy controls were examined in the evening as well as in the morning of the following day. To verify the specificity of the biomechanical quantification, eleven patients with RA were assessed both prior to and ∼3 h after glucocorticoid therapy. Results While the healthy controls showed only minor changes between afternoon and morning, in RA patients mean±SD PRoM decreased significantly by 18 ± 22\% and stiffness increased significantly by 20 ± 18\% in the morning compared with the previous afternoon. We found a significant positive correlation between RA activity and biomechanical measures. Glucocorticoids significantly increased mean PRoM by 16 ± 11\% and reduced mean stiffness by 23 ± 22\%. Conclusion This technology allowed mechanical stiffness to be quantified in MCP joints, and has demonstrated high sensitivity in respect to disease status as well as medication effect in RA patients. Such non-invasive, low risk, and rapid assessment of biomechanical joint stiffness opens a novel avenue for judging therapy efficacy in patients with RA, and potentially also in other non-RA inflammatory joint diseases.}, language = {en} } @article{TrepczynskiKneifelHeylandetal.2024, author = {Trepczynski, Adam and Kneifel, Paul and Heyland, Mark and Leskovar, Marko and Moewis, Philippe and Damm, Philipp and Taylor, William R. and Zachow, Stefan and Duda, Georg}, title = {Impact of the External Knee Flexion Moment on Patello-Femoral Loading Derived from in vivo Loads and Kinematics}, volume = {12}, journal = {Frontiers in Bioengineering and Biotechnology}, doi = {10.3389/fbioe.2024.1473951}, year = {2024}, abstract = {Anterior knee pain and other patello-femoral (PF) complications frequently limit the success of total knee arthroplasty as the final treatment of end stage osteoarthritis. However, knowledge about the invivo loading conditions at the PF joint remains limited, as no direct measurements are available. We hypothesised that the external knee flexion moment (EFM) is highly predictive of the PF contact forces during activities with substantial flexion of the loaded knee.Six patients (65-80 years, 67-101 kg) with total knee arthroplasty (TKA) performed two activities of daily living: sit-stand-sit and squat. Tibio-femoral (TF) contact forces were measured in vivo using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The relationship between the EFM and the PF contact force was quantified using linear regression.Mean peak TF contact forces of 1.97 to 3.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). The peak EFM ranged from 3.2 to 5.9 \%BW times body height, and was a good predictor of the PF contact force (R^2 = 0.95 and 0.88 for sit-standsit and squat, respectively).The novel combination of in vivo TF contact forces and internal patellar kinematics enabled a reliable assessment of PF contact forces. The results of the regression analysis suggest that PF forces can be estimated based solely on the EFM from quantitative gait analysis. Our study also demonstrates the relevance of PF contact forces, which reach magnitudes similar to TF forces during activities of daily living.}, language = {en} }