@article{AkemiForcrandFujisakietal.1992, author = {Akemi, K. and Forcrand, Ph. de and Fujisaki, M. and Hashimoto, T. and Hege, Hans-Christian and Hioki, S. and Makino, J. and Miyamura, O. and Nakamura, A. and Okuda, M. and Stamatescu, I. O. and Tago, Yoshio and Takaishi, T.}, title = {QCD on the Highly Parallel Computer AP 1000}, series = {Nucl. Phys. B Proc. Suppl. 26}, journal = {Nucl. Phys. B Proc. Suppl. 26}, doi = {10.1016/0920-5632(92)90358-Y}, pages = {644 -- 646}, year = {1992}, language = {en} } @inproceedings{HegeHutanuKaehleretal.2003, author = {Hege, Hans-Christian and Hutanu, Andrei and K{\"a}hler, Ralf and Merzky, Andr{\´e} and Radke, Thomas and Seidel, Edward and Ullmer, Brygg}, title = {Progressive Retrieval and Hierarchical Visualization of Large Remote Data}, series = {Proceedings of the 2003 Workshop on Adaptive Grid Middleware}, booktitle = {Proceedings of the 2003 Workshop on Adaptive Grid Middleware}, pages = {60 -- 72}, year = {2003}, language = {en} } @misc{GuentherKuhnHegeetal., author = {G{\"u}nther, Tobias and Kuhn, Alexander and Hege, Hans-Christian and Gross, Markus and Theisel, Holger}, title = {Progressive Monte-Carlo Rendering of Atmospheric Flow Features Across Scales}, series = {69th Annual Meeting of the APS Division of Fluid Dynamics, Gallery of Fluid Motion, Nov 20-22, 2016, Portland, OR, USA.}, journal = {69th Annual Meeting of the APS Division of Fluid Dynamics, Gallery of Fluid Motion, Nov 20-22, 2016, Portland, OR, USA.}, doi = {10.1103/APS.DFD.2016.GFM.P0030}, abstract = {To improve existing weather prediction and reanalysis capabilities, high-resolution and multi-modal climate data becomes an increasingly important topic. The advent of increasingly dense numerical simulation of atmospheric phenomena, provides new means to better understand dynamic processes and to visualize structural flow patterns that remain hidden otherwise. In the presented illustrations we demonstrate an advanced technique to visualize multiple scales of dense flow fields and Lagrangian patterns therein, simulated by state-of-the-art simulation models for each scale. They provide a deeper insight into the structural differences and patterns that occur on each scale and highlight the complexity of flow phenomena in our atmosphere.}, language = {en} } @article{GuentherKuhnHegeetal., author = {G{\"u}nther, Tobias and Kuhn, Alexander and Hege, Hans-Christian and Gross, Markus and Theisel, Holger}, title = {Progressive Monte Carlo rendering of atmospheric flow features across scales}, series = {Physical Review Fluids}, volume = {2}, journal = {Physical Review Fluids}, doi = {10.1103/PhysRevFluids.2.090502}, pages = {09050-1 -- 09050-3}, abstract = {To improve existing weather prediction and reanalysis capabilities, high-resolution and multi-modal climate data becomes an increasingly important topic. The advent of increasingly dense numerical simulation of atmospheric phenomena, provides new means to better understand dynamic processes and to visualize structural flow patterns that remain hidden otherwise. In the presented illustrations we demonstrate an advanced technique to visualize multiple scales of dense flow fields and Lagrangian patterns therein, simulated by state-of-the-art simulation models for each scale. They provide a deeper insight into the structural differences and patterns that occur on each scale and highlight the complexity of flow phenomena in our atmosphere. This paper is associated with a poster winner of a 2016 APS/DFD Milton van Dyke Award for work presented at the DFD Gallery of Fluid Motion. The original poster is available from the Gallery of Fluid Motion, https://doi.org/10.1103/APS.DFD.2016.GFM.P0030}, language = {en} } @inproceedings{DeuflhardHegeSeebass2000, author = {Deuflhard, Peter and Hege, Hans-Christian and Seebaß, Martin}, title = {Progress Towards a Combined MRI/Hyperthermia System}, series = {Proceedings Second International Congress HIGH CARE 2000}, booktitle = {Proceedings Second International Congress HIGH CARE 2000}, address = {Bochum}, year = {2000}, language = {en} } @article{Hege1996, author = {Hege, Hans-Christian}, title = {Problems and Solutions: Product of Chebyshev Polynomials}, series = {Orthogonal Polynomials and Special Functions}, volume = {6 (2)}, journal = {Orthogonal Polynomials and Special Functions}, pages = {12}, year = {1996}, language = {en} } @article{PoethkowWeberHege2011, author = {P{\"o}thkow, Kai and Weber, Britta and Hege, Hans-Christian}, title = {Probabilistic Marching Cubes}, series = {Computer Graphics Forum}, volume = {30}, journal = {Computer Graphics Forum}, number = {3}, doi = {10.1111/j.1467-8659.2011.01942.x}, pages = {931 -- 940}, year = {2011}, language = {en} } @article{PetzPoethkowHege2012, author = {Petz, Christoph