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Silica nanoparticles for the layer-by-layer assembly of fully electro-active cytochrome c multilayers

  • For bioanalytical systems sensitivity and biomolecule activity are critical issues. The immobilization of proteins into multilayer systems by the layer-by-layer deposition has become one of the favorite methods with this respect. Moreover, the combination of nanoparticles with biomolecules on electrodes is a matter of particular interest since several examples with high activities and direct electron transfer have been found. Our study describes the investigation on silica nanoparticles and the redox protein cytochrome c for the construction of electro-active multilayer architectures, and the electron transfer within such systems. The novelty of this work is the construction of such artificial architectures with a non-conducting building block. Furthermore a detailed study of the size influence of silica nanoparticles is performed with regard to formation and electrochemical behavior of these systems.

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Metadaten
Author:Sven Christian Feifel, Fred LisdatORCiDGND
URN:urn:nbn:de:kobv:526-opus4-5819
DOI (Version of Record):https://doi.org/10.1186/1477-3155-9-59
ISSN:1477-3155
Parent Title (English):Journal of Nanobiotechnology
Document Type:Article
Language:English
Year of Publication:2011
Date of first Publication:2011/12/30
Publishing Institution:Technische Hochschule Wildau
Contributing Corporation:Institute for Thin Film and Microsensor Technologies; Department of Chemistry and Centre for NanoScience (CeNS), University of Munich (LMU)
Release Date:2016/06/16
Volume:9
Issue:59
Page Number:12
Source:Feifel and Lisdat. Journal of Nanobiotechnology. 2011, 9:59. http://www.jnanobiotechnology.com/content/9/1/59
Faculties an central facilities:Fachbereich Ingenieurwesen / Wirtschaftsingenieurwesen (bis 8/2014)
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 66 Chemische Verfahrenstechnik / 660 Chemische Verfahrenstechnik
Licence (German):Creative Commons - CC BY - Namensnennung 2.0 Generic
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