Conceptual study for long-term monitoring of chemotherapeutic induced cell reactions by ESPI
- During the last years, various approaches on an individualized drug therapy for benign cells have been researched. However, due to the complex topic a universal approach has not been found up until this point. Commonly, the effect of cytotoxic drugs on benign cells is in most cases the same compared to regular cells while the actual effect on patient still can't be predicted. In order to reduce unwanted side effects or unspecific drug reactions a test system for patients which allows to analyse the interaction between cytotoxic agents and the targeted cells is needed. Furthermore, this should also include an adequate measurement system which is capable to work in a natural environment and without any additional preparation. In terms of this work, a first proof of concept with different benign cells and cytotoxic agents is presented while monitoring the obtained displacement using electronic speckle pattern interferometry (ESPI).
Author: | Josefine Johanna Gottschalk, Carsten Stollfuß, Kai-Henning Lietzau, Andreas Foitzik, Maria RichettaORCiD |
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URN: | urn:nbn:de:kobv:526-opus4-10676 |
DOI: | https://doi.org/10.1515/teme-2017-0100 |
ISSN: | 2196-7113 |
Parent Title (English): | tm - Technisches Messen |
Document Type: | Article |
Language: | English |
Year of Publication: | 2017 |
Embargo Date: | 2018/11/27 |
Publishing Institution: | Technische Hochschule Wildau |
Release Date: | 2018/10/30 |
Tag: | ESPI; anticancer drug; cellular displacement; interferometry |
Volume: | 85 |
Issue: | 2 |
First Page: | 111 |
Last Page: | 118 |
Source: | Gottschalk, J., Stollfuß, C., Lietzau, K., et al. (2017). Conceptual study for long-term monitoring of chemotherapeutic induced cell reactions by ESPI. tm - Technisches Messen, 85(2), pp. 111-118. Retrieved 30 Oct. 2018, from doi:10.1515/teme-2017-0100 |
Faculties an central facilities: | Fachbereich Ingenieur- und Naturwissenschaften |
Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit | |
Licence (German): | Creative Commons - CC BY-NC-ND - Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International |