@misc{KoberSaderZeilhoferetal., author = {Kober, Cornelia and Sader, Robert and Zeilhofer, Hans-Florian and Prohaska, Steffen and Zachow, Stefan and Deuflhard, Peter}, title = {Anisotrope Materialmodellierung f{\"u}r den menschlichen Unterkiefer}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-6574}, number = {01-31}, abstract = {Im Rahmen der biomechanischen Simulation kn{\"o}cherner Organe ist die Frage nach einer befriedigenden Materialbeschreibung nach wie vor ungel{\"o}st. Computertomographische Datens{\"a}tze liefern eine r{\"a}umliche Verteilung der (R{\"o}ntgen-)Dichte und erm{\"o}glichen damit eine gute Darstellung der individuellen Geometrie. Weiter k{\"o}nnen die verschiedenen Materialbestandteile des Knochens, Spongiosa und Kortikalis, voneinander getrennt werden. Aber die richtungsab{\"a}ngige Information der Materialanisotropie ist verloren. In dieser Arbeit wird ein Ansatz f{\"u}r eine anisotrope Materialbeschreibung vorgestellt, die es erm{\"o}glicht, den Einfluss der individuellen kn{\"o}chernen Struktur auf das makroskopische Materialverhalten abzusch{\"a}tzen.}, language = {de} } @misc{ErdmannKoberLangetal., author = {Erdmann, Bodo and Kober, Cornelia and Lang, Jens and Sader, Robert and Zeilhofer, Hans-Florian and Deuflhard, Peter}, title = {Efficient and Reliable Finite Element Methods for Simulation of the Human Mandible}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-6403}, number = {01-14}, abstract = {By computed tomography data (CT), the individual geometry of the mandible is quite well reproduced, also the separation between cortical and trabecular bone. Using anatomical knowledge about the architecture and the functional potential of the masticatory muscles, realistic situations were approximated. The solution of the underlying partial differential equations describing linear elastic material behaviour is provided by an adaptive finite element method. Estimations of the discretization error, local grid refinement, and multilevel techniques guarantee the reliability and efficiency of the method.}, language = {en} } @misc{KoberErdmannSaderetal., author = {Kober, Cornelia and Erdmann, Bodo and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Simulation of the Human Mandible: Comparison of Bone Mineral Density and Stress/Strain Profiles due to Masticatory Muscles' Traction}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-7458}, number = {03-23}, abstract = {The correlation of the inner architecture of bone and its functional loading was already stated by Wolff in 1892. Our objective is to demonstrate this interdependence in the case of the human mandible. For this purpose, stress/strain profiles occuring at a human lateral bite were simulated. Additionally, by a combination of computer graphics modules, a three--dimensional volumetric visualization of bone mineral density could be given. Qualitative correspondences between the density profile of the jaw and the simulated stress/strain profiles could be pointed out. In the long run, this might enable the use of the simulation for diagnosis and prognosis. The solution of the underlying partial differential equations describing linear elastic material behaviour was provided by an adaptive finite element method. Estimates of the discretization errors, local grid refinement, and multilevel techniques guaranteed the reliability and efficiency of the method.}, language = {en} } @misc{KoberErdmannLangetal., author = {Kober, Cornelia and Erdmann, Bodo and Lang, Jens and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Adaptive Finite Element Simulation of the Human Mandible Using a New Physiological Model of the Masticatory Muscles}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-7917}, number = {04-16}, abstract = {Structural mechanics simulation of bony organs is of general medical and biomechanical interest, because of the interdependence of the inner architecture of bone and its functional loading already stated by Wolff in 1892. This work is part of a detailed research project concerning the human mandible. By adaptive finite element techniques, stress/strain profiles occurring in the bony structure under biting were simulated. Estimates of the discretization errors, local grid refinement, and multilevel techniques guarantee the reliability and efficiency of the method. In general, our simulation requires a representation of the