Silica nanoparticles for the layer-by-layer assembly of fully electro-active cytochrome c multilayers
- For bioanalytical systems sensitivity and biomolecule activity are critical issues. The immobilization of proteins into multilayer systems by the layer-by-layer deposition has become one of the favorite methods with this respect. Moreover, the combination of nanoparticles with biomolecules on electrodes is a matter of particular interest since several examples with high activities and direct electron transfer have been found. Our study describes the investigation on silica nanoparticles and the redox protein cytochrome c for the construction of electro-active multilayer architectures, and the electron transfer within such systems. The novelty of this work is the construction of such artificial architectures with a non-conducting building block. Furthermore a detailed study of the size influence of silica nanoparticles is performed with regard to formation and electrochemical behavior of these systems.
Author: | Sven Christian Feifel, Fred LisdatORCiDGND |
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URN: | urn:nbn:de:kobv:526-opus4-5819 |
DOI (Version of Record): | https://doi.org/10.1186/1477-3155-9-59 |
ISSN: | 1477-3155 |
Parent Title (English): | Journal of Nanobiotechnology |
Document Type: | Article |
Language: | English |
Year of Publication: | 2011 |
Date of first Publication: | 2011/12/30 |
Publishing Institution: | Technische Hochschule Wildau |
Contributing Corporation: | Institute for Thin Film and Microsensor Technologies; Department of Chemistry and Centre for NanoScience (CeNS), University of Munich (LMU) |
Release Date: | 2016/06/16 |
Volume: | 9 |
Issue: | 59 |
Page Number: | 12 |
Source: | Feifel and Lisdat. Journal of Nanobiotechnology. 2011, 9:59. http://www.jnanobiotechnology.com/content/9/1/59 |
Faculties an central facilities: | Fachbereich Ingenieurwesen / Wirtschaftsingenieurwesen (bis 8/2014) |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 66 Chemische Verfahrenstechnik / 660 Chemische Verfahrenstechnik |
Licence (German): | Creative Commons - CC BY - Namensnennung 2.0 Generic |