and P{\"o}thkow, Kai and Hege, Hans-Christian}, title = {Probabilistic Local Features in Uncertain Vector Fields with Spatial Correlation}, series = {Computer Graphics Forum}, volume = {31}, journal = {Computer Graphics Forum}, number = {3}, pages = {1045 -- 1054}, year = {2012}, language = {en} } @article{PoethkowHege2011, author = {P{\"o}thkow, Kai and Hege, Hans-Christian}, title = {Positional Uncertainty of Isocontours: Condition Analysis and Probabilistic Measures}, series = {IEEE Transactions on Visualization and Computer Graphics}, volume = {17}, journal = {IEEE Transactions on Visualization and Computer Graphics}, number = {10}, doi = {10.1109/TVCG.2010.247}, pages = {1393 -- 1406}, year = {2011}, language = {en} } @inproceedings{KussHegeKrofcziketal.2007, author = {Kuß, Anja and Hege, Hans-Christian and Krofczik, Sabine and B{\"o}rner, Jana}, title = {Pipeline for the creation of surface-based averaged brain atlases}, series = {Proceedings of WSCG 2007 - the 15-th International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision}, volume = {15}, booktitle = {Proceedings of WSCG 2007 - the 15-th International Conference in Central Europe on Computer Graphics, Visualization and Computer Vision}, address = {Plzen, Czech Republic}, pages = {17 -- 24}, year = {2007}, language = {en} } @article{LindowBaumHege2012, author = {Lindow, Norbert and Baum, Daniel and Hege, Hans-Christian}, title = {Perceptually Linear Parameter Variations}, series = {Computer Graphics Forum}, volume = {31}, journal = {Computer Graphics Forum}, number = {2}, doi = {10.1111/j.1467-8659.2012.03054.x target}, pages = {535 -- 544}, year = {2012}, language = {en} } @misc{WiebelVosHege, author = {Wiebel, Alexander and Vos, Frans M. and Hege, Hans-Christian}, title = {Perception-Oriented Picking of Structures in Direct Volumetric Renderings}, issn = {1438-0064}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-14343}, number = {11-45}, abstract = {Radiologists from all application areas are trained to read slice-based visualizations of 3D medical image data. Despite the numerous examples of sophisticated three-dimensional renderings, especially all variants of direct volume rendering, such methods are often considered not very useful by radiologists who prefer slice-based visualization. Just recently there have been attempts to bridge this gap between 2D and 3D renderings. These attempts include specialized techniques for volume picking that result in repositioning slices. In this paper, we present a new volume picking technique that, in contrast to previous work, does not require pre-segmented data or metadata. The positions picked by our method are solely based on the data itself, the transfer function and, most importantly, on the way the volumetric rendering is perceived by viewers. To demonstrate the usefulness of the proposed method we apply it for automatically repositioning slices in an abdominal MRI scan, a data set from a flow simulation and a number of other volumetric scalar fields. Furthermore we discuss how the method can be implemented in combination with various different volumetric rendering techniques.}, language = {en} } @inproceedings{WustNadobnyGellermannetal.1997, author = {Wust, Peter and Nadobny, Jacek and Gellermann, Johanna and Seebaß, Martin and Stalling, Detlev and Hege, Hans-Christian and Deuflhard, Peter and Felix, Roland}, title = {Patient Models and Algorithms for Hyperthermia Planning}, series = {Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology ESHO-97}, booktitle = {Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology ESHO-97}, year = {1997}, language = {en} } @inproceedings{ShiTheiselWeinkaufetal.2006, author = {Shi, Kuangyu and Theisel, Holger and Weinkauf, Tino and Hauser, Helwig and Hege, Hans-Christian and Seidel, Hans-Peter}, title = {Path line oriented topology for periodic 2D time-dependent vector fields}, series = {Proc. Eurographics / IEEE VGTC Symposium on Visualization}, booktitle = {Proc. Eurographics / IEEE VGTC Symposium on Visualization}, address = {Lisbon, Portugal}, pages = {139 -- 146}, year = {2006}, language = {en} } @inproceedings{ShiTheiselHauseretal.2009, author = {Shi, Kuangyu and Theisel, Holger and Hauser, Helwig and Weinkauf, Tino and Hege, Hans-Christian and Seidel, Hans-Peter}, title = {Path Line Attributes - an Information Visualization Approach to Analyzing the Dynamic Behavior of 3D Time-Dependent Flow Fields}, series = {Topology-Based Methods in Visualization II}, booktitle = {Topology-Based Methods in Visualization II}, publisher = {Springer}, address = {Berlin}, doi = {10.1007/978-3-540-88606-8_6}, pages = {75 -- 88}, year = {2009}, language = {en} } @inproceedings{WunderlingGrammelHege1994, author = {Wunderling, Roland and