organ's geometry, an appropriate material description, and the load case due to teeth, muscle, or joint forces. In this paper, we want to focus on the influence of the masticatory system. Our goal is to capture the physiological situation as far as possible. By means of visualization techniques developed by the group, we are able to extract individual muscle fibres from computed tomography data. By a special algorithm, the fibres are expanded to fanlike (esp. for the musc. temporalis) coherent vector fields similar to the anatomical reality. The activity of the fibres can be adapted according to compartmentalisation of the muscles as measured by electromyological experiments. A refined sensitivity analysis proved remarkable impact of the presented approach on the simulation results.}, language = {en} } @misc{KoberErdmannHellmichetal., author = {Kober, Cornelia and Erdmann, Bodo and Hellmich, Christian and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Anisotropic Simulation of the Human Mandible}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-7873}, number = {04-12}, abstract = {We focus on the role of anisotropic elasticity in the simulation of the load distribution in a human mandible due to a lateral bite on the leftmost premolar. Based on experimental evidence, we adopt ``local''" orthotropy of the elastic properties of the bone tissue. Since the trajectories of anisotropic elasticity are not accessible from Computer Tomographic (CT) data, they will be reconstructed from (i) the organ's geometry and (ii) from coherent structures which can be recognized from the spatial distribution of the CT values. A sensitivity analysis comprising various 3D FE simulations reveals the relevance of elastic anisotropy for the load carrying behavior of a human mandible: Comparison of the load distributions in isotropic and anisotropic simulations indicates that anisotropy seems to ``spare''" the mandible from loading. Moreover, a maximum degree of anisotropy leads to kind of an load minimization of the mandible, expressed by a minimum of different norms of local strain, evaluated throughout the organ. Thus, we may suggest that anisotropy is not only relevant, but also in some sense ``optimal''.}, language = {en} } @inproceedings{KoberErdmannHellmichetal.2005, author = {Kober, C. and Erdmann, Bodo and Hellmich, Christian and Geiger, M. and Sader, Robert and Zeilhofer, Hans-Florian}, title = {How does the periodontal ligament influence overall stress/strain profiles of a partially edentulous mandible?}, series = {Proc. of 8th Int. Conference on Biological Mechanisms of Tooth Eruption, Resorption and Movement, Phuket, Thailand}, booktitle = {Proc. of 8th Int. Conference on Biological Mechanisms of Tooth Eruption, Resorption and Movement, Phuket, Thailand}, editor = {Davidovitch, Z. and Mah, J. and Suthanarak, S.}, address = {Harvard Society of the Advancement of Orthodontics, Boston, Massachusetts, USA}, year = {2005}, language = {en} } @inproceedings{KoberErdmannHellmichetal.2004, author = {Kober, C. and Erdmann, Bodo and Hellmich, Christian and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Anisotropic Simulation of the Human Mandible}, series = {Proc. of 17th ASCE Engineering Mechanics Conference}, booktitle = {Proc. of 17th ASCE Engineering Mechanics Conference}, publisher = {Univ. of Delaware}, year = {2004}, language = {en} } @inproceedings{KoberErdmannHellmichetal.2005, author = {Kober, C. and Erdmann, Bodo and Hellmich, Christian and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Consideration of Bone Inhomogeneity and Anisotropy in Deformation Analysis of a Human Mandible}, series = {Proc. of BMT2005, 39th Annual Congress of the German Society of Biomedical Engineering, Nuremberg, Germany}, volume = {1}, booktitle = {Proc. of BMT2005, 39th Annual Congress of the German Society of Biomedical Engineering, Nuremberg, Germany}, editor = {Boenick, U. and Bolz, A.