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Coupling biology to electrochemistry—future trends and needs

  • The coupling of biological entities with electrodes has already quite some history and has reached a status which is not only based on phenomenological descriptions. Nowadays, we are able to effectively couple redox centres within protein molecules to electrochemical transducers. This allows the transduction of a biochemical reaction into an electrode signal with applications mainly in sensing and bioenergetics [1,2,3,4,5,6,7,8]. However, in most cases, this coupling is not direct, and shuttle molecules or side products of the reaction are used. But also for the direct coupling, significant progress has been made, and several enzymes and redox proteins can be addressed directly by electrodes [8,9,10,11,12,13]. The understanding of the functioning of developed systems is, however, in its infancy. Charge and electrostatic interactions have been mostly studied, and for small dipole molecules such as cytochrome c, the situation can be well described [14]. There is a lack of understanding for more complex enzyme molecules which brings a lot of trial and error into research.

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Metadaten
Author:Fred LisdatORCiDGND
URN:urn:nbn:de:kobv:526-opus4-13639
DOI:https://doi.org/10.1007/s10008-020-04714-y
ISSN:1433-0768
Parent Title (English):Journal of Solid State Electrochemistry
Publisher:Springer Nature
Document Type:Article
Language:English
Year of Publication:2020
Publishing Institution:Technische Hochschule Wildau
Release Date:2021/01/08
Volume:24
First Page:2125
Last Page:2127
Source:Lisdat, F. (2020). Coupling biology to electrochemistry—future trends and needs Journal of Solid State Electrochemistry. 24, 2125–2127.
Faculties an central facilities:Fachbereich Ingenieur- und Naturwissenschaften
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 541 Physikalische Chemie
Funding:Projekt DEAL
Licence (German):Creative Commons - CC BY - Namensnennung 4.0 International
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