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Validation of Material Parameters of Collagen Compositions for the Application as a Bioink

  • The novel approach of an individualized medicine affects nowadays various areas of therapeutic treatment. Primarily, these include the application of pharmaceuticals, private point-of-care solutions, surgical procedures as well as steps of rehabilitation. However, beside these existing strategies the development of patient specific models for the training of clinical personal is currently insufficient. Such models are essential to prepare a personalized approach of medical care. One possible solution to address this problem could be the adaption of the established 3d printing technology for the processing of suitable biopolymers. The presented work is focused on the development of a printing system utilizing collagen. Therefore, it is intended to design multiple extrusion heads in accordance with the material parameters. In order to achieve the aspired physiological properties of the final model, a first set of experiments will be performed with several compositions of collagen to validate the fundamental mechanical characteristics. Hereby, the elasticity, thermal stability, force resistance as well as the haptic behaviour are of most interest. Afterwards, these obtained experimental results should be used to simulate the extrusion process and to validate the extruder concepts. In case of a positive evaluation these concepts are realized by using rapid prototyping technologies. Finally, this novel 3d printer will be used to print first organic test structures with collagen.

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Metadaten
Author:Volker Schlegel, Andreas Engels, Stefano BifarettiORCiD, Andreas Foitzik
URN:urn:nbn:de:kobv:526-opus4-18764
DOI (Version of Record):https://doi.org/10.4028/www.scientific.net/MSF.941.2437
ISSN:0255-5476
ISSN:1662-9752
Parent Title (English):Materials Science Forum
Publisher:Trans Tech Publications
Document Type:Article
Language:English
Year of Publication:2018
Publishing Institution:Technische Hochschule Wildau
Release Date:2024/03/06
Tag:bio-ink; bioprinting; collagen; validation of material parameters
Volume:941
First Page:2437
Last Page:2441
Source:Schlegel, V., Engels, A., Bifaretti, S., & Foitzik, A. H. (2018). Validation of Material Parameters of Collagen Compositions for the Application as a Bioink. Materials Science Forum, 941, 2437–2441. https://doi.org/10.4028/www.scientific.net/msf.941.2437
Faculties an central facilities:Fachbereich Ingenieur- und Naturwissenschaften
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
6 Technik, Medizin, angewandte Wissenschaften / 62 Ingenieurwissenschaften / 620 Ingenieurwissenschaften und zugeordnete Tätigkeiten
Licence (German):DFG-geförderte Allianz- bzw. Nationallizenz
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