Grammel, Martin and Hege, Hans-Christian}, title = {Parallele LU-Zerlegung großer, unsymmetrischer, d{\"u}nn besetzter Matrizen bei hohen Kommunikationslatenzen}, series = {GI/ITG-Workshop, Sept.1994, Mitteilungen der Fachgruppe PARS der Gesellschaft f{\"u}r Informatik (GI)}, volume = {13}, booktitle = {GI/ITG-Workshop, Sept.1994, Mitteilungen der Fachgruppe PARS der Gesellschaft f{\"u}r Informatik (GI)}, address = {Potsdam}, pages = {191 -- 200}, year = {1994}, language = {en} } @inproceedings{ZoecklerStallingHege1996, author = {Z{\"o}ckler, Malte and Stalling, Detlev and Hege, Hans-Christian}, title = {Parallel Line Integral Convolution}, series = {Proc. First Eurographics Workshop on Parallel Graphics and Visualization}, booktitle = {Proc. First Eurographics Workshop on Parallel Graphics and Visualization}, address = {Bristol, U.K.}, doi = {10.1016/S0167-8191(97)00039-2}, pages = {111 -- 128}, year = {1996}, language = {en} } @incollection{BonneauHegeJohnsonetal.2014, author = {Bonneau, Georges-Pierre and Hege, Hans-Christian and Johnson, Chris R. and Oliveira, Manuel M. and Potter, Kristin and Rheingans, Penny and Schultz, Thomas}, title = {Overview and State-of-the-Art of Uncertainty Visualization}, series = {Scientific Visualization - Uncertainty, Multifield, Biomedical, and Scalable Visualization}, booktitle = {Scientific Visualization - Uncertainty, Multifield, Biomedical, and Scalable Visualization}, publisher = {Springer}, isbn = {978-1-4471-6496-8}, doi = {10.1007/978-1-4471-6497-5_1}, pages = {3 -- 27}, year = {2014}, abstract = {The goal of visualization is to effectively and accurately communicate data. Visualization research has often overlooked the errors and uncertainty which accompany the scientific process and describe key characteristics used to fully understand the data. The lack of these representations can be attributed, in part, to the inherent difficulty in defining, characterizing, and controlling this uncertainty, and in part, to the difficulty in including additional visual metaphors in a well designed, potent display. However, the exclusion of this information cripples the use of visualization as a decision making tool due to the fact that the display is no longer a true representation of the data. This systematic omission of uncertainty commands fundamental research within the visualization community to address, integrate, and expect uncertainty information. In this chapter, we outline sources and models of uncertainty, give an overview of the state-of-the-art, provide general guidelines, outline small exemplary applications, and finally, discuss open problems in uncertainty visualization.}, language = {en} } @article{WilliePapPerkaetal., author = {Willie, Bettina M. and Pap, Thomas and Perka, Carsten and Schmidt, Carsten Oliver and Eckstein, Felix and Arampatzis, Adamantios and Hege, Hans-Christian and Madry, Henning and Vortkamp, Andrea and Duda, Georg}, title = {OVERLOAD - Rolle der Gelenk{\"u}berlastung in der prim{\"a}ren Arthrose - Die Krankheitsprogression verstehen und vermeiden}, series = {Zeitschrift f{\"u}r Rheumatologie}, volume = {74}, journal = {Zeitschrift f{\"u}r Rheumatologie}, doi = {10.1007/s00393-014-1561-2}, pages = {618 -- 621}, abstract = {Intakte Gelenke sind eine Voraussetzung f{\"u}r das Funktionieren des Skeletts und die Mobilit{\"a}t im Lebensalltag. Ein gesunder Bewegungsapparat ist die Grundlage f{\"u}r die Funktionsf{\"a}higkeit des Herz-Kreislauf-Systems wie auch der Immunabwehr. Bewegungs- und Physiotherapie sowie verschiedene Formen der Patientenaktivit{\"a}t stellen essenzielle klinische Ans{\"a}tze in der Behandlung von neurodegenerativen Erkrankungen, Schlaganfall, Diabetes und Krebs dar. Kommt es zu degenerativen Ver{\"a}nderungen von Gelenken, bedeutet dies eine wesentliche Beeintr{\"a}chtigung der Mobilit{\"a}t. N{\"a}chtliche Schmerzen und Schlafst{\"o}rungen treten in fortgeschrittenen Stadien auf und sind besonders belastend. Arthrose wird auch als degenerative Gelenkerkrankung bezeichnet. Sie geht mit Ver{\"a}nderungen in der Struktur und Zusammensetzung des Gelenkknorpels wie auch des verkalkten Knorpels, der subchondralen Kortikalis, der subchondralen Spongiosa, des Meniskus, der Gelenkkapsel und der Synovialis einher, was schließlich zur Degeneration dieser Gewebe f{\"u}hrt, aus denen sich die Synovialgelenke zusammensetzen.}, language = {de} } @article{WilliePapPerkaetal., author = {Willie, Bettina M. and Pap, Thomas and Perka, Carsten and Schmidt, Carsten Oliver and Eckstein, Felix and Arampatzis, Adamantios and Hege, Hans-Christian and Madry, Henning and Vortkamp, Andrea and Duda, Georg}, title = {OVERLOAD of joints and its role in osteoarthritis - Towards understanding and preventing progression of primary osteoarthritis}, series = {Zeitschrift f{\"u}r Rheumatologie}, volume = {76}, journal = {Zeitschrift f{\"u}r Rheumatologie}, number = {Suppl. 