@misc{IlgenfritzKerlerMuellerPreusskeretal.2005, author = {Ilgenfritz, Ernst-Michael and Kerler, Werner and M{\"u}ller-Preussker, Michael and Sternbeck, Andre and St{\"u}ben, Hinnerk}, title = {Probing the Aoki phase with N_f=2 Wilson fermions at finite temperature}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-8812}, number = {05-48}, year = {2005}, abstract = {In this letter we report on a numerical investigation of the Aoki phase in the case of finite temperature which continues our former study at zero temperature. We have performed simulations with Wilson fermions at \$\beta=4.6\$ using lattices with temporal extension \$N_{\tau}=4\$. In contrast to the zero temperature case, the existence of an Aoki phase can be confirmed for a small range in \$\kappa\$ at \$\beta=4.6\$, however, shifted slightly to lower \$\kappa\$. Despite fine-tuning \$\kappa\$ we could not separate the thermal transition line from the Aoki phase.}, language = {en} } @misc{IlgenfritzKerlerMuellerPreusskeretal.2003, author = {Ilgenfritz, Ernst-Michael and Kerler, Werner and M{\"u}ller-Preussker, Michael and Sternbeck, Andr{\´e} and St{\"u}ben, Hinnerk}, title = {A numerical reinvestigation of the Aoki phase with \$N_f=2\$ Wilson fermions at zero temperature}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-7492}, number = {03-27}, year = {2003}, abstract = {We report on a numerical reinvestigation of the Aoki phase in lattice QCD with two flavors of Wilson fermions where the parity-flavor symmetry is spontaneously broken. For this purpose the Hybrid Monte Carlo algorithm was used and an explicit symmetry-breaking source term \$h\bar{\psi} i \gamma_{5} \tau^{3}\psi\$ was added to the Wilson fermion action. The order parameter \$\langle\bar{\psi}i\gamma_{5}\tau^{3}\psi\rangle\$ was studied at several values of \$(\beta,\kappa,h)\$ on lattices of sizes \$4^4\$ to \$12^4\$. Our largest lattices can be considered as infintely large allowing to extrapolate to \$h=0\$. The existence of a parity-flavor-breaking phase can be confirmed at \$\beta=4.0\$ and \$\beta=4.3\$ while we find no sign of parity-flavor-breaking at \$\beta=4.6\$ and \$\beta=5.0\$.}, language = {en} } @misc{IlgenfritzKerlerMuellerPreusskeretal.2000, author = {Ilgenfritz, Ernst-Michael and Kerler, Werner and M{\"u}ller-Preussker, Michael and St{\"u}ben, Hinnerk}, title = {Parallel tempering and decorrelation of topological charge in full QCD}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-5930}, number = {00-25}, year = {2000}, abstract = {The improvement of simulations of QCD with dynamical Wilson fermions by combining the Hybrid Monte Carlo algorithm with parallel tempering is studied on \$10^4\$ and \$12^4\$ lattices. As an indicator for decorrelation the topological charge is used.}, language = {en} } @misc{IlgenfritzKerlerMuellerPreusskeretal.2001, author = {Ilgenfritz, Ernst-Michael and Kerler, Werner and M{\"u}ller-Preussker, Michael and St{\"u}ben, Hinnerk}, title = {Parallel tempering in full QCD with Wilson fermions}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-6593}, number = {01-33}, year = {2001}, abstract = {We study the performance of QCD simulations with dynamical Wilson fermions by combining the Hybrid Monte Carlo algorithm with parallel tempering on \$10^4\$ and \$12^4\$ lattices. In order to compare tempered with standard simulations, covariance matrices between sub-ensembles have to be formulated and evaluated using the general properties of autocorrelations of the parallel tempering algorithm. We find that rendering the hopping parameter \$\kappa\$ dynamical does not lead to an essential improvement. We point out possible reasons for this observation and discuss more suitable ways of applying parallel tempering to QCD.}, language = {en} } @article{MuellerYanWulkow1997, author = {M{\"u}ller, A. and Yan, D. and Wulkow, Michael}, title = {Molecular Parameters of Hyperbranched Polymers Made by Self-condensing Vinyl Polymerization, 1. Molecular weight distribution}, volume = {30}, journal = {Macromolecules}, pages = {7015}, year = {1997}, language = {en} } @inproceedings{KornaropoulosTaylorDudaetal.2009, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Matziolis, Georg and M{\"u}ller, Michael and Wassilew, Georgi and Asbach, Patrick and Perka, Carsten and Heller, Markus O.}, title = {An imageless method to quantify the mechanical femoral-tibial angle based on the functional determination of joint centers and axes}, booktitle = {Annual meeting of the ESMAC 2009}, address = {London}, year = {2009}, language = {en} } @article{KornaropoulosTaylorDudaetal.2010, author = {Kornaropoulos, Evgenios I. and Taylor, William R. and Duda, Georg and Ehrig, Rainald and Matziolis, Georg and M{\"u}ller, Michael and Wassilew, Georgi and Asbach, Patrick and Perka, Carsten and Heller, Markus O.