@misc{DeuflhardLouisSchlegeletal., author = {Deuflhard, Peter and Louis, Alfred and Schlegel, W. and Seebass, Martin}, title = {Workshop "Scientific Computing in der Medizin" SCMED '97}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-5474}, number = {TR-97-05}, abstract = {Die Arbeitstagung \glqq Scientific Computing in der Medizin\grqq , kurz SCMED \grq 97, findet vom 22. - 23. September 1997 im neu errichteten Geb{\"a}ude des Konrad-Zuse-Zentrums auf dem Dahlemer naturwissenschaftlichen Campus der Freien Universt{\"a}t Berlin statt.}, language = {en} } @inproceedings{SeebassStallingZoeckleretal.1997, author = {Seebaß, Martin and Stalling, Detlev and Z{\"o}ckler, Malte and Hege, Hans-Christian and Wust, Peter and Felix, Roland and Deuflhard, Peter}, title = {Surface Mesh Generation for Numerical Simulations of Hyperthermia Treatments}, series = {Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology (ESHO-97)}, booktitle = {Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology (ESHO-97)}, pages = {146}, year = {1997}, language = {en} } @inproceedings{SeebassStallingZoeckleretal.1997, author = {Seebass, Martin and Stalling, Detlev and Z{\"o}ckler, M. and Hege, Hans-Christian and Wust, Peter and Felix, Roland and Deuflhard, Peter}, title = {Surface Mesh Generation for Numerical Simulations of Hyperthermia Treatments}, series = {Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997}, booktitle = {Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997}, pages = {146}, year = {1997}, language = {en} } @inproceedings{WustNadobnyGellermannetal.1997, author = {Wust, Peter and Nadobny, Jacek and Gellermann, Johanna and Seebaß, Martin and Stalling, Detlev and Hege, Hans-Christian and Deuflhard, Peter and Felix, Roland}, title = {Patient Models and Algorithms for Hyperthermia Planning}, series = {Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology ESHO-97}, booktitle = {Proceedings of the 16th Annual Meeting of the European Society for Hyperthermic Oncology ESHO-97}, year = {1997}, language = {en} } @inproceedings{WustNadobnyGellermannetal.1997, author = {Wust, Peter and Nadobny, Johanna and Gellermann, Johanna and Seebass, Martin and Stalling, Detlev and Hege, Hans-Christian and Deuflhard, Peter and Budach, Volker and Felix, Roland}, title = {Patient Models and Algorithms for Hyperthermia Planning}, series = {Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997}, booktitle = {Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997}, pages = {75}, year = {1997}, language = {en} } @misc{ErdmannLangSeebass, author = {Erdmann, Bodo and Lang, Jens and Seebass, Martin}, title = {Optimization of Temperature Distributions for Regional Hyperthermia Based on a Nonlinear Heat Transfer Model}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-3283}, number = {SC-97-59}, abstract = {We describe an optimization process specially designed for regional hyperthermia of deap seated tumors in order to achieve desired steady--state temperature distributions. A nonlinear three--dimensional heat--transfer model based on temperature--dependent blood perfusion is applied to predict the temperature. Optimal heating is obtained by minimizing an integral object function which measures the distance between desired and model predicted temperatures. Sequential minima are calculated from successively improved constant--rate perfusion models employing a damped Newton method in an inner iteration. Numerical results for a Sigma 60 applicator are presented. This work has been supported by Deutsche Forschungsgemeinschaft (DFG) within the Sonderforschungsbereich 273 \glqq Hyperthermie: Methodik und Klinik \grqq .}, language = {en} } @inproceedings{BeckDeuflhardHegeetal.1997, author = {Beck, Rudolf and Deuflhard, Peter and Hege, Hans-Christian and Seebass, Martin and Stalling, Detlev}, title = {Numerical Algorithms and Visualization in Medical Treament Planning}, series = {Visualization and Mathematics}, booktitle = {Visualization and Mathematics}, editor = {Hege, Hans-Christian and Polthier, Konrad}, publisher = {Springer-Verlag}, pages = {303 -- 328}, year = {1997}, language = {en} } @inproceedings{DeuflhardSeebassStallingetal.1997, author = {Deuflhard, Peter and Seebaß, Martin and Stalling, Detlev and Beck, Rudolf and Hege, Hans-Christian}, title = {Hyperthermia Treatment Planning in Clinical Therapy}, series = {Computational Physics, Chemistry and Biology (Proceedings of the 15th IMACS World Congress 1997 on Scientific Computation 3, Modelling and Applied Mathematics)}, booktitle = {Computational Physics, Chemistry and Biology (Proceedings of the 15th IMACS World Congress 1997 on Scientific Computation 3, Modelling and Applied Mathematics)}, editor = {Sydow, Achim}, publisher = {Wissenschaft und Technik Verlag}, pages = {9 -- 17}, year = {1997}, language = {en} } @inproceedings{DeuflhardSeebassStallingetal.1997, author = {Deuflhard, Peter and Seebass, Martin and Stalling, Detlev and Beck, Rudolf and Hege, Hans-Christian}, title = {Hyperthermia Treatment Planning in Clinical Cancer Therapy:Modelling, Simulation, and Visualization}, series = {Computational Physics, Chemistry and Biology}, volume = {3}, booktitle = {Computational Physics, Chemistry and Biology}, editor = {Sydow, Achim}, publisher = {Wissenschaft und Technik Verlag}, address = {Plenary keynote talk, 15th IMACS World Congress 1997 on Scientific Computation, Modelling and Applied Mathematics}, year = {1997}, language = {en} } @misc{DeuflhardSeebassStallingetal., author = {Deuflhard, Peter and Seebass, Martin and Stalling, Detlev and Beck, Rudolf and Hege, Hans-Christian}, title = {Hyperthermia Treatment Planning in Clinical Cancer Therapy: Modelling, Simulation