Ingenieur- und Naturwissenschaften
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The tedious and time-consuming solvent exchange during aerogel production was sped up using a standard Soxhlet extractor. Optimizing the setup with a vent and molecular sieve allowed to save up to 80% of the production time compared to batchwise extractions while maintaining state-of-the-art samples of silica and polyurethane aerogels, i.e. MTMS aerogels with a thermal conductivity of 15 mW m−1 K−1 and PU aerogels with 17 mW m−1 K−1 and good mechanical properties even after freeze-drying, which is generally more stressful than supercritical drying. The syntheses had to be carried out in high-boiling solvents, but adaptation and optimisation were made possible rapidly due to the method developed.
When applying wood preservatives, there are always losses due to the tools used (e.g. brushes or cloths). Furthermore, inexperienced users often have the problem that uneven application leads to unsightly stains. The use of organogels could solve both challenges. In this work, sorbitol-based gelators were used to gel various liquid organic protective agents (in particular linseed oil and furniture wax oil) to produce a quasi-solid version. The properties of the gels were analysed rheologically, whereby it was found that at deformations between 1 % - 4 % the top layer of the gel structure breaks down and the protective agent is released. After coating beech wood, the transferred mass was determined and the protective layer was analyzed. The method saves over 20 % protective agent, without taking tool losses into account. Practial coating layers were found which did not differ in their performance to those from ungelled materials.
Folgt unsere Welt einem geregelten „Tanz der Materie“? Lässt sich Magie in die Leer-stellen persönlicher und wissenschaftlicher Erkenntnis hineindeuten? Die Autoren gehen grundlegenden Fragen naturwissenschaftlichen Denkens nach und verdeutlichen anhand anschaulicher Beispiele, was unklare Begriffe wie „Plausibilität“ in der Naturwissenschaft bedeuten, was „Empirie“ ist und was die naturwissenschaftliche Methode für unsere Sicht der Welt bewirkt. Auf diese Weise entzaubern sie die Argumente von Pseudo- und Anti-Wissenschaftlern und verteidigen die Naturwissenschaften gegen Missbrauch. Hemminger ist Biologe und Psychologe – vor seinem Ruhestand beriet er zuletzt die Evangelische Kirche in Fragen um Religionspsychologie und Sekten. Beyer ist Professor für Molekulare Biologie an der Westfälischen Hochschule Gelsenkirchen.
Determination of Thermal DNA-Stability With Respect to PCR or How to Debunk a Pseudoscientific Claim
(2026)
Debunking pseudoscience is difficult, especially for early-career students and the public. Recently, in particular the Corona pandemic has spawned a whole range of pseudoscientific claims and conspiracy theories, many of which are publicly available in the style of scientific articles on preprint servers, in predatory journals, or in some cases even as regular scientific papers making it difficult to distinguish scientific papers from pseudoscience. One example is a recently published paper claiming that PCR is unreliable because DNA is thermolabile. While experts have the skills to recognize such pseudoscience, inexperienced early-career students usually have few chances to critically evaluate such claims. Here, we present some simple experiments that combine several aspects: (I) the analysis of a seemingly reputable publication, (II) planning experiments on the physicochemistry of DNA, (III) conducting and analyzing these experiments, and finally (IV) the refutation of the claim that PCR is unreliable. These experiments can be carried out in any standard laboratory with basic molecular biology equipment. They are therefore suitable for undergraduate programs and for high school courses. The model case described here enables students to critically evaluate these claims through practical investigations and to form their own informed opinion. The participants gained new insights into the planning of experiments and a completely new perspective on the subject of science and pseudoscience.
The question of whether PCR is reliable sounds strange at first. However, looking at the scientific literature from the 1950s and 60s, one will find many publications on the physicochemistry of DNA that have been forgotten meanwhile. Quite a few of these studies have shown that DNA is thermolabile, which consequently raises the question of whether this thermolability is relevant in the context of PCR, namely in the denaturation phase. However, it can be shown that this is not the case: losses due to thermal hydrolysis are irrelevant for the performance of contemporary PCR protocols and their specificity as well as for the significance of their results. There is now a huge amount of scientifically verified and published data on technical and molecular aspects of PCR, a small selection of which we quote here. In addition, we present some primary data that also clearly demonstrate the reliability of PCR.
There are around 2,500 car wash lines in Germany, consuming around 30 million m3 of drinking water per year. In view of the increasing scarcity of water, this level of consumption could soon be restricted by law, as it is in some countries. There are only a few systematic studies on process water systems in car wash lines in Middle Europe; we therefore carried out a survey to determine process water quality parameters (COD, turbidity, water hardness, pH, conductivity, dissolved O2, and temperature). Data were collected and analysed from 63 different locations in Germany and the Netherlands. In addition, longitudinal parameters were measured for 1 year at a single state-of-the-art site in Germany. The scatter of the observed values was quite considerable. The average COD in water of car wash sites with biological treatment was found to be significantly lower than in car wash sites working with filter treatment. Overall, the deviation of the pollution parameters was higher than expected. Surprisingly, there is hardly any reliable data on freshwater consumption in the car wash facilities. As most of the long-established facilities do not have a modern water treatment system, freshwater consumption is up to 300 L per car washed.