1}, doi = {10.1007/s00393-014-1561-2}, pages = {1 -- 4}, abstract = {Intact joints are necessary for skeletal function and mobility in daily life. A healthy musculoskeletal system is the basis for a functional cardiovascular system as well as an intact immune system. Locomotion, physiotherapy, and various forms of patient activity are essential clinical therapies used in the treatment of neurodegeneration, stroke, diabetes, and cancer. Mobility is substantially impaired with degeneration of joints and, in advanced stages, nighttime pain and sleep disturbance are particularly cumbersome. Osteoarthritis (OA) is also known as degenerative joint disease. OA involves structural and compositional changes in the articular cartilage, as well as in the calcified cartilage, subchondral cortical bone, subchondral cancellous bone, meniscus, joint capsular tissue, and synovium; which eventually lead to degeneration of these tissues comprising synovial joints.}, language = {en} } @inproceedings{RitterProhaskaBrandetal., author = {Ritter, Zully and Prohaska, Steffen and Brand, R. and Friedmann, A. and Hege, Hans-Christian and Goebbels, J{\"u}rgen and Felsenberg, Dieter}, title = {Osteocytes number and volume in osteoporotic and in healthy bone biopsies analysed using Synchrotron CT: a pilot study}, series = {Proc. ISB 2011}, booktitle = {Proc. ISB 2011}, language = {en} } @article{HermannPohlTremblayetal., author = {Hermann, Gunter and Pohl, Vincent and Tremblay, Jean Christophe and Paulus, Beate and Hege, Hans-Christian and Schild, Axel}, title = {ORBKIT - A modular Python toolbox for cross-platform post-processing of quantum chemical wavefunction data}, series = {Journal of Computational Chemistry}, volume = {37}, journal = {Journal of Computational Chemistry}, number = {16}, doi = {10.1002/jcc.24358}, pages = {1511 -- 1520}, abstract = {ORBKIT is a toolbox for postprocessing electronic structure calculations based on a highly modular and portable Python architecture. The program allows computing a multitude of electronic properties of molecular systems on arbitrary spatial grids from the basis set representation of its electronic wave function, as well as several grid-independent properties. The required data can be extracted directly from the standard output of a large number of quantum chemistry programs. ORBKIT can be used as a standalone program to determine standard quantities, for example, the electron density, molecular orbitals, and derivatives thereof. The cornerstone of ORBKIT is its modular structure. The existing basic functions can be arranged in an individual way and can be easily extended by user-written modules to determine any other derived quantity. ORBKIT offers multiple output formats that can be processed by common visualization tools (VMD, Molden, etc.). Additionally, ORBKIT offers routines to order molecular orbitals computed at different nuclear configurations according to their electronic character and to interpolate the wavefunction between these configurations. The program is open-source under GNU-LGPLv3 license and freely available at https://github.com/orbkit/orbkit/. This article provides an overview of ORBKIT with particular focus on its capabilities and applicability, and includes several example calculations.}, language = {en} } @article{ZeilhoferHege2002, author = {Zeilhofer, Hans-Florian and Hege, Hans-Christian}, title = {Operieren im Medizin-Grid}, series = {DFN-Mitteilungen, Heft 60}, journal = {DFN-Mitteilungen, Heft 60}, pages = {19 -- 20}, year = {2002}, language = {en} } @inproceedings{KussProhaskaMeyeretal.2008, author = {Kuß, Anja and Prohaska, Steffen and Meyer, Bj{\"o}rn and Rybak, J{\"u}rgen and Hege, Hans-Christian}, title = {Ontology-Based Visualization of Hierarchical Neuroanatomical Structures}, series = {Proceedings of the Eurographics Workshop on Visual Computing for Biomedicine VCBM 2008}, booktitle = {Proceedings of the Eurographics Workshop on Visual Computing for Biomedicine VCBM 2008}, pages = {177 -- 184}, year = {2008}, language = {en} } @misc{GrammelHegeWunderling, author = {Grammel, Martin and Hege, Hans-Christian and Wunderling, Roland}, title = {On the Impact of Communication Latencies on Distributed Sparse LU Factorization.