and Visualization}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-2958}, number = {SC-97-26}, abstract = {\noindent The speaker and his co-workers in Scientific Computing and Visualization have established a close cooperation with medical doctors at the Rudolf--Virchow--Klinikum of the Humboldt University in Berlin on the topic of regional hyperthermia. In order to permit a patient--specific treatment planning, a special software system ({\sf\small HyperPlan}) has been developed. \noindent A mathematical model of the clinical system ({\it radio frequency applicator with 8 antennas, water bolus, individual patient body}) involves Maxwell's equations in inhomogeneous media and a so--called bio--heat transfer PDE describing the temperature distribution in the human body. The electromagnetic field and the thermal phenomena need to be computed at a speed suitable for the clinical environment. An individual geometric patient model is generated as a quite complicated tetrahedral ``coarse'' grid (several thousands of nodes). Both Maxwell's equations and the bio--heat transfer equation are solved on that 3D--grid by means of {\em adaptive} multilevel finite element methods, which automatically refine the grid where necessary in view of the required accuracy. Finally optimal antenna parameters for the applicator are determined . \noindent All steps of the planning process are supported by powerful visualization methods. Medical images, contours, grids, simulated electromagnetic fields and temperature distributions can be displayed in combination. A number of new algorithms and techniques had to be developed and implemented. Special emphasis has been put on advanced 3D interaction methods and user interface issues.}, language = {en} } @inproceedings{GellermannWustStallingetal.1997, author = {Gellermann, Johanna and Wust, Peter and Stalling, Detlev and Tilly, Wolfgang and Nadobny, Johanna and Seebass, Martin and Deuflhard, Peter and Felix, Roland and Budach, Volker}, title = {First Clinical Experiences with the Hyperthermia Planning System HyperPlan}, series = {Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997}, booktitle = {Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997}, pages = {79}, year = {1997}, language = {en} } @misc{ErdmannLangSeebass, author = {Erdmann, Bodo and Lang, Jens and Seebass, Martin}, title = {Adaptive Solutions of Nonlinear Parabolic Equations with Application to Hyperthermia Treatments}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-3130}, number = {SC-97-44}, abstract = {We present a self-adaptive finite element method to solve nonlinear evolution problems in 3D. An implicit time integrator of Rosenbrock type is coupled with a multilevel approach in space. The proposed method is applied to hyperthermia treatments to demonstrate its potential for the solving of complicated problems.}, language = {en} } @inproceedings{ErdmannLangSeebass1997, author = {Erdmann, Bodo and Lang, Jens and Seebass, Martin}, title = {Adaptive Solutions of Nonlinear Parabolic Equations with Application to Hyperthermia Treatments}, series = {CHT'97}, booktitle = {CHT'97}, editor = {de Vahl Davis, G. and Leonardi, E.}, address = {Cesme, Turkey}, pages = {103 -- 110}, year = {1997}, language = {en} } @inproceedings{NadobnyWustSeebassetal.1997, author = {Nadobny, Johanna and Wust, Peter and Seebass, Martin and Stalling, Detlev and Hege, Hans-Christian and Deuflhard, Peter and Felix, Roland}, title = {A Quantitative Comparison between the VSIE and the FDTD method using Electrically Equivalent Patient and Antenna Models}, series = {Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997}, booktitle = {Proc. 16th Ann. Meeting Europ. Soc. Hyperthermic Oncology (ESHO-97), Berlin, Germany, April 1997}, pages = {145}, year = {1997}, language = {en} } @misc{HegeSeebassStallingetal., author = {Hege, Hans-Christian and Seebass, Martin and Stalling, Detlev and Z{\"o}ckler, Malte}, title = {A Generalized Marching Cubes Algorithm Based on Non-Binary Classifications}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-2741}, number = {SC-97-05}, abstract = {We present a new technique for generating surface meshes from a uniform set of discrete samples. Our method extends the well-known marching cubes algorithm used for computing polygonal isosurfaces. While in marching cubes each vertex of a cubic grid cell is binary classified as lying above or below an isosurface, in our approach an arbitrary number of vertex classes can be specified. Consequently the resulting surfaces consist of patches separating volumes of two different classes each. Similar to the marching cubes algorithm all grid cells are traversed and classified according to the number of different vertex classes involved and their arrangement. The solution for each configuration is computed based on a model that assigns probabilities to the vertices and interpolates them. We introduce an automatic method to find a triangulation which approximates the boundary surfaces - implicitly given by our model - in a topological correct way. Look-up tables guarantee a high performance of the algorithm. In medical applications our method can be used to extract surfaces from a 3D segmentation of tomographic images into multiple tissue types. The resulting surfaces are well suited for subsequent volumetric mesh generation, which is needed for simulation as well as visualization tasks. The proposed algorithm provides a robust and unique solution, avoiding ambiguities occuring in other methods. The method is of great significance in modeling and animation too, where it can be used for polygonalization of non-manifold implicit surfaces.}, language = {en} }