}, publisher = {VDE}, address = {Nuremberg, Germany}, pages = {814 -- 815}, year = {2005}, language = {en} } @inproceedings{KoberSaderZeilhoferetal.2003, author = {Kober, C. and Sader, Robert and Zeilhofer, Hans-Florian and Deuflhard, Peter}, title = {An Individual Anisotropic and Inhomogeneous Material Description of the Human Mandible}, series = {Mathematical Modelling and Computing in Biology and Medicine}, booktitle = {Mathematical Modelling and Computing in Biology and Medicine}, editor = {Capasso, Vincenzo}, publisher = {ESTMB}, pages = {103 -- 109}, year = {2003}, language = {en} } @incollection{LangErdmannKoberetal.2003, author = {Lang, Jens and Erdmann, Bodo and Kober, Cornelia and Deuflhard, Peter and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Effiziente und zuverl{\"a}ssige Finite-Elemente-Methoden zur Simulation des menschlichen Unterkiefers}, series = {Berichte des IZWR - Interdisziplin{\"a}res Zentrum f{\"u}r Wissenschaftliches Rechnen}, volume = {1}, booktitle = {Berichte des IZWR - Interdisziplin{\"a}res Zentrum f{\"u}r Wissenschaftliches Rechnen}, editor = {Alt, Walter and Hermann, Martin}, publisher = {Universit{\"a}t Jena}, address = {Germany}, pages = {49 -- 57}, year = {2003}, language = {en} } @article{KoberStuebingerErdmannetal.2006, author = {Kober, C. and St{\"u}binger, S. and Erdmann, Bodo and Hellmich, Christian and Radtke, Thomas and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Finite element simulation of the human mandible}, series = {Int. Poster J. Dent. Oral Med.}, journal = {Int. Poster J. Dent. Oral Med.}, year = {2006}, language = {en} } @article{KoberStuebingerErdmannetal.2006, author = {Kober, C. and St{\"u}binger, S. and Erdmann, Bodo and Hellmich, Christian and Radtke, Thomas and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Finite element simulation of the human mandible}, series = {Int. Poster J. Dent. Oral Med.}, journal = {Int. Poster J. Dent. Oral Med.}, year = {2006}, language = {en} } @inproceedings{KoberErdmannHellmichetal.2005, author = {Kober, C. and Erdmann, Bodo and Hellmich, Christian and Sader, Robert and Zeilhofer, Hans-Florian}, title = {The Influence of the Periodontal Ligament on Overall Stress/Strain Profiles of a Human Mandible}, series = {Proc. of 23rd CADFEM Users' Meeting, Int. Congress on FEM Technology, Biomechanics}, booktitle = {Proc. of 23rd CADFEM Users' Meeting, Int. Congress on FEM Technology, Biomechanics}, editor = {CADFEM GmbH, Grafing}, address = {Bonn, Germany}, pages = {1 -- 10}, year = {2005}, language = {en} } @article{KoberErdmannHellmichetal.2006, author = {Kober, C. and Erdmann, Bodo and Hellmich, Christian and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Consideration of anisotropic elasticity minimizes volumetric rather than shear deformation in human mandible}, series = {Comp. Meth. Biomech. Biomed. Eng.}, volume = {9(2)}, journal = {Comp. Meth. Biomech. Biomed. Eng.}, pages = {91 -- 101}, year = {2006}, language = {en} } @article{KoberErdmannHellmichetal.2006, author = {Kober, C. and Erdmann, Bodo and Hellmich, Christian and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Validation of interdependency between inner structure visualization and structural mechanics simulation}, series = {Int. Poster J. Dent. Oral Med.}, journal = {Int. Poster J. Dent. Oral Med.}, year = {2006}, language = {en} } @article{KoberErdmannHellmichetal.2006, author = {Kober, C. and Erdmann, Bodo and Hellmich, Christian and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Validation of interdependency between inner structure visualization and structural mechanics simulation}, series = {Int. Poster J. Dent. Oral Med.}, journal = {Int. Poster J. Dent. Oral Med.}, year = {2006}, language = {en} } @inproceedings{KoberErdmannLangetal.2004, author = {Kober, C. and Erdmann, Bodo and Lang, Jens and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Sensitivity of the Temporomandibular Joint Capsule for the Structural Behaviour of the Human Mandible}, series = {Proc. BMT 2004}, volume = {49-2}, booktitle = {Proc. BMT 2004}, address = {Ilmenau, Deutschland}, pages = {372 -- 373}, year = {2004}, language = {en} } @inproceedings{KoberErdmannLangetal.2004, author = {Kober, C. and Erdmann, Bodo and Lang, Jens and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Adaptive Finite Element Simulation of the Human Mandible Using a New Physiological Model of the Masticatory Muscles}, series = {Proc. of 75th Annual Meeting of the GAMM}, volume = {4}, booktitle = {Proc. of 75th Annual Meeting of the GAMM}, number = {1}, pages = {332 -- 333}, year = {2004}, language = {en} } @inproceedings{KoberErdmannSaderetal.2003, author = {Kober, C. and Erdmann, Bodo and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Simulation of the Human Mandible}, series = {Proceedings of 10th Workshop on The Finite Element Method in