The SYSTERS Protein Family Database in 2005

  • The SYSTERS project aims to provide a meaningful partitioning of the whole protein sequence space by a fully automatic procedure. A refined two-step algorithm assigns each protein to a family and a superfamily. The sequence data underlying SYSTERS release 4 now comprise several protein sequence databases derived from completely sequenced genomes (ENSEMBL, TAIR, SGD and GeneDB), in addition to the comprehensive Swiss-Prot/TrEMBL databases. The SYSTERS web server (http://systers.molgen.mpg.de) provides access to 158 153 SYSTERS protein families. To augment the automatically derived results, information from external databases like Pfam and Gene Ontology are added to the web server. Furthermore, users can retrieve pre-processed analyses of families like multiple alignments and phylogenetic trees. New query options comprise a batch retrieval tool for functional inference about families based on automatic keyword extraction from sequence annotations. A new access point, PhyloMatrix, allows the retrieval of phylogenetic profiles of SYSTERS families across organisms with completely sequenced genomes.

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Author:Thomas Meinel, Antje Krause, Hannes Luz, Martin Vingron, Eike Staub
URN:urn:nbn:de:kobv:526-opus4-6476
DOI:https://doi.org/10.1093/nar/gki030
ISSN:1362-4962
Parent Title (English):Nucleic Acids Research
Document Type:Article
Language:English
Year of Publication:2004
Publishing Institution:Technische Hochschule Wildau
Release Date:2016/07/07
Volume:33
First Page:D226
Last Page:D229
Source:Thomas Meinel, Antje Krause, Hannes Luz, Martin Vingron, and Eike Staub. The SYSTERS Protein Family Database in 2005. Nucl. Acids Res. (2005) 33 (suppl 1): D226-D229 doi:10.1093/nar/gki030
Faculties an central facilities:Fachbereich Ingenieurwesen / Wirtschaftsingenieurwesen (bis 8/2014)
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Licence (German):Creative Commons - CC BY-NC 3.0 - Namensnennung-Nicht kommerziell 3.0 Unported
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