}, title = {Frontal plane alignment: An imageless method to predict the mechanical femoral-tibial angle (mFTA) based on functional determination of joint centres and axes}, volume = {31}, journal = {Gait \& Posture}, number = {2}, doi = {10.1016/j.gaitpost.2009.10.006}, pages = {204 -- 208}, year = {2010}, language = {en} } @article{BuschMuellerWulkow2003, author = {Busch, Markus and M{\"u}ller, M. and Wulkow, Michael}, title = {The use of Simulation Techniques in Developing Kinetic Models for Polymerizations}, volume = {26}, journal = {Chem. Eng. Technol.}, pages = {1031}, year = {2003}, language = {en} } @article{SchradeTroegerEldashanetal.2018, author = {Schrade, Katharina and Tr{\"o}ger, Jessica and Eldashan, Adeep and Z{\"u}hlke, Kerstin and Abdul Azees, Kamal R. and Elkins, Jonathan M. and Neuenschwander, Martin and Oder, Andreas and Elkewedi, Mohamed and Jaksch, Sarah and Andrae, Karsten and Li, Jinliang and Fernandes, Jaoa and M{\"u}ller, Paul Markus and Grunwald, Stephan and Marino, Stephen F. and Vukicevic, Tanja and Eichhorst, Jenny and Wiesner, Burkhard and Weber, Marcus and Kapiloff, Michael and Rocks, Oliver and Daumke, Oliver and Wieland, Thomas and Knapp, Stefan and von Kries, Jens Peter and Klussmann, Enno}, title = {An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells}, volume = {13}, journal = {PLOS ONE}, number = {1}, doi = {10.1371/journal.pone.0191423}, pages = {e0191423 -- e0191423}, year = {2018}, abstract = {Stimulation of renal collecting duct principal cells with antidiuretic hormone (arginine-vasopressin, AVP) results in inhibition of the small GTPase RhoA and the enrichment of the water channel aquaporin-2 (AQP2) in the plasma membrane. The membrane insertion facilitates water reabsorption from primary urine and fine-tuning of body water homeostasis. Rho guanine nucleotide exchange factors (GEFs) interact with RhoA, catalyze the exchange of GDP for GTP and thereby activate the GTPase. However, GEFs involved in the control of AQP2 in renal principal cells are unknown. The A-kinase anchoring protein, AKAP-Lbc, possesses GEF activity, specifically activates RhoA, and is expressed in primary renal inner medullary collecting duct principal (IMCD) cells. Through screening of 18,431 small molecules and synthesis of a focused library around one of the hits, we identified an inhibitor of the interaction of AKAP-Lbc and RhoA. This molecule, Scaff10-8, bound to RhoA, inhibited the AKAP-Lbc-mediated RhoA activation but did not interfere with RhoA activation through other GEFs or activities of other members of the Rho family of small GTPases, Rac1 and Cdc42. Scaff10-8 promoted the redistribution of AQP2 from intracellular vesicles to the periphery of IMCD cells. Thus, our data demonstrate an involvement of AKAP-Lbc-mediated RhoA activation in the control of AQP2 trafficking.}, language = {en} } @misc{GleixnerBastubbeEifleretal.2018, author = {Gleixner, Ambros and Bastubbe, Michael and Eifler, Leon and Gally, Tristan and Gamrath, Gerald and Gottwald, Robert Lion and Hendel, Gregor and Hojny, Christopher and Koch, Thorsten and L{\"u}bbecke, Marco and Maher, Stephen J. and Miltenberger, Matthias and M{\"u}ller, Benjamin and Pfetsch, Marc and Puchert, Christian and Rehfeldt, Daniel and Schl{\"o}sser, Franziska and Schubert, Christoph and Serrano, Felipe and Shinano, Yuji and Viernickel, Jan Merlin and Walter, Matthias and Wegscheider, Fabian and Witt, Jonas T. and Witzig, Jakob}, title = {The SCIP Optimization Suite 6.0}, issn = {1438-0064}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-69361}, year = {2018}, abstract = {The SCIP Optimization Suite provides a collection of software packages for mathematical optimization centered around the constraint integer programming framework SCIP. This paper discusses enhancements and extensions contained in version 6.0 of the SCIP Optimization Suite. Besides performance improvements of the MIP and MINLP core achieved by new primal heuristics and a new selection criterion for cutting planes, one focus of this release are decomposition algorithms. Both SCIP and the automatic decomposition solver GCG now include advanced functionality for performing Benders' decomposition in a generic framework. GCG's detection loop for structured matrices and the coordination of pricing routines for Dantzig-Wolfe decomposition has been significantly revised for greater flexibility. Two SCIP extensions have been added to solve the recursive circle packing problem by a problem-specific column generation scheme and to demonstrate the use of the new Benders' framework for stochastic capacitated facility location. Last, not least, the report presents updates and additions to the other components and extensions of the SCIP Optimization Suite: the LP solver SoPlex, the modeling language Zimpl, the parallelization framework UG, the Steiner tree solver SCIP-Jack, and the mixed-integer semidefinite programming solver SCIP-SDP.}, language = {en} }