Biomedical Engineering, Biomechanics and Related Fields}, booktitle = {Proceedings of 10th Workshop on The Finite Element Method in Biomedical Engineering, Biomechanics and Related Fields}, address = {Ulm, Germany}, year = {2003}, language = {en} } @article{KoberErdmannSaderetal.2003, author = {Kober, C. and Erdmann, Bodo and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Belastungssimulation beim menschlichen Biss im Vergleich mit der Dichtestruktur im Unterkieferknochen}, series = {Biomedizinische Technik}, volume = {48}, journal = {Biomedizinische Technik}, number = {Erg{\"a}nzungsband 1}, pages = {268 -- 269}, year = {2003}, language = {en} } @inproceedings{KoberErdmannSaderetal.2004, author = {Kober, C. and Erdmann, Bodo and Sader, Robert and Zeilhofer, Hans-Florian}, title = {An Application of Adaptive Finite Element Techniques in Biomechanics}, series = {22. CAD-FEM Users Meeting - Internationale FEM Technologietage}, booktitle = {22. CAD-FEM Users Meeting - Internationale FEM Technologietage}, address = {Dresden, Germany}, year = {2004}, language = {en} } @article{ZeilhoferZachowFairleyetal.2000, author = {Zeilhofer, Hans-Florian and Zachow, Stefan and Fairley, Jeffrey and Sader, Robert and Deuflhard, Peter}, title = {Treatment Planning and Simulation in Craniofacial Surgery with Virtual Reality Techiques}, series = {Journal of Cranio-Maxillofacial Surgery}, volume = {28 (Suppl. 1)}, journal = {Journal of Cranio-Maxillofacial Surgery}, pages = {82}, year = {2000}, language = {en} } @inproceedings{ZachowGladilinSaderetal.2003, author = {Zachow, Stefan and Gladilin, Evgeny and Sader, Robert and Zeilhofer, Hans-Florian}, title = {Draw \& Cut: Intuitive 3D Osteotomy Planning on Polygonal Bone Models}, series = {Computer Assisted Radiology and Surgery (CARS)}, booktitle = {Computer Assisted Radiology and Surgery (CARS)}, address = {London, UK}, doi = {10.1016/S0531-5131(03)00272-3}, pages = {362 -- 369}, year = {2003}, language = {en} } @article{ZeilhoferHege2002, author = {Zeilhofer, Hans-Florian and Hege, Hans-Christian}, title = {Operieren im Medizin-Grid}, series = {DFN-Mitteilungen, Heft 60}, journal = {DFN-Mitteilungen, Heft 60}, pages = {19 -- 20}, year = {2002}, language = {en} } @inproceedings{ZeilhoferSaderApostolescuetal.2000, author = {Zeilhofer, Hans-Florian and Sader, Robert and Apostolescu, Victor and Hoffmann, Karl-Heinz and G{\"o}bel, Martin and Hege, Hans-Christian}, title = {Die Bedeutung breitbandiger und leistungsf{\"a}higer Kommunikationsinfrastrukturen f{\"u}r die kraniomaxillofaziale Chirurgie - M{\"o}glichkeiten der netzbasierten Bildverarbeitung}, series = {Bildverarbeitung f{\"u}r die Medizin 2000 (Abstract)}, booktitle = {Bildverarbeitung f{\"u}r die Medizin 2000 (Abstract)}, address = {M{\"u}nchen}, year = {2000}, language = {en} } @article{ZachowGladilinTrepczynskietal.2002, author = {Zachow, Stefan and Gladilin, Evgeny and Trepczynski, Adam and Sader, Robert and Zeilhofer, Hans-Florian}, title = {3D Osteotomy Planning in Cranio-Maxillofacial Surgery: Experiences and Results of Surgery Planning and Volumetric Finite-Element Soft Tissue Prediction in Three Clinical Cases}, series = {Computer Assisted Radiology and Surgery (CARS)}, journal = {Computer Assisted Radiology and Surgery (CARS)}, publisher = {Springer Verlag}, pages = {983 -- 987}, year = {2002}, language = {en} } @inproceedings{ZachowGladilinZeilhoferetal.2001, author = {Zachow, Stefan and Gladilin, Evgeny and Zeilhofer, Hans-Florian and Sader, Robert}, title = {Improved 3D Osteotomy Planning in Cranio-Maxillofacial Surgery}, series = {Proc. Medical Image Computing and Computer-Assisted Intervention (MICCAI 2001)}, booktitle = {Proc. Medical Image Computing and Computer-Assisted Intervention (MICCAI 2001)}, address = {Utrecht, The Netherlands}, doi = {10.1007/3-540-45468-3_57}, pages = {473 -- 481}, year = {2001}, language = {en} } @inproceedings{ZachowGladilinZeilhoferetal.2001, author = {Zachow, Stefan and Gladilin, Evgeny and Zeilhofer, Hans-Florian and Sader, Robert}, title = {3D Osteotomieplanung in der MKG-Chirurgie unter Ber{\"u}cksichtigung der r{\"a}umlichen Weichgewebeanordnung}, series = {Rechner- und sensorgest{\"u}tzte Chirurgie, GI Proc. zur SFB 414 Tagung}, booktitle = {Rechner- und sensorgest{\"u}tzte Chirurgie, GI Proc. zur SFB 414 Tagung}, address = {Heidelberg}, pages = {217 -- 226}, year = {2001}, language = {en} }