@inproceedings{TaylorKassiSchwarzkopfetal.2005, author = {Taylor, William R. and Kassi, J.-P. and Schwarzkopf, J. and Ehrig, Rainald and Schell, H. and Duda, G.}, title = {The Profile of Mechanical Loading is Independent of Fracture Fixation Principle}, booktitle = {Proceedings of the 51th Annual Meeting of the Orthopedic Society}, address = {Washington}, year = {2005}, language = {en} } @article{TaylorPoepplauKoenigetal.2011, author = {Taylor, William R. and P{\"o}pplau, Berry M. and K{\"o}nig, Christian and Ehrig, Rainald and Zachow, Stefan and Duda, Georg and Heller, Markus O.}, title = {The medial-lateral force distribution in the ovine stifle joint during walking}, volume = {29}, journal = {Journal of Orthopaedic Research}, number = {4}, doi = {10.1002/jor.21254}, pages = {567 -- 571}, year = {2011}, language = {en} } @article{BoethDudaHelleretal.2013, author = {Boeth, Heide and Duda, Georg and Heller, Markus O. and Ehrig, Rainald and Doyscher, Ralf and Jung, Tobias and Moewis, Philippe and Scheffler, Sven and Taylor, William R.}, title = {Anterior cruciate ligament-deficient patients with passive knee joint laxity have a decreased range of anterior-posterior motion during active movements}, volume = {41}, journal = {The American Journal of Sports Medicine}, number = {5}, doi = {10.1177/0363546513480465}, pages = {1051 -- 7}, year = {2013}, language = {en} } @inproceedings{TaylorEhrigDudaetal.2006, author = {Taylor, William R. and Ehrig, Rainald and Duda, G. and Heller, Markus O.}, title = {The Symmetrical Axis of Rotation Approach (SARA) for Determination of Joint Axes in Clinical Gait Analysis}, booktitle = {1st Joint ESMAC-GCMAS Meeting, Amsterdam}, year = {2006}, language = {en} } @inproceedings{TaylorEhrigHelleretal.2004, author = {Taylor, William R. and Ehrig, Rainald and Heller, Markus O. and Schell, H. and Duda, G.}, title = {Can Skin Markers Determine the Kinematics of Underlying Bones?}, booktitle = {Proceedings of the 50th Annual Meeting of the Orthopedic Society}, address = {San Francisco}, year = {2004}, language = {en} } @article{TaylorEhrigHelleretal.2005, author = {Taylor, William R. and Ehrig, Rainald and Heller, Markus O. and Schell, H. and Klein, P. and Duda, G.}, title = {On the Influence of Soft Tissue Coverage in the Determination of Bone Kinematics using Bone Markers}, journal = {Journal of Orthopedic Research}, number = {23}, pages = {726 -- 734}, year = {2005}, language = {en} } @inproceedings{TaylorEhrigHelleretal.2005, author = {Taylor, William R. and Ehrig, Rainald and Heller, Markus O. and Schell, H. and Seebeck, P. and Duda, G.}, title = {Animal Models for Knee Injury Frequently Underestimate the Mechanical Conditions of the Clinical Situation}, booktitle = {Proceedings of the 51th Annual Meeting of the Orthopedic Society}, address = {Washington}, year = {2005}, language = {en} } @article{TaylorEhrigHelleretal.2006, author = {Taylor, William R. and Ehrig, Rainald and Heller, Markus O. and Schell, H. and Seebeck, P. and Duda, G.}, title = {Tibio-femoral Joint Contact Forces in Sheep}, journal = {Journal of Biomechanics}, number = {39}, pages = {791 -- 798}, year = {2006}, language = {en} } @inproceedings{TaylorKornaropoulosEhrigetal.2009, author = {Taylor, William R. and Kornaropoulos, Evgenios I. and Ehrig, Rainald and Heller, Markus O. and Duda, Georg}, title = {Reproducibility of a functional approach to gait analysis}, booktitle = {Annual meeting of the ESMAC 2009}, address = {London}, year = {2009}, language = {en} } @inproceedings{TaylorKratzensteinKornaropoulosetal.2009, author = {Taylor, William R. and Kratzenstein, Stefan and Kornaropoulos, Evgenios I. and Ehrig, Rainald and Moewis, Philippe and Heller, Markus O.}, title = {Non-invasive Assessment of Skeletal Kinematics}, booktitle = {Measurement and Sensing in Medicine and Health}, address = {London}, year = {2009}, language = {en} } @inproceedings{TaylorKornaropoulosKratzensteinetal.2011, author = {Taylor, William R. and Kornaropoulos, Evgenios I. and Kratzenstein, Stefan and Ehrig, Rainald and Plank, F. and Heller, Markus O.}, title = {Targeted Marker Placement for the Functional Identification of the Hip Joint Centre}, booktitle = {Transactions Vol. 36, 2011 Annual Meeting of the Orthopedic Society}, address = {Long Beach}, year = {2011}, language = {en} } @inproceedings{TaylorKoenigSpeirsetal.2006, author = {Taylor, William R. and K{\"o}nig, Christian and Speirs, A. and Ehrig, Rainald and Duda, G. and Heller, Markus O.}, title = {The medio-lateral force distribution in the sheep knee during walking}, booktitle = {5. World Congress of Biomechanics, Munich, Journal of Biomechanics}, number = {39, Suppl. 1}, pages = {S491}, year = {2006}, language = {en} } @inproceedings{TaylorKoenigSpeirsetal.2006, author = {Taylor, William R. and K{\"o}nig, Christian and Speirs, A. and Ehrig, Rainald and Duda, G. and Heller, Markus O.