}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-1245}, number = {SC-93-28}, abstract = {Sparse LU factorization offers some potential for parallelism, but at a level of very fine granularity. However, most current distributed memory MIMD architectures have too high communication latencies for exploiting all parallelism available. To cope with this, latencies must be avoided by coarsening the granularity and by message fusion. However, both techniques limit the concurrency, thereby reducing the scalability. In this paper, an implementation of a parallel LU decomposition algorithm for linear programming bases is presented for distributed memory parallel computers with noticable communication latencies. Several design decisions due to latencies, including data distribution and load balancing techniques, are discussed. An approximate performance model is set up for the algorithm, which allows to quantify the impact of latencies on its performance. Finally, experimental results for an Intel iPSC/860 parallel computer are reported and discussed.}, language = {en} } @misc{KastenHotzNoacketal.2011, author = {Kasten, Jens and Hotz, Ingrid and Noack, Bernd and Hege, Hans-Christian}, title = {On the Extraction of Long-living Features in Unsteady Fluid Flows}, series = {Topological Methods in Data Analysis and Visualization}, journal = {Topological Methods in Data Analysis and Visualization}, editor = {Pascucci, Valerio and Tricoche, Xavier and Hagen, Hans and Tierny, Julien}, publisher = {Springer}, address = {Berlin}, isbn = {978-3-642-15013-5}, doi = {10.1007/978-3-642-15014-2_10}, pages = {115 -- 126}, year = {2011}, language = {en} } @misc{KastenHotzHege, author = {Kasten, Jens and Hotz, Ingrid and Hege, Hans-Christian}, title = {On the Elusive Concept of Lagrangian Coherent Structures}, series = {Topological Methods in Data Analysis and Visualization II}, journal = {Topological Methods in Data Analysis and Visualization II}, editor = {Peikert, Ronald and Hauser, Helwig and Carr, Hamish and Fuchs, Raphael}, publisher = {Springer}, doi = {10.1007/978-3-642-23175-9_14}, pages = {207 -- 220}, language = {en} } @inproceedings{GladilinZachowDeuflhardetal.2003, author = {Gladilin, Evgeny and Zachow, Stefan and Deuflhard, Peter and Hege, Hans-Christian}, title = {On constitutive modeling of soft tissue for the long-term prediction of cranio-maxillofacial surgery outcome}, series = {International Congress Series, CARS2003, Computer Assisted Radiology and Surgery, Proceedings of the 17th International Congress and Exhibition}, volume = {1256}, booktitle = {International Congress Series, CARS2003, Computer Assisted Radiology and Surgery, Proceedings of the 17th International Congress and Exhibition}, doi = {10.1016/S0531-5131(03)00500-4}, pages = {343 -- 348}, year = {2003}, language = {en} } @article{KainmuellerLameckerHelleretal.2013, author = {Kainm{\"u}ller, Dagmar and Lamecker, Hans and Heller, Markus O. and Weber, Britta and Hege, Hans-Christian and Zachow, Stefan}, title = {Omnidirectional Displacements for Deformable Surfaces}, series = {Medical Image Analysis}, volume = {17}, journal = {Medical Image Analysis}, number = {4}, publisher = {Elsevier}, doi = {10.1016/j.media.2012.11.006}, pages = {429 -- 441}, year = {2013}, language = {en} } @inproceedings{KuhnHege, author = {Kuhn, Alexander and Hege, Hans-Christian}, title = {Object-based visualization and evaluation of cloud-resolving simulations}, series = {Book of Abstracts, SCCS 2017 - Scaling Cascades in Complex Systems, Mar 27-29, 2017, Berlin, Germany}, booktitle = {Book of Abstracts, SCCS 2017 - Scaling Cascades in Complex Systems, Mar 27-29, 2017, Berlin, Germany}, abstract = {Recent advances in high-resolution, cloud resolving simulation models pose several challenges towards respective analysis methodologies. To enable efficient comparison and validation of such models efficient, scalable, and informative diagnostic procedures are mandatory. In this talk, an object-based evaluation scheme based on the notion of scalar field topology will be presented. The presentation will cover the application of topological clustering procedures for object identification, tracking, and the retrieval of object-based statistics. The pro-posed methodology is shown to enable an advanced in-depth evaluation and visualization of high cloud-resolving models. Using a newly developed large-scale high-resolution model (i.e., HD(CP)2 ICON), it will be demonstrated that the presented procedures are applicable to assess the model performance compared to measurements (e.g., radar, satellite) and standard operational models (COSMO) at different domains and spatial scales.