@misc{SeebassBeckGellermannetal., author = {Seebass, Martin and Beck, Rudolf and Gellermann, Johanna and Nadobny, Jacek and Wust, Peter}, title = {Electromagnetic phased arrays for regional hyperthermia -- optimal frequency and antenna arrangement}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-5961}, number = {00-28}, abstract = {In this paper we investigate the effects of the three-dimensional arrangement of antennas and frequency on temperature distributions that can be achieved in regional hyperthermia using an electromagnetic phased array. We compare the results of power-based and temperature-based optimization. Thus we are able to explain the discrepancies between previous studies favouring more antenna rings on the one hand and more antennas per ring on the other hand. We analyze the sensitivity of the results with respect to changes in amplitudes and phases as well as patient position. This analysis can be used for different purposes. First, it provides additional criteria for selecting the optimal frequency. Second, it can be used for specifying the required phase and amplitude accuracy for a real phased array system. Furthermore, it may serve as a basis for technological developments in order to reduce both types of sensitivities described above.}, language = {en} } @misc{SeebassSullivanWustetal., author = {Seebass, Martin and Sullivan, Dennis and Wust, Peter and Deuflhard, Peter and Felix, Roland}, title = {The Berlin Extension of the Stanford Hyperthermia Treatment.}, url = {http://nbn-resolving.de/urn:nbn:de:0297-zib-1304}, number = {SC-93-35}, abstract = {In the field of deep regional hyperthermia, one of the most widely used devices is the BSD--2000 Hyperthermia System which employs the Sigma 60 applicator. The Sigma 60 consists of four independent sources, giving it the potential to control the energy pattern within the patient. The independent amplitudes and phases, as well as frequency selection and applicator position, present a large number of parameters for the operator to determine. Computer simulation has long been recognized as an attractive approach to optimizing these parameters. A treatment planning program was used in clinical practice at Stanford University Medical Center for two years. It demonstrated the feasibility of computer simulation for deep regional hyperthermia in a clinical situation. However, several parts of this system were written in a language specific to one workstation, which severely restricted the wider distribution of the program to other users of the Sigma 60. A new treatment planning system for the BSD 2000 has been developed and put into clinical practice at the Rudolf Virchow Clinic of the Free University of Berlin. The new method, which we will refer to as the Berlin system, has a simpler model construction program and a considerably better graphics capability. However, the most important feature is that all programs are written in FORTRAN, C, or the X Window graphics system. Therefore, the entire treatment planning system is completely portable to other workstations.}, language = {en} }