}, title = {Die medio-laterale Kraftverteilung im Schafsknie}, booktitle = {Deutscher Kongress f{\"u}r Orthp{\"a}die und Unfallchirurgie, Berlin}, year = {2006}, language = {en} } @article{KratzensteinKornaropoulosEhrigetal.2012, author = {Kratzenstein, Stefan and Kornaropoulos, Evgenios I. and Ehrig, Rainald and Heller, Markus O. and P{\"o}pplau, Berry M. and Taylor, William R.}, title = {Effective marker placement for functional identification of the centre of rotation at the hip}, volume = {36}, journal = {Gait \& Posture}, number = {3}, doi = {http://dx.doi.org/10.1016/j.gaitpost.2012.04.011}, pages = {482 -- 486}, year = {2012}, language = {en} } @inproceedings{TaylorFroehlichButtgereitetal.2012, author = {Taylor, William R. and Fr{\"o}hlich, Annika and Buttgereit, Frank and Ehrig, Rainald and Witaschek, Tom and Duda, Georg}, title = {Metacarpophalangeal joint stiffness is reduced in patients affected by rheumatoid arthritis after glucocorticoid medication}, booktitle = {Proceedings of the ESM-2012, Aalborg}, editor = {Kersting, Uwe and Morlock, Michael and Jirova-Enzmann, Daniela and Dremstrup, Kim}, publisher = {Department of Health Science and Technology, Aalborg University}, pages = {39}, year = {2012}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Heller, Markus O.}, title = {Frontal plane lower limb alignment using functionally determined joint centers and axes}, booktitle = {International Conference on Computational Bioengineering}, year = {2009}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Heller, Markus O.}, title = {An imageless method to quantify the Mechanical Femoral-Tibial Angle (MFTA) using functionally defined joint centers and axes.}, booktitle = {6th Annual meeting of the German Society for Biomechanics (DGfB)}, year = {2009}, language = {en} } @article{TrepczynskiKneifelHeylandetal.2025, author = {Trepczynski, Adam and Kneifel, Paul and Heyland, Mark and Leskovar, Marko and Moewis, Philippe and Damm, Philipp and Taylor, William R. and Zachow, Stefan and Duda, Georg N.}, title = {Impact of the external knee flexion moment on patello-femoral loading derived from in vivo loads and kinematics}, volume = {12/2024}, journal = {Frontiers in Bioengineering and Biotechnology}, publisher = {Frontiers Media SA}, organization = {Charit{\´e} - Universit{\"a}tsmedizin Berlin}, issn = {2296-4185}, doi = {10.3389/fbioe.2024.1473951}, year = {2025}, abstract = {Introduction: Anterior knee pain and other patello-femoral (PF) complications frequently limit the success of total knee arthroplasty as the final treatment of end stage osteoarthritis. However, knowledge about the in-vivo loading conditions at the PF joint remains limited, as no direct measurements are available. We hypothesised that the external knee flexion moment (EFM) is highly predictive of the PF contact forces during activities with substantial flexion of the loaded knee. Materials and methods: Six patients (65-80 years, 67-101 kg) with total knee arthroplasty (TKA) performed two activities of daily living: sit-stand-sit and squat. Tibio-femoral (TF) contact forces were measured in vivo using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The relationship between the EFM and the PF contact force was quantified using linear regression. Results: Mean peak TF contact forces of 1.97-3.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). The peak EFM ranged from 3.2 to 5.9 \%BW times body height, and was a good predictor of the PF contact force (R2 = 0.95 and 0.88 for sit-stand-sit and squat, respectively). Discussion: The novel combination of in vivo TF contact forces and internal patellar kinematics enabled a reliable assessment of PF contact forces. The results of the regression analysis suggest that PF forces can be estimated based solely on the EFM from quantitative gait analysis. Our study also demonstrates the relevance of PF contact forces, which reach magnitudes similar to TF forces during activities of daily living.}, language = {en} } @article{HellerMatziolisKoenigetal.2007, author = {Heller, Markus O. and Matziolis, Georg and K{\"o}nig, Christian and Taylor, William R. and Hinterwimmer, S. and Graichen, H. and Hege, Hans-Christian and Bergmann, G. and Perka, Carsten and Duda, G. N.