}, language = {en} } @incollection{BeckDeuflhardHegeetal.1996, author = {Beck, Rudolf and Deuflhard, Peter and Hege, Hans-Christian and Seebaß, Martin and Stalling, Detlev}, title = {Numerical Algorithms and Visualization in Medical Treatment Planning}, series = {Visualization and Mathematics 1997}, booktitle = {Visualization and Mathematics 1997}, editor = {Hege, Hans-Christian and Polthier, Konrad}, publisher = {Springer, Heidelberg}, pages = {303 -- 328}, year = {1996}, language = {en} } @article{PoethkowHege2013, author = {P{\"o}thkow, Kai and Hege, Hans-Christian}, title = {Nonparametric Models for Uncertainty Visualization}, series = {Computer Graphics Forum}, volume = {32}, journal = {Computer Graphics Forum}, number = {3}, doi = {10.1111/cgf.12100 target}, pages = {131 -- 140}, year = {2013}, language = {en} } @inproceedings{HanikHegeHennemuthetal., author = {Hanik, Martin and Hege, Hans-Christian and Hennemuth, Anja and von Tycowicz, Christoph}, title = {Nonlinear Regression on Manifolds for Shape Analysis using Intrinsic B{\´e}zier Splines}, series = {Proc. Medical Image Computing and Computer Assisted Intervention (MICCAI)}, booktitle = {Proc. Medical Image Computing and Computer Assisted Intervention (MICCAI)}, publisher = {Springer International Publishing}, address = {Cham}, doi = {10.1007/978-3-030-59719-1_60}, pages = {617 -- 626}, abstract = {Intrinsic and parametric regression models are of high interest for the statistical analysis of manifold-valued data such as images and shapes. The standard linear ansatz has been generalized to geodesic regression on manifolds making it possible to analyze dependencies of random variables that spread along generalized straight lines. Nevertheless, in some scenarios, the evolution of the data cannot be modeled adequately by a geodesic. We present a framework for nonlinear regression on manifolds by considering Riemannian splines, whose segments are B{\´e}zier curves, as trajectories. Unlike variational formulations that require time-discretization, we take a constructive approach that provides efficient and exact evaluation by virtue of the generalized de Casteljau algorithm. We validate our method in experiments on the reconstruction of periodic motion of the mitral valve as well as the analysis of femoral shape changes during the course of osteoarthritis, endorsing B{\´e}zier spline regression as an effective and flexible tool for manifold-valued regression.}, language = {en} } @inproceedings{SeebassStallingHegeetal.1998, author = {Seebaß, Martin and Stalling, Detlev and Hege, Hans-Christian and Wust, Peter and Felix, Roland and Deuflhard, Peter}, title = {New Features of HyperPlan, a Hyperthermia Planning System}, series = {Proc. Hyperthermia in Clincal Oncology}, booktitle = {Proc. Hyperthermia in Clincal Oncology}, address = {Venice}, pages = {16}, year = {1998}, language = {en} } @article{ZieglerHegeDuda2005, author = {Ziegler, G{\"u}nter M. and Hege, Hans-Christian and Duda, Georg}, title = {Neue Bilder f{\"u}r die Medizin?}, series = {DFN-Mitteilungen}, volume = {13(3)}, journal = {DFN-Mitteilungen}, pages = {163 -- 167}, year = {2005}, language = {en} } @inproceedings{PetzProhaskaGoubergritsetal.2008, author = {Petz, Christoph and Prohaska, Steffen and Goubergrits, Leonid and Kertzscher, Ulrich and Hege, Hans-Christian}, title = {Near-Wall Flow Visualization in Flattened Surface Neighborhoods}, series = {Proc. Simulation and Visualization 2008}, booktitle = {Proc. Simulation and Visualization 2008}, address = {Magdeburg, Germany}, pages = {93 -- 105}, year = {2008}, language = {en} } @article{HellerMatziolisKoenigetal.2007, author = {Heller, Markus O. and Matziolis, Georg and K{\"o}nig, Christian and Taylor, William R. and Hinterwimmer, S. and Graichen, H. and Hege, Hans-Christian and Bergmann, G. and Perka, Carsten and Duda, G. N.}, title = {Muskuloskelettale Biomechanik des Kniegelenks - Grundlagen f{\"u}r die pr{\"a}operative Planung von Umstellung und Gelenkersatz}, series = {Der Orthop{\"a}de}, volume = {36}, journal = {Der Orthop{\"a}de}, number = {7}, doi = {10.1007/s00132-007-1115-2}, pages = {628 -- 634}, year = {2007}, language = {en} } @article{GoubergritsHellmeierBrueningetal., author = {Goubergrits, Leonid and Hellmeier, Florian and Bruening, Jan Joris and Spuler, Andreas and Hege, Hans-Christian and Voss, Samuel and Janiga, G{\´a}bor and Saalfeld, Sylvia and Beuing, Oliver and Berg, Philipp}, title = {Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Uncertainty Quantification of Geometric Rupture Risk Parameters}, series = {BioMedical Engineering OnLine}, volume = {18}, journal = {BioMedical Engineering OnLine}, number = {35}, doi = {10.1186/s12938-019-0657-y}, abstract = {Background Geometric parameters have been proposed for prediction of cerebral aneurysm rupture risk. Predicting the rupture risk for incidentally detected unruptured aneurysms could help clinicians in their treatment decision. However, assessment of geometric parameters depends on several factors, including the spatial resolution of the imaging modality used and the chosen reconstruction procedure. The aim of this study was to investigate the uncertainty of a variety of previously proposed geometric parameters for rupture risk assessment, caused by variability of reconstruction procedures. Materials 26 research groups provided segmentations and surface reconstructions of five cerebral aneurysms as part of the Multiple Aneurysms AnaTomy CHallenge (MATCH) 2018. 