TY - JOUR
A1 - Sagnol, Guillaume
A1 - Harman, Radoslav
T1 - Computing exact D-optimal designs by mixed integer second-order cone programming
T2 - The Annals of Statistics
N2 - Let the design of an experiment be represented by an $s-$dimensional vector $w$ of weights with nonnegative components. Let the quality of $w$ for the estimation of the parameters of the statistical model be measured by the criterion of $D-$optimality, defined as the $m$th root of the determinant of the information matrix $M(w)=\sum_{i=1}^s w_i A_i A_i^T$, where $A_i$,$i=1,\ldots,s$ are known matrices with $m$ rows.
In this paper, we show that the criterion of $D-$optimality is second-order cone representable. As a result, the method of second-order cone programming can be used to compute an approximate $D-$optimal design with any system of linear constraints on the vector of weights. More importantly, the proposed characterization allows us to compute an exact $D-$optimal design, which is possible thanks to high-quality branch-and-cut solvers specialized to solve mixed integer second-order cone programming problems. Our results extend to the case of the criterion of $D_K-$optimality, which measures the quality of $w$ for the estimation of a linear parameter subsystem defined by a full-rank coefficient matrix $K$.
We prove that some other widely used criteria are also second-order cone representable, for instance, the criteria of $A-$, $A_K$-, $G-$ and $I-$optimality.
We present several numerical examples demonstrating the efficiency and general applicability of the proposed method. We show that in many cases the mixed integer second-order cone programming approach allows us to find a provably optimal exact design, while the standard heuristics systematically miss the optimum.
Y1 - 2015
UR - https://opus4.kobv.de/opus4-zib/frontdoor/index/index/docId/5955
VL - 43
IS - 5
SP - 2198
EP - 2224
ER -