}, title = {Muskuloskelettale Biomechanik des Kniegelenks - Grundlagen f{\"u}r die pr{\"a}operative Planung von Umstellung und Gelenkersatz}, volume = {36}, journal = {Der Orthop{\"a}de}, number = {7}, doi = {10.1007/s00132-007-1115-2}, pages = {628 -- 634}, year = {2007}, language = {en} } @article{BoethDudaHinzmannetal.2015, author = {Boeth, Heide and Duda, Georg and Hinzmann, Daniel and Hermann, Sandra and Taylor, William R. and Ehrig, Rainald and Witaschek, Tom and Buttgereit, Frank}, title = {A Novel Approach to Quantify Morning Stiffness in Patients with Rheumatoid Arthritis}, journal = {Annual European Congress of Rheumatology, EULAR 2015, Rome}, year = {2015}, language = {en} } @inproceedings{BoethDudaHinzmannetal.2015, author = {Boeth, Heide and Duda, Georg and Hinzmann, Daniel and Taylor, William R. and Ehrig, Rainald and Witaschek, Tom and Buttgereit, Frank}, title = {Objektive Quantifizierung der Morgensteifigkeit als Parameter f{\"u}r rheumatoide Arthritis im Metacarpophalangealgelenk}, booktitle = {9. Jahrestagung der Deutschen Gesellschaft f{\"u}r Biomechanik (DGfB), Bonn}, year = {2015}, language = {de} } @article{BoethBiesenHollnageletal.2021, author = {Boeth, Heide and Biesen, Robert and Hollnagel, Jeremias and Herrmann, Sandra and Ehrig, Rainald and Pelli, Lorenzo and Taylor, William R. and Duda, Georg and Buttgereit, Frank}, title = {Quantification of morning stiffness to assess disease activity and treatment effects in rheumatoid arthritis}, volume = {60}, journal = {Rheumatology}, number = {11}, doi = {10.1093/rheumatology/keab323}, pages = {5282 -- 5291}, year = {2021}, abstract = {Objectives The clinical parameter "morning stiffness" is widely used to assess the status of rheumatoid arthritis (RA), but its accurate quantitative assessment in a clinical setting has not yet been successful. This lack of individual quantification limits both personalized medication and efficacy evaluation in the treatment of RA. Methods We have developed a novel technology to assess passive resistance of the metacarpophalangeal (MCP) III joint (stiffness) and its Passive Range of Motion (PRoM). Within this pilot study, nineteen female postmenopausal RA patients and nine healthy controls were examined in the evening as well as in the morning of the following day. To verify the specificity of the biomechanical quantification, eleven patients with RA were assessed both prior to and ∼3 h after glucocorticoid therapy. Results While the healthy controls showed only minor changes between afternoon and morning, in RA patients mean±SD PRoM decreased significantly by 18 ± 22\% and stiffness increased significantly by 20 ± 18\% in the morning compared with the previous afternoon. We found a significant positive correlation between RA activity and biomechanical measures. Glucocorticoids significantly increased mean PRoM by 16 ± 11\% and reduced mean stiffness by 23 ± 22\%. Conclusion This technology allowed mechanical stiffness to be quantified in MCP joints, and has demonstrated high sensitivity in respect to disease status as well as medication effect in RA patients. Such non-invasive, low risk, and rapid assessment of biomechanical joint stiffness opens a novel avenue for judging therapy efficacy in patients with RA, and potentially also in other non-RA inflammatory joint diseases.}, language = {en} } @article{TrepczynskiKneifelHeylandetal.2024, author = {Trepczynski, Adam and Kneifel, Paul and Heyland, Mark and Leskovar, Marko and Moewis, Philippe and Damm, Philipp and Taylor, William R. and Zachow, Stefan and Duda, Georg}, title = {Impact of the External Knee Flexion Moment on Patello-Femoral Loading Derived from in vivo Loads and Kinematics}, volume = {12}, journal = {Frontiers in Bioengineering and Biotechnology}, doi = {10.3389/fbioe.2024.1473951}, year = {2024}, abstract = {Anterior knee pain and other patello-femoral (PF) complications frequently limit the success of total knee arthroplasty as the final treatment of end stage osteoarthritis. However, knowledge about the invivo loading conditions at the PF joint remains limited, as no direct measurements are available. We hypothesised that the external knee flexion moment (EFM) is highly predictive of the PF contact forces during activities with substantial flexion of the loaded knee.Six patients (65-80 years, 67-101 kg) with total knee arthroplasty (TKA) performed two activities of daily living: sit-stand-sit and squat. Tibio-femoral (TF) contact forces were measured in vivo using instrumented tibial components, while synchronously internal TF and PF kinematics were captured with mobile fluoroscopy. The measurements were used to compute PF contact forces using patient specific musculoskeletal models. The relationship between the EFM and the PF contact force was quantified using linear regression.Mean peak TF contact forces of 1.97 to 3.24 times body weight (BW) were found while peak PF forces reached 1.75 to 3.29 times body weight (BW). The peak EFM ranged from 3.2 to 5.9 \%BW times body height, and was a good predictor of the PF contact force (R^2 = 0.95 and 0.88 for sit-standsit and squat, respectively).The novel combination of in vivo TF contact forces and internal patellar kinematics enabled a reliable assessment of PF contact forces. The results of the regression analysis suggest that PF forces can be estimated based solely on the EFM from quantitative gait analysis. Our study also demonstrates the relevance of PF contact forces, which reach magnitudes similar to TF forces during activities of daily living.}, language = {en} }