40 dimensional and non-dimensional geometric parameters, describing aneurysm size, neck size, and irregularity of aneurysm shape, were computed. The medians as well as the absolute and relative uncertainties of the parameters were calculated. Additionally, linear regression analysis was performed on the absolute uncertainties and the median parameter values. Results A large variability of relative uncertainties in the range between 3.9 and 179.8\% was found. Linear regression analysis indicates that some parameters capture similar geometric aspects. The lowest uncertainties < 6\% were found for the non-dimensional parameters isoperimetric ratio, convexity ratio, and ellipticity index. Uncertainty of 2D and 3D size parameters was significantly higher than uncertainty of 1D parameters. The most extreme uncertainties > 80\% were found for some curvature parameters. Conclusions Uncertainty analysis is essential on the road to clinical translation and use of rupture risk prediction models. Uncertainty quantification of geometric rupture risk parameters provided by this study may help support development of future rupture risk prediction models.}, language = {en} } @article{VohraHerreraTavhelidseSucketal., author = {Vohra, Sumit Kumar and Herrera, Kristian and Tavhelidse-Suck, Tinatini and Knoblich, Simon and Seleit, Ali and Boulanger-Weill, Jonathan and Chambule, Sydney and Aspiras, Ariel and Santoriello, Cristina and Randlett, Owen and Wittbrodt, Joachim and Aulehla, Alexander and Lichtman, Jeff W. and Fishman, Mark and Hege, Hans-Christian and Baum, Daniel and Engert, Florian and Isoe, Yasuko}, title = {Multi-species community platform for comparative neuroscience in teleost fish}, doi = {10.1101/2024.02.14.580400}, abstract = {Studying neural mechanisms in complementary model organisms from different ecological niches in the same animal class can leverage the comparative brain analysis at the cellular level. To advance such a direction, we developed a unified brain atlas platform and specialized tools that allowed us to quantitatively compare neural structures in two teleost larvae, medaka (Oryzias latipes) and zebrafish (Danio rerio). Leveraging this quantitative approach we found that most brain regions are similar but some subpopulations are unique in each species. Specifically, we confirmed the existence of a clear dorsal pallial region in the telencephalon in medaka lacking in zebrafish. Further, our approach allows for extraction of differentially expressed genes in both species, and for quantitative comparison of neural activity at cellular resolution. The web-based and interactive nature of this atlas platform will facilitate the teleost community's research and its easy extensibility will encourage contributions to its continuous expansion.}, language = {en} } @inproceedings{KainmuellerLameckerZachowetal.2008, author = {Kainm{\"u}ller, Dagmar and Lamecker, Hans and Zachow, Stefan and Heller, Markus O. and Hege, Hans-Christian}, title = {Multi-Object Segmentation with Coupled Deformable Models}, series = {Proc. Medical Image Understanding and Analysis}, booktitle = {Proc. Medical Image Understanding and Analysis}, pages = {34 -- 38}, year = {2008}, language = {en} } @article{HashimotoHege1993, author = {Hashimoto, T. and Hege, Hans-Christian}, title = {Monte Carlo Renormalization Study at Large beta in the Confinement Region}, series = {Nuclear Phys. B. Proc. Suppl.}, volume = {30}, journal = {Nuclear Phys. B. Proc. Suppl.}, doi = {10.1016/0920-5632(93)90263-6}, pages = {517 -- 520}, year = {1993}, language = {en} } @article{LacarellePMoeckPaschereitetal.2010, author = {Lacarelle, Arnaud and P. Moeck, Jonas and Paschereit, Christian and Gelbert, Gregor and King, Rudibert and M. Luchtenburg, Dirk and Noack, Bernd R. and Kasten, Jens and Hege, Hans-Christian}, title = {Modeling a Fuel/Air Mixing to Control the Pressure Pulsations and NOx Emissions in a Lean Premixed Combustor}, series = {Active Flow Control II}, volume = {108}, journal = {Active Flow Control II}, publisher = {Springer, Berlin}, doi = {10.1007/978-3-642-11735-0_20}, pages = {307 -- 321}, year = {2010}, language = {en} } @inproceedings{NeubertLameckerHegeetal.2007, author = {Neubert, Kerstin and Lamecker, Hans and Hege, Hans-Christian and Menzel, Randolf and Rybak, J{\"u}rgen}, title = {Model-based autosegmentation of brain structures in the honeybee using statistical shape models}, series = {Proc. 8th Int. Congr. of Neuroethology (ICN)}, booktitle = {Proc. 8th Int. Congr. of Neuroethology (ICN)}, year = {2007}, language = {en} } @inproceedings{GiehlGowinEngelkeetal.2000, author = {Giehl, Michael and Gowin, Wolfgang and Engelke, Klaus and Karolczak, Marek and Hege, Hans-Christian and Schmidt-Ehrenberg, Johannes and Felsenberg, Dieter}, title = {Micro-CT zur Darstellung kontrastgebender Strukturen im Weichteilgewebe}, series = {81. Deutscher R{\"o}ntgenkongress}, booktitle = {81. Deutscher R{\"o}ntgenkongress}, address = {Wiesbaden}, year = {2000}, language = {en} } @article{CourniaAllenAndricioaeietal.2015, author = {Cournia, Zoe and Allen, Toby W. and Andricioaei, Ioan and Antonny, Bruno and Baum, Daniel and Brannigan, Grace and Buchete, Nicolae-Viorel and Deckman, Jason T. and Delemotte, Lucie and del Val, Coral and Friedman, Ran and Gkeka, Paraskevi and Hege, Hans-Christian and H{\´e}nin, J{\´e}r{\^o}me and Kasimova, Marina A. and Kolocouris, Antonios and Klein, Michael L. and Khalid, Syma and Lemieux, Joanne and Lindow, Norbert and Roy, Mahua and Selent, Jana and Tarek, Mounir and Tofoleanu, Florentina and Vanni, Stefano and Urban, Sinisa and Wales, David J. and Smith, Jeremy C. and Bondar, Ana-Nicoleta}, title = {Membrane Protein Structure, Function and Dynamics: A Perspective from Experiments and Theory}, series = {Journal of Membrane Biology}, volume = {248}, journal = {Journal of Membrane Biology}, number = {4}, doi = {10.1007/s00232-015-9802-0}, pages = {611 -- 640}, year = {2015}, language = {en} } @inproceedings{KraemerHerrmannBoethetal., author = {Kr{\"a}mer, Martin and Herrmann, Karl-Heinz and Boeth, Heide and Tycowicz, Christoph von and K{\"o}nig, Christian and Zachow, Stefan and Ehrig, Rainald and Hege, Hans-Christian and Duda, Georg and Reichenbach, J{\"u}rgen}, title = {Measuring 3D knee dynamics using center out radial ultra-short echo time trajectories with a low cost experimental setup}, series = {ISMRM (International Society for Magnetic Resonance in Medicine), 23rd Annual Meeting 2015, Toronto, Canada}, booktitle = {ISMRM (International Society for Magnetic Resonance in Medicine), 23rd Annual Meeting 2015, Toronto, Canada}, language = {en} } @article{GuentherKuhnHegeetal., author = {G{\"u}nther, Tobias and Kuhn, Alexander and Hege, Hans-Christian and Theisel, Holger}, title = {MCFTLE: Monte Carlo Rendering of Finite-Time Lyapunov Exponent Fields}, series = {Computer Graphics Forum}, volume = {35}, journal = {Computer Graphics Forum}, number = {3}, doi = {10.1111/cgf.12914}, pages = {381 -- 390}, language = {en} } @misc{GuentherKuhnHegeetal., author = {G{\"u}nther, Tobias and Kuhn, Alexander and Hege, Hans-Christian and Theisel, Holger}, title = {MCFTLE: Monte Carlo Rendering of Finite-Time Lyapunov Exponent Fields}, issn = {1438-0064}, doi = {10.1111/cgf.12914}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-59054}, abstract = {Traditionally, Lagrangian fields such as finite-time Lyapunov exponents (FTLE) are precomputed on a discrete grid and are ray casted afterwards. This, however, introduces both grid discretization errors and sampling errors during ray marching. In this work, we apply a progressive, view-dependent Monte Carlo-based approach for the visualization of such Lagrangian fields in time-dependent flows. Our ap- proach avoids grid discretization and ray marching errors completely, is consistent, and has a low memory consumption. The system provides noisy previews that con- verge over time to an accurate high-quality visualization. Compared to traditional approaches, the proposed system avoids explicitly predefined fieldline seeding structures, and uses a Monte Carlo sampling strategy named Woodcock tracking to distribute samples along the view ray. An acceleration of this sampling strategy requires local upper bounds for the FTLE values, which we progressively acquire during the rendering. Our approach is tailored for high-quality visualizations of complex FTLE fields and is guaranteed to faithfully represent detailed ridge surface structures as indicators for Lagrangian coherent structures (LCS). We demonstrate the effectiveness of our approach by using a set of analytic test cases and real-world numerical simulations.}, language = {en} } @article{ZachowHegeDeuflhard2005, author = {Zachow, Stefan and Hege, Hans-Christian and Deuflhard, Peter}, title = {Maxillofacial surgery planning with 3D soft tissue prediction - modeling, planning, simulation}, series = {2. Int. Conf. on Advanced Digital Technology in Head and Neck Reconstruction, Abstract 33}, journal = {2. Int. Conf. on Advanced Digital Technology in Head and Neck Reconstruction, Abstract 33}, address = {Banff, Alberta, CA}, pages = {64}, year = {2005}, language = {en} } @misc{HegePolthierRumpf2001, author = {Hege, Hans-Christian and Polthier, Konrad and Rumpf, Martin}, title = {MathInsight 2002}, year = {2001}, language = {en} }